Models of Scientific Development and the Case of Nuclear Magnetic Resonance

Models of Scientific Development and the Case of Nuclear Magnetic Resonance PDF Author: Henk Zandvoort
Publisher: Springer Science & Business Media
ISBN: 940094764X
Category : Science
Languages : en
Pages : 318

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Book Description
From the nineteen sixties onwards a branch of philosophy of science has come to development, called history-oriented philosophy of science. This development constitutes a reaction on the then prevailing logical empiricist conception of scientific knowledge. The latter was increasingly seen as suffering from insurmountable internal problems, like e. g. the problems with the particular "observational-theoretical distinction" on which it drew. In addition the logical empiricists' general approach was increasingly criticized for two external shortcomings. Firstly, the examples of scientific knowledge that the logical empiricists were focusing on were con sidered as too simplistic to be informative on the nature of real life science. Secondly, it was felt that the attention of these philosophers of science was restricted to the static aspects of scientific knowledge, while neglecting its developmental aspects. History-oriented philosophy of science has taken up the challenge implicit in the latter two criticisms, i. e. to develop accounts of science that would be more adequate for understanding the development 1 of real life science. One of the more successful products of this branch of philosophy of science is Lakatos's theory of scientific development, sometimes called the "methodology of scientific research programmes". This theory conceives science as consisting of so called research program mes developing in time, and competing with each other over the issue which one generates the best explan~tions of the phenomena that they address.

Models of Scientific Development and the Case of Nuclear Magnetic Resonance

Models of Scientific Development and the Case of Nuclear Magnetic Resonance PDF Author: Henk Zandvoort
Publisher:
ISBN: 9789400947658
Category :
Languages : en
Pages : 324

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Book Description


Biological NMR Spectroscopy

Biological NMR Spectroscopy PDF Author: John L. Markley
Publisher: Oxford University Press
ISBN: 0195094689
Category : Medical
Languages : en
Pages : 375

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Book Description
This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.

Experimental Approaches of NMR Spectroscopy

Experimental Approaches of NMR Spectroscopy PDF Author: The Nuclear Magnetic Resonance Society of Japan
Publisher: Springer
ISBN: 9811059667
Category : Science
Languages : en
Pages : 634

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Book Description
This book describes the advanced developments in methodology and applications of NMR spectroscopy to life science and materials science. Experts who are leaders in the development of new methods and applications of life and material sciences have contributed an exciting range of topics that cover recent advances in structural determination of biological and material molecules, dynamic aspects of biological and material molecules, and development of novel NMR techniques, including resolution and sensitivity enhancement. First, this book particularly emphasizes the experimental details for new researchers to use NMR spectroscopy and pick up the potentials of NMR spectroscopy. Second, the book is designed for those who are involved in either developing the technique or expanding the NMR application fields by applying them to specific samples. Third, the Nuclear Magnetic Resonance Society of Japan has organized this book not only for NMR members of Japan but also for readers worldwide who are interested in using NMR spectroscopy extensively.

Compact NMR

Compact NMR PDF Author: Bernhard Blümich
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110374587
Category : Technology & Engineering
Languages : en
Pages : 305

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Book Description
The goal of this book is to provide an introduction to the practical use of mobile NMR at a level as basic as the operation of a smart phone. Each description follows the same didactic pattern: introduction, basic theory, pulse sequences and parameters, beginners-level measurements, advanced-level measurements, and data processing. Nuclear Magnetic Resonance (NMR) spectroscopy is the most popular method for chemists to analyze molecular structures while Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic tool for medical doctors that provides high-contrast images of biological tissue depicting the brain function and the beating heart. In both applications large super-conducting magnets are employed which magnetize atomic nuclei of an object positioned inside the magnet. Their circulating motion is interrogated by radio-frequency waves. Depending on the operating mode, the frequency spectrum provides the chemist with molecular information, the medical doctor with anatomic images, while the materials scientist is interested in NMR relaxation parameters, which scale with material properties and determine the contrast in magnetic resonance images. Recent advances in magnet technology led to a variety of small permanent magnets, by which NMR spectra, images, and relaxation parameters can be measured with mobile and low-cost instruments.

Applications of NMR Spectroscopy

Applications of NMR Spectroscopy PDF Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 168108287X
Category : Science
Languages : en
Pages : 289

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Book Description
Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture. The fifth volume of the series features several reviews focusing on NMR spectroscopic techniques for identifying natural and synthetic compounds (polymer and peptide characterization, GABA in tinnitus affected mice), medical diagnosis and therapy (gliomas) and food analysis. The spectroscopic methods highlighted in this volume include high resolution proton magnetic resonance spectroscopy and solid state NMR.

A Model-Theoretic Realist Interpretation of Science

A Model-Theoretic Realist Interpretation of Science PDF Author: E.B. Ruttkamp
Publisher: Springer Science & Business Media
ISBN: 9401705836
Category : Science
Languages : en
Pages : 236

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Book Description
In this book Emma Ruttkamp demonstrates the power of the full-blown employment of the model-theoretic paradigm in the philosophy of science. Within this paradigm she gives an account of sciences as process and product. She expounds the "received statement" and the "non-statement" views of science, and shows how the model-theoretic approach resolves the spurious tension between these views. In this endeavour she also engages the views of a number of contemporary philosophers of science with affinity to model theory. This text can be read by specialists working in philosophy of science or formal semantics, by logicians working on the structure of theories, and by students in philosophy of science - this text offers a thorough introduction to non-statement accounts of sciences as well as a discussion of the traditional statement account of science.

Fire Debris Analysis

Fire Debris Analysis PDF Author: Eric Stauffer
Publisher: Academic Press
ISBN: 0080556264
Category : Law
Languages : en
Pages : 683

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Book Description
The study of fire debris analysis is vital to the function of all fire investigations, and, as such, Fire Debris Analysis is an essential resource for fire investigators. The present methods of analysis include the use of gas chromatography and gas chromatography-mass spectrometry, techniques which are well established and used by crime laboratories throughout the world. However, despite their universality, this is the first comprehensive resource that addresses their application to fire debris analysis.Fire Debris Analysis covers topics such as the physics and chemistry of fire and liquid fuels, the interpretation of data obtained from fire debris, and the future of the subject. Its cutting-edge material and experienced author team distinguishes this book as a quality reference that should be on the shelves of all crime laboratories. - Serves as a comprehensive guide to the science of fire debris analysis - Presents both basic and advanced concepts in an easily readable, logical sequence - Includes a full-color insert with figures that illustrate key concepts discussed in the text

Metabonomics

Metabonomics PDF Author: Jacob T. Bjerrum
Publisher: Humana
ISBN: 9781493923762
Category : Science
Languages : en
Pages : 0

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Book Description
This volume on metabonomics provides detailed information on the procedures involved in nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GS-MS), liquid chromatography-mass spectrometry (LC-MS), and capillary electrophoresis-mass spectrometry (CE-MS). Chapters focus on technologies and chemometrics, generation of metabonomics data, extraction of meaningful information from data, drug development, toxicology, diagnostics, and describing metabonomics as an essential part of systems biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Introduction to Spectroscopy

Introduction to Spectroscopy PDF Author: Donald L. Pavia
Publisher:
ISBN: 9789865632021
Category : Organic compounds
Languages : en
Pages : 764

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Book Description