Regulation of Tissue Oxygenation, Second Edition

Regulation of Tissue Oxygenation, Second Edition PDF Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117

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Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Regulation of Tissue Oxygenation, Second Edition

Regulation of Tissue Oxygenation, Second Edition PDF Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117

Get Book Here

Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Strategies to Improve Cardiac Arrest Survival

Strategies to Improve Cardiac Arrest Survival PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030937202X
Category : Medical
Languages : en
Pages : 291

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Book Description
Cardiac arrest can strike a seemingly healthy individual of any age, race, ethnicity, or gender at any time in any location, often without warning. Cardiac arrest is the third leading cause of death in the United States, following cancer and heart disease. Four out of five cardiac arrests occur in the home, and more than 90 percent of individuals with cardiac arrest die before reaching the hospital. First and foremost, cardiac arrest treatment is a community issue - local resources and personnel must provide appropriate, high-quality care to save the life of a community member. Time between onset of arrest and provision of care is fundamental, and shortening this time is one of the best ways to reduce the risk of death and disability from cardiac arrest. Specific actions can be implemented now to decrease this time, and recent advances in science could lead to new discoveries in the causes of, and treatments for, cardiac arrest. However, specific barriers must first be addressed. Strategies to Improve Cardiac Arrest Survival examines the complete system of response to cardiac arrest in the United States and identifies opportunities within existing and new treatments, strategies, and research that promise to improve the survival and recovery of patients. The recommendations of Strategies to Improve Cardiac Arrest Survival provide high-priority actions to advance the field as a whole. This report will help citizens, government agencies, and private industry to improve health outcomes from sudden cardiac arrest across the United States.

Braunwald's Heart Disease E-Book

Braunwald's Heart Disease E-Book PDF Author: Douglas L. Mann
Publisher: Elsevier Health Sciences
ISBN: 0323290647
Category : Medical
Languages : en
Pages : 2376

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Book Description
Ideal for cardiologists who need to keep abreast of rapidly changing scientific foundations, clinical research results, and evidence-based medicine, Braunwald’s Heart Disease is your indispensable source for definitive, state-of-the-art answers on every aspect of contemporary cardiology, helping you apply the most recent knowledge in personalized medicine, imaging techniques, pharmacology, interventional cardiology, electrophysiology, and much more! Practice with confidence and overcome your toughest challenges with advice from the top minds in cardiology today, who synthesize the entire state of current knowledge and summarize all of the most recent ACC/AHA practice guidelines. Locate the answers you need fast thanks to a user-friendly, full-color design with more than 1,200 color illustrations. Learn from leading international experts, including 53 new authors. Explore brand-new chapters, such as Principles of Cardiovascular Genetics and Biomarkers, Proteomics, Metabolomics, and Personalized Medicine. Access new and updated guidelines covering Diseases of the Aorta, Peripheral Artery Diseases, Diabetes and the Cardiovascular System, Heart Failure, and Valvular Heart Disease. Stay abreast of the latest diagnostic and imaging techniques and modalities, such as three-dimensional echocardiography, speckle tracking, tissue Doppler, computed tomography, and cardiac magnetic resonance imaging. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.

Living Without Limits

Living Without Limits PDF Author: Judy Siegle
Publisher: InterVarsity Press
ISBN: 0830856978
Category : Biography & Autobiography
Languages : en
Pages : 193

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Book Description
A two-time Paralympian shares her story challenging readers to new perspectives in living life to the fullest.

Two-Dimensional People

Two-Dimensional People PDF Author: Tan Tongxue
Publisher: Taylor & Francis
ISBN: 1000813452
Category : Social Science
Languages : en
Pages : 315

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Book Description
Based on almost eight years of fieldwork in a town and a village in South China, this book analyzes contradictions among various dimensions of the peasant economy, social relationships, popular religion, and local politics in rural China. Compared to many anthropological, sociological, and political studies of rural China, which regard Chinese peasants as one-dimensionally materialistic, politically conservative, egocentric (lacking public-mindedness, as in anthropologist Yan Yunxiang’s notion of the "uncivil individual"), with collapsed beliefs, and thinking only of the present (or the "today-ness of today" according to anthropologist Liu Xin), this book shows that people in contemporary rural China are actually "two-dimensional": trying to combine the calculation of self-interest with affective networks of reciprocity, but often falling into awkwardness or cynicism, in a paradoxical symbiosis between nihilism and transcendence. While Marcuse used the words of Benjamin to analyze "one-dimensional man," writing "Only for the sake of the hopeless ones have we been given hope," this book writes of two-dimensional people, "Only when the vast majority of ordinary people can find hope in everyday life can we finally be given hope!" This book will be of interest to scholars and students of Sociology, Anthropology and East Asian Studies. It will also be a great read to those who are interested in contemporary China in general.

My Teenage Zombie

My Teenage Zombie PDF Author: David L. Henderson
Publisher: Thomas Nelson
ISBN: 071803127X
Category : Religion
Languages : en
Pages : 257

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Book Description
A must-read guide for parents and grandparents who want to practically and successfully help their teenager navigate the ever-lengthening stage of adolescence launching them into society with confidence, vision, and success. Zombies are not just found in horror movies, sometimes they’re lying on your living room couch. These are undead adolescents whose psychological and social development has come to a screeching halt. Torn by their yearning for freedom and their fear of surviving the outside world, they have stalled in their maturity, motivation, and purpose in life, hijacked by a helplessness and fear of responsibility. Parents often feel ill-equipped to love, support, and guide them—especially when they may be facing a midlife crisis of their own and battling some of the same issues in their own lives. Is it really possible to escape this “undead” state of being? In My Teenage Zombie board-certified psychiatrist and medical doctor David L. Henderson explains the parts of a teenage zombie (their brain, heart, and spirit), how they got into this undead state, and how to resurrect them back to life. Using real-life examples of families he has counseled, he describes both their physical and psychological characteristics and offers practical suggestions on how to deal with, and in many cases avoid, having an undead adolescent in your home.

