Mitochondria in Obesity and Type 2 Diabetes

Mitochondria in Obesity and Type 2 Diabetes PDF Author: Beatrice Morio
Publisher: Academic Press
ISBN: 0128117524
Category : Medical
Languages : en
Pages : 460

Get Book Here

Book Description
Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers.

Mitochondria in Obesity and Type 2 Diabetes

Mitochondria in Obesity and Type 2 Diabetes PDF Author: Beatrice Morio
Publisher: Academic Press
ISBN: 0128117524
Category : Medical
Languages : en
Pages : 460

Get Book Here

Book Description
Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers.

Mitochondrial Dysfunction

Mitochondrial Dysfunction PDF Author: Lawrence H. Lash
Publisher: Elsevier
ISBN: 1483218619
Category : Science
Languages : en
Pages : 527

Get Book Here

Book Description
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Mitochondrial Gene Expression

Mitochondrial Gene Expression PDF Author:
Publisher:
ISBN: 9781071608340
Category : Gene expression
Languages : en
Pages :

Get Book Here

Book Description


Metabolic Cardiomyopathy

Metabolic Cardiomyopathy PDF Author: H. Böhles
Publisher: CRC Press
ISBN: 9783887631048
Category : Medical
Languages : en
Pages : 188

Get Book Here

Book Description
During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.

Diabetes Associated with Single Gene Defects and Chromosomal Abnormalities

Diabetes Associated with Single Gene Defects and Chromosomal Abnormalities PDF Author: Fabrizio Barbetti
Publisher:
ISBN: 9783318060249
Category : Chromosome abnormalities
Languages : en
Pages : 0

Get Book Here

Book Description
This volume, written by renowned experts, provides complete coverage of the main genetic conditions associated with diabetes. Divided into five sections, it offers insights into genetic defects involving the pancreatic beta cell, extreme insulin resistance, ciliopathies, obesity and glucose metabolism, chromosomal defects, and other genetic conditions associated with increased susceptibility to diabetes. Other topics include the various subtypes of monogenic diabetes, such as the neonatal form and the Wolfram syndrome, as well as chromosomal defects leading to complex conditions affiliated with diabetes, like Trisomy 21 or Prader-Willi syndrome. There are also chapters dedicated to the poorly explored relationships between metabolism and neurodegenerative disorders like Friedreich's ataxia and muscular dystrophy. This book is a reference for every pediatric and adult endocrinologist and diabetologist, even experienced ones, with an interest in the intricacies and protean aspects of disorders of glucose metabolism secondary to genetic diseases.

Adipose Tissue in Health and Disease

Adipose Tissue in Health and Disease PDF Author: Todd Leff
Publisher: John Wiley & Sons
ISBN: 9783527629534
Category : Science
Languages : en
Pages : 530

Get Book Here

Book Description
This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.

Diabetes Mellitus in Children

Diabetes Mellitus in Children PDF Author: Mark A. Sperling
Publisher:
ISBN: 9781416027539
Category : Children
Languages : en
Pages : 0

Get Book Here

Book Description


Obesity and Lipotoxicity

Obesity and Lipotoxicity PDF Author: Ayse Basak Engin
Publisher: Springer
ISBN: 331948382X
Category : Science
Languages : en
Pages : 618

Get Book Here

Book Description
Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.

Diabetes Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment

Diabetes Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment PDF Author: Enzo Bonora
Publisher: Springer
ISBN: 9783319450148
Category : Medical
Languages : en
Pages : 0

Get Book Here

Book Description
This book provides the reader with comprehensive information on the epidemiology, etiology, pathogenesis, pathophysiology, clinical features, prevention, and treatment of diabetes with the aim of empowering health care providers in their daily battle against the disease. Diabetes has been identified by WHO and the United Nations as a medical emergency because of the increase in its global prevalence, which may reach one billion in three to four decades if the trend remains unchanged. Despite improved care that is helping to prolong life, diabetes impacts substantially on the quality of life of those affected and kills or disables several million people each year. The disease is systemic because all organs, tissues, and cells suffer in the presence of hyperglycemia and are damaged by the diabetic milieu. Unfortunately, most patients with diabetes will consequently experience chronic diabetic complications. This book, combining basic science with a practical clinical orientation, will be of value for all physicians and nurses who care for patients with diabetes.

Fat Chance

Fat Chance PDF Author: Robert Lustig
Publisher:
ISBN: 9780007514144
Category : Health & Fitness
Languages : en
Pages : 0

Get Book Here

Book Description
Documenting the science and the politics that has led to the pandemic of metabolic syndrome - whose symptoms include obesity, diabetes and heart disease - Robert Lustig exposes for the first time how changes in the food industry and in our wider environment have affected our collective metabolisms and waistlines.