Magnesium in the Central Nervous System

Magnesium in the Central Nervous System PDF Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354

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Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Magnesium in the Central Nervous System

Magnesium in the Central Nervous System PDF Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354

Get Book

Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Migraine in Women

Migraine in Women PDF Author: Elizabeth Loder
Publisher: PMPH-USA
ISBN: 9781550091809
Category : Health & Fitness
Languages : en
Pages : 212

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Book Description
Fifteen specialists serve as chapter authors, covering sex hormones and genetics, as well as the social, cultural, psychiatric, and psychological factors that contribute to headache disorders. Their approach is evidence-based, but where there are gaps in research, the authors provide advice based on expert consensus and clinical experience. Each chapter opens with a case report that synthesizes the chapter's treatment recommendations, as well as key points listing the chapter's contents. The main body of the chapter features an introductory overview, a closing summary, tables, and an extensive list of suggestive reading.

ABC of Headache

ABC of Headache PDF Author: Anne MacGregor
Publisher: John Wiley & Sons
ISBN: 1118682009
Category : Medical
Languages : en
Pages : 88

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Book Description
In its different presentations, headache is one of the most commonsymptoms seen by family practitioners. The difficulty is indiagnosing the cause of the headache so that the appropriatetreatment is provided, or if referral to a specialist is therecommended course of action. The ABC of Headache helps with this dilemma and guidesthe healthcare professional to look for the possible causes ofpresenting symptoms. Based on real case histories, each chapterguides the reader from symptoms through to diagnosis andmanagement. This new ABC is a highly illustrated, informative, andpractical source of knowledge. With links to further informationand resources, it is a valuable text for healthcare professionalsat all levels of practice and training.

Case Studies in Pain Management

Case Studies in Pain Management PDF Author: Alan David Kaye
Publisher: Cambridge University Press
ISBN: 1107682894
Category : Medical
Languages : en
Pages : 547

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Book Description
Edited by internationally recognized pain experts, this book offers 73 clinically relevant cases, accompanied by discussion in a question-and-answer format.

Headache and Migraine Biology and Management

Headache and Migraine Biology and Management PDF Author: Seymour Diamond
Publisher: Academic Press
ISBN: 0128011629
Category : Science
Languages : en
Pages : 334

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Book Description
There are two crucial issues in the treatment and management of headache patients: More than 50% of individuals experiencing headache have only been treated symptomatically, with no appropriate diagnosis established; and history and neurologic examination are essential to establishing a diagnosis, and thus selecting appropriate therapy. Headache and Migraine Biology and Management is a practical text that addresses these issues, featuring contributions from expert clinical authors. The book covers in detail topics including chronic and episodic migraine, post-traumatic headache, sinus headache, cluster headache, tension headache, and others. Chapters are also dedicated to treatment subjects, including psychiatric and psychological approaches, medication overuse, inpatient treatment, and pediatric issues. This book is an ideal resource for researchers and clinicians, uniting practical discussion of headache biology, current ideas on etiology, future research, and genetic significance and breakthroughs. This resource is useful to those who want to understand headache biology, treat and manage symptoms, and for those performing research in the headache field. A practical discussion of headache biology, current ideas on etiology, future research, and genetic significance and breakthroughs Features chapters from leading physicians and researchers in headache medicine Full-color text that includes both an overview of multiple disciplines and discusses the measures that can be used to treat headaches

Drug-Induced Headache

Drug-Induced Headache PDF Author: Hans-Christoph Diener
Publisher: Springer Science & Business Media
ISBN: 3642733271
Category : Medical
Languages : en
Pages : 174

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Book Description
M. WILKINSON Patients with frequent or daily headaches pose a very difficult problem for the physician who has to treat them, particularly as many patients think that there should be a medicine or medicines which give them instant relief. In the search for the compound which would meet this very natural desire, many drugs have been manufactured and the temptation for the physician is either to increase the dose of a drug which seems to be, at any rate, partially effective, or to add one or more drugs to those which the patient is already taking. Although there have been some references to the dangers of overdosage of drugs for migraine in the past, it was not until relatively recently that it was recognized that drugs given for the relief of headache, if taken injudiciously, may themselves cause headache. The first drugs to be implicated in this way were ergotamine and phenazone. In the case of ergotamine tartrate, the dangers of ergotism were well known as this was a disorder which had been known and written about for many years. In the treatment of headache, fully blown ergotism is rare and in recent years has usually been due to self-medication in doses much greater than those prescribed although there are a few recorded cases where toxic amounts have been given.

