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Author: Alexander Meisels
Publisher:
ISBN: 9780891895442
Category : Cervix uteri
Languages : en
Pages : 415
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Book Description
Modern Uterine Cytopathology: Moving to the Molecular Smear sets out to be the reference guide that bridges gaps between cytomorphology, molecular biology, and molecular technologies in the diagnostic cytology service. Increasingly, conventional cytology intersects with new technologies based on the link of cervical cancer and human papillomaviruses (HPV). Dr. Meisels and his co-authors/contributors build upon their decades of experience, providing heavily imaged chapters devoted to cytomorphology of infection and benign changes, squamous intraepithelial lesions, glandular lesions, hormonal cytology, and rare lesions of the uterus. Most chapters in Modern Uterine Cytopathology offer practical, working understandings of new and emerging approaches to diagnosis and prevention: prevention of uterine cancers, epidemiology, human papillomaviruses, cervical carcinogenesis, biomarkers for screening, HPV vaccines, LBC imagers and screeners, and technical considerations for molecular and serologic diagnosis. Expert contributors from both North America and Europe bring an international perspective to the evolving practice of cytopathology in a molecular age.
Author: Alexander Meisels
Publisher:
ISBN: 9780891895442
Category : Cervix uteri
Languages : en
Pages : 415
Get Book Here
Book Description
Modern Uterine Cytopathology: Moving to the Molecular Smear sets out to be the reference guide that bridges gaps between cytomorphology, molecular biology, and molecular technologies in the diagnostic cytology service. Increasingly, conventional cytology intersects with new technologies based on the link of cervical cancer and human papillomaviruses (HPV). Dr. Meisels and his co-authors/contributors build upon their decades of experience, providing heavily imaged chapters devoted to cytomorphology of infection and benign changes, squamous intraepithelial lesions, glandular lesions, hormonal cytology, and rare lesions of the uterus. Most chapters in Modern Uterine Cytopathology offer practical, working understandings of new and emerging approaches to diagnosis and prevention: prevention of uterine cancers, epidemiology, human papillomaviruses, cervical carcinogenesis, biomarkers for screening, HPV vaccines, LBC imagers and screeners, and technical considerations for molecular and serologic diagnosis. Expert contributors from both North America and Europe bring an international perspective to the evolving practice of cytopathology in a molecular age.
Author: Matías Jiménez-Ayala
Publisher: Karger Medical and Scientific Publishers
ISBN: 380559464X
Category : Medical
Languages : en
Pages : 124
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Book Description
This outstanding monograph presents a detailed description of cytopathological lesions of the female genital tract. Twelve international experts in the cytopathology of glandular lesions cover the complete spectrum of this challenging subject. Genital glandular lesions, both benign and malignant, are an appealing field of cytopathology. Malignant lesions of the endocervix and endometrium are becoming more common all over the world, compared to squamous cell carcinoma. In situ and invasive endocervical adenocarcinoma, endometrial adenocarcinoma and endometrial hyperplasias are presented in this book. Additionally ovarian lesions focusing data obtained from detailed intraoperative studies and other areas of the genital tract, such as the vulva and fallopian tube, which are less known and thus have seen fewer publications, are also shown. The impact of the Bethesda System, as well as basic and ancillary techniques in the study of glandular lesions complete the monograph. This book will be of great use to cytopathologists, pathologists and cytotechnologists and to students of these specialities as it deals with the most common areas of their daily work.
Author: W. Glenn McCluggage
Publisher: Springer
ISBN: 1447122100
Category : Medical
Languages : en
Pages : 194
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Book Description
This book provides a comprehensive account of the cellular pathology of glandular lesions and uncommon neoplasms of the cervix and places these in a contemporary clinical context. The book features comprehensive, detailed descriptions and a consistent approach to each tumor or tumor-like condition with clear color illustrations. Cytological/histological correlation is emphasised and diagnostic pitfalls are highlighted. Cellular Pathology of Glandular Lesions and Uncommon Neoplasms of the Cervix is aimed at both trainee and consultant pathologists.
Author: Yasuo Hirai
Publisher: Springer Nature
ISBN: 981165011X
Category : Medical
Languages : en
Pages : 268
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Book Description
This book describes a standardized method for classifying and reporting invasive endometrial malignancies via direct endometrial sampling. Featuring a wealth of color illustrations, it provides specific diagnostic categories and cytomorphologic criteria to promote uniform and reliable diagnoses. It also describes the history of directly sampled endometrial cytology, reviews the sampling techniques and algorithmic approach, discusses specimen adequacy, and outlines challenges for the future. The Yokohama System for Reporting Endometrial Cytology – Definitions, Criteria and Explanatory Notes offers a valuable resource for researchers at clinical cytopathological laboratories around the world whose work involves gynecological cytology, oncology, pathology, and cytopathology. It will also appeal to researchers in the fields of cytotechnology, basic science, pathology and related industries, medical residents and clinicians.
Author: Leopold G. Koss
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 224
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Book Description
This volume addresses the essentials of cytopathology of the female genital tract. Histology and modern diagnostic techniques are discussed as well.
Author: Franz Anton Iklé
Publisher:
ISBN: 9789627140016
Category : Cancer
Languages : de
Pages : 477
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Book Description
Includes bibliographical references and index.
