Multiphysics Modeling with Application to Biomedical Engineering

Multiphysics Modeling with Application to Biomedical Engineering PDF Author: Z. Yang
Publisher: CRC Press
ISBN: 100008891X
Category : Mathematics
Languages : en
Pages : 151

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Book Description
The aim of this book is to introduce the simulation of various physical fields and their applications for biomedical engineering, which will provide a base for researchers in the biomedical field to conduct further investigation. The entire book is classified into three levels. It starts with the first level, which presents the single physical fields including structural analysis, fluid simulation, thermal analysis, and acoustic modeling. Then, the second level consists of various couplings between two physical fields covering structural thermal coupling, porous media, fluid structural interaction (FSI), and acoustic FSI. The third level focuses on multi-coupling that coupling with more than two physical fields in the model. Each part in all levels is organized as the physical feature, finite element implementation, modeling procedure in ANSYS, and the specific applications for biomedical engineering like the FSI study of Abdominal Aortic Aneurysm (AAA), acoustic wave transmission in the ear, and heat generation of the breast tumor. The book should help for the researchers and graduate students conduct numerical simulation of various biomedical coupling problems. It should also provide all readers with a better understanding of various couplings.

Multiphysics Modeling with Application to Biomedical Engineering

Multiphysics Modeling with Application to Biomedical Engineering PDF Author: Z. Yang
Publisher: CRC Press
ISBN: 1000088871
Category : Mathematics
Languages : en
Pages : 175

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Book Description
The aim of this book is to introduce the simulation of various physical fields and their applications for biomedical engineering, which will provide a base for researchers in the biomedical field to conduct further investigation. The entire book is classified into three levels. It starts with the first level, which presents the single physical fields including structural analysis, fluid simulation, thermal analysis, and acoustic modeling. Then, the second level consists of various couplings between two physical fields covering structural thermal coupling, porous media, fluid structural interaction (FSI), and acoustic FSI. The third level focuses on multi-coupling that coupling with more than two physical fields in the model. Each part in all levels is organized as the physical feature, finite element implementation, modeling procedure in ANSYS, and the specific applications for biomedical engineering like the FSI study of Abdominal Aortic Aneurysm (AAA), acoustic wave transmission in the ear, and heat generation of the breast tumor. The book should help for the researchers and graduate students conduct numerical simulation of various biomedical coupling problems. It should also provide all readers with a better understanding of various couplings.

An Introduction to Modeling of Transport Processes

An Introduction to Modeling of Transport Processes PDF Author: Ashim Datta
Publisher: Cambridge University Press
ISBN: 0521119243
Category : Medical
Languages : en
Pages : 533

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Book Description
Organised around problem solving, this book introduces the reader to computational simulation, bridging fundamental theory with real-world applications.

Modelling Organs, Tissues, Cells and Devices

Modelling Organs, Tissues, Cells and Devices PDF Author: Socrates Dokos
Publisher: Springer
ISBN: 3642548016
Category : Technology & Engineering
Languages : en
Pages : 504

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Book Description
This book presents a theoretical and practical overview of computational modeling in bioengineering, focusing on a range of applications including electrical stimulation of neural and cardiac tissue, implantable drug delivery, cancer therapy, biomechanics, cardiovascular dynamics, as well as fluid-structure interaction for modelling of organs, tissues, cells and devices. It covers the basic principles of modeling and simulation with ordinary and partial differential equations using MATLAB and COMSOL Multiphysics numerical software. The target audience primarily comprises postgraduate students and researchers, but the book may also be beneficial for practitioners in the medical device industry.

Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology

Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology PDF Author: Willem L. van Meurs
Publisher: McGraw Hill Professional
ISBN: 0071714464
Category : Technology & Engineering
Languages : en
Pages : 216

