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Author: Victor Lodato
Publisher: Anchor Canada
ISBN: 038566981X
Category : Fiction
Languages : en
Pages : 322
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Book Description
A fiercely funny and touching debut novel of a young girl uncovering the truth about her sister’s death. Fear doesn’t come naturally to Mathilda Savitch. She prefers to look directly at things nobody else can even mention: for example, her beloved older sister’s death. She was pushed in front of a train by a man who is still on the loose, and after a year of searching for clues, Mathilda has come no closer to the truth about Helene’s murder…until she cracks her email password and a whole secret life emerges — one that swiftly draws Mathilda into her sister’s world of clouded motives and strange emotions. If she can find the keys to Helene’s past, she’s sure she can wake her family from their nightmare of grief. But in crossing into that underworld and tracing her sister’s footsteps, she has to risk everything that matters to her. Mathilda Savitch is a poignant, furiously funny, and tender page-turner from an extraordinary debut novelist.
Author: Victor Lodato
Publisher: Anchor Canada
ISBN: 038566981X
Category : Fiction
Languages : en
Pages : 322
Get Book
Book Description
A fiercely funny and touching debut novel of a young girl uncovering the truth about her sister’s death. Fear doesn’t come naturally to Mathilda Savitch. She prefers to look directly at things nobody else can even mention: for example, her beloved older sister’s death. She was pushed in front of a train by a man who is still on the loose, and after a year of searching for clues, Mathilda has come no closer to the truth about Helene’s murder…until she cracks her email password and a whole secret life emerges — one that swiftly draws Mathilda into her sister’s world of clouded motives and strange emotions. If she can find the keys to Helene’s past, she’s sure she can wake her family from their nightmare of grief. But in crossing into that underworld and tracing her sister’s footsteps, she has to risk everything that matters to her. Mathilda Savitch is a poignant, furiously funny, and tender page-turner from an extraordinary debut novelist.
Author: Frances M. Ashcroft
Publisher: Academic Press
ISBN: 0080535216
Category : Science
Languages : en
Pages : 505
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Book Description
Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as the channelopathies. Ion Channels and Disease provides an informative and up-to-date account of our present understanding of ion channels and the molecular basis of ion channel diseases. It includes a basic introduction to the relevant aspects of molecular biology and biophysics and a brief description of the principal methods used to study channelopathies. For each channel, the relationship between its molecular structure and its functional properties is discussed and ways in which genetic mutations produce the disease phenotype are considered. This book is intended for research workers and clinicians, as well as graduates and advanced undergraduates. The text is clear and lively and assumes little knowledge, yet it takes the reader to frontiers of what is currently known about this most exciting and medically important area of physiology. Introduces the relevant aspects of molecular biology and biophysics Describes the principal methods used to study channelopathies Considers single classes of ion channels with summaries of the physiological role, subunit composition, molecular structure and chromosomal location, plus the relationship between channel structure and function Looks at those diseases associated with defective channel structures and regulation, including mutations affecting channel function and to what extent this change in channel function can account for the clinical phenotype
Author: Victor Lodato
Publisher: Macmillan
ISBN: 1250096987
Category : Fiction
Languages : en
Pages : 544
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Book Description
Eight-year-old Edgar Fini's loyalty is torn between the two women in his life. There's his mother, Lucy, who, though she has moments where she loves him, mostly disappears at night with her various 'suitors'. And then there's his grandmother, Florence, who dotes on him to the point where she is at a loss when he isn't around. Since his father's suicide, Florence and Edgar's relationship has become obsessive, each fully dependent on the other. When Florence suddenly dies, Lucy is thrown into the role of main caretaker and doesn't know how to handle her new job. But as Edgar and Lucy adjust, they must also deal with Ron, a local butcher who wants to court Lucy, and Conrad, an unsettlingly attentive adult whose intentions are at one more sinister and more innocent than Edgar could ever know.
Author: Kirsten Reed
Publisher: Text Publishing
ISBN: 1921520744
Category : Fiction
Languages : en
Pages : 218
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Book Description
We stopped at a roadside diner. People asked if I was his daughter. They ask all the time. Hoping, accusing. We never say yes, and we never say no. We ate our food at a booth in a hungry, self-conscious rush, straight out of the wrappers. They didn't have plates. We left a tip, just change. The waitress scooped it up straight away as we slid out of the booth. She was middle-aged and bulgy, in a proper matronly waitress's dress. She shot us what I suppose was intended to be a look of gratitude. She really only managed a weak glare. I guess that's the countryside for you. People are a little edgy.' Across the heartless expanse of middle America, a teenaged girl is riding shotgun with an older man. She watches him; she sees her fascination tallied in the black looks of waitresses, the knowing smiles of motel clerks. The man can see no proper way of conducting this relationship but is bound to her by concern and tenderness; perhaps desire. The girl craves only closeness. She knows the Ice Age is coming, and we will need to huddle together for warmth. Kirsten Reed's debut novel, with its echoes of Nabokov, Kerouac and Bret Easton Ellis, captures the translucent moment at the end of childhood in all its awkwardness, sincerity and heedless vulnerability. In prose both lyrical and earthy, comic and darkly harrowing, this extraordinary young writer creates a journey of irresistible momentum and tragic possibility. It will leave you with the sense that you have met someone significant; and you will not soon forget her.
