Management of Chemical and Biological Samples for Screening Applications PDF Download
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Author: Mark Wigglesworth
Publisher: John Wiley & Sons
ISBN: 352732822X
Category : Medical
Languages : en
Pages : 435
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Book Description
Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.
Author: Mark Wigglesworth
Publisher: John Wiley & Sons
ISBN: 3527645268
Category : Medical
Languages : en
Pages : 435
Get Book Here
Book Description
Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.
Author: Mark Wigglesworth
Publisher: John Wiley & Sons
ISBN: 352732822X
Category : Medical
Languages : en
Pages : 435
Get Book Here
Book Description
Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.
Author: Jennie R. Lill
Publisher: John Wiley & Sons
ISBN: 1119384400
Category : Science
Languages : en
Pages : 426
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Book Description
The definitive guide to the myriad analytical techniques available to scientists involved in biotherapeutics research Analytical Characterization of Biotherapeutics covers all current and emerging analytical tools and techniques used for the characterization of therapeutic proteins and antigen reagents. From basic recombinant antigen and antibody characterization, to complex analyses for increasingly complex molecular designs, the book explores the history of the analysis techniques and offers valuable insights into the most important emerging analytical solutions. In addition, it frames critical questions warranting attention in the design and delivery of a therapeutic protein, exposes analytical challenges that may occur when characterizing these molecules, and presents a number of tested solutions. The first single-volume guide of its kind, Analytical Characterization of Biotherapeutics brings together contributions from scientists at the leading edge of biotherapeutics research and manufacturing. Key topics covered in-depth include the structural characterization of recombinant proteins and antibodies, antibody de novo sequencing, characterization of antibody drug conjugates, characterization of bi-specific or other hybrid molecules, characterization of manufacturing host-cell contaminant proteins, analytical tools for biologics molecular assessment, and more. Each chapter is written by a recognized expert or experts in their field who discuss current and cutting edge approaches to fully characterizing biotherapeutic proteins and antigen reagents Covers the full range of characterization strategies for large molecule based therapeutics Provides an up-to-date account of the latest approaches used for large molecule characterization Chapters cover the background needed to understand the challenges at hand, solutions to characterize these large molecules, and a summary of emerging options for analytical characterization Analytical Characterization of Biotherapeutics is an up-to-date resource for analytical scientists, biologists, and mass spectrometrists involved in the analysis of biomolecules, as well as scientists employed in the pharmaceuticals and biotechnology industries. Graduate students in biology and analytical science, and their instructors will find it to be fascinating and instructive supplementary reading.
Author: Bruce Budowle
Publisher: Academic Press
ISBN: 0128153806
Category : Medical
Languages : en
Pages : 528
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Book Description
Microbial Forensics, Third Edition, serves as a complete reference on the discipline, describing the advances, challenges and opportunities that are integral in applying science to help solve future biocrimes. New chapters include: Microbial Source Tracking, Clinical Recognition, Bioinformatics, and Quality Assurance. This book is intended for a wide audience, but will be indispensable to forensic scientists and researchers interested in contributing to the growing field of microbial forensics. Biologists and microbiologists, the legal and judicial system, and the international community involved with Biological Weapons Treaties will also find this volume invaluable. - Presents new and expanded content that includes a statistical analysis of forensic data, legal admissibility and standards of evidence - Discusses actual cases of forensic bioterrorism - Includes contributions from editors and authors who are leading experts in the field, with primary experience in the application of this fast-growing discipline
Author: Péter Horvatovich
Publisher: Royal Society of Chemistry
ISBN: 1849734224
Category : Medical
Languages : en
Pages : 385
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Book Description
This book covers proteomics biomarker discovery and validation procedures from the clinical perspective.
