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Author: Daniel Kling
Publisher: Elsevier
ISBN: 012818423X
Category : Law
Languages : en
Pages : 202
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Book Description
Mass Identifications: Statistical Methods in Forensic Genetics summarizes the state-of-the-art in the field, including methods and recent development in genetics (sequencing). The book's authors focus on practical applications and implementation, helping readers determine how to approach the problem to identify individuals using DNA and statistically summarize evidence. Written by leading experts in the field for forensic scientists, geneticists, forensic anthropologists, and pathologists working with identifications, the book is ideal for scientists and practitioners in many areas. Focuses on methods, challenges and solutions in DVI cases Covers the use of DNA databases searches and the statistical evaluation of genetic comparisons Includes exercises at the end of the book
Author: Daniel Kling
Publisher: Elsevier
ISBN: 012818423X
Category : Law
Languages : en
Pages : 202
Get Book Here
Book Description
Mass Identifications: Statistical Methods in Forensic Genetics summarizes the state-of-the-art in the field, including methods and recent development in genetics (sequencing). The book's authors focus on practical applications and implementation, helping readers determine how to approach the problem to identify individuals using DNA and statistically summarize evidence. Written by leading experts in the field for forensic scientists, geneticists, forensic anthropologists, and pathologists working with identifications, the book is ideal for scientists and practitioners in many areas. Focuses on methods, challenges and solutions in DVI cases Covers the use of DNA databases searches and the statistical evaluation of genetic comparisons Includes exercises at the end of the book
Author: Michael Kinter
Publisher: John Wiley & Sons
ISBN: 0471231886
Category : Science
Languages : en
Pages : 321
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Book Description
How to design, execute, and interpret experiments for protein sequencing using mass spectrometry The rapid expansion of searchable protein and DNA databases in recent years has triggered an explosive growth in the application of mass spectrometry to protein sequencing. This timely and authoritative book provides professionals and scientists in biotechnology research with complete coverage of procedures for analyzing protein sequences by mass spectrometry, including step-by-step guidelines for sample preparation, analysis, and data interpretation. Michael Kinter and Nicholas Sherman present their own high-quality, laboratory-tested protocols for the analysis of a wide variety of samples, demonstrating how to carry out specific experiments and obtain fast, reliable results with a 99% success rate. Readers will get sufficient experimental detail to apply in their own laboratories, learn about the proper selection and operation of instruments, and gain essential insight into the fundamental principles of mass spectrometry and protein sequencing. Coverage includes: * Peptide fragmentation and interpretation of product ion spectra * Basic polyacrylamide gel electrophoresis * Preparation of protein digests for sequencing experiments * Mass spectrometric analysis using capillary liquid chromatography * Techniques for protein identification by database searches * Characterization of modified peptides using tandem mass spectrometry And much more
Author: Amanda C Sozer
Publisher: CRC Press
ISBN: 1466513845
Category : Law
Languages : en
Pages : 318
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Book Description
Advances in DNA technology have expanded such that forensic DNA profiling is now considered a routine method for identifying victims of mass fatalities. Originating from an initiative funded by a grant from the U.S. Department of State, DNA Analysis for Missing Person Identification in Mass Fatalities presents a collection of training modules that supply comprehensive instruction in these complex techniques. The book begins with a concise overview of DNA analysis methods and their use in identifying victims of mass fatalities. It then goes on to explore: Mass fatality response operations, including body recovery, mortuary operations, family assistance, the identification of human remains, and psychosocial support for families Best practices in DNA sample collection and the different types of reference samples that can be used to identify a reported missing (RM) individual Autosomal short tandem repeat (STR) DNA profile analysis and interpretation, and procedures to ensure data accuracy Major steps involved in generating a DNA profile and the complex aspects of data analysis and interpretation The importance of data management using information technology tools, and tips for maintaining quality operations Accreditation and standards and the major elements of a DNA quality program Setting up a laboratory operation, including planning, staffing, identifying types of equipment and supplies, and the procedures for ensuring that laboratory equipment performs appropriately The book includes a discussion of the key steps in the preparation, delivery, and evaluation of training sessions for personnel responding to a mass fatality human identification event. It also provides a comprehensive vocabulary list with terms related to mass fatality DNA identification. This text is a must-read for organizations contemplating the use of DNA in human identification initiatives following mass fatalities. It is also a tremendous value to emergency manager/planners, medical legal authorities, and forensic DNA laboratories.
Author: Robert P. Adams
Publisher: Academic Press
ISBN: 0323137946
Category : Science
Languages : en
Pages : 311
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Book Description
This handbook presents the ion trap mass spectra of the most common terpenes (hydrocarbons found in oils, resins, and balsams) found in nature, including relative retention/elution times, an extensive synonymy of common and IUPAC names, CAS registry numbers, molecular formulas, and structures. - Includes 502 spectra of essential oils from predominantly plant sources - Presents an overview of the ion trap system
Author: Ruth Parkin-Gounelas
Publisher: Routledge
ISBN: 0415510260
Category : Computers
Languages : en
Pages : 232
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Book Description
Within the context of shifting social bonds in global culture, this book brings together debates on the left from political philosophy, psychoanalysis, social psychology and media and cultural studies to explore the logic of the formation of collective identities from a new theoretical perspective.