Author: Wally Lamb
Publisher: Simon and Schuster
ISBN: 1471105342
Category : Fiction
Languages : en
Pages : 480
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Book Description
Meet Dolores Price. She's thirteen, wise-mouthed but wounded. Beached like a whale in front of her bedroom TV, she spends the next few years nourishing herself with the chocolate, crisps and Pepsi her anxious mother supplies. When she finally rolls into young womanhood at 257 pounds, Dolores is no stronger and life is no kinder. But this time she's determined to rise to the occasion and give herself one more chance before really going belly up. In his extraordinary coming-of-age odyssey, Wally Lamb invites us to hitch an incredible ride on a journey of love, pain, and renewal with the most heartbreakingly comical heroine to come along in years. At once a fragile girl and a hard-edged cynic, so tough to love yet so inimitably loveable, Dolores is as poignantly real as our own imperfections.
Author: Tupelo Hassman
Publisher: Farrar, Straus and Giroux
ISBN: 146680145X
Category : Fiction
Languages : en
Pages : 282
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Book Description
Rory Hendrix is the least likely of Girl Scouts. She hasn't got a troop or even a badge to call her own. But she's checked the Handbook out from the elementary school library so many times that her name fills all the lines on the card, and she pores over its surreal advice (Uniforms, disposing of outgrown; The Right Use of Your Body; Finding Your Way When Lost) for tips to get off the Calle: that is, the Calle de las Flores, the Reno trailer park where she lives with her mother, Jo, the sweet-faced, hard-luck bartender at the Truck Stop. Rory's been told that she is one of the "third-generation bastards surely on the road to whoredom." But she's determined to prove the county and her own family wrong. Brash, sassy, vulnerable, wise, and terrified, she struggles with her mother's habit of trusting the wrong men, and the mixed blessing of being too smart for her own good. From diary entries, social workers' reports, half-recalled memories, arrest records, family lore, Supreme Court opinions, and her grandmother's letters, Rory crafts a devastating collage that shows us her world even as she searches for the way out of it. Tupelo Hassman's Girlchild is a heart-stopping and original debut.
Author: A. C. Weisbecker
Publisher: Penguin
ISBN: 1101127554
Category : Fiction
Languages : en
Pages : 225
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Book Description
Soon to be a major motion picture starring John Cusack! Mr. Quark is a down-on-his luck pot-smuggler hiding out in the mountains of Colombia with his dog, High Pockets, and a small band of banditos led by the irascible Jose. Only months before, these three and their fearless associates were rolling in millions in cash and high-grade marijuana, eluding prosecution on “ridiculously false” drug and terrorism charges. But times have quickly grown lean, and to liven up their exile, Jose decides to mug a family of American tourists. Among the spoils are physics texts, which launch Mr. Quark on a side-splitting, boisterous adventure north to California, where he confronts the owner of the books with his own theories on relativity, the nature of the universe, and looking for the meaning of life in all the wrong places….
Author: Sandra Cisneros
Publisher: Vintage
ISBN: 0307960862
Category : Fiction
Languages : en
Pages : 112
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Book Description
Have You Seen Marie? showcases the storytelling magic of Sandra Cisneros, beloved author of The House on Mango Street and winner of the 2019 PEN/Nabokov Award for Achievement in International Literature. This lyrically told, richly illustrated fable for adults is the tale of a woman's search, in the wake of her mother's death, for a missing cat-and a reminder that love, even when it goes astray, does not stay lost forever.
Author: Jo Ann Beard
Publisher: Little, Brown
ISBN: 0316175161
Category : Fiction
Languages : en
Pages : 304
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Book Description
From the acclaimed author of The Boys of My Youth and Festival Days, a “mesmerizing… beautifully written” debut novel that evokes the wrenching, exquisite moment just before we step into adulthood (Ann Patchett). The fourteen-year-old narrator of In Zanesville is a late bloomer. She flies under the radar — a sidekick, a marching-band dropout, a disastrous babysitter. Luckily, she has a best friend with whom she shares the everyday adventures of a 1970s American girlhood, incidents through which a world is revealed and character is forged. In time, the two girls' friendship is tested — by their families' claims on them, by a clique of popular girls who stumble upon them, and by their first startling, subversive intimations of womanhood. With dry wit and piercing observation, Jo Ann Beard shows us that in the seemingly quiet streets of America's innumerable Zanesvilles is a universe of wonders, and that within the souls of the awkward and the overlooked often burns something radiant. "Probably my favorite novel of the year...A marvelous reading experience...I don't think I'll ever forget the unnamed, perfectly realized narrator of In Zanesville." —Nancy Pearl, NPR
Author: Mark Slouka
Publisher: W. W. Norton & Company
ISBN: 0393239756
Category : Fiction
Languages : en
Pages : 288
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Book Description
Still reeling from the death of his older brother, a sixteen-year-old track star befriends a street-fighting rebel and together they search for redemption amidst the social changes of 1968.