Author: Werngard Czechtizky
Publisher: John Wiley & Sons
ISBN: 1118771605
Category : Science
Languages : en
Pages : 546
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Book Description
Stressing strategic and technological solutions to medicinal chemistry challenges, this book presents methods and practices for optimizing the chemical aspects of drug discovery. Chapters discuss benefits, challenges, case studies, and industry perspectives for improving drug discovery programs with respect to quality and costs. • Focuses on small molecules and their critical role in medicinal chemistry, reviewing chemical and economic advantages, challenges, and trends in the field from industry perspectives • Discusses novel approaches and key topics, like screening collection enhancement, risk sharing, HTS triage, new lead finding approaches, diversity-oriented synthesis, peptidomimetics, natural products, and high throughput medicinal chemistry approaches • Explains how to reduce design-make-test cycle times by integrating medicinal chemistry, physical chemistry, and ADME profiling techniques • Includes descriptive case studies, examples, and applications to illustrate new technologies and provide step-by-step explanations to enable them in a laboratory setting
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309173442
Category : Technology & Engineering
Languages : en
Pages : 302
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Book Description
The threat of domestic terrorism today looms larger than ever. Bombings at the World Trade Center and Oklahoma City's Federal Building, as well as nerve gas attacks in Japan, have made it tragically obvious that American civilians must be ready for terrorist attacks. What do we need to know to help emergency and medical personnel prepare for these attacks? Chemical and Biological Terrorism identifies the R&D efforts needed to implement recommendations in key areas: pre-incident intelligence, detection and identification of chemical and biological agents, protective clothing and equipment, early recognition that a population has been covertly exposed to a pathogen, mass casualty decontamination and triage, use of vaccines and pharmaceuticals, and the psychological effects of terror. Specific objectives for computer software development are also identified. The book addresses the differences between a biological and chemical attack, the distinct challenges to the military and civilian medical communities, and other broader issues. This book will be of critical interest to anyone involved in civilian preparedness for terrorist attack: planners, administrators, responders, medical professionals, public health and emergency personnel, and technology designers and engineers.
Author:
Publisher:
ISBN:
Category : Trademarks
Languages : en
Pages : 976
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Book Description
Author: Management Association, Information Resources
Publisher: IGI Global
ISBN: 1799812111
Category : Technology & Engineering
Languages : en
Pages : 1680
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Book Description
As the world’s population continues to grow and economic conditions continue to improve, more solid and liquid waste is being generated by society. Improper disposal methods can not only lead to harmful environmental impacts but can also negatively affect human health. To prevent further harm to the world’s ecosystems, there is a dire need for sustainable waste management practices that will safeguard the environment for future generations. Waste Management: Concepts, Methodologies, Tools, and Applications is a vital reference source that examines the management of different types of wastes and provides relevant theoretical frameworks about new waste management technologies for the control of air, water, and soil pollution. Highlighting a range of topics such as contaminant removal, landfill treatment, and recycling, this multi-volume book is ideally designed for environmental engineers, waste authorities, solid waste management companies, landfill operators, legislators, environmentalists, policymakers, government officials, academicians, researchers, and students.
Author: Howard H. Guyer
Publisher: John Wiley & Sons
ISBN: 9780471299844
Category : Technology & Engineering
Languages : en
Pages : 616
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Book Description
INDUSTRIAL PROCESSES and WASTE STREAM MANAGEMENT This book provides environmental technology students with a quick, enjoyable way to master the knowledge and skills needed to develop and implement successful, cost-effective industrial pollution control programs, especially when used in coordination with the Industrial Processes and Waste Stream Management video series produced by INTELECOM Intelligent Telecommunications. The first section of the book lays the conceptual foundations with a detailed overview of waste stream management tools and regulations and the four EPA-approved treatment methods: physical, chemical, thermal, and biological. The following 20 chapters are organized by industry, and provide a fascinating case-by-case exploration of industrial processes and how the waste streams they generate are managed in all major industries, including petroleum, chemicals, mining, metals, paint, textiles, agriculture, paper, printing, nuclear, medical, and more. Features that make Industrial Processes and Waste Stream Management an ideal introduction to the subject for environmental technology students, include: * Acclaimed, user-friendly, modular format found in all the books in the Preserving the Legacy series * Basic anatomy, physiology, and chemistry concepts that help clarify how toxins interact with living tissue * Proven, rapid-learning modular format--each chapter features learning objectives, topic summaries, chapter-end reviews, and practice questions * Helpful sidebars that highlight critical concepts * More than 175 high-quality line drawings, photographs, diagrams, charts, and tables * Numerous easy-to-perform, skill-building classroom activities * A glossary of more than 1,000 essential terms * Extensive bibliography of recommended readings in all key subject areas Industrial Processes and Waste Stream Management is also an excellent refresher/quick-reference guide for practicing environmental technicians.
