Mechanisms of Environmental Carcinogenesis: Multistep models of carcinogenesis

Mechanisms of Environmental Carcinogenesis: Multistep models of carcinogenesis PDF Author:
Publisher:
ISBN:
Category : Carcinogenesis
Languages : en
Pages : 154

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Mechanisms of Environmental Carcinogenesis: Multistep models of carcinogenesis

Mechanisms of Environmental Carcinogenesis: Multistep models of carcinogenesis PDF Author:
Publisher:
ISBN:
Category : Carcinogenesis
Languages : en
Pages : 154

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MECHANISM OF ENVIRONMENTAL CARCINOGENESIS

MECHANISM OF ENVIRONMENTAL CARCINOGENESIS PDF Author: J. Carl Barrett
Publisher: CRC-Press
ISBN: 9780849346729
Category : Medical
Languages : en
Pages : 144

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Mechanisms of Environmental Mutagenesis-Carcinogenesis

Mechanisms of Environmental Mutagenesis-Carcinogenesis PDF Author: A. Kappas
Publisher: Springer Science & Business Media
ISBN: 1461538084
Category : Medical
Languages : en
Pages : 276

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Book Description
The 19th annual meeting of the European Environmental Mutagen Society was held in Rhodes, Greece, from October 21st to 26th, 1989. The programme was chosen to explore what is currently known about the mechanisms of mutagenesis and carcinogenesis, induced by environmental agents, and the questions regarding the relationship of these two processes. Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy. Researchers from allover the world contributed to the programme of the meeting with posters and oral presentations, providing a variety of new data and interesting scientific approaches. A number of outstanding scientists were invited to present the results of their work. It is only their presenta tions which are included in this book, covering the following topics: Mutations and carcinogenesis; mechanisms of chemical ly-induced genetic effects on molecular, chromosomal and cell division level; adaptability and repair mechanisms; chemical carcinogenesis and oncogenes; structure and metabolism of mutagens-carcinogens; biomonitoring and epidemiology of humans exposed to environmental mutagens-carcinogens. For the sake of evaluating and controlling the mutagenic and carcinogenic potential of our environment it is indispens able to understand the mechanisms and processes by which chemicals act on the genetic material, causing either heredi tary disease or cancer. The pUblication of these proceedings will hopefully contribute to this task.

Mechanisms of Carcinogenesis

Mechanisms of Carcinogenesis PDF Author: Elizabeth K. Weisburger
Publisher: Springer Science & Business Media
ISBN: 9400925263
Category : Medical
Languages : en
Pages : 210

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but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.

Control of Carcinogens in the Environment

Control of Carcinogens in the Environment PDF Author: United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Commerce, Transportation, and Tourism
Publisher:
ISBN:
Category : Carcinogenesis
Languages : en
Pages : 570

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MECHANISM OF ENVIRONMENTAL CARCINOGENIS

MECHANISM OF ENVIRONMENTAL CARCINOGENIS PDF Author: J. Carl Barrett
Publisher: CRC-Press
ISBN: 9780849346712
Category : Medical
Languages : en
Pages : 0

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Mechanisms of Environmental Carcinogenesis: Role of genetic and epigenetic changes

Mechanisms of Environmental Carcinogenesis: Role of genetic and epigenetic changes PDF Author:
Publisher:
ISBN:
Category : Carcinogenesis
Languages : en
Pages : 168

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Environmental Carcinogenesis

Environmental Carcinogenesis PDF Author: Piet Emmelot
Publisher: North Holland
ISBN:
Category : Medical
Languages : en
Pages : 424

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How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease PDF Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728

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Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Environmental Carcinogenesis

Environmental Carcinogenesis PDF Author:
Publisher: Elsevier
ISBN: 0323997767
Category : Medical
Languages : en
Pages : 382

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Book Description
Environmental Carcinogenesis, Volume 96 in the Advances in Pharmacology series, reports on work done with carcinogenic metals and the mechanisms of their carcinogenicity, including Arsenic and Chromate. Chapters in this release include Breast cancer carcinogenesis by organophosphate pesticides, Polyadenylation of Canonical histone H3.1 in Carcinogenesis, Epigenomic reprogramming in iAs-mediated carcinogenesis, MicroRNAs and epigenetic regulation in metal-induced angiogenesis and carcinogenesis, Environmental epigenetics and new mechanistic markers of chemical exposure, Arsenic carcinogenesis by inhibition of DNA repair, Genetic and environmental reprogramming of the sarcoma epigenome, Mechanism of chromate carcinogenesis by chromatin alterations, and more. Other chapters cover Arsenic carcinogenesis and microRNAs, Epigenetic mechanism of Cr(VI)-induced cell malignant transformation and tumorigenesis, The dark side of NRF2 in arsenic carcinogenesis, and Chemical mechanisms of DNA damage by carcinogenic chromium(VI). Covers metal carcinogens Includes discussions on the mechanisms of cancer formation Provides updates on the diverse mechanisms that drive cancer formation by metals