Molecular Genetics of Hypertension and Related Traits PDF Download
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Author: Markus Perola
Publisher:
ISBN: 9789517401241
Category :
Languages : en
Pages : 90
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Book Description
Author: Markus Perola
Publisher:
ISBN: 9789517401241
Category :
Languages : en
Pages : 90
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Book Description
Author: Madhu Khullar
Publisher: BoD – Books on Demand
ISBN: 9535102826
Category : Medical
Languages : en
Pages : 250
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Book Description
This book, authored by renowned researchers in the field of Hypertension Research, details the state of the art knowledge in genetics, genomics and pathophysiology of Essential hypertension, specifically the genetic determinants of hypertension and role of gene variants in response to anti-hypertensive therapy. Two chapters describe mitochondrial mutations in Essential hypertension and in hypertension associated Left ventricular hypertrophy, one chapter reviews in detail the global gene expression in hypertension, and an up to date treatise on pathophysiology of resistant hypertension is detailed in another chapter. Other topics included in the book are end organ damage, baroreceptor sensitivity and role of music therapy in essential hypertension.
Author:
Publisher: Academic Press
ISBN: 9780122204302
Category : Science
Languages : en
Pages : 0
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Book Description
This is a rapidly expanding research area, with most current publications existing as journal articles, or as single chapters in larger volumes. This will be one of the first books to bring all this information together into a comprehensive review volume, aimed at both researchers and clinicians. Hypertension is a condition in humans which is characterized by persistently high arterial blood pressure (over 140/90 mm Hg). Affected individuals are at risk from heart disease, stroke and kidney failure. This important disease affects a huge number of people worldwide, and therefore the study of the disease is of vital clinical importance. Hypertension is a genetically determined disease, with many other contributing factors. Research has expanded rapidly in this area, particularly over the last decade, and there are continuing advances in our understanding of the disease.
Author: Anna F. Dominiczak
Publisher: Elsevier Health Sciences
ISBN: 0444514562
Category : Medical
Languages : en
Pages : 284
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Book Description
Classic and modern tools of genetics have been applied to hypertension research for some 20 years. This volume in the Handbook of Hypertension series aims to go beyond a simple summary of discoveries and provides a critical commentary on many controversial issues. It will be particularly useful for clinician scientists at all stages of their careers, graduate students and post-doctoral scientists as well as all those interested in cardiovascular medicine and research throughout the entire spectrum from bench to bedside. As in every relatively young area of research, the initial excitement over the early positive observations has not always been confirmed by subsequent larger studies with greater statistical power. Issues related to current recommendations on design of studies and their analysis are therefore included. Pharmacogenetics and pharmacogenomics have been the subjects of many debates in recent years and are of particular importance in hypertension as life-long treatments, frequently with multiple drugs are given to millions of people world-wide. A critical appraisal of this controversial topic is provided. Several chapters on experimental genetics of hypertension with a special focus on physiological genomics are also included.
Author: Wybren de Jong
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 664
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Book Description
Hardbound. This volume is a worthy successor to volume 4 by virtue of its focus on the recent conceptual revolution in fundamental hypertension research. Without neglecting the heritage of earlier achievements, it highlights such brilliant breakthroughs in molecular genetics as the creation of transgenic animals as a source of a new pathogenesis of hypertension.A core of (patho)physiological mechanisms operative in experimental hypertension is provided, including several which act to maintain a normotensive state. The volume provides background and technical information on the use of different models of hypertension in a variety of animal species. A wealth of new information regarding the several different complications observed in genetic and other models of hypertension, as well as new animal models dedicated to these aspects, are also presented. Furthermore, new chapters addressing genotyping and the use of transgenics in hypertension are included.
Author: Xi Cheng
Publisher: Biota Publishing
ISBN: 161504695X
Category : Medical
Languages : en
Pages : 67
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Book Description
Hypertension, or elevated blood pressure, is a major risk factor for various cardiovascular, renal diseases, and stroke. The form of hypertension with no identifiable cause is referred to as Essential Hypertension. Familial studies indicate that Essential Hypertension is heritable and, thereby, classical genetic approaches have been applied on both human and other mammalian models of hypertension to map the locations of the allelic variants within quantitative trait loci for blood pressure. The post genome era has further elevated this area of research into large-scale genome-wide association studies of hypertension in humans. Collectively, these studies have resulted in the prioritization and cataloging of several genomic regions containing allelic variants as candidates linked or associated with essential hypertension. Further, they are providing evidence to suggest that the inheritance of hypertension is rather complex, encompassing multiple variants both within protein-coding and non-coding annotations, each of which may act independently or interactively with other genes and/or environmental factors to differentially regulate blood pressure. This book provides an overview of the various methods employed to study the genetics of hypertension and discuss the progress and prospects of this area of research that may contribute towards individualized clinical management of hypertension in the future.
Author: F. Soubrier
Publisher: R. G. Landes
ISBN: 9780412130816
Category : Medical
Languages : en
Pages : 250
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Book Description
Author: Norman M. Kaplan
Publisher: Lippincott Williams & Wilkins
ISBN: 1605475033
Category : Medical
Languages : en
Pages : 480
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Book Description
Listed as the #1 reference book for hypertension by the American Society for Hypertension in 2006, this new edition presents up-to-date, practical, evidence-based recommendations for treatment and prevention of all forms of hypertension.
Author: Ruby Ching-Yu Lin
Publisher:
ISBN:
Category : Gene expression
Languages : en
Pages : 300
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Book Description
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309108675
Category : Social Science
Languages : en
Pages : 429
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Book Description
Biosocial Surveys analyzes the latest research on the increasing number of multipurpose household surveys that collect biological data along with the more familiar interviewerâ€"respondent information. This book serves as a follow-up to the 2003 volume, Cells and Surveys: Should Biological Measures Be Included in Social Science Research? and asks these questions: What have the social sciences, especially demography, learned from those efforts and the greater interdisciplinary communication that has resulted from them? Which biological or genetic information has proven most useful to researchers? How can better models be developed to help integrate biological and social science information in ways that can broaden scientific understanding? This volume contains a collection of 17 papers by distinguished experts in demography, biology, economics, epidemiology, and survey methodology. It is an invaluable sourcebook for social and behavioral science researchers who are working with biosocial data.
