Mass Spectrometric Investigation and Determination of Proteome Composition of Human Skin Tissues Ablated Using Picosecond Infrared Laser (PIRL) in a "layer by Layer" Approach PDF Download
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Author: Parnian Kiani
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Author: Parnian Kiani
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
Author: Parnian Kiani
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Marek Domin
Publisher: Royal Society of Chemistry
ISBN: 1849739269
Category : Science
Languages : en
Pages : 528
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Book Description
Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation. Introducing the subject and explaining the basic concepts and terminology, this book will provide a comprehensive, unique treatise devoted to the subject. Written by acknowledged experts, there are full descriptions on how new ionization techniques work, with an overview of their strengths, weaknesses and applications. This title will bring the reader right up to date, with both applications and theory, and will be suitable as a tutorial text for those starting in the field from a variety of disciplines.
Author: T. Agner
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318055867
Category : Medical
Languages : en
Pages : 172
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Book Description
Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration are discussed as well. Further sections are dedicated to clinical implications of skin barrier integrity, factors influencing the penetration of the skin, influence of wet work, and guidance for prevention and saving the barrier. Distinguished researchers have contributed to this book, providing a comprehensive and thorough overview of the skin barrier function. Researchers in the field, dermatologists, occupational physicians, and related industry will find this publication an essential source of information.
Author: Mary S. Lipton
Publisher: Humana Press
ISBN: 9781627037969
Category : Science
Languages : en
Pages : 0
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Book Description
When the last edition of this book was published in 2000, the field of proteomics was in its infancy. At that time, multidimensional liquid chromatographic separations were being introduced as an alternative to traditional gel-based techniques for separating complex protein and peptide mixtures prior to mass spectrometric detection. Today, this approach – referred to as shotgun proteomics – is considered routine for lar- scale global analyses of protein mixtures. Now in its adolescence, proteomics is fundamentally transforming biological and medical research. Much of this transformation can be attributed to technological advancements, particularly in mass spectrometry. Much wider accessibility of hi- resolution and mass measurement accuracy instrumentation in recent years has ini- ated a new revolution in the field by providing more reliable data and shifting the focus from cataloging proteins to precisely quantifying changes in protein abundance over time and in response to stimuli. Advanced mass spectrometers and novel ion d- sociation schemes such as electron transfer/capture dissociation make it possible to venture boldly into the maze of protein posttranslational modifications, which are an integral component of understanding functional proteomics in the spatial and t- poral domains. Another area that has benefited from these advancements is top-down proteomics, an emerging method essential for characterizing various protein variants that has potentially high impact in biomedical research.
Author: Kei Zaitsu
Publisher: Elsevier
ISBN: 0128172215
Category : Science
Languages : en
Pages : 294
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Book Description
Ambient Ionization Mass Spectrometry in Life Sciences: Principles and Applications is a systematic introduction to this rapidly expanding area of study. Underlying principles of each technique are explained in detail, along with discussions on their applications across life science disciplines. Ambient ionization has recently emerged as one of the hottest and fastest growing topics in mass spectrometry, hence this book is not just for analysts and researchers who use and study mass spectrometry. This volume would be of interest to anyone who works in or studies analytical chemistry, omics sciences (including metabolomics), pharmacokinetics, forensic science or drug analysis. - Covers the most up-to-date techniques, including DART, DCBI, DESI, PESI, PSI, REIMS and laser-based ambient ionization - Includes easy-to-understand pros and cons of each ionization technique to aid in decision-making - Provides plentiful examples of life science applications
Author: Christian Ngô
Publisher: Springer Science & Business Media
ISBN: 9462390126
Category : Technology & Engineering
Languages : en
Pages : 526
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Book Description
A new high-level book for professionals from Atlantis Press providing an overview of nanotechnologies now and their applications in a broad variety of fields, including information and communication technologies, environmental sciences and engineering, societal life, and medicine, with provision of customized treatments. The book shows where nanotechnology is now - a fascinating time when the science is transitioning into complex systems with impact on new products. Present and future developments are addressed, as well as a larger number of new industrial and research opportunities deriving from this domain. An overview for professionals, researchers and policy-makers of this very rapidly expanding field. Brief chapters and colour figures with a contained overall length make the book attractive at an attractive price - a must for every professional’s shelf. Mihail C. Roco, National Science Foundation and National Nanotechnology Initiative, wrote the preface underlying the importance and weight of the present book to this exciting and epoch-awakening field of research and applications: “Nanotechnology is well recognized as a science and technology megatrend for the beginning of the 21st century. This book aims to show where nanotechnology is now - transitioning to complex systems and fundamentally new products - and communicates the societal promise of nanotechnology to specialists and the public. Most of what has already made it into the marketplace is in the form of “First Generation” products, passive nanostructures with steady behaviour. Many companies have “Second Generation” products, active nanostructures with changing behaviour during use, and embryonic “Third Generation” products, including 3-dimensional nanosystems. Concepts for “Fourth Generation” products, including heterogeneous molecular nanosystems, are only in research.”
