Monoclonal Gammopathies and the Kidney PDF Download
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Author: G. Touchard
Publisher: Springer Science & Business Media
ISBN: 9401701911
Category : Medical
Languages : en
Pages : 305
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Book Description
The kidney involvement in monoclonal gammopathies is a fascinating field of research and of great concern to clinical practice. The book is divided into four parts. The first one is devoted to "the culprits" and includes contributions from leading investigators in B-cell proliferations, immunoglobulin synthesis, secretion and structure, light chain uptake and metabolism in the kidney. The second and third parts are devoted to "the victims": the tubule and the glomerulus. New insights into pathophysiology, clinical and histological features, treatment of renal lesions and therapy of B-cell proliferations are reported in myeloma cast nephropathy, Fanconi's syndrome, Randall-type monoclonal immunoglobulin deposition disease and non amyloid organized monoclonal immunoglobulin deposits. In the last part, immunoglobulinic amyloidosis is considered with a round table devoted to stem cell transplantation and new promising therapies in AL amyloidosis.
Author: G. Touchard
Publisher: Springer Science & Business Media
ISBN: 9401701911
Category : Medical
Languages : en
Pages : 305
Get Book Here
Book Description
The kidney involvement in monoclonal gammopathies is a fascinating field of research and of great concern to clinical practice. The book is divided into four parts. The first one is devoted to "the culprits" and includes contributions from leading investigators in B-cell proliferations, immunoglobulin synthesis, secretion and structure, light chain uptake and metabolism in the kidney. The second and third parts are devoted to "the victims": the tubule and the glomerulus. New insights into pathophysiology, clinical and histological features, treatment of renal lesions and therapy of B-cell proliferations are reported in myeloma cast nephropathy, Fanconi's syndrome, Randall-type monoclonal immunoglobulin deposition disease and non amyloid organized monoclonal immunoglobulin deposits. In the last part, immunoglobulinic amyloidosis is considered with a round table devoted to stem cell transplantation and new promising therapies in AL amyloidosis.
Author: Eric P. Cohen
Publisher: Oxford University Press, USA
ISBN: 0199580197
Category : Medical
Languages : en
Pages : 382
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Book Description
Cancer and the Kidney covers the challenging overlap area of nephrology and oncology, both in terms of kidney problems in cancer patients, and cancer that affects kidney patients, including assessment of kidney function, to paraneoplastic disorders, acquired cysts and native kidney cancers, and all points inbetween.
Author: Z.-H. Liui
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318026514
Category : Science
Languages : en
Pages : 274
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Book Description
The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.
Author: Kevin W. Finkel
Publisher: Elsevier Health Sciences
ISBN: 0323549616
Category : Medical
Languages : en
Pages : 498
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Book Description
Kidney disease and cancer are frequent comorbidities that require specialized knowledge and expertise from both the nephrologist and the oncologist. Written by three pioneers in this growing subspecialty, Onco-Nephrology provides authoritative, definitive coverage of the mechanism and management of these two life-threatening diseases. This unique, single-volume resource covers current protocols and recommends management therapies to arrest kidney failure and allow oncologic treatments to continue and succeed. - Addresses acute and chronic kidney diseases that develop from a variety of cancers. This includes direct kidney injury from the malignancy, paraneoplastic effects of the cancer, and various cancer agents used to treat the malignancy. - Discusses key issues regarding kidney disease in patients with cancer, including conventional chemotherapeutic regimens and new novel therapies (targeted agents and immunotherapies) or the malignancies themselves that may promote kidney injury; patients with chronic kidney disease who acquire cancer unrelated to renal failure; and kidney transplantation, which has been shown to carry an increased risk of cancer. - Contains dedicated chapters for each class of the conventional chemotherapeutic agents, targeted cancer agents, and cancer immunotherapies including the basic science, pathogenic mechanisms of injury, clinical manifestations, and treatment. - Includes special chapters devoted to the individual classes of chemotherapies that relate to kidney disease for quick reference. Discusses increasingly complex problems due to more numerous and specialized anti-cancer drugs, as well as increased survival rates for both cancer and renal failure requiring long-term patient care. - Covers anti-VEGF (antivascular endothelial growth factor) agents and cancer immunotherapies – treatments that are being recognized for adverse kidney effects. - Utilizes a clear, logical format based on the ASN Core Curriculum for Onco-Nephrology, making this reference an excellent tool for board review, as well as a practical resource in daily practice. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Author: Morie A. Gertz
Publisher: Springer Science & Business Media
ISBN: 1607616319
Category : Medical
Languages : en
Pages : 243
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Book Description
An up-to-date reference on this fascinating set of complex disorders, this book features the most comprehensive strategies for diagnosing, classifying, imaging, treating, and managing amyloidosis in multiple organ systems. Beneficial to the spectrum of practitioners from residents to sub-specialists, this book is a succinct authoritative text written by leaders in the field. The authors provide instruction on all forms of amyloidosis - including primary amyloidosis (AL), secondary amyloidosis (AA), and familial amyloidosis. With essential treatment algorithms, Amyloidosis: Diagnosis and Treatment is the gold-standard for all hematologists, oncologists, and internists caring for patients with this complex disease.