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Book Description
THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation. A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications. Coverage includes: Signals and systems Model requirements Conceptual models Mathematical models Software implementation Simulation results and model validation Cardiorespiratory system model Circulation Respiration Physiologic control Sensitivity analysis of a cardiovascular model Design of model-driven acute care training simulators “Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). ...His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. ...The ample illustrations and tables also break up the text and make reading the book easier on the eyes. ...concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all these topics together under one cover and is an important contribution to biomedical literature.” --IEEE Pulse, January 2014 “This book is written by a professional engineer who is unique in that he seems to have a natural understanding of 3 key areas as follows: the hardware involved with simulators, human physiology, and mathematical modeling. Willem van Meurs is one of the inventors of the model-driven human patient simulator (HPS), and so, he is very qualified to write this book. The book is written in a clear way, using the first person throughout, in a conversational manner, with a style that involves posing questions and answering them in subsequent text. ...The book starts with a very useful introduction and background chapter, setting out the scene for the rest of the book. ...I have used his book in enhancing my own talks and understanding human patient simulation and can strongly recommend it.” --Simulation in Healthcare December, 2012 Reviewed by Mark A. Tooley, Ph.D., Department of Medical Physics and Bioengineering, Royal United Hospital, Combe Park, Bath, UK.

A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences

A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences PDF Author: Riccardo Sacco
Publisher: Academic Press
ISBN: 0128125195
Category : Technology & Engineering
Languages : en
Pages : 854

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Book Description
A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences provides a systematic methodology to the formulation of problems in biomedical engineering and the life sciences through the adoption of mathematical models based on physical principles, such as the conservation of mass, electric charge, momentum, and energy. It then teaches how to translate the mathematical formulation into a numerical algorithm that is implementable on a computer. The book employs computational models as synthesized tools for the investigation, quantification, verification, and comparison of different conjectures or scenarios of the behavior of a given compartment of the human body under physiological and pathological conditions. Presents theoretical (modeling), biological (experimental), and computational (simulation) perspectives Features examples, exercises, and MATLAB codes for further reader involvement Covers basic and advanced functional and computational techniques throughout the book

Computational Modeling in Biomedical Engineering and Medical Physics

Computational Modeling in Biomedical Engineering and Medical Physics PDF Author: Alexandru Morega
Publisher: Academic Press
ISBN: 0128178973
Category : Science
Languages : en
Pages : 320

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Book Description
Mathematical and numerical modelling of engineering problems in medicine is aimed at unveiling and understanding multidisciplinary interactions and processes and providing insights useful to clinical care and technology advances for better medical equipment and systems. When modelling medical problems, the engineer is confronted with multidisciplinary problems of electromagnetism, heat and mass transfer, and structural mechanics with, possibly, different time and space scales, which may raise concerns in formulating consistent, solvable mathematical models. Computational Medical Engineering presents a number of engineering for medicine problems that may be encountered in medical physics, procedures, diagnosis and monitoring techniques, including electrical activity of the heart, hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods. The authors discuss the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling (e.g., criteria for well-posed problems); physics scaling (homogenization techniques); Constructal Law criteria in morphing shape and structure of systems with internal flows; computational domain construction (CAD and, or reconstruction techniques based on medical images); numerical modelling issues, and validation techniques used to ascertain numerical simulation results. In addition, new ideas and venues to investigate and understand finer scale models and merge them into continuous media medical physics are provided as case studies. Presents the fundamentals of mathematical and numerical modeling of engineering problems in medicine Discusses many of the most common modelling scenarios for Biomedical Engineering, including, electrical activity of the heart hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods Includes discussion of the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling, physics scaling, Constructal Law criteria in morphing shape and structure of systems with internal flows, computational domain construction, numerical modelling issues, and validation techniques used to ascertain numerical simulation results

Multiphysics Modeling: Numerical Methods and Engineering Applications

Multiphysics Modeling: Numerical Methods and Engineering Applications PDF Author: Qun Zhang
Publisher: Elsevier
ISBN: 0124077374
Category : Technology & Engineering
Languages : en
Pages : 438

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Book Description
Multiphysics Modeling: Numerical Methods and Engineering Applications: Tsinghua University Press Computational Mechanics Series describes the basic principles and methods for multiphysics modeling, covering related areas of physics such as structure mechanics, fluid dynamics, heat transfer, electromagnetic field, and noise. The book provides the latest information on basic numerical methods, also considering coupled problems spanning fluid-solid interaction, thermal-stress coupling, fluid-solid-thermal coupling, electromagnetic solid thermal fluid coupling, and structure-noise coupling. Users will find a comprehensive book that covers background theory, algorithms, key technologies, and applications for each coupling method. Presents a wealth of multiphysics modeling methods, issues, and worked examples in a single volume Provides a go-to resource for coupling and multiphysics problems Covers the multiphysics details not touched upon in broader numerical methods references, including load transfer between physics, element level strong coupling, and interface strong coupling, amongst others Discusses practical applications throughout and tackles real-life multiphysics problems across areas such as automotive, aerospace, and biomedical engineering

