Molecular and Biotechnological Advancements in Hypericum Species PDF Download
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Author: Gregory Franklin
Publisher: Frontiers Media SA
ISBN: 2889451178
Category :
Languages : en
Pages : 161
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Book Description
Hypericum is an important genus of the family Hypericaceae and includes almost 500 species of herbs, shrubs and trees. Being the home for many important bioactive compounds, these species have a long traditional value as medicinal plants. Currently, several species of this genus have been used in ailments as knowledge-based medicine in many countries. In the recent past, several pharmacological studies have been performed using crude extracts to evaluate the traditional knowledge. Results of those studies have revealed that Hypericum extract exert multiple pharmacological properties including antidepressant, antimicrobial, antitumor and wound healing effects. Phytochemical analyses revealed that these species produce a broad spectrum of valuable compounds, mainly naphthodianthrones (hypericin and pseudohypericin), phloroglucinols (hyperforin and adhyperforin), flavonoids (hyperoside, rutin and quercitrin), benzophenones/xanthones (garcinol and gambogic acid), and essential oils. Noticeably, Hypericum perforatum extracts have been used to treat mild to moderate depression from ancient to present times and the antidepressant efficacy of Hypericum extracts has been attributed to its hyperforin content, which is known to inhibit the re-uptake of aminergic transmitters such as serotonin and noradrenaline into synaptic nerve endings. Neurodegenerative diseases and inflammatory responses are also linked with Reactive Oxygen Species (ROS) production. A wide range of flavonoids present in Hypericum extracts, namely, rutin, quercetin, and quercitrin exhibit antioxidant/free radical scavenging activity. Hypericin, beside hyperforin, is the active molecule responsible for the antitumor ability of Hypericumextracts and is seen as a potent candidate to treat brain tumor. Recent attempts of using hypericin in patients with recurrent malignant brain tumors showed promising results. Collectively, Hypericum species contain multiple bioactive constituents, suggesting their potential to occupy a huge portion of the phytomedicine market. Today, studies on medicinal plants are rapidly increasing because of the search for new active molecules, and for the improvement in the production of plants and molecules for the herbal pharmaceutical industries. In the post genomic era, application of molecular biology and genomic tools revolutionized our understanding of major biosynthetic pathways, phytochemistry and pharmacology of Hypericum species and individual compounds. This special issue mainly focuses on the recent advancements made in the understanding of biosynthetic pathways, application of biotechnology, molecular biology, genomics, pharmacology and related areas.
Author: Gregory Franklin
Publisher: Frontiers Media SA
ISBN: 2889451178
Category :
Languages : en
Pages : 161
Get Book Here
Book Description
Hypericum is an important genus of the family Hypericaceae and includes almost 500 species of herbs, shrubs and trees. Being the home for many important bioactive compounds, these species have a long traditional value as medicinal plants. Currently, several species of this genus have been used in ailments as knowledge-based medicine in many countries. In the recent past, several pharmacological studies have been performed using crude extracts to evaluate the traditional knowledge. Results of those studies have revealed that Hypericum extract exert multiple pharmacological properties including antidepressant, antimicrobial, antitumor and wound healing effects. Phytochemical analyses revealed that these species produce a broad spectrum of valuable compounds, mainly naphthodianthrones (hypericin and pseudohypericin), phloroglucinols (hyperforin and adhyperforin), flavonoids (hyperoside, rutin and quercitrin), benzophenones/xanthones (garcinol and gambogic acid), and essential oils. Noticeably, Hypericum perforatum extracts have been used to treat mild to moderate depression from ancient to present times and the antidepressant efficacy of Hypericum extracts has been attributed to its hyperforin content, which is known to inhibit the re-uptake of aminergic transmitters such as serotonin and noradrenaline into synaptic nerve endings. Neurodegenerative diseases and inflammatory responses are also linked with Reactive Oxygen Species (ROS) production. A wide range of flavonoids present in Hypericum extracts, namely, rutin, quercetin, and quercitrin exhibit antioxidant/free radical scavenging activity. Hypericin, beside hyperforin, is the active molecule responsible for the antitumor ability of Hypericumextracts and is seen as a potent candidate to treat brain tumor. Recent attempts of using hypericin in patients with recurrent malignant brain tumors showed promising results. Collectively, Hypericum species contain multiple bioactive constituents, suggesting their potential to occupy a huge portion of the phytomedicine market. Today, studies on medicinal plants are rapidly increasing because of the search for new active molecules, and for the improvement in the production of plants and molecules for the herbal pharmaceutical industries. In the post genomic era, application of molecular biology and genomic tools revolutionized our understanding of major biosynthetic pathways, phytochemistry and pharmacology of Hypericum species and individual compounds. This special issue mainly focuses on the recent advancements made in the understanding of biosynthetic pathways, application of biotechnology, molecular biology, genomics, pharmacology and related areas.
