Immunotherapy in Asthma

Immunotherapy in Asthma PDF Author: Jean Bousquet
Publisher: CRC Press
ISBN: 9780824701765
Category : Medical
Languages : en
Pages : 0

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Book Description
This massive reference thoroughly analyzes the mechanisms implicated in the pathophysiology of asthma, such as T helper lymphocyte subsets, and the consequences of various extrinsic and intrinsic factors, and IgE receptor expression-reviewing current concepts in immunotherapeutic approaches for the treatment of this and other allergic diseases. Investigates the only category of treatment showing the potential to affect the natural course of allergic diseases and prevent the onset of asthma. Written by more than 80 internationally renowned pulmonary experts, allergic disease specialists, and basic researchers, Immunotherapy in Asthma discusses the efficacy of new medications examines the role of metachromatic cells, lymphocytes, macrophages, and other cell types present in bronchial biopsies presents basic topics such as the functional and phenotypic properties of Th1 and Th2 cells and their role in allergic disease and the regulation of IgE-mediated inflammatory responses addresses the deleterious effects of smoking and passive exposure to cigarette smoke in children and adults assesses differences and similarities between intrinsic and antigen-induced asthma describes the effects of immunogenic peptides on the cytokine production profile of allergen-specific CD4+ T cells explains the different clinical aspects of allergic responses, such as bronchial hyperreactivity and eosinophilic inflammation of the airways reviews the genetic basis of allergy, as well as risk factors for asthma explores oral, sublingual, local nasal, and local bronchial routes for noninjective immunotherapies evaluates various agents with modulatory effects on normal and pathogenic immune responses focuses on strategies for the prevention of childhood asthma and more! Containing over 3000 references, drawings, and tables, Immunotherapy in Asthma is an indispensable resource for pulmonologists, immunologists, allergists, and medical school students in these disciplines.

Immunotherapy in Asthma

Immunotherapy in Asthma PDF Author: Jean Bousquet
Publisher: CRC Press
ISBN: 9780824701765
Category : Medical
Languages : en
Pages : 0

Get Book Here

Book Description
This massive reference thoroughly analyzes the mechanisms implicated in the pathophysiology of asthma, such as T helper lymphocyte subsets, and the consequences of various extrinsic and intrinsic factors, and IgE receptor expression-reviewing current concepts in immunotherapeutic approaches for the treatment of this and other allergic diseases. Investigates the only category of treatment showing the potential to affect the natural course of allergic diseases and prevent the onset of asthma. Written by more than 80 internationally renowned pulmonary experts, allergic disease specialists, and basic researchers, Immunotherapy in Asthma discusses the efficacy of new medications examines the role of metachromatic cells, lymphocytes, macrophages, and other cell types present in bronchial biopsies presents basic topics such as the functional and phenotypic properties of Th1 and Th2 cells and their role in allergic disease and the regulation of IgE-mediated inflammatory responses addresses the deleterious effects of smoking and passive exposure to cigarette smoke in children and adults assesses differences and similarities between intrinsic and antigen-induced asthma describes the effects of immunogenic peptides on the cytokine production profile of allergen-specific CD4+ T cells explains the different clinical aspects of allergic responses, such as bronchial hyperreactivity and eosinophilic inflammation of the airways reviews the genetic basis of allergy, as well as risk factors for asthma explores oral, sublingual, local nasal, and local bronchial routes for noninjective immunotherapies evaluates various agents with modulatory effects on normal and pathogenic immune responses focuses on strategies for the prevention of childhood asthma and more! Containing over 3000 references, drawings, and tables, Immunotherapy in Asthma is an indispensable resource for pulmonologists, immunologists, allergists, and medical school students in these disciplines.

Local Immunotherapy in Allergy

Local Immunotherapy in Allergy PDF Author: Udo R. Markert
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805575319
Category : Health & Fitness
Languages : en
Pages : 153

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Book Description
The incidence of allergies is increasing worldwide. Beside the well-established symptomatic treatments and subcutaneous immunotherapies, formerly known as de- or hyposensitization, a new form of treatment, local immunotherapy, has been developed in recent years. Local immunotherapy, though still controversially discussed, promises to be a curative, noninvasive, and easily applicable treatment for allergies. This volume summarizes the most current information on local immunotherapy compiled by internationally renowned specialists. In the methodology section, general aspects of local immunotherapy are presented including its history, allergen resorption and biodistribution, mechanisms of oral tolerance and practical experiences. The second section devoted to efficacy and safety presents findings from international placebo-controlled studies on nasal and sublingual immunotherapies with different allergens and for different allergic conditions including asthma and eczema. Possible side effects are also discussed. The concluding chapter critically evaluates the future prospects of this new method, pointing out still unresolved issues such as the exact immunological mechanisms, its long-term effects, or the standardization of dose and application intervals/duration. This state-of-the-art account will be of particular interest to scientists working in the field of allergy, clinical allergologists, pharmacists, and representatives from the pharmaceutical industry.

Mechanisms of Immune Regulation

Mechanisms of Immune Regulation PDF Author: Richard D. Granstein
Publisher: S. Karger AG (Switzerland)
ISBN:
Category : Medical
Languages : en
Pages : 360

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Book Description
Among the topics reviewed are T and B cell tolerance, clonal deletion, suppressor cells, mechanisms of immune privileged sites and experimental models of tumor immunity. Oral tolerance, ultraviolet radiation and photosensitized effects on immunity, allograft management, T cell vaccination and regulation of immunity with T cell epitopes are discussed from the point of view of possible therapeutic application.