Pathophysiology of Headaches

Pathophysiology of Headaches PDF Author: Messoud Ashina
Publisher: Springer
ISBN: 3319156217
Category : Medical
Languages : en
Pages : 272

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Book Description
This book provides a detailed overview of the current state of knowledge regarding the pathophysiology of both primary headaches – migraine, tension-type headache (TTH), and cluster headache – and the very important and frequent type of secondary headache, medication overuse headache (MOH). After an introductory chapter describing relevant neuroanatomy and vascular anatomy, the evidence gained from animal models regarding the pathophysiology of migraine and the other primary headaches is reviewed. Knowledge of the genetic component in the different types of headache is then examined with reference to recent evidence, for example regarding the implication of the trigeminovascular system and cortical spreading depression in migraine. Detailed information is provided on insights into primary headaches from imaging studies, including functional magnetic resonance imaging and positron emission tomography and on their neurophysiology and biochemistry. A further series of important chapters describe present knowledge of the pathophysiology of each specific type of headache and consider future directions. Written by acknowledged experts in their fields from Europe and the United States, clinicians and students will find Pathophysiology of Headaches to be an excellent source of up-to-date information on why patients experience headaches. In addition, it will be of value for pain researchers investigating the underlying mechanisms of headache.

Pituitary Adenylate Cyclase-Activating Polypeptide

Pituitary Adenylate Cyclase-Activating Polypeptide PDF Author: Hubert Vaudry
Publisher: Springer Science & Business Media
ISBN: 1461502438
Category : Medical
Languages : en
Pages : 406

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Book Description
Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Migraine Surgery

Migraine Surgery PDF Author: Bahman Guyuron
Publisher: Thieme
ISBN: 1626237727
Category : Medical
Languages : en
Pages : 351

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Book Description
The definitive guide on migraine surgery from the world's leading authority An estimated 11.7% of the U.S. population or nearly 38 million adults and children suffer from migraine headaches. A severe and highly debilitating type of headache, migraine is the third most common and eighth most disabling disease in the world. People who suffer from migraines often experience neurological symptoms such as nausea and visual disturbances. Despite optimal preventive and abortive pharmacologic treatment, as many as one-third of migraine patients experience refractory headaches and persistent symptoms. Migraine Surgery by world-renowned plastic surgeon Bahman Guyuron reflects significant knowledge gleaned from 17 years of migraine research, pioneering development of nerve decompression surgery, and 2,500 migraine surgery procedures. With contributions from top neurologists and plastic surgeons, this state-of-the-art book is the only one on the market dedicated to the surgical treatment of migraines. The book begins with a brief history of migraines, followed by a concise overview covering clinical presentation, imaging, abortive, and preventive treatments such as over-the-counter and prescription medications, neurotoxin injections, peripheral nerve blocks, and neuromodulation. Key Highlights Discussion of migraine trigger points including impacted anatomy, detection methods, and trigger point deactivation surgery Surgical treatment of frontal, temporal, rhinogenic, occipital, auriculotemporal, lesser occipital, and nummular migraines including postoperative care and complications Superb illustrations provide visual insights on compressions points, trigger sites, nerves, and the surgical treatment of headaches Extensive high-quality videos posted in the Thieme Media Center delineate life-altering surgical approaches This one-of-a-kind book is the ultimate guide to headache surgery and a must have for resident and veteran plastic surgeons alike. Neurologists and neurosurgeons will also benefit from reading this succinct yet masterful resource.

Prehospital Care of Neurologic Emergencies

Prehospital Care of Neurologic Emergencies PDF Author: Todd Crocco
Publisher: Cambridge University Press
ISBN: 1139993607
Category : Medical
Languages : en
Pages : 213

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Book Description
Prehospital Care of Neurologic Emergencies is a reliable and definitive resource for emergency medical services personnel at multiple levels: physicians, paramedics, nurses and others who encounter these critically ill patients. This focused and succinct book addresses the management of a wide range of neurologic emergencies, including traumatic brain injuries, spinal cord injuries, strokes, and seizures. In these emergencies time is critical, and the simply presented, straightforward format of the patient care and management recommendations help readers to treat patients rapidly and confidently. Each chapter follows a standard format that includes an overview of each neurologic emergency, important background, key challenges, and areas requiring future investigation. This book is unlikely to be placed on your bookshelf; instead, you will keep it nearby for times when you face life-threatening neurologic emergencies. When seconds count, this book has the answers.