Author: Joginder Singh Panwar
Publisher: Elsevier
ISBN: 0128225556
Category : Technology & Engineering
Languages : en
Pages : 246
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Book Description
New and Future Developments in Microbial Biotechnology and Bioengineering: Recent Advances in Application of Fungi and Fungal Metabolites: Applications in Healthcare presents an account of recent development and applied aspects of fungi and its metabolites in the healthcare sector. Chapters are written by eminent researchers, emphasizing the incredible role of fungi and its metabolites in the field of medicine. This book offers reference material to all mycologists working on the exploration and usage of medicinal aspects of fungi and fungal metabolites. - Introduces the aspects and advances of fungi and fungal metabolites in healthcare - Includes a description of traditional uses and modern practices on how to harness the potential of fungi and its metabolites in healthcare applications - Provides details surrounding the use of fungi and its metabolites in medical purposes - Describes potential manifold prospects of fungi and fungal metabolites
Author: Suresh Kumar Gahlawat
Publisher: Springer
ISBN: 9811047324
Category : Science
Languages : en
Pages : 394
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Book Description
This book presents an overview of the latest advances and developments in plant biotechnology. The respective chapters explore emerging areas of plant biotechnology such as RNAi technology, fermentation technology, genetic engineering, nanoparticles and their applications, climate resilient crops, bio-films, bio-plastic, bio-remediation, flavonoids, antioxidants etc. All chapters were written by respected experts and address the latest developments in plant biotechnology that are of industrial importance, especially with regard to crop yields and post-harvest strategies. As such, the book offers a valuable guide for students, educators and researchers in all disciplines of the life sciences, agricultural sciences, medicine, and biotechnology at universities, research institutions and biotechnology companies.
Author: Harikesh Bahadur Singh
Publisher: Elsevier
ISBN: 0323860001
Category : Technology & Engineering
Languages : en
Pages : 392
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Book Description
This book provides a comprehensive overview of different agriculturally important microorganisms and their role as plant biostimulants. Arbuscular Mycorrhizal Fungi, Trichoderma, Cyanobacteria, Endophytes, and Plant growth promoting rhizobacteria have the potential to promote plant growth, disease management, nutrient acquisition, stress alleviation, and soil health management. Presenting an all-inclusive collection of information, this book will be important for students, academicians, researchers working in the field of sustainable agriculture, microbial technology, and biochemical engineers. It will also be of use for policymakers in the area of food security and sustainable agriculture. - Introduces new microorganisms as plant biostimulants. - Describes potential mechanisms of plant–microbe interaction for stress alleviation and crop improvement. - Provides information about different microbial formulations (consortium) and their application to the alleviation of different abiotic stresses (salt, drought, nutrient deficiency, heavy metal, etc.) in plants. - Discusses about psychrophilic microbes, endophytic microbes, and total plant microbiome and their uses as biostimulants for improving plant health.
Author: Jay Shankar Singh
Publisher: Elsevier
ISBN: 0128182598
Category : Technology & Engineering
Languages : en
Pages : 388
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Book Description
New and Future Developments in Microbial Biotechnology and Bioengineering: Microbes in Soil, Crop and Environmental Sustainability reviews the exploitation of microbial biodiversity in soil with respect to nutrient-use efficiency, also discussing the improvement and maintenance of certain physical and chemical conditions in soil that can provide economic and environmental benefits toward agricultural sustainability. The utilization of microbes ranges from applications in biotechnology, marginal land restoration, the formulation of microbial inoculants, the enhancement of crop productivity, and the mitigation of global warming gases. Finally, various uses for microbial resources in crop disease management, bioenergy production, and income based on microbial cultivation are explored. - Highlights the developments and achievements of microbial resources and their role in the sustainable management of soil fertility and agriculture productivity - Outlines the role of microbial resource and biotechnology in sustainability to industry, agriculture, forest and management of environment - Provides up-to-date information on the application of microbial resources and the role of biotechnology to meet the ever increasing demand of food, soil and plant productivity management - Outlines enhancement in productivity through interventions of microbial bio-agents and eco-friendly technology
Author: Vijai G. Gupta
Publisher: Elsevier
ISBN: 0444635041
Category : Medical
Languages : en
Pages : 378
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Book Description
New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Secondary Metabolites Biochemistry and Applications examines the areas of biotechnology and chemical engineering, covering aspects of plants, bacteria and machines, and using microbes as factories. The book is aimed at undergraduates, post-graduates and researchers studying microbial secondary metabolites, and is an invaluable reference source for biochemical engineers working in biotechnology, manipulating microbes, and developing new uses for bacteria and fungi. The applications of secondary metabolites in biotechnology, pharmaceuticals, diagnostics and medical device development are also extensively covered. The book integrates the aforementioned frontline branches into an interdisciplinary research work to satisfy those working in biotechnology, chemical engineering, alternative fuel development, diagnostics and pharmaceuticals. Chapters related to important research work on applications of microbial secondary metabolites are written by specialists in the various disciplines from the international community.
