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Author: Paolo Quadrelli
Publisher: Elsevier
ISBN: 0128152745
Category : Science
Languages : en
Pages : 354
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Book Description
Modern Applications of Cycloaddition Chemistry examines this area of organic chemistry, with special attention paid to cycloadditions in synthetic and mechanistic applications in modern organic chemistry. While many books dedicated to cycloaddition reactions deal with the synthesis of heterocycles, general applications, specific applications in natural product synthesis, and the use of a class of organic compounds, this work sheds new light on pericyclic reactions by demonstrating how these valuable tools elegantly solve synthetic and mechanistic problems. The work examines how pericyclic reactions have been extensively applied to different chemistry areas, such as chemical biology, biological processes, catalyzed cycloaddition reactions, and more. This work will be useful for organic chemists who deal with organic chemistry, medicinal chemistry, agrochemistry and material chemistry. - Provides details on the synthesis of antiviral and anticancer compounds, marking the key role of unconventional catalyzed cycloaddition reactions for preparing new derivatives in a unique reaction pathway that is scalable in industrial processes - Contains the most up-to-date review of the use of pericyclic reactions in drug delivery - Includes the enzyme-catalyzed processes involving cycloaddition reactions for different targets, demonstrating that cycloaddition is more common in nature than expected - Features new applications for cycloadditions in material chemistry and provides a general view of the most recent results in the area
Author: Paolo Quadrelli
Publisher: Elsevier
ISBN: 0128152745
Category : Science
Languages : en
Pages : 354
Get Book Here
Book Description
Modern Applications of Cycloaddition Chemistry examines this area of organic chemistry, with special attention paid to cycloadditions in synthetic and mechanistic applications in modern organic chemistry. While many books dedicated to cycloaddition reactions deal with the synthesis of heterocycles, general applications, specific applications in natural product synthesis, and the use of a class of organic compounds, this work sheds new light on pericyclic reactions by demonstrating how these valuable tools elegantly solve synthetic and mechanistic problems. The work examines how pericyclic reactions have been extensively applied to different chemistry areas, such as chemical biology, biological processes, catalyzed cycloaddition reactions, and more. This work will be useful for organic chemists who deal with organic chemistry, medicinal chemistry, agrochemistry and material chemistry. - Provides details on the synthesis of antiviral and anticancer compounds, marking the key role of unconventional catalyzed cycloaddition reactions for preparing new derivatives in a unique reaction pathway that is scalable in industrial processes - Contains the most up-to-date review of the use of pericyclic reactions in drug delivery - Includes the enzyme-catalyzed processes involving cycloaddition reactions for different targets, demonstrating that cycloaddition is more common in nature than expected - Features new applications for cycloadditions in material chemistry and provides a general view of the most recent results in the area
Author: Shu Kobayashi
Publisher: John Wiley & Sons
ISBN: 9783527301591
Category : Science
Languages : en
Pages : 354
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Book Description
During the miners' strike in the 1980s, a worker is killed in the striking coalfields of Wales. Some months later, a government minister thought to be connected with the death is also shot. Lewis Redfern—once a radical but now a political analyst and journalist—pursues the sniper, a lonely hunt that leads him through an imbroglio of civil service leaks to a secret organization: a source of insurrection far more powerful than anyone could have suspected known as the Volunteers. In this fast-paced narrative of espionage and intrigue, Redfern, through his obsessive pursuit of justice, finally encounters the truth about himself as the novel discusses the conflict between moral choice and political loyalty.
Author: Eric F.V. Scriven
Publisher: Academic Press
ISBN: 032390128X
Category : Science
Languages : en
Pages : 332
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Book Description
Advances in Heterocyclic Chemistry, Volume 136 is the latest release in this definitive series in the field of heterocyclic chemistry, one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature is used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. - Considered the definitive serial in the field of heterocyclic chemistry - Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists - Provides the latest comprehensive reviews written by established authorities in the field - Combines descriptive synthetic chemistry and mechanistic insights to enhance understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds
Author: W. Carruthers
Publisher: Elsevier
ISBN: 008091232X
Category : Science
Languages : en
Pages : 382
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Book Description
Demonstrates the wide scope of cycloaddition reactions, including the Diels-Alder reaction, the ene reaction, 1,3-dipolar cycloadditions and [2+2] cycloadditions in organic synthesis. The author, a leading exponent of the subject, illustrates the ways in which they can be employed in the synthesis of a wide range of carbocyclic and heterocyclic compounds, including a variety of natural products of various types. Special attention is given to intramolecular reactions, which often provide a rapid and efficient route to polycyclic compounds, and to the stereochemistry of the reactions, including recent and developing work on enantioselective synthesis.
Author: Takashiro Akitsu
Publisher: BoD – Books on Demand
ISBN: 1839689536
Category : Science
Languages : en
Pages : 198
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Book Description
Chirality is a concept related not only to organic chemistry but also to each field of natural science. Awareness of hierarchy is important for universal and comprehensive understanding. As such, this book examines myriad subjects related to chirality in chemistry and interdisciplinary applications. In contrast to the previous book, this new book about chirality includes contributions from authors in many fields of natural science, providing a wider overview. The book’s focus is chirality and organic chemistry, including synthesis and reactions.
