Author: T. M. S. Chang
Publisher: Springer Science & Business Media
ISBN: 1461251826
Category : Technology & Engineering
Languages : en
Pages : 304

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Author: Max Donbrow
Publisher: CRC Press
ISBN: 1000083535
Category : Medical
Languages : en
Pages : 554

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First published in 1992: This book provides a comprehensive look at the design and production of microcapsules, microspheres, and nanoparticles. It discusses the diverse aspects and skills that must be mastered to prepare and test products that will work correctly and be clinically acceptable for human or animal use.

Author: Emmanuel C. Opara
Publisher: Humana
ISBN: 9781493963621
Category : Science
Languages : en
Pages : 0

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This volume provides a unique forum to review cell microencapsulation in a broad sense by exploring various cell types that have been encapsulated for different purposes, different approaches and devices used for microencapsulation, the biomaterials used in cell microencapsulation, the challenges to the technology, and the current status of its application in different clinical situations. This book is divided in five sections: Section I is an introductory part that discusses historical developments of the technology and its current challenges, as well as the various applications of cell microencapsulation; Section II discusses the main approaches and devices currently used in cell microencapsulation; Section III presents an overview of the various polymeric materials currently in use for cell microencapsulation and the enabling technologies to either monitor or enhance encapsulated cell function; Section IV gives specific examples of the methods used to encapsulate various cell types; and Section V provides an overview of the different clinical situations in which cell microencapsulation has been applied. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and practical, Cell Microencapsulation: Methods and Protocols is a valuable reference for researchers, engineers, clinicians, and other healthcare professionals, as well as food technologists who will find detailed descriptions of methods for the microencapsulation of specific cell types and their current of potential clinical and industrial applications. This volume also includes detailed information about the design and manufacture of different devices including large-scale production devices for use in cell microencapsulation.

Author: Jan E. Vandegaer
Publisher: Springer Science & Business Media
ISBN: 1468407392
Category : Medical
Languages : en
Pages : 183

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of McGill University of Montreal, Canada, who talks about artifi cial cells prepared from semipermeable microcapsules. Also illustrative of this method is a contribution on microencapsulated pesticides by C. B. Desavigny and E. E. Ivy of Pennwalt Corporation. Another method of polymerization in situ is micro encapsulation by vapor deposition, the subject of W. M. Jayne of Union Carbide Corporation. The more mechanical methods of microencapsulation are represented by two techniques, one involving a fluidized bed the other involving mainly a centrifugal method. The fluidized bed method is covered in a paper by H. Hall and T. M. Hinkes of the Wisconsin Alumini Research Foundation. The centrifugal and other related methods are treated by Mr. J. E. Goodwin and Mr. Sommerville of the Southwest Research Institute of San Antoni~ Texas. Dr. G. Baxter of Moore Business Forms, studied capsules made by mechanical methods as well as by chemical methods. Mr. Russell G. Arnold of the Bureau of Veteranary Medicine of the Food and Drug Administration draws our attention to the procedures to be used for securing approval of a new animal drug application for the marketing of microencapsulated products. And last but not least, we have a contribution by Mr. G. O. Fanger on "Micro encapsulation a Brief History and Introduction, whose title speaks for itself.

Author: Thomas Ming Swi Chang
Publisher: World Scientific
ISBN: 9812770372
Category : Medical
Languages : en
Pages : 482

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50th anniversary of artificial cells -- Basic principles -- Oxygen carriers based on nanobiotechnology -- A nanobiotechnologic therapeutic that transports oxygen and remove oxygen radicals: for stroke, hemorrhagic shock and related conditions -- Nanotechnology-based artificial red blood cells (RBC's) -- Use of enzyme artificial cells for genetic enzyme defects that increase systemic substrates to toxic levels -- Enzyme artificial cells in substrate-dependent tumors and activation of prodrug -- Artificial cells for cell encapsulation -- Artificial cells containing hepatocytes and/or stem cells in regenerative medicine -- Hemoperfusion in poisoning, kidney failure, liver failure, and immunology -- Perspectives on the future of artificial cells as suggested by past research.

Author: Nedal Abu-Thabit
Publisher: BoD – Books on Demand
ISBN: 1839683481
Category : Science
Languages : en
Pages : 292

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Book Description
Nano- or micro-encapsulation is used in many different fields and industries, including pharmaceuticals, cosmetics, food, and agrochemicals. It offers advantages for various applications, especially drug delivery. Nano-encapsulation can help extend and control the release of drugs as well as increase drug bioavailability and efficacy. It improves the precision of targeted drug delivery and allows for fabricating nano-encapsulated drugs for diagnostic and theranaostic applications. This book covers recent advances in fabricating nano-/micro-capsules using natural carriers for therapeutic and diagnostic drug delivery applications as well as rheology and formulations of micro-emulsions for diverse applications. This book is essential for scientists and researchers with diverse backgrounds in chemistry, engineering, material sciences, pharmaceuticals, and drug delivery.

