Electromechanobiology of Cartilage and Osteoarthritis

Electromechanobiology of Cartilage and Osteoarthritis PDF Author: Brianne K. Connizzo
Publisher: Springer Nature
ISBN: 3031255887
Category : Medical
Languages : en
Pages : 182

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Book Description
This is an open access book. In honor of his 75th birthday, we reflect on the impact of the pioneering work of Alan Grodzinsky and his laboratory. This volume includes in-depth discussions of tissue electromechanics, mechanobiology and biomechanics, and matrix biology in addition to the latest advancements in understanding the pathogenesis, progression and treatment of osteoarthritis. Unique to this volume, we overview decades of groundbreaking research that set the stage for the latest efforts in the field, highlighting the legacy of one researcher and their trainees.

Electromechanobiology of Cartilage and Osteoarthritis

Electromechanobiology of Cartilage and Osteoarthritis PDF Author: Brianne K. Connizzo
Publisher: Springer Nature
ISBN: 3031255887
Category : Medical
Languages : en
Pages : 182

Get Book Here

Book Description
This is an open access book. In honor of his 75th birthday, we reflect on the impact of the pioneering work of Alan Grodzinsky and his laboratory. This volume includes in-depth discussions of tissue electromechanics, mechanobiology and biomechanics, and matrix biology in addition to the latest advancements in understanding the pathogenesis, progression and treatment of osteoarthritis. Unique to this volume, we overview decades of groundbreaking research that set the stage for the latest efforts in the field, highlighting the legacy of one researcher and their trainees.

Machine Learning: Concepts, Methodologies, Tools and Applications

Machine Learning: Concepts, Methodologies, Tools and Applications PDF Author: Management Association, Information Resources
Publisher: IGI Global
ISBN: 1609608194
Category : Computers
Languages : en
Pages : 2174

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Book Description
"This reference offers a wide-ranging selection of key research in a complex field of study,discussing topics ranging from using machine learning to improve the effectiveness of agents and multi-agent systems to developing machine learning software for high frequency trading in financial markets"--Provided by publishe

Computational Biology for Stem Cell Research

Computational Biology for Stem Cell Research PDF Author: Pawan Raghav
Publisher: Elsevier
ISBN: 0443132216
Category : Science
Languages : en
Pages : 568

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Book Description
Computational Biology for Stem Cell Research is an invaluable guide for researchers as they explore HSCs and MSCs in computational biology. With the growing advancement of technology in the field of biomedical sciences, computational approaches have reduced the financial and experimental burden of the experimental process. In the shortest span, it has established itself as an integral component of any biological research activity. HSC informatics (in silico) techniques such as machine learning, genome network analysis, data mining, complex genome structures, docking, system biology, mathematical modeling, programming (R, Python, Perl, etc.) help to analyze, visualize, network constructions, and protein-ligand or protein-protein interactions. This book is aimed at beginners with an exact correlation between the biomedical sciences and in silico computational methods for HSCs transplantation and translational research and provides insights into methods targeting HSCs properties like proliferation, self-renewal, differentiation, and apoptosis. - Modeling Stem Cell Behavior: Explore stem cell behavior through animal models, bridging laboratory studies to real-world clinical allogeneic HSC transplantation (HSCT) scenarios. - Bioinformatics-Driven Translational Research: Navigate a path from bench to bedside with cutting-edge bioinformatics approaches, translating computational insights into tangible advancements in stem cell research and medical applications. - Interdisciplinary Resource: Discover a single comprehensive resource catering to biomedical sciences, life sciences, and chemistry fields, offering essential insights into computational tools vital for modern research.

Engineering and Physical Approaches to Cancer

Engineering and Physical Approaches to Cancer PDF Author: Ian Y. Wong
Publisher: Springer Nature
ISBN: 3031228022
Category : Medical
Languages : en
Pages : 334

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Book Description
Engineering and Physical Approaches to Cancer addresses the newest research at this interface between cancer biology and the physical sciences. Several chapters address the mechanobiology of collective and individual cell migration, including experimental, theoretical, and computational perspectives. Other chapters consider the crosstalk of biological, chemical, and physical cues in the tumor microenvironment, including the role of senescence, polyploid giant cells, TGF-beta, metabolism, and immune cells. Further, chapters focus on circulating tumor cells and metastatic colonization, highlighting both bioengineered models as well as diagnostic technologies. Further, this book features the work of emerging and diverse investigators in this field, who have already made impressive cross-disciplinary scientific contributions. This book is designed for a general audience, particularly researchers conversant in cancer biology but less familiar with engineering (and vice-versa). Thus, we envision that this book will be suitable for faculty, postdoctoral fellows, and advanced graduate students across medicine, biological sciences, and engineering. We also anticipate this book will be of interest to medical professionals and trainees, as well as researchers in the pharmaceutical and biomedical device industry. Describes physical aspects of cancer, including collective cell migration, the aberrant tumor microenvironment, circulating tumor cells, and metastatic colonization. First volume available on the topic of physical aspects of cancer