Multiphysics Modeling Using COMSOL 5 and MATLAB

Multiphysics Modeling Using COMSOL 5 and MATLAB PDF Author: Roger W. Pryor
Publisher: Mercury Learning and Information
ISBN: 1683925882
Category : Technology & Engineering
Languages : en
Pages : 743

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Book Description
COMSOL 5 and MATLAB are valuable software modeling tools for engineers and scientists. This updated edition includes five new models and explores a wide range of models in coordinate systems from 0D to 3D, introducing the numerical analysis techniques employed in COMSOL 5.6 and MATLAB software. The text presents electromagnetic, electronic, optical, thermal physics, and biomedical models as examples. It presents the fundamental concepts in the models and the step-by-step instructions needed to build each model. The companion files include all the built models for each step-by-step example presented in the text and the related animations, as specified. The book is designed to introduce modeling to an experienced engineer or can also be used for upper level undergraduate or graduate courses. FEATURES: Focuses on COMSOL 5.x and MATLAB models that demonstrate the use of concepts for later application in engineering, science, medicine, and biophysics for the development of devices and systems Includes companion files with executable copies of each model and related animations Includes detailed discussions of possible modeling errors and results Uses a step-by-step modeling methodology linked to the Fundamental Laws of Physics. The companion files are also available online by emailing the publisher with proof of purchase at [email protected].

Introduction to Integrative Engineering

Introduction to Integrative Engineering PDF Author: Guigen Zhang
Publisher: CRC Press
ISBN: 1315388456
Category : Health & Fitness
Languages : en
Pages : 424

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Book Description
This textbook is designed for an introductory course at undergraduate and graduate levels for bioengineering students. It provides a systematic way of examining bioengineering problems in a multidisciplinary computational approach. The book introduces basic concepts of multidiscipline-based computational modeling methods, provides detailed step-by-step techniques to build a model with consideration of underlying multiphysics, and discusses many important aspects of a modeling approach including results interpretation, validation, and assessment.

Multiscale Modelling in Biomedical Engineering

Multiscale Modelling in Biomedical Engineering PDF Author: Dimitrios I. Fotiadis
Publisher: John Wiley & Sons
ISBN: 1119517346
Category : Science
Languages : en
Pages : 404

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Book Description
Multiscale Modelling in Biomedical Engineering Discover how multiscale modeling can enhance patient treatment and outcomes In Multiscale Modelling in Biomedical Engineering, an accomplished team of biomedical professionals delivers a robust treatment of the foundation and background of a general computational methodology for multi-scale modeling. The authors demonstrate how this methodology can be applied to various fields of biomedicine, with a particular focus on orthopedics and cardiovascular medicine. The book begins with a description of the relationship between multiscale modeling and systems biology before moving on to proceed systematically upwards in hierarchical levels from the molecular to the cellular, tissue, and organ level. It then examines multiscale modeling applications in specific functional areas, like mechanotransduction, musculoskeletal, and cardiovascular systems. Multiscale Modelling in Biomedical Engineering offers readers experiments and exercises to illustrate and implement the concepts contained within. Readers will also benefit from the inclusion of: A thorough introduction to systems biology and multi-scale modeling, including a survey of various multi-scale methods and approaches and analyses of their application in systems biology Comprehensive explorations of biomedical imaging and nanoscale modeling at the molecular, cell, tissue, and organ levels Practical discussions of the mechanotransduction perspective, including recent progress and likely future challenges In-depth examinations of risk prediction in patients using big data analytics and data mining Perfect for undergraduate and graduate students of bioengineering, biomechanics, biomedical engineering, and medicine, Multiscale Modelling in Biomedical Engineering will also earn a place in the libraries of industry professional and researchers seeking a one-stop reference to the basic engineering principles of biological systems.