Author: Parmjit Singh Panesar
Publisher: John Wiley & Sons
ISBN: 1119701236
Category : Technology & Engineering
Languages : en
Pages : 500

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Book Description
In Probiotics, Prebiotics and Synbiotics: Technological Advancements Towards Safety and Industrial Applications, a team of distinguished researchers delivers an insightful exploration of various aspects of functional foods. The book includes information about critical facets of the production of these beneficial compounds, recent technological developments in the field, and their present and future commercial potential. The authors describe their mechanisms of action and their applications in several sectors. Probiotics, Prebiotics and Synbiotics is divided into five parts. A general introduction about these substances begins the book and is followed by discussions of common probiotics, prebiotics, and synbiotics. Finally, a treatment of safety issues and regulatory claims, as well as their market potential, rounds out the resource. Perfect for researchers, industry practitioners, and students working in or studying food processing and food microbiology, Probiotics, Prebiotics and Synbiotics is also an invaluable resource for professionals working in the field of food biotechnology.

Author: Craig Halberstadt
Publisher: Elsevier
ISBN: 0080469043
Category : Science
Languages : en
Pages : 699

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Book Description
There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for many others in trial phases. The long history of cellular transplantation, or the transfer of cells from one organism or region of the body to another, has been revolutionized by advances in stem cell research, as well as developments in gene therapy. Cellular Transplants: From Lab to Clinic provides a thorough foundation of the basic science underpinning this exciting field, expert overviews of the state-of-the-art, and detailed description of clinical success stories to date, as well as insights into the road ahead. As highlighted by this timely and authoritative survey, scale-up technologies and whole organ transplantation are among the hurdles representing the next frontier. The contents are organized into four main sections, with the first covering basic biology, including transplant immunology, the use of immunosuppressive drugs, stem cell biology, and the development of donor animals for transplantation. The next part looks at peripheral and reconstructive applications, followed by a section devoted to transplantation for diseases of the central nervous system. The last part presents efforts to address the key challenges ahead, such as identifying novel transplantable cells and integrating biomaterials and nanotechnology with cell matrices. - Provides detailed description of clinical trials in cell transplantation - Review of current therapeutic approaches - Coverage of the broad range of diseases addressed by cell therapeutics - Discussion of stem cell biology and its role in transplantation

Author: Willem_M. Kühtreiber
Publisher: Springer Science & Business Media
ISBN: 1461215862
Category : Medical
Languages : en
Pages : 457

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The concept of using encapsulation for the immunoprotection of transplanted cells was introduced for the first time in the 1960s. "[Microencapsulated cells] might be protected from destruction and from partici pation in immunological processes, while the enclosing membrane would be permeable to small molecules of specific cellular product which could then enter the general extracellular compartment of the recipient. For instance, encapsulated endocrine cells might survive and maintain an effective supply of hormone." (Chang, Ph. D. Thesis, McGill University, 1965; Chang et aI., Can J Physiol PharmacoI44:115-128, 1966). We asked Connaught Laboratories, Ltd., in Toronto to put this concept into practice. In 1980, Lim and Sun from Connaught Laboratories reported on the successful implantation of poly-I-Iysine-alginate encapsu lated rat islets into a foreign host. [Lim and Sun, Science 210:908-909, 1980]. Now many groups around the world are making tremendous progress in the encapsulation of a multitude of cell types. Kiihtreiber, Lanza, and Chick have invited many cell encapsulation groups from around the world to contribute to this book. The result is a very useful reference book in this rapidly growing area. With so many excellent au thors describing in detail the different areas of cell encapsulation, my role here will be to briefly discuss a few points.

Author: Thomas Ming Swi Chang
Publisher: World Scientific
ISBN: 9814472875
Category : Medical
Languages : en
Pages : 599

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Nanomedicine consists of the use of nanotechnology and nanobiotechnology in medicine. There have been extensive developments in the area of nanomedicine. The scope of this book is first to discuss the origin of nanomedicine. Following this, instead of a general overview of the whole area, 24 chapters on selected topics of important areas are described in detail. Authors are selected from around the world to give a representative and international view of the activities in the area of nanomedicine.