Medical Applications of Synchrotron Radiation at the National Synchrotron Light Source PDF Download
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Languages : en
Pages : 11
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Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 11
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Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 11
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Book Description
The overriding features of the synchrotron beams which make them applicable to medical research are their extremely high intensity and broadband energy spectrum. Several orders of magnitude separate the smooth, continuous spectrum of the synchrotron from the sharply peaked characteristic emission spectrum of a conventional source. Basically, the high intensity and tunability allow monochromatic beams to be generated at virtually any energy. The standard problem of beam hardening in both medical imaging and therapy is eliminated by the monochromatic beams since the energy spectrum does not change with passage through tissue. The tunable spectrum allows enhancement of images and therapeutic dose by selection of the most effective energy for a given procedure.
Author: Masami Ando
Publisher: Springer Science & Business Media
ISBN: 4431684859
Category : Medical
Languages : en
Pages : 243
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Book Description
Synchrotron radiation has important applications in medical imaging, especially in such areas as intravenous coronary angiography, mammography, bronchography, and monochromatic computed tomography. In medicine, phase contrast imaging is a particularly exciting development, with the potential to become a new X-ray eye in the 21st century. To discuss these and related topics, medical doctors met with physicists and other researchers in Haga, Japan, in August 1997. This volume contains the proceedings of the International Workshop on Medical Applications of Synchrotron Radiation (HAGA 97), where practitioners from the world of medicine could communicate directly with researchers from the world of physics to discuss practical and theoretical aspects of medical imaging with synchrotron radiation. This volume, presenting the outcome of the discussions and presentations in the workshop, is a valuable resource to all who are interested in medical imaging and physics.
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Languages : en
Pages : 15
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Book Description
In the relatively short time that synchrotrons have been available to the scientific community, their characteristic beams of UV and X-ray radiation have been applied to virtually all areas of medical science which use ionizing radiation. The ability to tune intense monochromatic beams over wide energy ranges clearly differentiates these sources from standard clinical and research tools. The tunable spectrum, high intrinsic collimation of the beams, polarization and intensity of the beams make possible in-vitro and in-vivo research and therapeutic programs not otherwise possible. From the beginning of research operation at the National Synchrotron Light Source (NSLS), many programs have been carrying out basic biomedical research. At first, the research was limited to in-vitro programs such as the x-ray microscope, circular dichroism, XAFS, protein crystallography, micro-tomography and fluorescence analysis. Later, as the coronary angiography program made plans to move its experimental phase from SSRL to the NSLS, it became clear that other in-vivo projects could also be carried out at the synchrotron. The development of SMERF (Synchrotron Medical Research Facility) on beamline X17 became the home not only for angiography but also for the MECT (Multiple Energy Computed Tomography) project for cerebral and vascular imaging. The high energy spectrum on X17 is necessary for the MRT (Microplanar Radiation Therapy) experiments. Experience with these programs and the existence of the Medical Programs Group at the NSLS led to the development of a program in synchrotron based mammography. A recent adaptation of the angiography hardware has made it possible to image human lungs (bronchography). Fig. 1 schematically depicts the broad range of active programs at the NSLS.
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Category :
Languages : en
Pages : 26
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Author: Ari Ide-Ektessabi
Publisher: Springer Science & Business Media
ISBN: 3540464271
Category : Science
Languages : en
Pages : 226
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Book Description
This book demonstrates the applications of synchrotron radiation in certain aspects of cell microbiology, specifically non-destructive elemental analyses, chemical-state analyses and imaging (distribution) of the elements within a cell. The basics for understanding and applications of synchrotron radiation are also described to make the contents more easily understood for a wide group of researchers in medical and biological sciences who might not be familiar with the physics of synchrotron radiation.
