Author: Christoph Wittmann
Publisher: John Wiley & Sons
ISBN: 352734179X
Category : Science
Languages : en
Pages : 789
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Book Description
The latest volume in the Advanced Biotechnology series provides an overview of the main production hosts and platform organisms used today as well as promising future cell factories in a two volume book. Alongside describing tools for genetic and metabolic engineering for strain improvement, the authors also impart topical information on computational tools, safety aspects and industrial-scale production. Following an introduction to general concepts, historical developments and future technologies, the text goes on to cover multi-purpose bacterial cell factories, including those organisms that exploit anaerobic biosynthetic power. Further chapters deal with microbes used for the production of high-value natural compounds and those obtained from alternative raw material sources, concluding with eukaryotic workhorses.
Author: Stephen Van Dien
Publisher: Springer
ISBN: 3319419668
Category : Science
Languages : en
Pages : 124
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Book Description
This volume reviews the current metabolic engineering tools and technologies from a practical point of view, and guides researchers as they overcome challenges at various stages of organism and bioprocess development. Microbes have been engineered to produce a variety of industrial products such as fuels, basic chemicals, fine chemicals, nutritional supplements, and pharmaceutical intermediates, and new tools such as gene synthesis, advanced cloning techniques, ‘omics’ analysis, and mathematical modeling have greatly accelerated the pace of innovation in the field. Written by leading experts in the field from both academia and industry, key topics include synthetic biology, pathway engineering, metabolic flux manipulation, adaptive evolution, and fermentation process scale-up. It is suitable for non-specialists, and is a valuable resource for anyone embarking on the exciting path to harnessing the metabolic potential of microorganisms.
Author: Vijai Singh
Publisher: Academic Press
ISBN: 0128214783
Category : Science
Languages : en
Pages : 490
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Book Description
Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. - Offers basic understanding and a clear picture of various MCFs - Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others - Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications - Highlights the advances, challenges, and future opportunities in designing MCFs
Author: Satinder K. Brar
Publisher: John Wiley & Sons
ISBN: 1119247969
Category : Science
Languages : en
Pages : 352
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Book Description
A comprehensive review of the fundamental molecular mechanisms in fermentation and explores the microbiology of fermentation technology and industrial applications Microbial Sensing in Fermentation presents the fundamental molecular mechanisms involved in the process of fermentation and explores the applied art of microbiology and fermentation technology. The text contains descriptions regarding the extraordinary sensing ability of microorganisms towards small physicochemical changes in their surroundings. The contributors — noted experts in the field — cover a wide range of topics such as microbial metabolism and production (fungi, bacteria, yeast etc); refined and non-refined carbon sources; bioprocessing; microbial synthesis, responses and performance; and biochemical, molecular and extra/intracellular controlling. This resource contains a compilation of literature on biochemical and cellular level mechanisms for microbial controlled production and includes the most significant recent advances in industrial fermentation. The text offers a balanced approach between theory and practical application, and helps readers gain a clear understanding of microbial physiological adaptation during fermentation and its cumulative effect on productivity. This important book: Presents the fundamental molecular mechanisms involved in microbial sensing in relation to fermentation technology Includes information on the significant recent advances in industrial fermentation Contains contributions from a panel of highly-respected experts in their respective fields Offers a resource that will be essential reading for scientists, professionals and researchers from academia and industry with an interest in the biochemistry and microbiology of fermentation technology Written for researchers, graduate and undergraduate students from diverse backgrounds, such as biochemistry and applied microbiology, Microbial Sensing in Fermentation offers a review of the fundamental molecular mechanisms involved in the process of fermentation.
Author: Johann Bauer
Publisher: CRC Press
ISBN: 9780849389184
Category : Science
Languages : en
Pages : 342
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Book Description
This book presents a summary of the application and instrumentation of cell electrophoresis. The method of making cell purification and characterization possible according to the cellular negative surface charge density is discussed, and ideas for future developments are explained. The negative electrostatic forces at cell surfaces provide information about cell-cell interaction, blood vessel sealing, cytokine actions, cell transformation, ion transport phenomena, and other biological phenomena. Recalculations of the physical principles of cell electrophoresis reveal possibilities for removing disruptive factors caused by electrical current, heat, and sedimentation. The introduction of computer technology, the performance of simultaneous two-parameter measurements, and the application of cell-friendly but current-inert buffer systems render the method more reliable and efficient.