Author: Guillermo A. Herrera
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805581785
Category : Medical
Languages : en
Pages : 223
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Book Description
In recent years, the knowledge of how renal damage occurs in patients with plasma cell dyscrasias / myeloma has substantially increased. For the first time, this publication brings together issues relating to the diagnosis and pathogenesis of these disorders, as well as a summary of advances achieved in the treatment and management of patients. Several chapters are devoted to various glomerulopathies associated with deposition of immunoglobulin light and heavy chains, including those associated with amyloidosis. The sequential events are pointed out, crucial steps and key molecules open to modulation or control are delineated, and therapeutic advances are highlighted. Although the emphasis is on the management of cases with renal involvement, a distinct focus on the diseases as a whole and their impact on patients' general health and prognosis has been maintained throughout the discussions. Using a translational approach to renal manifestations in patients with plasma cell dyscrasias / myelomas, this publication conveys a comprehensive state-of-the-art view of the subject. It is aimed at practicing renal pathologists, nephrologists, internists and hematologists, as well as at trainees and scientists working in these specialties.
Author: Morie A. Gertz
Publisher: Springer Science & Business Media
ISBN: 1461485207
Category : Medical
Languages : en
Pages : 311
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Book Description
This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.
Author: Xin J. Zhou
Publisher: Cambridge University Press
ISBN: 1316613984
Category : Medical
Languages : en
Pages : 691
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Book Description
An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.
Author: Howard Trachtman
Publisher: Springer
ISBN: 9783319493787
Category : Medical
Languages : en
Pages : 0
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Book Description
This Handbook serves as a convenient, state-of-the-art and comprehensive resource on the pathogenesis, diagnosis, and treatment of glomerular diseases. Clinical approaches, modalities and challenges are provided, along with new developments since the publication of Kidney Disease Improving Global Outcomes (KDIGO): Glomerulonephritis. Chapters dedicated to glomerular diseases mirror the current classification schemes used by Nephrologists and Pathologists and will include definition and natural history, epidemiology, clinical manifestations, pathology, diagnosis, differential diagnosis, treatment (algorithms when appropriate), prognosis and future prospects and current direction of research. Contributing authors consist of internationally renowned glomerulonephritis experts, renal pathologists and clinical nephrologists who are engaged in the management of glomerular diseases in clinical pediatric and internal medicine practices. Glomerulonephritis fills a considerable knowledge gap for general nephrologists, providers involved with the care of patients with glomerular diseases, and researchers. It should also be of value to medical students, interns, residents and fellows, as well as all clinicians engaged in medical education.
Author: Fernando C. Fervenza
Publisher: Springer Science & Business Media
ISBN: 146148166X
Category : Medical
Languages : en
Pages : 420
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Book Description
Core Concepts in Parenchymal Kidney Disease provides comprehensive and state-of-the-art information on the diagnosis, treatment, classification and pathogenesis of glomerular and tubulointerstitial diseases. Chapters feature various clinical scenarios and are authored by a team of renowned experts in the field. Experienced clinicians and trainees alike will find this authoritative reference to be a valuable resource and contribution to the literature.
