Author: Michael M. Gottesman
Publisher:
ISBN:
Category : Cytogenetics
Languages : en
Pages : 609

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Book Description

Author: George M. Malacinski
Publisher: Free Press
ISBN:
Category : Science
Languages : en
Pages : 424

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Book Description

Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0

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Book Description

Author: Michael M. Gottesman
Publisher:
ISBN:
Category : Cytogenetics
Languages : en
Pages : 609

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Book Description
Strategies needed to isolate mutant cell lines and to use the mutants to clone and map the genes are presented in detail. This is the first book in which such methodology and molecular biology are combined. The preferred cell lines for genetic analysis are presented in the first section, followed by special techniques for isolating a wide range of mutants. The remainder of the book is devoted to genetic mapping and cloning of mutant genes. The final section presents special techniques in gene regulation.

Author: George M. Malacinski
Publisher: Macmillan Publishing Company
ISBN: 9780070397552
Category : Science
Languages : en
Pages : 389

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Book Description

Author: Fumiaki Uchiumi
Publisher: BoD – Books on Demand
ISBN: 9535138553
Category : Medical
Languages : en
Pages : 336

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Book Description
"Central dogma" was presented by Dr. Francis Crick 60 years ago. The information of nucleotide sequences on DNAs is transcribed into RNAs by RNA polymerases. We learned the mechanisms of how transcription determines function of proteins and behaviour of cells and even how it brings appearances of organisms. This book is intended for scientists and medical researchers especially who are interested in the relationships between transcription and human diseases. This volume consists of an introductory chapter and 14 chapters, divided into 4 parts. Each chapter is written by experts in the basic scientific field. A collection of articles presented by active and laboratory-based investigators provides recent advances and progresses in the field of transcriptional regulation in mammalian cells.

Author: Malacinski G. M. Ed
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description

Author: Jeffrey H. Miller
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 188

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Book Description

Author: William C. Heiser
Publisher: Springer Science & Business Media
ISBN: 1592596509
Category : Science
Languages : en
Pages : 561

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Book Description
The efficiency of delivering DNA into mammalian cells has increased t- mendously since DEAE dextran was first shown to be capable of enhancing transfer of RNA into mammalian cells in culture. Not only have other chemical methods been developed and refined, but also very efficient physical and viral delivery methods have been established. The technique of introducing DNA into cells has developed from transfecting tissue culture cells to delivering DNA to specific cell types and organs in vivo. Moreover, two important areas of biology—assessment of gene function and gene therapy—require succe- ful DNA delivery to cells, driving the practical need to increase the efficiency and efficacy of gene transfer both in vitro and in vivo. TM These two volumes of the Methods in Molecular Biology series, Gene Del- ery to Mammalian Cells, are designed as a compendium of those techniques that have proven most useful in the expanding field of gene transfer in mammalian cells. It is intended that these volumes will provide a thorough background on chemical, physical, and viral methods of gene delivery, a synopsis of the myriad techniques currently available to introduce genes into mammalian cells, as well as a practical guide on how to accomplish this. It is my expectation that it will be useful to the novice in the field as well as to the scientist with expertise in gene delivery.

Author: Tom Strachan
Publisher: Garland Science
ISBN: 1136844074
Category : Science
Languages : en
Pages : 808

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Book Description
Human Molecular Genetics is an established and class-proven textbook for upper-level undergraduates and graduate students which provides an authoritative and integrated approach to the molecular aspects of human genetics. While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject. The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.