Author: Mark S. Brodin
Publisher: Wolters Kluwer
ISBN: 0735560625
Category : Law
Languages : en
Pages : 890
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Book Description
Handbook of Massachusetts Evidence is the premier work in its field. This comprehensive and practical guide to the law of Massachusetts evidence gives you the latest case law and up-to-date information on all evidentiary matters, including:RelevanceNew kinds of scientific and statistical evidenceCharacter evidenceAdmissibility of confessionsPrivileges and disqualifications Domestic Abuse Prevention StatuteExpert testimony In addition, this new updated Eighth Edition has been expanded to cover recent topics such as: Expert testimony and scientific proof Hearsay Developments in criminal trials With detailed reference to all significant Massachusetts and federal cases with a bearing on the law of evidence, this trial attorney's 'bible' provides all the insightful analysis you need for practical, day-to-day use.
Author: National Institute of Justice (U.S.). Technical Working Group for Mass Fatality Forensic Identification
Publisher:
ISBN:
Category : Accident victims
Languages : en
Pages : 100
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Book Description
In a mass fatality incident, correct victim identification is essential to satisfying humanitarian considerations, meet civil and criminal investigative needs, and identify victim perpetrators. This report provides medical examiners/coroners with guidelines for preparing the portion of the disaster plan concerned with victim identification and summarizes the victim identification process for other first responders. It discusses the integration of the medical examiner/coroner into the initial response process, and presents the roles of various forensic disciplines (including forensic anthropology, radiology, odontology, fingerprinting, and DNA analysis) in victim identification. This guide represents the experience of dozens of Federal, State and private forensic experts who took part in the Technical Working Group for Mass Fatality Forensic Identification.
Author: Burkhard Madea
Publisher: John Wiley & Sons
ISBN: 1118570626
Category : Medical
Languages : en
Pages : 1312
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Book Description
Forensic Medicine encompasses all areas in which medicine and law interact. This book covers diverse aspects of forensic medicine including forensic pathology, traumatology and violent death, sudden and unexpected death, clinical forensic medicine, toxicology, traffic medicine, identification, haemogenetics and medical law. A knowledge of all these subdisciplines is necessary in order to solve routine as well as more unusual cases. Taking a comprehensive approach the book m.oves beyond a focus on forensic pathology to include clinical forensic medicine and forensic toxicology. All aspects of forensic medicine are covered to meet the specialist needs of daily casework. Aspects of routine analysis and quality control are addressed in each chapter. The book provides coverage of the latest developments in forensic molecular biology, forensic toxicology, molecular pathology and immunohistochemistry. A must-have reference for every specialist in the field this book is set to become the bench-mark for the international forensic medical community.
Author: Dennis Jenke
Publisher: John Wiley & Sons
ISBN: 1119605075
Category : Medical
Languages : en
Pages : 468
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Book Description
EXTRACTABLES AND LEACHABLES Learn to address the safety aspects of packaged drug products and medical devices Pharmaceutical drug products and medical devices are expected to be effective and safe to use. This includes minimizing patient, user or product exposure to impurities leached from these items when the drug product is administered or when the medical device is used. Clearly, patient or user exposure to leachables must not adversely impact their health and safety. Furthermore, these impurities must not adversely affect key quality attributes of the drug product or medical device, including its manufacturability, stability, efficacy, appearance, shelf-life and conformance to standards. Extractables and leachables are derived from the drug product’s packaging, manufacturing systems and/or delivery systems or from the medical device’s materials of construction. It is imperative to understand and quantify the release of extractables from these items, the accumulation of leachables in drug products and the release of leachables from medical devices. Once extractables and leachables have been discovered, identified and quantified, their effect on the key product or device quality attributes, including safety, must be systematically and scientifically established according to recognized, rigorous and relevant regulatory and compendial standards and industry-driven best practices. In Extractables and Leachables, the chemical compatibility (including safe use) of drugs (and their containers, delivery devices and manufacturing systems) and medical devices is examined at length, focusing particularly on how trace-level extractables and leachables affect the quality and safety of a medical product and how to assess the magnitude of the effect. This is accomplished by addressing the two critical activities required to develop, register and commercialize safe, effective and affordable clinical therapies; measuring extractables and leachables (chemical characterization) and assessing their impact (for example, toxicological safety risk assessment). Each of these activities is addressed in-depth, based on the existing and developing international regulations and guidelines, current published literature and the author’s extensive personal experience. Written by a key contributor to standards, guidelines, recommended practices and the scientific literature, the book provides “insider” insights beyond those gained by merely reading the relevant texts. Given that the rapidly evolving extractables and leachables landscape, this book provides the most current and crucial information on new and forthcoming regulations and best practices. Extractables and Leachables readers will also find: A thorough summary of regulatory and compendial guidelines and the steps required to meet them A detailed and in-depth review of essential scientific principles and recommended best practices for the design, implementation, interpretation and reporting of chemical characterization studies A practical resource for optimizing the development, registration, and commercialization of safe and effective medical products A helpful tool to maximize product development and successful regulatory outcomes Extractables and Leachables is the essential reference for pharmaceutical scientists, analytical chemists, regulatory affairs professionals, engineers, and toxicologists in areas such as product research and development, product registration and approval, regulatory affairs, analytical science, quality control, and manufacturing.
Author: Bradley J. Adams
Publisher: Springer Science & Business Media
ISBN: 1597453161
Category : Medical
Languages : en
Pages : 377
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Book Description
Commingling of human remains presents an added challenge to all phases of the forensic process. This book brings together tools from diverse sources within forensic science to offer a set of comprehensive approaches to handling commingled remains. It details the recovery of commingled remains in the field, the use of triage in the assessment of commingling, various analytical techniques for sorting and determining the number of individuals, the role of DNA in the overall process, ethical considerations, and data management. In addition, the book includes case examples that illustrate techniques found to be successful and those that proved problematic.