Author: Herman Winick
Publisher: World Scientific
ISBN: 9789810224240
Category : Science
Languages : en
Pages : 534
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Book Description
Specialists in the technical components of a synchrotron light source are usually well versed in their field and in the associated technical literature. However, with the rapid and continuing growth of synchrotron radiation research, and with new facilities coming online and being authorized for design and construction around the world, there is a need for a reference book that describes the various technical components of a synchrotron light source in a manner that will be useful to those who lack specialized technical background, but who have responsibility for some part of the design, construction, operation or development of such a facility. This would include technicians, engineers and physicists who have technical background in related fields but no specific experience with a synchrotron light source, and also project managers, laboratory directors, and government officials involved with synchrotron light facilities.College level scientific or engineering training or the equivalent experience is assumed and appropriate mathematics is used throughout. However, the basic concepts in each chapter are given in less technical language and a glossary of terms as well as an index will make the book useful for those with less technical training or experience.
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Category :
Languages : en
Pages :
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Book Description
X-ray fluorescence has long been used as a technique for elemental analysis. X-ray fluorescence techniques have a number of features that make them attractive for application to biomedical samples. In the past few years synchrotron radiation x-ray sources have been developed and, because of their properties, their use can improve the sensitivity for trace element analysis by two to three orders of magnitude. Also, synchrotron radiation will make possible an x-ray microprobe with resolution in the micrometer range. The National Synchrotron Light Source (NSLS), a dedicated synchrotron radiation source recently built at Brookhaven National Laboratory, will have a facility for trace element analysis by x-ray fluorescence and will be available to all interested users.
Author: R. Sweet
Publisher: Springer Science & Business Media
ISBN: 1468480413
Category : Technology & Engineering
Languages : en
Pages : 354
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Book Description
The development of synchrotron radiation (SR) as a research tool was driven largely by the needs of materials scientists and solid-state physi cists. However, the availability of SR has extended significantly the capa bility of scientists who study biological structure with radiation. This volume contains some of the results reported at a symposium held at Brookhaven National Laboratory in May 1988 to discuss the application of synchrotron radiation to structural biology. We are grateful for financial support from the u. s. Department of Energy, the National Institutes of Health, Genentech, Inc., Blake Indus tries, Inc., Evans and Sutherland Co., The Upjohn Company, Eli Lilly and Company, Enraf-Nonius Service Corp., and Associated Universities, Inc. We warmly thank Ms. Nancy Siemon for her tireless efforts with correspondence and the manuscripts for this symposium volume. Symposium Committee: Robert M. Sweet, Chair Malcolm S. Capel Benno P. Schoenborn John C. Sutherland Elizabeth C. Theil Stephen W. White Avril D. Woodhead Helen Z. Kondratuk, Coordinator v CONTENTS An Introduction to the Symposium . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 R. M. Sweet SYMPOSIUM LECTURE Developments in X-ray Technology and Their Contribution to Structural Biology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 H. E. Huxley SOME OF THE SYNCHROTRON FACILITIES FOR BIOLOGICAL STRUCTURAL STUDIES MacChess - A Macromolecular Diffraction Resource at the Cornell High Energy Synchrotron Source . . . . . . . . . . . . . . . . . . . 15 W. Schi1dkamp, K. Moffat, B. Batterman, D. Bilderback, T-Y. Teng, A. LeGrand and D. Szebenyi Facilities Available for Biophysics Research at the Stanford Synchrotron Radiation Laboratory. . . . . . . . . . . . . . . . . . . . . 19 R. P."
Author: Giorgio Margaritondo
Publisher:
ISBN: 9780198509318
Category : Science
Languages : en
Pages : 276
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Book Description
This book is structured by two-level presentation including a simple descriptive treatment and slightly more in-depth discussions of specific topics. The first-level treatment covers the notions, terminology and techniques that are required to use a synchrotron facility. The book is therefore an ideal first step for all those beginning to use synchrotron light for their work or are considering it. The treated topics include the basic functioning mechanisms of synchrotrons and free electron lasers a description of sychrotron-based techniques in x-ray imaging and radiology, spectroscopy, microscopy and spectromicroscopy, EXAFS, crystallography and scattering, and microfabrication.
