Molecular Pharmacology and Pathology of Strokes

Molecular Pharmacology and Pathology of Strokes PDF Author: Joen-Rong Sheu
Publisher: MDPI
ISBN: 3038975419
Category : Biochemistry
Languages : en
Pages : 153

Get Book

Book Description
This book is a printed edition of the Special Issue "Molecular Pharmacology and Pathology of Strokes" that was published in IJMS

Molecular Pharmacology and Pathology of Strokes

Molecular Pharmacology and Pathology of Strokes PDF Author: Joen-Rong Sheu
Publisher: MDPI
ISBN: 3038975419
Category : Biochemistry
Languages : en
Pages : 153

Get Book

Book Description
This book is a printed edition of the Special Issue "Molecular Pharmacology and Pathology of Strokes" that was published in IJMS

Molecular Pharmacology and Pathology of Strokes

Molecular Pharmacology and Pathology of Strokes PDF Author: Howard Prentice
Publisher:
ISBN: 9783038975427
Category : Electronic books
Languages : en
Pages : 1

Get Book

Book Description
Stroke, a progressively non-communicable disease, is the second leading cause of death after coronary heart disease in developed countries. The present treatment options for stroke are adapting lifestyle practices, diabetes treatment, drugs, and the management of other factors, but no cure is yet available, despite new insights into molecular and therapeutic targets. Discoveries related to explicating the molecular pharmacology in cerebrovascular function and thrombosis have led to significant advancements in the current treatment paradigm for patients with stroke. Hence, this Special Issue invited scientific papers and reviews from researchers to provide solid evidence from a molecular point of view to scrutinize the molecular pharmacology and pathology of strokes. Platelet activation plays a major role in cardio and cerebrovascular diseases. Platelets also play a key role in the hemostatic process and are associated with various pathological events, such as arterial thrombosis and atherosclerosis. While the currently used anti-platelet drugs such as aspirin and clopidogrel demonstrate efficacy in many patients, they exert undesirable side effects. Therefore, the development of effective therapeutic strategies for the prevention and treatment of thrombotic diseases is a significant priority. Recently, precious metal drugs have conquered the subject of metal-based drugs, and several investigators have moved their attention to the synthesis of various ruthenium (Ru) and iridium (Ir) complexes due to their prospective therapeutic values. We have published this e-book about the "Molecular Pharmacology and Pathology of Strokes" and anticipate that readers will find this book useful regarding the significant challenges and current advances that are presently being made in stroke research, with the possibility of inspiring the application of novel drug development to enrich the devotion and treatment of patients with cardiovascular diseases.

Stroke

Stroke PDF Author: A David Mendelow
Publisher: Elsevier Health Sciences
ISBN: 0323295444
Category : Medical
Languages : en
Pages : 1481

Get Book

Book Description
Offered in print, online, and downloadable formats, this updated edition of Stroke: Pathophysiology, Diagnosis, and Management delivers convenient access to the latest research findings and management approaches for cerebrovascular disease. Picking up from where J. P. Mohr and colleagues left off, a new team of editors - Drs. Grotta, Albers, Broderick, Kasner, Lo, Mendelow, Sacco, and Wong - head the sixth edition of this classic text, which is authored by the world's foremost stroke experts. Comprehensive, expert clinical guidance enables you to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Abundant full-color CT images and pathology slides help you make efficient and accurate diagnoses. Data from late-breaking endovascular trials equips you with recent findings. Includes comprehensive coverage of advances in molecular biology of cell death; risk factors and prevention; advances in diagnostics and stroke imaging; and therapeutic options, including a thorough review of thrombolytic agents and emerging data for endovascular therapy. Features brand-new chapters on Intracellular Signaling: Mediators and Protective Responses; The Neurovascular Unit and Responses to Ischemia; Mechanisms of Cerebral Hemorrhage; Stroke Related to Surgery and Other Procedures; Cryptogenic Stroke; and Interventions to Improve Recovery after Stroke. Highlights new information on genetic risk factors; primary prevention of stroke; infectious diseases and stroke; recovery interventions such as robotics, brain stimulation, and telerehabilitation; and trial design. Details advances in diagnostic tests, such as ultrasound, computed tomography (including CT angiography and CT perfusion), MRI (including MR perfusion techniques), and angiography. Includes extracted and highlighted evidence levels. Expert Consult eBook version included with print purchase. This enhanced eBook experience allows you to search all of the text, figures, and references on a variety of devices. The content can also be downloaded to tablets and smart phones for offline use. Combat stroke with the most comprehensive and updated multimedia resource on the pathophysiology, diagnosis, and management of stroke from leaders in the field

Textbook of Stroke Medicine

Textbook of Stroke Medicine PDF Author: Michael Brainin
Publisher: Cambridge University Press
ISBN: 1107047498
Category : Medical
Languages : en
Pages : 425

Get Book

Book Description
Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.

