Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves PDF full book. Access full book title Modeling Human Atrial Patho-Electrophysiology from Ion Channels to ECG - Substrates, Pharmacology, Vulnerability, and P-Waves by Loewe, Axel. Download full books in PDF and EPUB format.
Author: Loewe, Axel
Publisher: KIT Scientific Publishing
ISBN: 3731505282
Category :
Languages : en
Pages : 344
Get Book
Book Description
Author: Loewe, Axel
Publisher: KIT Scientific Publishing
ISBN: 3731505282
Category :
Languages : en
Pages : 344
Get Book
Book Description
Author: Axel Loewe
Publisher:
ISBN: 9781013283871
Category : Medical
Languages : en
Pages : 334
Get Book
Book Description
Half of the patients suffering from atrial fibrillation (AF) cannot be treated adequately, today. This book presents multi-scale computational methods to advance our understanding of patho-mechanisms, to improve the diagnosis of patients harboring an arrhythmogenic substrate, and to tailor therapy. The modeling pipeline ranges from ion channels on the subcellular level up to the ECG on the body surface. The tailored therapeutic approaches carry the potential to reduce the burden of AF. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Author: Javier Saiz
Publisher: Frontiers Media SA
ISBN: 2889662195
Category : Science
Languages : en
Pages : 248
Get Book
Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: Nagel, Claudia
Publisher: KIT Scientific Publishing
ISBN: 3731512815
Category :
Languages : en
Pages : 280
Get Book
Book Description
An early detection and diagnosis of atrial fibrillation sets the course for timely intervention to prevent potentially occurring comorbidities. Electrocardiogram data resulting from electrophysiological cohort modeling and simulation can be a valuable data resource for improving automated atrial fibrillation risk stratification with machine learning techniques and thus, reduces the risk of stroke in affected patients.
Author: Pollnow, Stefan
Publisher: KIT Scientific Publishing
ISBN: 3731508869
Category :
Languages : en
Pages : 296
Get Book
Book Description
Author: Sánchez Arciniegas, Jorge Patricio
Publisher: KIT Scientific Publishing
ISBN: 3731511703
Category : Medical
Languages : en
Pages : 162
Get Book
Book Description
The atrial substrate undergoes electrical and structural remodeling during atrial fibrillation. Detailed multiscale models were used to study the effect of structural remodeling induced at the cellular and tissue levels. Simulated electrograms were used to train a machine-learning algorithm to characterize the substrate. Also, wave propagation direction was tracked from unannotated electrograms. In conclusion, in silico experiments provide insight into electrograms' information of the substrate.
Author: Mathias Wilhelms
Publisher: KIT Scientific Publishing
ISBN: 3731500450
Category : Technology & Engineering
Languages : en
Pages : 206
Get Book
Book Description
Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface.AbstractEnglisch = Multiscale modeling of cardiac electrophysiology helps to better understand the underlying mechanisms of atrial fibrillation, acute cardiac ischemia and pharmacological treatment. For this purpose, measurement data reflecting these conditions have to be integrated into models of cardiac electrophysiology. Several methods for this model adaptation are introduced in this thesis. The resulting effects are investigated in multiscale simulations ranging from the ion channel up to the body surface.
Author: Daniel C. Sigg
Publisher: Springer Science & Business Media
ISBN: 1441966587
Category : Medical
Languages : en
Pages : 490
Get Book
Book Description
Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.
Author: Gunnar Seemann
Publisher:
ISBN: 9783937300665
Category :
Languages : en
Pages : 233
Get Book
Book Description
Author: Jose Jalife
Publisher: Wiley-Blackwell
ISBN: 1444316958
Category : Medical
Languages : en
Pages : 360
Get Book
Book Description
This book translates fundamental knowledge in basic cardiac electrophysiology from the bench to the bedside. Revised and updated for its second edition, the text offers new coverage of the molecular mechanisms of ion channel behavior and its regulation, complex arrhythmias, and the broadening roles of devices and ablation. Clear, straightforward explanations are illustrated by plentiful diagrams to make the material accessible to the non-specialist.