Preclinical Models and Emerging Technologies to Study the Effects of the Tumor Microenvironment on Cancer Heterogeneity and Drug Resistance

Preclinical Models and Emerging Technologies to Study the Effects of the Tumor Microenvironment on Cancer Heterogeneity and Drug Resistance PDF Author: Giulia Adriani
Publisher: Frontiers Media SA
ISBN: 2832537030
Category : Medical
Languages : en
Pages : 171

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Book Description


Computation in Cells and Tissues

Computation in Cells and Tissues PDF Author: R. Paton
Publisher: Springer Science & Business Media
ISBN: 3662063697
Category : Computers
Languages : en
Pages : 349

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Book Description
The field of biologically inspired computation has coexisted with mainstream computing since the 1930s, and the pioneers in this area include Warren McCulloch, Walter Pitts, Robert Rosen, Otto Schmitt, Alan Turing, John von Neumann and Norbert Wiener. Ideas arising out of studies of biology have permeated algorithmics, automata theory, artificial intelligence, graphics, information systems and software design. Within this context, the biomolecular, cellular and tissue levels of biological organisation have had a considerable inspirational impact on the development of computational ideas. Such innovations include neural computing, systolic arrays, genetic and immune algorithms, cellular automata, artificial tissues, DNA computing and protein memories. With the rapid growth in biological knowledge there remains a vast source of ideas yet to be tapped. This includes developments associated with biomolecular, genomic, enzymic, metabolic, signalling and developmental systems and the various impacts on distributed, adaptive, hybrid and emergent computation. This multidisciplinary book brings together a collection of chapters by biologists, computer scientists, engineers and mathematicians who were drawn together to examine the ways in which the interdisciplinary displacement of concepts and ideas could develop new insights into emerging computing paradigms. Funded by the UK Engineering and Physical Sciences Research Council (EPSRC), the CytoCom Network formally met on five occasions to examine and discuss common issues in biology and computing that could be exploited to develop emerging models of computation.

Computational Science – ICCS 2022

Computational Science – ICCS 2022 PDF Author: Derek Groen
Publisher: Springer Nature
ISBN: 3031087542
Category : Computers
Languages : en
Pages : 744

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Book Description
The four-volume set LNCS 13350, 13351, 13352, and 13353 constitutes the proceedings of the 22ndt International Conference on Computational Science, ICCS 2022, held in London, UK, in June 2022.* The total of 175 full papers and 78 short papers presented in this book set were carefully reviewed and selected from 474 submissions. 169 full and 36 short papers were accepted to the main track; 120 full and 42 short papers were accepted to the workshops/ thematic tracks. *The conference was held in a hybrid format

Machine Learning and Mathematical Models for Single-Cell Data Analysis

Machine Learning and Mathematical Models for Single-Cell Data Analysis PDF Author: Le Ou-Yang
Publisher: Frontiers Media SA
ISBN: 2832501842
Category : Science
Languages : en
Pages : 118

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Book Description


Viscoelasticity: From Individual Cell Behavior to Collective Tissue Remodeling

Viscoelasticity: From Individual Cell Behavior to Collective Tissue Remodeling PDF Author: Ivana Dusan Pajic-Lijakovic
Publisher: Frontiers Media SA
ISBN: 2889716953
Category : Science
Languages : en
Pages : 161

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Book Description


Biostatistical Genetics and Genetic Epidemiology

Biostatistical Genetics and Genetic Epidemiology PDF Author: Robert C. Elston
Publisher: John Wiley & Sons
ISBN: 9780471486312
Category : Medical
Languages : en
Pages : 860

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Book Description
Human Genetics concerns the study of genetic forces in man. By studying our genetic make-up we are able to understand more about our heritage and evolution. Some of the original, and most significant research in genetics centred around the study of the genetics of complex diseases - genetic epidemiology. This is the third in a highly successful series of books based on articles from the Encyclopedia of Biostatistics. This volume will be a timely and comprehensive reference, for a subject that has seen a recent explosion of interest following the completion of the first draft of the Human Genome Mapping Project. The editors have updated the articles from the Human Genetics section of the EoB, have adpated other articles to give them a genetic feel, and have included a number of newly commissioned articles to ensure the work is comprehensive and provides a self-contained reference.