Molecular advances and applications of machine learning in understanding autism and comorbid psychiatric disorders

Molecular advances and applications of machine learning in understanding autism and comorbid psychiatric disorders PDF Author: Salam Salloum-Asfar
Publisher: Frontiers Media SA
ISBN: 2832529941
Category : Science
Languages : en
Pages : 255

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Book Description

Molecular advances and applications of machine learning in understanding autism and comorbid psychiatric disorders

Molecular advances and applications of machine learning in understanding autism and comorbid psychiatric disorders PDF Author: Salam Salloum-Asfar
Publisher: Frontiers Media SA
ISBN: 2832529941
Category : Science
Languages : en
Pages : 255

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Book Description


Advances in Molecular Pathology, E-Book 2020

Advances in Molecular Pathology, E-Book 2020 PDF Author: Gregory J. Tsongalis
Publisher: Elsevier Health Sciences
ISBN: 032372227X
Category : Medical
Languages : en
Pages : 257

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Book Description
This issue of Advances in Molecular Pathology will provide a comprehensive review of the most current practices, trends, and developments in the field of Molecular Pathology. Publishing on an annual basis, the volume will be divided into 7 sections: Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid tumors, and Identity/HLA. Led by Dr. Gregory Tsongalis of Dartmouth University, a team of experienced pathologists from institutions across the country oversee annual topic and expert author selection.

Key Topics in Psychological Methods

Key Topics in Psychological Methods PDF Author:
Publisher: Springer Nature
ISBN: 3031199227
Category : Electronic books
Languages : en
Pages : 141

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Book Description
This volume features cutting-edge and impactful articles from across Springer's diverse journals publishing program. In this curated collection, our editorial team has brought together highly-cited and downloaded articles on the topic of Psychological Methods into one single resource. Moreover, this book enables readers to review a broad spectrum of quality research on a specialized topic, which we hope facilitates interdisciplinary and critical discussions of the topic at hand. As part of the Key Topics in Behavioral Sciences book series, this volume aims to serve as a quick reference for readers when writing or researching new topics or subject areas. Other topics in the series will include Psychological Research Methods, Health and Behavior, Industrial and Organizational Psychology, Sports Psychology, and Consumer Behavior. In the first section of the volume, articles focus on such topics as Artificial Intelligence, Cultural Learning, Human Evolution, Human-Computer Interaction, Referential Triangle, Social Interaction, Differences, Diversity, Evolution, Genetics, Populations, and Race. Next, the second section features research on Double Dialogicality, Generalization, Qualitative Research, Single Case, Data Analysis, Data Screening, Insufficient Effort Responding, Research Design, Research Methods, and Survey Research. Lastly in the final section of this collection, Data Snooping, Harking, Publication Bias, Simulation, Open Science, Philosophy Of Science, Questionable Research Practices, Research Ethics, Content-Analysis, Dictionary Analysis, Natural Language Processing, Structural Topic Modeling, Text Analysis, Thematic Analysis, and Topic Modeling are discussed.

Personalized Psychiatry

Personalized Psychiatry PDF Author: Bernhard Baune
Publisher: Academic Press
ISBN: 0128131772
Category : Medical
Languages : en
Pages : 594

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Book Description
Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. - Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics - Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry - Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

Genomic Prediction of Complex Traits

Genomic Prediction of Complex Traits PDF Author: Nourollah Ahmadi
Publisher: Springer Nature
ISBN: 1071622056
Category : Science
Languages : en
Pages : 651

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Book Description
This volume explores the conceptual framework and the practical issues related to genomic prediction of complex traits in human medicine and in animal and plant breeding. The book is organized into five parts. Part One reminds molecular genetics approaches intending to predict phenotypic variations. Part Two presents the principles of genomic prediction of complex traits, and reviews factors that affect its reliability. Part Three describes genomic prediction methods, including machine-learning approaches, accounting for different degree of biological complexity, and reviews the associated computer-packages. Part Four reports on emerging trends such as phenomic prediction and incorporation into genomic prediction models of “omics” data and crop growth models. Part Five is dedicated to lessons learned from cases studies in the fields of human health and animal and plant breeding, and to methods for analysis of the economic effectiveness of genomic prediction. Written in the highly successful Methods in Molecular Biology series format, the book provides theoretical bases and practical guidelines for an informed decision making of practitioners and identifies pertinent routes for further methodological researches. Cutting-edge and thorough, Complex Trait Predictions: Methods and Protocols is a valuable resource for scientists and researchers who are interested in learning more about this important and developing field. Chapters 3, 9, 13, 14, and 21 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Future Work in Clinical Child and Adolescent Psychology

