Author: F. Lehmann-Grube
Publisher: Springer Science & Business Media
ISBN: 370918276X
Category : Medical
Languages : en
Pages : 306
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Book Description
I. Introduction Of the ever increasing number of viruses known to affect man and higher animals, the virus of lymphocytic choriomeningitis (LCM) was one of the first to be discovered. Indeed, this virus has been known and maintained in the laboratory by passages in a relatively simple host, the mouse, for 35 years. Yet our knowl edge of its properties is still scanty when compared with the wealth of informa tion available for other viruses, some of which have come to our attention much more recently. There are at least four reasons which may help to explain this seeming paradox. (1) The early belief that the LCM virus was the frequent cause of human diseases had soon to be abandoned; infections of man with this virus are rare. (2) By way of contrast, laboratory infections are not uncommon and they frequently run severe and even fatal courses. (3) Until recently, the only means of titrating the virus was by mouse inoculation, a method in which accuracy and economy are poorly correlated. (4) The virus is of unusual lability, being quickly inactivated under conditions which leave other viruses intact. Thus, when balancing medical and theoretical importance against personal hazard and tech nical difficulties, the result was quite unfavorable, and lack of interest was really not surprising. In the last few years, however, the situation has gradually changed and an increasing number of workers have turned their attention to this virus.
Author: F. Lehmann-Grube
Publisher: Springer
ISBN: 9783211810170
Category : Medical
Languages : en
Pages : 176
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Book Description
I. Introduction Of the ever increasing number of viruses known to affect man and higher animals, the virus of lymphocytic choriomeningitis (LCM) was one of the first to be discovered. Indeed, this virus has been known and maintained in the laboratory by passages in a relatively simple host, the mouse, for 35 years. Yet our knowl edge of its properties is still scanty when compared with the wealth of informa tion available for other viruses, some of which have come to our attention much more recently. There are at least four reasons which may help to explain this seeming paradox. (1) The early belief that the LCM virus was the frequent cause of human diseases had soon to be abandoned; infections of man with this virus are rare. (2) By way of contrast, laboratory infections are not uncommon and they frequently run severe and even fatal courses. (3) Until recently, the only means of titrating the virus was by mouse inoculation, a method in which accuracy and economy are poorly correlated. (4) The virus is of unusual lability, being quickly inactivated under conditions which leave other viruses intact. Thus, when balancing medical and theoretical importance against personal hazard and tech nical difficulties, the result was quite unfavorable, and lack of interest was really not surprising. In the last few years, however, the situation has gradually changed and an increasing number of workers have turned their attention to this virus.
Author:
Publisher: ScholarlyEditions
ISBN: 1464916055
Category : Medical
Languages : en
Pages : 19
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Book Description
Lymphocytic Choriomeningitis Virus: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Lymphocytic Choriomeningitis Virus in a compact format. The editors have built Lymphocytic Choriomeningitis Virus: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Lymphocytic Choriomeningitis Virus in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lymphocytic Choriomeningitis Virus: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Stephen N J Korsman
Publisher: Elsevier Health Sciences
ISBN: 1455742139
Category : Medical
Languages : en
Pages : 149
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Book Description
This is a concise, highly accessible introduction to medical virology, incorporating essential basic principles as well as a systematic review of viruses and viral diseases. It pays particular attention to developments in anti-viral therapy that are becoming increasingly effective in modern medicine. It is an ideal textbook for the information-overloaded student and an invaluable everyday companion for the busy professional who needs a good understanding of the current state of medical virology. In keeping with the highly successful format of other Illustrated Colour Texts, it presents the subject as a series of succinct 2 page 'learning units', using a superb collection of clear illustrations and clinical photographs, concise yet comprehensive text and key point boxes to aid quick access to information and examination preparation. So whether you are a medical student, junior doctor, medical scientist, trainee in infectious diseases or student on another allied medical course, this book is here to make your life easier! It will also provide a very solid foundation for any who plan to delve deeper into this fascinating field. - Part of the popular Illustrated Colour Text series - Information presented in double page spreads for easy learning - Highly illustrated with both full colour graphics and clinical photographs - Each spread includes a key point box for exam preparation
Author: Fritz Lehmann-Grube
Publisher:
ISBN: 9783642656828
Category :
Languages : en
Pages : 358
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Book Description
Author: Joann Colville
Publisher: Elsevier Health Sciences
ISBN: 0323070922
Category : Medical
Languages : en
Pages : 264
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Book Description
This essential, authoritative handbook provides clear, accurate coverage of zoonoses — diseases that can spread from animals to humans. The consistent format helps you quickly locate key information, such as how each disease affects the host, how it is spread, how it is treated, and necessary safety precautions. It also discusses the importance of educating animal owners about the public health implications of zoonoses and how to prevent them from spreading. - Clear, concise coverage helps you respond quickly when presented with diseases that could potentially spread between patients, clients, and staff in the veterinary clinic. - Each disease entry begins with a chart of its potential morbidity (the rate of incidence of a disease) and mortality (death rate), giving you at-a-glance access to the chance of contracting the disease and the severity of the disease if contracted. - Clinically relevant coverage includes information on the etiology (bacterial, viral, parasitic, etc.), most common nonhuman hosts, transmission modes, course of the disease, clinical signs in animals and humans, diagnostic tests, prevention, and general advice. - Essential information on preventing the spread of disease helps you educate clients about how to protect themselves and their animals from zoonoses. - Coverage of diseases such as mad cow disease, West Nile virus, rabies, and anthrax, prepares you to answer client questions about diseases that are in the public eye.