Author: James P. Stannard
Publisher: Thieme
ISBN: 160406630X
Category : Medical
Languages : en
Pages : 979
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Book Description
Winner of First Prize in Orthopaedics and Rheumatology at the 2008 British Medical Association Medical Book Competition Winner of Association of American Publishers Best Book in Clinical Medicine, 2007This landmark multimedia reference presents the most current information on surgical treatments of a wide range of injuries, from complex pelvic and spinal trauma to periarticular fractures and knee dislocations. For each injury, the authors guide the reader from the clinical evaluation, through the decision-making process, and to the surgical procedure. Each chapter provides a thorough review of surgical anatomy, streamlined discussion of the classification of the injury, the non-operative treatments available, and the indications for surgical treatment. Concise, step-by-step descriptions of surgical techniques are supplemented by carefully edited videos of surgical procedures on four accompanying DVDs, containing over 18 hours of video footage. Highlights of the book: Tips and Tricks summarize key points of each procedure for rapid review in preparation for surgery Exam Pearls describe injuries, incidence, indications for surgery, and possible complications and are ideal for board preparation More than 1,400 photographs, radiographs, and drawings illustrate techniques New Techniques sections cover the latest innovations for surgical management A separate table of contents for the four DVDs and shaded text boxes throughout the book enable convenient book-to-video reference Highlights of the DVDs: Narrated videos of entire surgical procedures provide a window into the operating room--an invaluable resource for residents and general orthopedic surgeons who do not perform trauma procedures regularly Coverage of state-of-the-art techniques such as locked plating, minimally invasive fracture fixation, advanced intramedullary nailing strategies, staged reconstruction of periarticular fractures, new techniques for hip hemiarthroplasty, surgical management of knee dislocation, including double bundle ACL and PCL knee reconstruction, and the use of temporary postoperative hinged external fixation Each DVD has been professionally produced and features high-quality audio, special effects, and multiple camera angles for each procedure Authoritative and comprehensive in its scope, this landmark text will be an invaluable asset in libraries of all orthopedic surgeons, residents, or specialists seeking a comprehensive and didactic reference.
Author: Kenzo Hiraoka
Publisher: Springer Science & Business Media
ISBN: 1461472334
Category : Science
Languages : en
Pages : 241
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Book Description
Most research and all publications in mass spectrometry address either applications or practical questions of procedure. This book, in contrast, discusses the fundamentals of mass spectrometry. Since these basics (physics, chemistry, kinetics, and thermodynamics) were worked out in the 20th century, they are rarely addressed nowadays and young scientists have no opportunity to learn them. This book reviews a number of useful methods in mass spectrometry and explains not only the details of the methods but the theoretical underpinning.
Author: Josefine Neuendorf
Publisher: Springer Nature
ISBN: 3030159116
Category : Medical
Languages : en
Pages : 252
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Book Description
This book is a comprehensive resource and up-to-date description of all urinary sediment constituents which are presented in bright-field mode and in phase-contrast mode. Thanks to numerous detailed images of urinary sediment constituents, the reader is able to easily compare what they view microscopically with high-resolution photographs and short films. The book is also designed to aid the identification of rare urine constituents in their native state without prior staining. It also features guidance on how set-up a microscope , microscopy techniques, and preanalytics. Exercises focused on microscopic analysis and diagnosis and a urinary sediment quiz reinforce key concepts to aid learning. Urine Sediment provides a practically applicable guide to the recognition of urinary sediment constituents. It is therefore a critical resource for trainees and experienced practitioners in urology, nephrology, gynecology and general practice who need to be able to accurately and quickly identify urine sediment constituents.