Future Work in Clinical Child and Adolescent Psychology PDF Author: Mitchell J. Prinstein
Publisher: Routledge
ISBN: 1351741535
Category : Psychology
Languages : en
Pages : 445

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Book Description
Preeminent clinical child and adolescent psychological scientists offer an agenda for future research in this compendium of thought pieces. On a wide range of topics including ADHD, depression, self-injury, emotion regulation, conduct problems, addictions, clinical assessment and therapy, and many more, scientists review the current state of the literature and offer specific recommendations for what investigators next need to tackle to reduce mental illness among youth. Chapters include a discussion of theories and methods in clinical child and adolescent psychology, current funding priorities, and the intersection of traditional clinical psychology research with the burgeoning field of psychological neuroscience. This book is an essential resource for classes on clinical child and adolescent psychopathology and treatment. It also provides a unique guide for undergraduate and early graduate students who are determining how to start their research careers in the field. All of the chapters in this book were originally published as articles in the Journal of Clinical Child and Adolescent Psychology.

Computational Intelligence for Machine Learning and Healthcare Informatics

Computational Intelligence for Machine Learning and Healthcare Informatics PDF Author: Rajshree Srivastava
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110648199
Category : Computers
Languages : en
Pages : 348

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Book Description
This book presents a variety of techniques designed to enhance and empower multi-disciplinary and multi-institutional machine learning research in healthcare informatics. It is intended to provide a unique compendium of current and emerging machine learning paradigms for healthcare informatics, reflecting the diversity, complexity, and depth and breadth of this multi-disciplinary area.

Neurobiology of Brain Disorders

Neurobiology of Brain Disorders PDF Author: Michael J. Zigmond
Publisher: Academic Press
ISBN: 0323898254
Category : Medical
Languages : en
Pages : 1136

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Book Description
Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders, Second Edition provides basic scientists a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases. Topics include developmental, autoimmune, central, and peripheral neurodegeneration, infectious diseases, and diseases of higher function. Organized by individual disorder, each chapter includes coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. This volume reflects progress in the field since publication of the first edition, with fully updated chapters, and new chapters on isolation, aging, global diseases, vascular diseases, and toxic/metabolic disease. New disorder coverage includes fibromyalgia, chronic fatigue, Restless Legs Syndrome, myasthenia gravis, and more. - Links basic, translational and clinical research on disorders of the nervous system - Covers a vast array of neurological and psychiatric disorders, including Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson's, Huntington's, Alzheimer's, OCD, PTSD, schizophrenia, depression and pain - Features new chapters on the effects of aging and isolation on brain health - Expands coverage on disorders, including new chapters on fibromyalgia, chronic fatigue, and restless legs syndrome - Features in-text summary points, special feature boxes and research questions

Autism Spectrum Disorders

Autism Spectrum Disorders PDF Author: Andreas M. Grabrucker
Publisher:
ISBN:
Category :
Languages : en
Pages : 117

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Book Description
Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.

Molecular Neuropathology

Molecular Neuropathology PDF Author: Gareth W. Roberts
Publisher: Cambridge University Press
ISBN: 9780521425582
Category : Medical
Languages : en
Pages : 204

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Book Description
This volume provides an introduction to the essential techniques required for studying the molecular biology of brain disease. The approaches and strategies for investigations of gene structure and regulation are described with reference to the molecular genetics of prion and Alzheimer's disease. The effects of aberrant gene regulation can also be examined at the protein level by immunocytochemistry and autoradiography. Improved understanding of basic biology has resulted in new approaches to animal models using transgenic techniques and new therapeutic approaches. The volume is structured to illustrate all these approaches and demonstrate the practice and promise of molecular neuropathology.