Molecular Pathology of Pituitary Adenomas PDF Download
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Author: Cristiana Tanase
Publisher: Elsevier
ISBN: 0124158307
Category : Medical
Languages : en
Pages : 129
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Book Description
The pituitary gland is an important one since it controls several of the other hormone glands, such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth or tumor in this gland, and they are the subject of very active clinical and pathological research. This book examines the latest developments in this field and discusses the most important molecules implicated in apoptosis, angiogenesis and signal transduction. A good understanding of these processes is needed to identify the best therapies. Facilitates the understanding of the processes involved and how they are translated into therapy Illustrations are used to explain the complex mechanisms involved
Author: Cristiana Tanase
Publisher: Elsevier
ISBN: 0124158307
Category : Medical
Languages : en
Pages : 129
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Book Description
The pituitary gland is an important one since it controls several of the other hormone glands, such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth or tumor in this gland, and they are the subject of very active clinical and pathological research. This book examines the latest developments in this field and discusses the most important molecules implicated in apoptosis, angiogenesis and signal transduction. A good understanding of these processes is needed to identify the best therapies. Facilitates the understanding of the processes involved and how they are translated into therapy Illustrations are used to explain the complex mechanisms involved
Author: Constantine A. Stratakis
Publisher: Academic Press
ISBN: 0128145382
Category : Science
Languages : en
Pages : 312
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Book Description
Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim's appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies. - Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of acromegaly and gigantism - Provides a unique compendium of endocrinology, genetics, clinical diagnosis and therapeutics - Contains contributions from internationally known experts who have treated patients with acromegaly and gigantism
Author: Vania Nosé
Publisher: Elsevier Health Sciences
ISBN: 0323554660
Category : Medical
Languages : en
Pages : 797
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Book Description
Part of the highly regarded Diagnostic Pathology series, this updated volume by Dr. Vania Nosé is a visually stunning, easy-to-use reference covering 125 of the most common endocrine pathology diagnoses. Outstanding images—more than 2,400 in all—make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This second edition incorporates the most recent clinical, pathological, histological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Essential knowledge in all areas of endocrine pathology, including thyroid, parathyroid, pituitary, adrenal, pancreas, skin, and inherited tumor syndromes Unsurpassed visual coverage with more than 2,400 carefully annotated clinical images, gross pathology, histology, and special and immunohistochemical stains that provide clinically and diagnostically important information on typical and variant disease features Designed to help you identify crucial elements of each diagnosis along with associated differential diagnoses and pitfalls to more quickly resolve problems during routine sign out of cases Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index Thoroughly updated content throughout, reflecting new WHO classifications for endocrine diseases, recently discovered and newly described endocrine disease entities and genetic causes, and treatment changes of endocrine diseases New coverage of encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC), with a new chapter on the new entity NIFTP, new genetic discoveries in the development of pheochromocytoma and paragangliomas, new names that demonstrate the differentiation of certain tumors, and new information on immunoglobulin G4-related disease (IgG4-RD) involving thyroid Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Author: Jean-François Bonneville
Publisher: Springer
ISBN: 3319290436
Category : Medical
Languages : en
Pages : 382
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Book Description
This clinically oriented book will familiarize the reader with all aspects of the diagnosis of tumors and other disorders of the pituitary gland by means of magnetic resonance imaging (MRI). The coverage includes acromegaly, Cushing’s disease, Rathke cleft cysts, prolactinomas, incidentalomas, nonsecreting adenomas, other lesions of the sellar area, hypophysitis, and central diabetes insipidus. Normal radiologic anatomy and the numerous normal variants are described, and guidance is also provided on difficulties, artifacts, and other pitfalls. The book combines concise text and high-quality images with a question and answer format geared toward the needs of the practitioner. MRI is today considered the cornerstone in the diagnosis of diseases of the hypophyseal-hypothalamic region but the relatively small size of the pituitary gland, its deep location, the many normal anatomic variants, and the often tiny size of lesions can hinder precise evaluation of the anatomic structures and particularly the pituitary gland itself. Radiologists and endocrinologists will find MRI of the Pituitary Gland to be full of helpful information on this essential examination, and the book will also be of interest to internists and neurosurgeons.
Author: Mark R. Wick
Publisher: Cambridge University Press
ISBN: 9781107022836
Category : Medical
Languages : en
Pages : 0
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Book Description
Silverberg's Principles and Practice of Surgical Pathology and Cytopathology is one of the most durable reference texts in pathology. Thoroughly revised and updated, this state-of-the-art new edition encompasses the entire fields of surgical pathology and cytopathology in a single source. Its practice-oriented format uniquely integrates these disciplines to present all the relevant features of a particular lesion, side by side. Over 4000 color images depict clinical features, morphological attributes, histochemical and immunohistochemical findings, and molecular characteristics of all lesions included. This edition features new highly experienced and academically accomplished editors, while chapters are written by the leading experts in the field (several new to this edition, bringing a fresh approach). Dr Steven Silverberg's practical approach to problem solving has been carefully preserved. The print book is packaged with access to a secure, electronic copy of the book, providing quick and easy access to its wealth of text and images.