Author: Ashok Pandey
Publisher: Elsevier
ISBN: 0444639918
Category : Technology & Engineering
Languages : en
Pages : 480
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Book Description
Current Developments in Biotechnology and Bioengineering: Current Advances in Solid-State Fermentation provides knowledge and information on solid-state fermentation involving the basics of microbiology, biochemistry, molecular biology, genetics and principles of genetic engineering, metabolic engineering and biochemical engineering. This volume of the series is on Solid-State fermentation (SSF), which would cover the basic and applied aspects of SSF processes, including engineering aspects such as design of bioreactors in SSF. The book offers a pool of knowledge on biochemical and microbiological aspects as well as chemical and biological engineering aspects of SSF to provide an integrated knowledge and version to the readers. - Provides state-of-the-art information on basic and fundamental principles of solid-state fermentation - Includes key features for the education and understanding of biotechnology education and R&D, in particular on SSF - Lists fermentation methods for the production of a wide variety of enzymes and metabolites - Provides examples of the various industrial applications of enzymes in solid state fermentation
Author: J. R. Sokatch
Publisher: Academic Press
ISBN: 1483261387
Category : Science
Languages : en
Pages : 456
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Book Description
Bacterial Physiology and Metabolism focuses on research on bacteria, as well as metabolism of carbohydrates, fermentation, and oxidation of acids. The book first offers information on nutrition and growth of bacterial cultures, including requirements for growth, nutritional classification of bacteria, measurement of bacterial growth, and synchronous growth of bacterial cultures. The manuscript then considers the chemical composition of bacteria, oligosaccharide catabolism, and transport of sugars. The publication takes a look at the fermentation of sugars and aerobic metabolism of carbohydrates. Discussions focus on Embden-Meyerhof fermentations, miscellaneous pathways, and hexose, pentose, polyol, and hexuronic acid oxidation. The text also elaborates on oxidation of organic acids, electron transport, oxidation of hydrocarbons, and protein and amino acid catabolism. The text is a dependable reference for readers interested in bacterial physiology and metabolism.
Author: Peter Grunwald
Publisher: CRC Press
ISBN: 9814463892
Category : Medical
Languages : en
Pages : 1201
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Book Description
Biocatalysis has become an essential tool in the chemical industry and is the core of industrial biotechnology, also known as white biotechnology, making use of biocatalysts in terms of enzymes or whole cells in chemical processes as an alternative to chemical catalysts. This shift can be seen in the many areas of daily life where biocatalysts-with
Author: Christoph Wittmann
Publisher: John Wiley & Sons
ISBN: 3527341811
Category : Science
Languages : en
Pages : 642
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Book Description
The latest volume in the Advanced Biotechnology series provides an overview of the main product classes and platform chemicals produced by biotechnological processes today, with applications in the food, healthcare and fine chemical industries. Alongside the production of drugs and flavors as well as amino acids, bio-based monomers and polymers and biofuels, basic insights are also given as to the biotechnological processes yielding such products and how large-scale production may be enabled and improved. Of interest to biotechnologists, bio and chemical engineers, as well as those working in the biotechnological, chemical, and food industries.
Author: Meisam Tabatabaei
Publisher: Springer
ISBN: 3030009858
Category : Technology & Engineering
Languages : en
Pages : 244
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Book Description
This book presents in-depth information on the state of the art of global biodiesel production and investigates its impact on climate change. Subsequently, it comprehensively discusses biodiesel production in terms of production systems (reactor technologies) as well as biodiesel purification and upgrading technologies. Moreover, the book reviews essential parameters in biodiesel production systems as well as major principles of operation, process control, and trouble-shooting in these systems. Conventional and emerging applications of biodiesel by-products with a view to further economize biodiesel production are also scrutinized. Separate chapters are dedicated to economic risk analysis and critical comparison of biodiesel production systems as well as techno-economical aspects of biodiesel plants. The book also thoroughly investigates the important aspects of biodiesel production and combustion by taking advantage of advanced sustainability analysis tools including life cycle assessment (LCA) and exergy techniques. In closing, the application of Omics technologies in biodiesel production is presented and discussed. This book is relevant to anyone with an interest in renewable, more sustainable fuel and energy solutions.