Oxford Textbook of Stroke and Cerebrovascular Disease

Oxford Textbook of Stroke and Cerebrovascular Disease PDF Author: Bo Norrving
Publisher: Oxford Textbooks in Clinical N
ISBN: 019964120X
Category : Medical
Languages : en
Pages : 306

Get Book

Book Description
This practical volume covers the current pedagogic principles of stroke disease and care, including the acute hospital phase, public health issues, prevention, long-term management, and silent vascular disease.

Transient Ischemic Attack and Stroke

Transient Ischemic Attack and Stroke PDF Author: Sarah T. Pendlebury
Publisher: Cambridge University Press
ISBN: 0521735122
Category : Medical
Languages : en
Pages : 407

Get Book

Book Description
Accessible handbook covering the investigation, diagnosis and management of transient ischemic attacks and minor strokes.

Physiology, Pharmacology and Pathology of the Blood-Brain Barrier

Physiology, Pharmacology and Pathology of the Blood-Brain Barrier PDF Author: Zameel Cader
Publisher: Springer Nature
ISBN: 3030996549
Category : Medical
Languages : en
Pages : 362

Get Book

Book Description
This book presents a comprehensive collection of current knowledge and leading research about the blood-brain barrier. The chapters are organized in four main parts providing basic information and novel insights about the physiology of the blood-brain barrier, the challenges related to finding and developing drugs crossing the blood-brain barrier, experimental methods to study the blood-brain barrier and the role of the blood-brain barrier in disease mechanisms and its consequences for drug development. In the first part the readers will discover the structure, function and developmental aspects of the blood-brain barrier and gain novel insights into the complexity and functionality of the neurovascular unit and energy metabolism of brain endothelial cells. Chapters of the second part focus on translational challenges from the bench to the bedside in CNS drug development, shed light on the importance to understand the brain distribution of drugs related to their efficacy, elaborate on general pharmacokinetic considerations for CNS drugs and introduce current and novel drug delivery strategies to overcome the blood-brain barrier. The experimental part of the book covers mathematical and in vitro models as well as animal and human methods in blood-brain barrier research. Specific emphasis is set on the description of the methods, the role of species differences for data interpretation, novel human models based on stem cells with the potential for personalized medicine and technical considerations and tips helpful for readers interested in working with these models. In the fourth part particular attentions is given to the blood-brain barrier, its changes and participation during disease progression. Chapters summarize alterations of the blood-brain barrier that are present in common disorders such as Alzheimer’s disease, multiple sclerosis, stroke, traumatic brain injury, epilepsy and brain tumors. Present therapies will be discussed and the consequences for novel treatment approaches that need to bypass the blood-brain-barrier will be explored. In addition, experts discuss the question in how far changes at the blood-brain barrier are causally linked to disease progressions and consequently could serve as therapeutic targets. This collection is designed to appeal to a wide readership from students through basic and applied scientist to pharmacologists, medical doctors and stakeholders from the pharmaceutical industry and regulatory affairs. Due its comprehensive content the book has the potential to become a standard work in the field of blood-brain barrier research.

Progress in Pathology and Drug Development of Metabolic Disease

Progress in Pathology and Drug Development of Metabolic Disease PDF Author: Ping Zhou
Publisher: Frontiers Media SA
ISBN: 2832527949
Category : Science
Languages : en
Pages : 194

Get Book

Book Description


Stroke Medicine

Stroke Medicine PDF Author: Hugh Markus
Publisher: Oxford University Press
ISBN: 0198737882
Category : Medical
Languages : en
Pages : 609

Get Book

Book Description
A practical handbook written for the practising physician, 'Stroke Medicine' provides an up-to-date, and easily accessible source of information on all aspects of stroke care from acute care, through to rehabilitation and secondary prevention.

Cellular and Molecular Pathobiology of Cardiovascular Disease

Cellular and Molecular Pathobiology of Cardiovascular Disease PDF Author: Monte Willis
Publisher: Academic Press
ISBN: 0124055257
Category : Medical
Languages : en
Pages : 339

Get Book

Book Description
Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology