Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity PDF Author: Franck Mauvais-Jarvis
Publisher: Springer
ISBN: 3319701789
Category : Medical
Languages : en
Pages : 630

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Book Description
The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity PDF Author: Franck Mauvais-Jarvis
Publisher: Springer
ISBN: 3319701789
Category : Medical
Languages : en
Pages : 630

Get Book Here

Book Description
The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

Disability, Work, and Cash Benefits

Disability, Work, and Cash Benefits PDF Author: Jerry L. Mashaw
Publisher: W E Upjohn Inst for
ISBN: 9780880991674
Category : Business & Economics
Languages : en
Pages : 427

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Book Description
This book contains 13 papers from a workshop convened to explore the causes of work disability and the types of interventions that might enable individuals to remain at work, return to work, or enter the work force for the first time, despite having chronic health conditions or impairments. Following an overview of the papers by editors Jerry L. Mashaw and Virginia P. Reno, the following papers are included: "The Contemporary Labor Market and the Employment Prospects of Persons with Disabilities" (Edward Yelin, Miriam Cisternas); "Employment and Economic Well-Being Following the Onset of a Disability: The Role for Public Policy" (Richard V. Burkhauser, Mary C. Daly); "Employment and Benefits for People with Diverse Disabilities" (Walter Y. Oi); "European Experiences with Disability Policy" (Leo J. M. Aarts, Philip R. de Jong); "Patterns of Return to Work in a Cohort of Disabled-Worker Beneficiaries" (Martynas A. Ycas); "The Effectiveness of Financial Work Incentives in Social Security Disability Insurance and Supplemental Security Income: Lessons from Other Transfer Programs" (Hilary Williamson Hoynes, Robert Moffitt); "Lessons from the Vocational Rehabilitation/Social Security Administration Experience" (Edward Berkowitz, David Dean); "Disability and Work: Lessons from the Private Sector" (H. Allan Hunt et al.); "Quantitative Outcomes of the Transitional Employment Training Demonstration: Summary of Net Impacts" (Aaron J. Prero); "Policies for People with Disabilities in U.S. Employment and Training Programs" (Burt S. Barnow); "Improving the Return to Work of Social Security Disability Beneficiaries" (Monroe Berkowitz); "People with Disabilities: Access to Health Care and Related Benefits" (Robert B. Friedland, Alison Evans); and "Health Care, Personal Assistance and Assistive Technology: Are In-Kind Benefits Key to Independence or Dependence for People with Disabilities?" (Andrew I. Batavia). The papers contain extensive references lists. (KC)

Major Management Challenges and Program Risks

Major Management Challenges and Program Risks PDF Author: United States. General Accounting Office
Publisher: DIANE Publishing
ISBN:
Category : Civil defense
Languages : en
Pages : 62

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Book Description


Major management challenges and program risks : Department of Education

Major management challenges and program risks : Department of Education PDF Author: United States. General Accounting Office
Publisher: DIANE Publishing
ISBN: 1428948473
Category : Education and state
Languages : en
Pages : 84

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Book Description


The Jefferson Bible

The Jefferson Bible PDF Author: Thomas Jefferson
Publisher: Courier Corporation
ISBN: 0486112519
Category : Religion
Languages : en
Pages : 98

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Book Description
Jefferson regarded Jesus as a moral guide rather than a divinity. In his unique interpretation of the Bible, he highlights Christ's ethical teachings, discarding the scriptures' supernatural elements, to reflect the deist view of religion.

Major Management Challenges and Program Risks

Major Management Challenges and Program Risks PDF Author: United States. General Accounting Office
Publisher: DIANE Publishing
ISBN: 1428948570
Category : Human services
Languages : en
Pages : 52

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Book Description
This report addresses the major performance and accountability challenges facing the Department of Labor as it seeks to promote the welfare and economic security of the nations work force and ensure that workplaces are safe and healthy. It includes a summary of actions that Labor has under way to address these challenges and outlines further actions that GAO believes are needed. This analysis should help the new Congress and administration carry out their responsibilities and improve government for the benefit of the American people.

Major Management Challenges and Program Risks

Major Management Challenges and Program Risks PDF Author: United States. General Accounting Office
Publisher:
ISBN:
Category : Justice, Administration of
Languages : en
Pages : 0

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Book Description
This report addresses the major performance and management challenges confronting the Department of Defense (DOD). Taken together, these challenges, if not addressed, can adversely affect the Department's operational effectiveness. The report also addresses corrective actions that DOD has taken or initiated on these issues- including DOD'S blueprint for a strategy-based, balanced, and affordable defense program as outlined in the May 1997 Report of the Quadrennial Defense Review and the reforms described in its November 1997 Defense Reform Initiative Report-and further actions that are needed. For many years, we have reported significant management problems at DOD. These problems can be categorized into two areas: (1) systemic management challenges dealing with financial management, information management, weapon systems acquisition, and contract management; and (2) program management challenges dealing with infrastructure, inventory management, and personnel. These problems cut across DOD'S program areas.

Human Genetics and Genomics

Human Genetics and Genomics PDF Author: Bruce R. Korf
Publisher: John Wiley & Sons
ISBN: 1118537661
Category : Medical
Languages : en
Pages : 280

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Book Description
This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions. A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice. Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today’s genetics teaching, and includes updated discussion of genetic risk assessment, “single gene” disorders and therapeutics. Key learning features include: Clinical snapshots to help relate science to practice 'Hot topics' boxes that focus on the latest developments in testing, assessment and treatment 'Ethical issues' boxes to prompt further thought and discussion on the implications of genetic developments 'Sources of information' boxes to assist with the practicalities of clinical research and information provision Self-assessment review questions in each chapter Accompanied by the Wiley E-Text digital edition (included in the price of the book), Human Genetics and Genomics is also fully supported by a suite of online resources at www.korfgenetics.com, including: Factsheets on 100 genetic disorders, ideal for study and exam preparation Interactive Multiple Choice Questions (MCQs) with feedback on all answers Links to online resources for further study Figures from the book available as PowerPoint slides, ideal for teaching purposes The perfect companion to the genetics component of both problem-based learning and integrated medical courses, Human Genetics and Genomics presents the ideal balance between the bio-molecular basis of genetics and clinical cases, and provides an invaluable overview for anyone wishing to engage with this fast-moving discipline.

Research on Women's Health

Research on Women's Health PDF Author:
Publisher:
ISBN:
Category : Women
Languages : en
Pages : 84

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Book Description


Major Management Challenges and Program Risks

Major Management Challenges and Program Risks PDF Author: United States Government Accountability Office
Publisher: Createspace Independent Publishing Platform
ISBN: 9781978446113
Category :
Languages : en
Pages : 58

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Book Description
GAO-03-102, Major Management Challenges and Program Risks: Department of Homeland Security