The End of Food Allergy

The End of Food Allergy PDF Author: Kari Nadeau MD, PhD
Publisher: Penguin
ISBN: 0593189523
Category : Health & Fitness
Languages : en
Pages : 354

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Book Description
A life-changing, research-based program that will end food allergies in children and adults forever. The problem of food allergy is exploding around us. But this book offers the first glimpse of hope with a powerful message: You can work with your family and your doctor to eliminate your food allergy forever. The trailblazing research of Dr. Kari Nadeau at Stanford University reveals that food allergy is not a life sentence, because the immune system can be retrained. Food allergies--from mild hives to life-threatening airway constriction--can be disrupted, slowed, and stopped. The key is a strategy called immunotherapy (IT)--the controlled, gradual reintroduction of an allergen into the body. With innovations that include state-of-the-art therapies targeting specific components of the immune system, Dr. Nadeau and her team have increased the speed and effectiveness of this treatment to a matter of months. New York Times bestselling author Sloan Barnett, the mother of two children with food allergies, provides a lay perspective that helps make Dr. Nadeau's research accessible for everyone. Together, they walk readers through every aspect of food allergy, including how to find the right treatment and how to manage the ongoing fear of allergens that haunts so many sufferers, to give us a clear, supportive plan to combat a major national and global health issue.

Patterson's Allergic Diseases

Patterson's Allergic Diseases PDF Author: Leslie C. Grammer
Publisher: Lippincott Williams & Wilkins
ISBN: 1451148631
Category : Medical
Languages : en
Pages : 736

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Book Description
Revised and updated for its Seventh Edition, this highly acclaimed volume is a complete, current, and practical guide to the diagnosis and treatment of allergic disorders. This comprehensive yet concise reference will remain the first choice for residents and practitioners who need guidance to identify an allergy, confirm a diagnosis, or find effective therapies. It will also be an excellent aid for board review. This edition includes discussions of clinical trials in asthma and significant updates on drug allergy, imaging, occupational allergy, and immune deficiency evaluation. A Companion Website will include the fully searchable text and additional illustrations and tables.

Finding a Path to Safety in Food Allergy

Finding a Path to Safety in Food Allergy PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309450314
Category : Medical
Languages : en
Pages : 575

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Book Description
Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.

Textbook of Allergy for the Clinician

Textbook of Allergy for the Clinician PDF Author: Pudupakkam K. Vedanthan
Publisher: CRC Press
ISBN: 1000280721
Category : Medical
Languages : en
Pages : 635

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Book Description
This is the second and updated version of the Textbook of Allergy for the Clinician. It is a unique book in the field of allergy. The uniqueness lies in the international character of the book with contributors representing both the East and West. This book represents the diversity of issues affecting patients in the specialty of allergy, asthma & immunology. There is some discussion of the basic mechanisms involved and extensive elaboration for the clinicians. This book will appeal to medical students, residents and fellows undergoing training as well as consultants in academic and clinical practice settings. The color plates, especially in the section on Aerobiology, will help in the interaction between the patient and consultant in identifying the plant or flora which is the causative factor. The differences and similarities between the Eastern and Western approaches in the practice of the specialty are being addressed for the first time in a book.

Drug Allergy Testing

Drug Allergy Testing PDF Author: David Khan
Publisher: Elsevier Health Sciences
ISBN: 0323497071
Category : Medical
Languages : en
Pages : 289

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Book Description
With a focus on improving diagnosis and treatment, Drug Allergy Testing is your new go-to resource for understanding various drug allergies and testing methods, the epidemiology of and economic impact of drug allergies, and new drug and allergy developments. - Features a wealth of up-to-date information for allergists, immunologists, and primary care physicians who diagnose and treat patients with drug allergies and hypersensitivity. - Covers the basics of drug allergy evaluation and management as well as specific drugs including antibiotics, ASA/NSAIDs, chemotherapeutic agents and monoclonal antibodies.

ABC of Allergies

ABC of Allergies PDF Author: Stephen R. Durham
Publisher: BMJ Books
ISBN: 9781405139588
Category : Medical
Languages : en
Pages : 0

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Book Description
The ABC of Allergies is a thorough and practical guide to the treatment and diagnosis of allergies. Now in its second edition, this fully revised and updated text contains information about all major allergies, including food allergies, adverse drug reactions, venom allergy, anaphylaxis and hay fever. Asthma, rhinitis and allergic skin and eye diseases are also covered in great depth and there are new chapters on latex allergy, allergy to local and general anaesthetic drugs and allergen immunotherapy.Written by internationally acclaimed experts, the ABC of Allergies will prove invaluable to general practitioners and practice nurses and will be a perfect reference for immunologists and basic scientists working in this area. It is also an ideal teaching resource.

Practical Insights into Atopic Dermatitis

Practical Insights into Atopic Dermatitis PDF Author: Kwang Hoon Lee
Publisher: Springer Nature
ISBN: 9811581592
Category : Medical
Languages : en
Pages : 240

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Book Description
This book is a comprehensive, practical guide to the latest developments in the understanding and management of atopic dermatitis. Detailed information is provided on age-specific clinical symptoms, features, and diagnostic methods. Current theories on the pathogenesis of atopic dermatitis are closely examined, with attention to the roles played by genetic, allergic, immunologic, and skin barrier dysfunctions. In the second half of the book, the scientific background to and the practical use of the full range of treatment methods are described, covering topical agents, systemic agents, phototherapy, allergen-specific immunotherapy, and the most recently developed biologics and small molecules. This textbook will be an excellent guide to diagnosis and treatment for not only dermatologists but also practitioners in allergy and general medicine, including pediatricians, allergists, and primary care physicians. In addition, it will be of value for all scientists interested in developing new drugs for atopic dermatitis.