Author: Mohd Sayeed Akhtar
Publisher: Springer Nature
ISBN: 9811374384
Category : Science
Languages : en
Pages : 341
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Book Description
Natural bioactive compounds have become an integral part of plant-microbe interactions geared toward adaptation to environmental changes. They regulate symbiosis, induce seed germination, and manifest allelopathic effects, i.e., they inhibit the growth of competing plant species in their vicinity. In addition, the use of natural bioactive compounds and their products is considered to be suitable and safe in e.g. alternative medicine. Thus, there is an unprecedented need to meet the increasing demand for plant secondary metabolites in the flavor and fragrance, food, and pharmaceutical industries. However, it is difficult to obtain a constant quantity of compounds from the cultivated plants, as their yield fluctuates due to several factors including genotypic variations, the geography, edaphic conditions, harvesting and processing methods. Yet familiarity with these substances and the exploration of various approaches could open new avenues in their production. This book describes the basis of bioactive plant compounds, their mechanisms and molecular actions with regard to various human diseases, and their applications in the drug, cosmetic and herbal industries. Accordingly, it offers a valuable resource for students, educators, researchers, and healthcare experts involved in agronomy, ecology, crop science, molecular biology, stress physiology, and natural products.
Author: Judit Hohmann
Publisher: Frontiers Media SA
ISBN: 2889458903
Category :
Languages : en
Pages : 356
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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: Ahmed M. Abdel Azeem
Publisher: Academic Press
ISBN: 032399315X
Category : Science
Languages : en
Pages : 466
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Book Description
Endophytic Fungi: The Full Story of the Untapped Treasure covers the developments in endophytic fungal research from beginning to the end by the eminent researchers involved in the field. It sheds light on the endophytic fungal current research, challenges, and future possibilities, the trending recent topics in the plant-fungal endophytes' biodynamics for sustainable development of bioproducts and its applications are supported in large-scale biosynthesis of industrially and pharmaceutical important biomolecules.Endophytic Fungi: The Full Story of the Untapped Treasure highlights the bioprospecting and applied aspects of endophytic fungal communities from diverse hosts and discusses the practical applications of such endophytes in detail. It also reviews recent strategies on alternative sustainable sources of medicines such as secondary metabolites of fungi instead of over collection of plants under prohibiting of biodiversity conventions. The uniqueness of this book is the inclusion of updated bioinformatics-based strategies and its importance in bioactive molecules produced by endophytic fungi. The book addresses one of the most eminent issues in this field: how to translate the potential that endophytic fungi hold in stable practical application. - Covers major concepts of plant-fungi interaction, biodiversity of endophytic fungi from diverse and biotechnological applications for sustainable development - Is extensively illustrated and clearly written, using easy-to-understand language, sharing the latest developments and potential of fungal products for various applications - Sheds light on the endophytic fungal current research, challenges, and future possibilities
Author: Avinash P. Ingle
Publisher: John Wiley & Sons
ISBN: 1119745853
Category : Science
Languages : en
Pages : 378
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Book Description
Discover the role of nanotechnology in promoting plant growth and protection through the management of microbial pathogens In Nanotechnology in Plant Growth Promotion and Protection, distinguished researcher and author Dr. Avinash P. Ingle delivers a rigorous and insightful collection of some of the latest developments in nanotechnology particularly related to plant growth promotion and protection. The book focuses broadly on the role played by nanotechnology in growth promotion of plants and their protection through the management of different microbial pathogens. You’ll learn about a wide variety of topics, including the role of nanomaterials in sustainable agriculture, how nano-fertilizers behave as soil feed, and the dual role of nanoparticles in plant growth promotion and phytopathogen management. You’ll also discover why nanotechnology has the potential to revolutionize the current agricultural landscape through the development of nano-based products, like plant growth promoters, nano-fertilizers, nano-pesticides, and nano-insecticides. Find out why nano-based products promise to be a cost-effective, economically viable, and eco-friendly approach to tackling some of the most intractable problems in agriculture today. You’ll also benefit from the inclusion of: A thorough introduction to the prospects and impacts of using nanotechnology to promote the growth of plants and control plant diseases An exploration of the effects of titanium dioxide nanomaterials on plant growth and the emerging applications of zinc-based nanoparticles in plant growth promotion Practical discussions of nano-fertilizer in enhancing the production potentials of crops and the potential applications of nanotechnology in plant nutrition and protection for sustainable agriculture A concise treatment of nanotechnology in seed science and soil feed Toxicological concerns of nanomaterials used in agriculture Perfect for undergraduate, graduate, and research students of nanotechnology, agriculture, plant science, plant physiology, and crops, Nanotechnology in Plant Growth Promotion and Protection will also earn a place in the libraries of professors and researchers in these areas, as well as regulators and policymakers.