Swimming With the Whale - Second Edition

Swimming With the Whale - Second Edition PDF Author: Daniel Joseph
Publisher: Uriel Publishing Group
ISBN: 1311880364
Category : Body, Mind & Spirit
Languages : en
Pages : 330

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Book Description


Pulse

Pulse PDF Author: Jeremy Robinson
Publisher: Macmillan
ISBN: 1429986441
Category : Fiction
Languages : en
Pages : 416

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Book Description
HOW MANY PEOPLE WOULD YOU KILL TO LIVE FOREVER? Imagine a world where soldiers regenerate and continue fighting without pause, where suicide bombers live to strike again and again. This is the dream of Richard Ridley, founder of Manifold Genetics, and he has just discovered the key to eternal life: an ancient artifact buried beneath a Greek-inscribed stone in the Peruvian desert. When Manifold steals the artifact and abducts archeologist Dr. George Pierce, United States Special Forces Delta operator Jack Sigler, call sign King, and his "Chess Team" —Queen, Knight, Rook, Bishop, and their handler, Deep Blue—give chase. Formed under special order from President Duncan, they are the best of America's Special Forces, tasked with antiterrorism missions that take them around the world against any threat, ancient, modern, and at times, inhuman. With cutting-edge weapons, tough-as-nails tactics, and keen intellects, they stand alone on the brink, facing the world's most dangerous threats. Ridley's plan to create unstoppable soldiers has just made him threat number one. Tension soars along with the body count as the team faces high-tech security forces, hordes of "regens," the horrific results of Manifold's experiments, and a resurrected mythological predator complete with regenerative abilities, seven heads, and a savage appetite. The Chess Team races to save Pierce and stop Manifold before they change the face of genetics—and human history—forever. Heart-pounding action combines with adrenaline-charged suspense in the first of Jeremy Robinson's smart, sharp series featuring the Chess Team.

The Life and Letters of William Sharp and "Fiona Macleod". Volume 2: 1895-1899

The Life and Letters of William Sharp and Author: William F. Halloran
Publisher: Open Book Publishers
ISBN: 1783748729
Category : Biography & Autobiography
Languages : en
Pages : 369

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Book Description
What an achievement! It is a major work. The letters taken together with the excellent introductory sections - so balanced and judicious and informative - what emerges is an amazing picture of William Sharp the man and the writer which explores just how fascinating a figure he is. Clearly a major reassessment is due and this book could make it happen.  —Andrew Hook, Emeritus Bradley Professor of English and American Literature, Glasgow University William Sharp (1855-1905) conducted one of the most audacious literary deceptions of his or any time. Sharp was a Scottish poet, novelist, biographer and editor who in 1893 began to write critically and commercially successful books under the name Fiona Macleod. This was far more than just a pseudonym: he corresponded as Macleod, enlisting his sister to provide the handwriting and address, and for more than a decade "Fiona Macleod" duped not only the general public but such literary luminaries as William Butler Yeats and, in America, E. C. Stedman. Sharp wrote "I feel another self within me now more than ever; it is as if I were possessed by a spirit who must speak out". This three-volume collection brings together Sharp’s own correspondence – a fascinating trove in its own right, by a Victorian man of letters who was on intimate terms with writers including Dante Gabriel Rossetti, Walter Pater, and George Meredith – and the Fiona Macleod letters, which bring to life Sharp’s intriguing "second self". With an introduction and detailed notes by William F. Halloran, this richly rewarding collection offers a wonderful insight into the literary landscape of the time, while also investigating a strange and underappreciated phenomenon of late-nineteenth-century English literature. It is essential for scholars of the period, and it is an illuminating read for anyone interested in authorship and identity.

The Checklist Manifesto

The Checklist Manifesto PDF Author: Atul Gawande
Publisher: Metropolitan Books
ISBN: 1429953381
Category : Medical
Languages : en
Pages : 225

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Book Description
The New York Times bestselling author of Being Mortal and Complications reveals the surprising power of the ordinary checklist We live in a world of great and increasing complexity, where even the most expert professionals struggle to master the tasks they face. Longer training, ever more advanced technologies—neither seems to prevent grievous errors. But in a hopeful turn, acclaimed surgeon and writer Atul Gawande finds a remedy in the humblest and simplest of techniques: the checklist. First introduced decades ago by the U.S. Air Force, checklists have enabled pilots to fly aircraft of mind-boggling sophistication. Now innovative checklists are being adopted in hospitals around the world, helping doctors and nurses respond to everything from flu epidemics to avalanches. Even in the immensely complex world of surgery, a simple ninety-second variant has cut the rate of fatalities by more than a third. In riveting stories, Gawande takes us from Austria, where an emergency checklist saved a drowning victim who had spent half an hour underwater, to Michigan, where a cleanliness checklist in intensive care units virtually eliminated a type of deadly hospital infection. He explains how checklists actually work to prompt striking and immediate improvements. And he follows the checklist revolution into fields well beyond medicine, from disaster response to investment banking, skyscraper construction, and businesses of all kinds. An intellectual adventure in which lives are lost and saved and one simple idea makes a tremendous difference, The Checklist Manifesto is essential reading for anyone working to get things right.