Advancing Nuclear Medicine Through Innovation

Advancing Nuclear Medicine Through Innovation PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309134153
Category : Medical
Languages : en
Pages : 173

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Book Description
Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Advancing Nuclear Medicine Through Innovation

Advancing Nuclear Medicine Through Innovation PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309134153
Category : Medical
Languages : en
Pages : 173

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Book Description
Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Cyclotron Produced Radionuclides

Cyclotron Produced Radionuclides PDF Author:
Publisher:
ISBN: 9789201002082
Category : Business & Economics
Languages : en
Pages : 0

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Book Description
This book provides a comprehensive treatment of cyclotrons, with a special emphasis on production of radionuclides. Individual sections are devoted to accelerator technology, theoretical aspects of nuclear reactions, the technology behind targetry, techniques for preparation of targets, irradiation of targets under high beam currents, target processing and target recovery. This book will appeal to scientists and technologists interested in translating cyclotron technology into practice, as well as postgraduate students in this field.

Molybdenum-99 for Medical Imaging

Molybdenum-99 for Medical Imaging PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309445310
Category : Medical
Languages : en
Pages : 264

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Book Description
The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.

Radiopharmaceuticals for Positron Emission Tomography - Methodological Aspects

Radiopharmaceuticals for Positron Emission Tomography - Methodological Aspects PDF Author: G. Stöcklin
Publisher: Springer Science & Business Media
ISBN: 9401582041
Category : Medical
Languages : en
Pages : 210

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Book Description
Radiochemical methodology constitutes the most important base for the successful functioning of a PET group in the routine production and development of radiopharmaceuticals. Of the several hundred products which have been labelled with positron emitters during the past two decades about 35 are presently considered to be of major interest. The time for a state-of-the-art review is right, since this field has advanced over the past fifteen years to reach a level where guidelines can now be suggested. Chapters of this book deal with each of the main methodological aspects of the chemistry needed to develop an effective radiopharmaceutical, namely radionuclide production, automation and metabolite analysis. A further chapter on QA/QC is written by a broadly-based expert group and is meant to provide a guideline and a base for future monographs and regulations on major PET radiopharmaceuticals of today. This book will help the increasing numbers of scientists who are now entering the field of PET to appreciate the methodological aspects that are normally addressed by chemists in relation to PET radiopharmaceuticals; it provides many useful practical guidelines and will promote early success in their own endeavours, since these will often necessarily begin by establishing chemical methodology of the kind discussed here.

Handbook of Nuclear Chemistry

Handbook of Nuclear Chemistry PDF Author: Attila Vértes
Publisher: Springer Science & Business Media
ISBN: 9781402013058
Category : Medical
Languages : en
Pages : 422

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Book Description
Impressive in its overall size and scope, this five-volume reference work provides researchers with the tools to push them into the forefront of the latest research. The Handbook covers all of the chemical aspects of nuclear science starting from the physical basics and including such diverse areas as the chemistry of transactinides and exotic atoms as well as radioactive waste management and radiopharmaceutical chemistry relevant to nuclear medicine. The nuclear methods of the investigation of chemical structure also receive ample space and attention. The international team of authors consists of 77 world-renowned experts - nuclear chemists, radiopharmaceutical chemists and physicists - from Austria, Belgium, Germany, Great Britain, Hungary, Holland, Japan, Russia, Sweden, Switzerland and the United States. The Handbook is an invaluable reference for nuclear scientists, biologists, chemists, physicists, physicians practicing nuclear medicine, graduate students and teachers - virtually all who are involved in the chemical and radiopharmaceutical aspects of nuclear science. The Handbook also provides for further reading through its rich selection of references.

Medical Radionuclide Production

Medical Radionuclide Production PDF Author: Syed M. Qaim
Publisher: de Gruyter
ISBN: 9783110601565
Category : SCIENCE
Languages : en
Pages : 0

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Book Description
The work describes the production technology of standard medical radionuclides using reactors and cyclotrons for patient diagnosis and therapy. A special focus lies on the science and technology involved in the development of novel radionuclides for positron emission tomography (PET) and internal targeted radiotherapy. The availability of those radionuclides is opening up new potential in clinical research, especially in neurology, cardiology and oncology. The future perspectives of the developing technology are also discussed.

Cyclotron Produced Radionuclides

Cyclotron Produced Radionuclides PDF Author: International Atomic Energy Agency
Publisher:
ISBN: 9789201069085
Category : Business & Economics
Languages : en
Pages : 266

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Book Description
Application of radioisotopes has shown significant growth in the past decade, and a major factor contributing towards this growth is the availability of a large number of cyclotrons dedicated to the production of radioisotopes for medical applications. Although there are many articles in journals on cyclotrons and their use for radioisotope production, there is no single source of information for beginners on radioisotope production using cyclotrons. This publication attempts to address this deficiency. Its contains chapters on accelerator technology, theoretical considerations of nuclear reactions, the technology behind targetry, techniques on preparation of targets, irradiation of targets under high beam currents, target processing and target recovery.

Medical Applications of Nuclear Physics

Medical Applications of Nuclear Physics PDF Author: K. Bethge
Publisher: Springer Science & Business Media
ISBN: 3662086085
Category : Science
Languages : en
Pages : 216

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Book Description
Methods involving nuclear physics are today finding applications in many disciplines, including important areas of medicine. This book intends to bridge the gap between the many applications in medicine and the underlying basic nuclear physics which needs to be understood by those applying the methods. In addition, those active in nuclear science will gain insight into the manifold applications of their subject. The main topics of the book are: physical foundations, instrumentation, diagnostics (imaging), therapies and radiation safety. The book will appeal to medical doctors active in nuclear medicine as well as to medical physicists.

Isotope Production And Applications In The 21st Century, Proceedings Of The 3rd International Conference On Isotopes

Isotope Production And Applications In The 21st Century, Proceedings Of The 3rd International Conference On Isotopes PDF Author: Nigel R Stevenson
Publisher: World Scientific
ISBN: 9814493724
Category : Science
Languages : en
Pages : 521

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Book Description
The Third International Conference on Isotopes focused on the theme of “Isotope Production and Applications in the 21st Century” and included presentations by several eminent experts in this field. The three central subjects — Isotopes in Medicine, Industry and the Environment — were supplemented by presentations on the latest developments in isotope production and synthesis, research into radiopharmaceuticals, applications in agriculture, analytical applications, radiocarbon dating, AMS and PET. Various views on the future directions for producers and users of isotopes were considered at this multi-disciplinary meeting.

Alternative Radionuclide Production with a Cyclotron

Alternative Radionuclide Production with a Cyclotron PDF Author: IAEA
Publisher: International Atomic Energy Agency
ISBN: 9201032218
Category : Medical
Languages : en
Pages : 102

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Book Description
Cyclotrons are currently used for the preparation of a wide variety of radionuclides that have applications in single photon emission computed tomography (SPECT) and positron emission tomography (PET). Consequently, there is high demand from IAEA Member States for support in the area of radiopharmaceutical production using cyclotron produced radioisotopes. This publication describes the potential radionuclide production routes using cyclotrons in different energy ranges and provides methods for the development of targets and provides details of the chemistry for the separation of radionuclides from target materials. The readership of this publication includes scientists, operators interested in putting this technology into practice, technologists already working with cyclotrons who wish to enhance the utility of existing machines, and managers in the process of setting up radionuclide facilities in their countries. Students working towards higher level degrees in related fields may also benefit from this publication.