Author: John A. Maksem
Publisher: Springer
ISBN: 9780387899091
Category : Medical
Languages : en
Pages : 220
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Book Description
As compared with cytology’s use in other organ systems, direct cytological examination of the endometrium is not a widely practiced diagnostic procedure. This is an anomaly, because the endometrium is exceedingly available for cytological sampling, cytological sampling is comparably simple to perform, and, from the patient’s perspective, it is a gentle procedure as compared to other methods of specimen attainment. Over the years, as we personally gained more and more experience with specimen acquisition, processing and interpretation, we have come to look upon endometrial cytology as an effective method for ensuring endometrial normalcy and discovering and diagnosing malignant and premalignant states. In comparing endometrial cytology to endometrial biopsy, we have found that, in samples obtained by individuals experienced in specimen collection, cytology outperforms outpatient biopsy with regard to the patient’s tolerance of the procedure, adequacy of sampling among postmenopausal women, and detection of occult neoplasms. By devising a highly effective technical strategy to ensure the simultaneous creation of cell blocks and cytological samples from a single collection (that is detailed in the technical appendix of this work), we have moved endometrial brush collection into an arena of significance equaling—indeed exceeding—other methods of specimen collection and interpretation. Cytology, even in the absence of cell blocks, performs equally as well as biopsy in detecting outspoken hyperplasia or carcinoma. If nothing else, by reliably identifying benign, normal endometrial states, it serves to exclude more than 70% of women from unnecessary follow up testing with a high degree of confidence. Because brush sampling of the endometrium is limited to a depth of 1.5 to 2 mm, the method is not definitive for the detection of endometrial polyps, fibroids, stromal tumors, or tumors of the uterine wall musculature. However, endometrial cytology is useful for detecting benign estrogen-excess states such as disordered proliferation and various degrees of benign hyperplasia, for separating these states from frankly neoplastic states such as EIN and cancer, but not for subclassifying benign hyperplastic states in the absence of cell block preparations. When endometrial brushing with liquid fixation is used in conjunction with other techniques such as immunohistochemistry, concomitant biopsy or, more practically, hysteroscopy or sonohysterography, endometrial benignancy can be assured with a very high level of confidence (> 99%); indeed, manufacturing concomitant cell blocks of endometrial tissue fragments and using immunohistochemistry in selected cases significantly enhances the diagnostic specificity of the technique. In a woman with a patent cervix, endometrial brushing successfully collects material, even from late postmenopausal atrophic endometrium. It allows for the detection of serious diseases such as endometrial intraepithelial carcinoma under conditions where suction biopsy might miss or otherwise obviate the diagnosis. This work focuses on the background, collection technique, and reliability of endometrial cytology; it then overviews diagnostic criteria and diagnostic pitfalls encountered in the day-to-day practice of the art. Since endometrial cytology interpretation relies on intuiting tissue patterns from cytology preparations, a great deal of time is spent on cytohistological correlations and, where effective as part of a diagnostic strategy, on ancillary immunohistochemical staining. The discussion moves from normal states of the endometrium, through otherwise benign changes induced by an altered hormonal milieu or surface irritants, into neoplastic premalignant and malignant endometrial conditions. Finally, fixative and slide preparation techniques, that we deem as expeditious while serving to get the most information out of an endometrial cytology collection, are discussed in detail for the benefit of those who wish to recapitulate our work in their own practice.
Author: Robert A. Soslow
Publisher: Cambridge University Press
ISBN: 110737605X
Category : Medical
Languages : en
Pages : 877
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Book Description
Part of the Cambridge Illustrated Surgical Pathology series, this book provides a comprehensive account of the experienced gynecologic pathologists' diagnostic approach to uterine pathology. Discussion is built around major pathologic entities in the uterus and cervix while highlighting the diverse and complex spectrum of alterations encountered in daily practice. Emphasizing clear description, diagnostic algorithms and problem solving, the book's primary goal is to lay the foundation for diagnostic accuracy, reproducibility, and relevance. It also dispels common misconceptions and encourages an intelligent and thoughtful approach to diagnostic problems using all the tools available to the modern physician. The book is richly illustrated, with more than 700 color photomicrographs, all of which are also found in downloadable format on the accompanying CD-ROM.
Author: Paolo Gattuso
Publisher: Cambridge University Press
ISBN: 1107040299
Category : Medical
Languages : en
Pages : 695
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Book Description
This updated edition remains the essential text for pathologists seeking to make accurate diagnoses from the vast number of differentials.
Author: Ritu Nayar
Publisher: Springer
ISBN: 3319110748
Category : Medical
Languages : en
Pages : 342
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Book Description
This book offers clear, up-to-date guidance on how to report cytologic findings in cervical, vaginal and anal samples in accordance with the 2014 Bethesda System Update. The new edition has been expanded and revised to take into account the advances and experience of the past decade. A new chapter has been added, the terminology and text have been updated, and various terminological and morphologic questions have been clarified. In addition, new images are included that reflect the experience gained with liquid-based cytology since the publication of the last edition in 2004. Among more than 300 images, some represent classic examples of an entity while others illustrate interpretative dilemmas, borderline cytomorphologic features or mimics of epithelial abnormalities. The Bethesda System for Reporting Cervical Cytology, with its user-friendly format, is a “must have” for pathologists, cytopathologists, pathology residents, cytotechnologists, and clinicians.
