Mechanical Properties of Collagen Fibrils and Elastic Fibers Explored by AFM PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Mechanical Properties of Collagen Fibrils and Elastic Fibers Explored by AFM PDF full book. Access full book title Mechanical Properties of Collagen Fibrils and Elastic Fibers Explored by AFM by Lanti Yang. Download full books in PDF and EPUB format.
Author: Lanti Yang
Publisher:
ISBN: 9789036526234
Category :
Languages : en
Pages : 152
Get Book Here
Book Description
Author: Lanti Yang
Publisher:
ISBN: 9789036526234
Category :
Languages : en
Pages : 152
Get Book Here
Book Description
Author: Peter Fratzl
Publisher: Springer Science & Business Media
ISBN: 0387739068
Category : Technology & Engineering
Languages : en
Pages : 516
Get Book Here
Book Description
Not only does this book provide a comprehensive review of current research advances in collagen structure and mechanics, it also explores this biological macromolecule’s many applications in biomaterials and tissue engineering. Readers gain an understanding of the structure and mechanical behavior of type I collagen and collagen-based tissues in vertebrates across all length scales, from the molecular (nano) to the organ (macro) level.
Author: Roger Carl Haut
Publisher:
ISBN:
Category : Collagen
Languages : en
Pages : 164
Get Book Here
Book Description
Author: Zhilei Liu Shen
Publisher:
ISBN:
Category : Biomedical materials
Languages : en
Pages : 255
Get Book Here
Book Description
Collagenous tissues (e.g. bone and tendon) have well organized hierarchical structures. To improve understanding of the mechanical behavior of collagenous tissues and to guide the development of multiscale models, mechanical testing at different length scales is required. Whole tissues, fascicles, and fibril bundles have been studied extensively, but little is known at the fibrillar level. Using microelectromechanical systems (MEMS) technology, tensile mechanical testing was performed on type I collagen fibril specimens isolated from the dermis of sea cucumbers. In air uniaxial tensile tests showed that the fibrils had a small strain elastic modulus of 860 ± 450 MPa, a yield stress of 220 ± 140 MPa, and a yield strain of 21% ± 13%. In vitro fracture tests showed that the fibrils had an elastic modulus of 470 ± 410 MPa, a fracture strength of 230 ± 160 MPa, and a fracture strain of 80% ± 44%. The fibrils displayed significantly lower elastic modulus in vitro than in air. Both the fracture strength/strain obtained in vitro and in air were significantly larger than those obtained in vacuo, indicating that the difference arises from the lack of intrafibrillar water molecules produced by vacuum drying. Fracture strength/strain of fibril specimens were different from those reported for collagenous structures of higher hierarchical levels, indicating the importance of obtaining these properties at the fibrillar level for multiscale modeling. In vitro coupled creep and stress relaxation tests demonstrated the intrinsic viscoelastic behavior of collagen fibrils. The stress-strain-time data were fitted using a Kelvin model consisting of a spring and a dashpot in parallel. The fibrils showed an elastic modulus of 180 ± 100 MPa, a viscosity of 4.7 ± 3.2 GPa*sec, and a relaxation time of 29 ± 16 sec. The fibrillar relaxation time was smaller than the tissue-level relaxation time, suggesting tissue relaxation is dominated by non-collagenous components (e.g. proteoglycans). To our knowledge, in vitro fracture and viscoelastic properties of isolated collagen fibrils were measured for the first time. The mechanical properties obtained in this work can be used as input parameters for multiscale modeling and help guide the development of synthetic biomaterials.
Author: Ghassan S. Kassab
Publisher: Springer
ISBN: 303014819X
Category : Science
Languages : en
Pages : 579
Get Book Here
Book Description
This comprehensive text examines both global and local coronary blood flow based on morphometry and mechanical properties of the coronary vasculature. Using a biomechanical approach, this book addresses coronary circulation in a quantitative manner based on models rooted in experimental data that account for the various physical determinants of coronary blood flow including myocardial-vessel interactions and various mechanisms of autoregulation. This is the first text dedicated to a distributive analysis (as opposed to lumped) and provides digital files for detailed anatomical data (e.g., diameters, lengths, node-to-node connections) of the coronary vessels. This book also provides appendices with specific mathematical formulations for the biomechanical analyses and models in the text. Written by Dr. Ghassan S. Kassab, a leader in the field of coronary biomechanics, Coronary Circulation: Anatomy, Mechanical Properties, and Biomechanics is a synthesis of seminal topics in the field and is intended for clinicians, bioengineers, and researchers as a compendium on the topic. The detailed anatomical and mechanical data provided are intended to be used as a platform to address new questions in this exciting and clinically very important research area.
Author: James Michael Brennan
Publisher:
ISBN:
Category : Collagen
Languages : en
Pages : 196
Get Book Here
Book Description
Author: F. R. Morgan
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Author: Peter D. Yurchenco
Publisher: Academic Press
ISBN: 1483289427
Category : Science
Languages : en
Pages : 483
Get Book Here
Book Description
The complex and critical process of extracellular matrix (ECM) assembly is described in this book. Assembly may involve molecules interacting with molecules of the same matrix class, such as in collagen, or interactions between different ECM molecules, such as in basement membranes. The text shows how this is driven by structural information within the matrix monomer. This information will be of interest to cell, developmental, and molecular biologists, biochemists, biophysicists, and biomedical researchers involved in macromolecular assembly, biological macromolecules, and extracellular matrix. Addresses assembly of most of the known classes of extracellular matrix macromolecules Discusses higher order structures produced by ECM Gives important concepts in ECM and cell-matrix interactions, Protein structure and protein-protein interactions, Development and tissue remodeling
Author: Farshid Guilak
Publisher: Boom Koninklijke Uitgevers
ISBN: 9780387220130
Category : Medical
Languages : en
Pages : 452
Get Book Here
Book Description
-Softcover reprint of a successful hardcover reference (370 copies sold) -Price to be accessible to the rapidly increasing population of students and investigators in the field of tissue engineering -Chapters written by well-known researchers discuss issues in functional tissue engineering as well as provide guidelines and a summary of the current state of technology
Author: F. R. Morgan
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