Author: Nicholas A. Tritos
Publisher: Springer
ISBN: 3030118363
Category : Medical
Languages : en
Pages : 249
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Book Description
This unique book will serve as a valuable resource for clinicians and researchers interested in prolactin physiology and pathophysiology and those who are involved in the care of patients with related disorders, including hyperprolactinemia and prolactin-secreting pituitary adenomas. Timely and up-to-date, it opens with a review of the historical aspects of prolactin research and a discussion of pituitary anatomy and physiology. Several chapters examine basic and translational aspects of prolactin physiology, focusing on recent developments and future directions. The main portion of the book is comprised of chapters presenting the clinical aspects of prolactin excess or deficiency, with particular emphasis placed on prolactin-secreting pituitary adenomas and co-secreting tumors. Concluding chapters address prolactin-secreting pituitary adenomas in special populations – women in the preconception period or during pregnancy, children and adolescents, and men – as well as plurihormonal and aggressive adenomas and carcinomas. Written and edited by experts in the field, Prolactin Disorders will be a ready reference for a diverse array of professionals, from basic scientists to clinical investigators and clinicians from several specialties, including specialists in endocrinology, neurosurgery, radiation oncology and neuro-oncology.
Author: Ronald A. DeLellis
Publisher: IARC
ISBN: 9789283224167
Category : Medical
Languages : en
Pages : 324
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Book Description
This vol. was produced in collaboration with the International Academy of Pathology (IAP). - This publication reflects the views of a working group that convened for an editorial and consensus conference in Lyon, France, April 23-26, 2003
Author: George Kontogeorgos
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318010782
Category : Medical
Languages : en
Pages : 311
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Book Description
Molecular pathology, a newly emerging field of research, is providing a deeper insight and understanding of the pituitary structure and its function in health and disease. This volume covers the basic principles of molecular pathology and summarizes the current knowledge of pituitary development as well as pituitary adenoma morphology and pathogenesis. Molecular, state-of-the-art techniques currently used for research and clinical applications are presented and the results of these fascinating and sophisticated modern tools are illustrated. The contents cover topics such as the mechanisms involved in pituitary development and cytogenesis, tumor development and functional differentiation, cell death, the molecular cytogenetics of defective genes and chromosomes, and pituitary tumor formation and progression. The contributors all are internationally well-known and esteemed experts. The chapters are comprehensive and up to date and focus on recent advances and should stimulate further studies. The present volume of Frontiers of Hormone Research will be of particular interest not only to basic scientists, but also pathologists, clinical endocrinologists and neurosurgeons.
Author: Emmanuel Jouanneau
Publisher: Springer Nature
ISBN: 3030411761
Category : Medical
Languages : en
Pages : 233
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Book Description
This volume focuses on adult craniopharyngiomas, offering various perspectives. The first part of the book provides an up-to-date overview of the pathogenesis and management of adult craniopharyngiomas, helping readers understand the pathogenesis and molecular pathways. It highlights the importance of animal models for addressing molecular keys and for developing targeted therapies. The second part deals with clinical management, detailing the latest results in the era of endoscopic surgery, including the major contribution of the extended nasal endoscopic approaches for suprasellar and retrochiasmatic tumors. The book also discusses the key aspects of these tumors and how to manage them. The last part of the book addresses the future therapies and recurrences after surgery and radiotherapy. This volume is of interest to neurosurgeons, endocrinologists, paediatricians, radiologists and oncologists.
Author: Ozgur Mete
Publisher: Cambridge University Press
ISBN: 1107443318
Category : Medical
Languages : en
Pages : 1091
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Book Description
A much-needed comprehensive resource, Endocrine Pathology covers clinical, radiologic, biochemical, molecular, cytogenetic, immunologic and histopathologic aspects of endocrine disorders, including the full spectrum of both neoplastic and non-neoplastic lesions. The first section of the book provides an overview of the clinical presentations of endocrine diseases, while the second section reviews the wide variety of investigative techniques used in their diagnosis. The third and largest section provides a comprehensive tissue- and organ-based approach to the diagnosis of endocrine disorders, including morphologic, genetic and proteomic features with clinicopathologic correlations. All chapters are richly illustrated with numerous color images, tables and algorithms, and the book is packaged with a password, giving the user online access to all text and images. Written and edited by the world's leading experts, this comprehensive and up-to-date book is the definitive resource on endocrine pathology for all pathologists, endocrinologists and researchers.