Author:
Publisher: ScholarlyEditions
ISBN: 1464981612
Category : Medical
Languages : en
Pages : 26
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Book Description
Lymphocytic Choriomeningitis Virus: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Lymphocytic Choriomeningitis Virus in a compact format. The editors have built Lymphocytic Choriomeningitis Virus: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Lymphocytic Choriomeningitis Virus in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lymphocytic Choriomeningitis Virus: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Fritz Lehmann-Grube
Publisher: Springer Science & Business Media
ISBN: 3642656811
Category : Medical
Languages : de
Pages : 460
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Book Description
Four decades ago, lymphocytic choriomeningitis virus was discovered, at about the same time and independently, in 3 different localities in the U.S.A. Armstrong and Lillie encountered the agent in a monkey when they passaged a recent isolate of the St. Louis encephalitis virus; Rivers and Scott isolated 5 strains from patients with meningitis; and Traub revealed the virus in a colony of albino mice. Already in these first isolations mice were incriminated, and later observa tions proved beyond doubt that M. musculus is the principal reservoir of the virus in nature. For some time LCM virus was regarded as the sole etiologic agent of Wallgren's "meningite aseptique aigue". Soon, however, it became clear that Wallgren's syndrome had a multitude of causes, among which the LCM virus was of little relevance, and in subsequent years it disappeared from the sight of most viro logists. Indeed, it might have fallen into oblivion had it not been for Erich Traub who, practically all by himself, continued to investigate the intricate relationship between this virus and its natural host, the common house mouse.
Author: M.B.A. Oldstone
Publisher: Springer Science & Business Media
ISBN: 3642560296
Category : Medical
Languages : en
Pages : 322
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Book Description
Since the subject of arenaviruses was visited by Current Topics in Microbiology and Immunology 14 years ago, enormous advances have been made in this area. The receptor for several arenaviruses, alpha-dystroglycan, was identified, the replication strategy of these viruses was decoded, and application of a reverse genetics system for studying viral gene function and viral biology is well underway. In addition to reviewing these advances, Volume I includes discussion of arenaviral molecular phylogeny, reservoirs in rodents and clinical diseases caused by both new world and old world arenaviruses.
Author: Carol Shoshkes Reiss
Publisher: Springer
ISBN: 3319331892
Category : Medical
Languages : en
Pages : 562
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Book Description
This second edition is a comprehensive study of the viruses that affect the brain and the central nervous system. Along with a focus on the viruses themselves, it addresses the diseases they cause, current treatments and preventive measures. Also discussed are the unique aspects of how viruses cause disease and why certain hosts are more susceptible (e.g., polymorphisms, age, co-morbidities). Because there are 29 cutting edge chapters, written by experts in the fields, Neurotropic Viral Infections has been divided into two separate volumes. Volume 1, Neurotropic RNA Viruses, includes 14 chapters on RNA viruses that cause human disease of the central nervous system ranging from Bornavirus to polio to West Nile. Volume 2, Neurotropic Retroviruses, DNA Viruses, Immunity and Transmission, includes 15 chapters divided into two parts. Part 1 includes 7 chapters on retroviruses and DNA viruses that cause human disease of the central nervous system ranging from HIV to varicella zoster virus. Part 2 includes chapters on transmission of these viruses by transplantation, bites by bats and insects, clinical management of the infections, and beneficial uses of attenuated viruses. Neurotropic Viral Infections is a unique resource, bridging basic, clinical, and translational approaches.