Author: Singh, Ajeet
Publisher: IGI Global
ISBN: 1668451301
Category : Science
Languages : en
Pages : 754
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Book Description
A great deal of interest has been generated recently in the isolation, characterization, and biological activity of phytochemicals. Phytochemicals have the potential to enhance pharmaceuticals and drug discovery. As such, there is an urgent need for current research in the global scope of phytochemicals including the chemical and physical characteristics, analytical procedures, biological activity, safety, and industrial applications. The Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery examines the applications of bioactive molecules from a health perspective, examining the pharmacological aspects of medicinal plants, the phytochemical and biological activities of different natural products, and ethnobotany and medicinal properties. Moreover, it presents a novel dietary approach for human disease management. Covering topics such as computer-aided drug design, government regulation, and medicinal plant taxonomy, this major reference work is beneficial to pharmacists, medical practitioners, phytologists, hospital administrators, government officials, faculty and students of higher education, librarians, researchers, and academicians.
Author: Peter J. Stang
Publisher: John Wiley & Sons
ISBN: 3527615261
Category : Science
Languages : en
Pages : 527
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Book Description
This comprehensive handbook presents the full potential of modern acetylene chemistry, from organic synthesis through materials science to bioorganic chemistry. K. Houk, H. Hopf, P. Stang, K. M. Nicholas, N. Schore, M. Regitz, K. C. Nicolaou, R. Gleiter, L. Scott, R. Grubbs, H. Iwamura, J. Moore, and F. Diederich - internationally renowned authors introduce the reader, in a didactically skilful manner, to the state-of-the-art in alkyne chemistry. Emphasis is placed on presenting carefully selected and instructive examples as well as essential references to the original literature. Special benefits: Each chapter is rounded off by useful experimental procedures.
Author: Albert Padwa
Publisher: John Wiley & Sons
ISBN: 0471461369
Category : Science
Languages : en
Pages : 952
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Book Description
Dipolar cycloaddition reactions have found many useful applications in chemistry, particularly with respect to the synthesis of compounds with new chiral centers. Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products updates the popular 1984 edition, featuring the advances made over the past twenty years and focusing on synthetic applications.
Author: Akkattu T. Biju
Publisher: John Wiley & Sons
ISBN: 3527346465
Category : Science
Languages : en
Pages : 530
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Book Description
A groundbreaking book to offer a a comprehensive account of important reactions involving arynes Modern Aryne Chemistry is the first book on the market to offer a conceptual framework to the reactions related to arynes. It also provides a systematic introduction to the cycloaddition reactions, insertion reactions and transition-metal-catalyzed transformations of arynes. The author, a noted expert on the topic, highlights a novel strategy for carbon-carbon and carbon-heteroatom bond construction using arynes. The book reveiws the recent use of aryne chemistry for the development of new multicomponent reactions. New advances in this area has shown rapid emergence of a new class of reactions classified under rearrangement reactions. The author also includes information on aryne methods that have been employed for the synthesis of several natural products. The simplicity and sophistication of the synthetic strategy using arynes can serve as a springboard for organic chemists to explore new possibilities and imagine applications of the concept of arynes. This important book: Presents a one-of-kind comprehensive guide to arynes reactions Offers a proven approach to the synthesis of natural product and polymers Reviews the most recent developments in the carbon-carbon and carbon-heteroatom bond-forming reactions involving arynes Written for organic, pharmaceutical, medicinal, natural products, and catalytic Chemists, Modern Aryne Chemistry offers a comprehensive review of the fundamentals of reactions related to arynes and the most recent developments in the field.
Author: Jianbo Wang
Publisher: John Wiley & Sons
ISBN: 3527829156
Category : Science
Languages : en
Pages : 450
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Book Description
Presents an up-to-date overview of the rapidly growing field of carbene transformations Carbene transformations have had an enormous impact on catalysis and organometallic chemistry. With the growth of transition metal-catalyzed carbene transformations in recent decades, carbene transformations are today an important compound class in organic synthesis as well as in the pharmaceutical and agrochemical industries. Edited by leading experts in the field, Transition Metal-Catalyzed Carbene Transformations is a thorough summary of the most recent advances in the rapidly expanding research area. This authoritative volume covers different reaction types such as ring forming reactions and rearrangement reactions, details their conditions and properties, and provides readers with accurate information on a wide range of carbene reactions. Twelve in-depth chapters address topics including carbene C-H bond insertion in alkane functionalization, the application of engineered enzymes in asymmetric carbene transfer, progress in transition-metal-catalyzed cross-coupling using carbene precursors, and more. Throughout the text, the authors highlight novel catalytic systems, transformations, and applications of transition-metal-catalyzed carbene transfer. Highlights the dynamic nature of the field of transition-metal-catalyzed carbene transformations Summarizes the catalytic radical approach for selective carbene cyclopropanation, high enantioselectivity in X-H insertions, and bio-inspired carbene transformations Introduces chiral N,N'-dioxide and chiral guanidine-based catalysts and different transformations with gold catalysis Discusses approaches in cycloaddition reactions with metal carbenes and polymerization with carbene transformations Outlines multicomponent reactions through gem-difunctionalization and transition-metal-catalyzed cross-coupling using carbene precursors Transition Metal-Catalyzed Carbene Transformations is essential reading for all chemists involved in organometallics, including organic and inorganic chemists, catalytic chemists, and chemists working in industry.
