Long Circulating Liposomes: Old Drugs, New Therapeutics

Long Circulating Liposomes: Old Drugs, New Therapeutics PDF Author: Martin C. Woodle
Publisher: Springer Science & Business Media
ISBN: 3662221152
Category : Medical
Languages : en
Pages : 327

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Book Description
This book provides an up-to-date evaluation of clinical aspects of newly available "long-circulating liposome" formulations. Based on results from numerous clinical studies, the book describes the fundamentals of this new technology, discusses how it may influence the pharmacology of existing well-known agents reformulated in this manner, and elaborates on future expectations. It provides the practicing clinician - in particular, oncologists and critical care infectious disease physicians - with the tools needed to use these new formulations towards the best outcome for the patient.

Liposomes in Drug Delivery

Liposomes in Drug Delivery PDF Author: AlexanderT. Florence
Publisher: Routledge
ISBN: 1351435043
Category : Medical
Languages : en
Pages : 278

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Book Description
First Published in 2017. Routledge is an imprint of Taylor & Francis, an Informa company.

Liposomes, Part A

Liposomes, Part A PDF Author: Nejat Duzgunes
Publisher: Elsevier
ISBN: 008049708X
Category : Science
Languages : en
Pages : 345

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Book Description
Liposomes are cellular structures made up of lipid molecules. Important as a cellular model in the study of basic biology, liposomes are also used in clinical applications such as drug delivery and virus studies. - Methods in Liposome Preparation - Physiochemical Characterization of Liposomes

Liposomes

Liposomes PDF Author: Angel Catala
Publisher: BoD – Books on Demand
ISBN: 1789844940
Category : Science
Languages : en
Pages : 104

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Book Description
Liposomes have received increased attention in recent years. Nevertheless, liposomes, due to their various forms and applications, require further investigation. These structures can deliver both hydrophilic and hydrophobic drugs. The preparation of liposomes results in different properties for these systems. In addition, there are many factors and difficulties that affect the development of liposome drug delivery structures.The purpose of this book is to concentrate on recent developments in liposomes. The articles collected in this book are contributions by invited researchers with long-standing experience in different research areas. We hope that the material presented here is understandable to a broad audience, not only scientists but also people with a general background in many different biological sciences. This volume offers up-to-date, expert reviews of the fast-moving field of liposomes and is divided in two major sections: 1. Introduction; 2. Liposomes general properties

Liposome-Based Drug Delivery Systems

Liposome-Based Drug Delivery Systems PDF Author: Wan-Liang Lu
Publisher: Springer
ISBN: 9783662493182
Category : Technology & Engineering
Languages : en
Pages : 0

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Book Description
This volume describes the protocols for fabrication of liposomal drug delivery system, and consists of two parts. The first part emphasizes the basic protocols and concepts for fabrication of drug-loaded liposomes. For new investigators, laying the groundwork is the first step. This part focuses on the fabrication details in liposomes formulations, which are the so-called small tricks while usually not disclosed in mostly published research articles. However, these processing details are crucial for the preparation of liposomes. And the second part focuses on the strategies in modified and/or functionalized liposomes to adapt to pathophysiological environment, as well as their application in treating diseases. As new analytical and synthetic technologies become available, and improved understanding of pathophysiology, various functionalized drug liposomes are developing to fit the requirements of different therapeutic purposes, exhibiting a broad range of applications. Accordingly, the objectives of this part are aimed at deeply unearthing the formulation of drug-loaded liposomes, describing the detailed operation of liposomal formulation, and further demonstrating their potential applications. Therefore, this volume shows the features of experimental report or protocol for proving a guide to scientists, research students, and young investigators in pharmaceutical enterprises.

Liposomes, Lipid Bilayers and Model Membranes

Liposomes, Lipid Bilayers and Model Membranes PDF Author: Georg Pabst
Publisher: CRC Press
ISBN: 146650711X
Category : Medical
Languages : en
Pages : 470

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Book Description
As a result of their unique physical properties, biological membrane mimetics, such as liposomes, are used in a broad range of scientific and technological applications. Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application describes state-of-the-art research and future directions in the field of membranes, which has evo

Intracellular Delivery

Intracellular Delivery PDF Author: Aleš Prokop
Publisher: Springer Science & Business Media
ISBN: 9400712480
Category : Science
Languages : en
Pages : 871

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Book Description
This book features a special subsection of Nanomedicine, an application of nanotechnology to achieve breakthroughs in healthcare. It exploits the improved and often novel physical, chemical and biological properties of materials only existent at the nanometer scale. As a consequence of small scale, nanosystems in most cases are efficiently uptaken by cells and appear to act at the intracellular level. Nanotechnology has the potential to improve diagnosis, treatment and follow-up of diseases, and includes targeted drug delivery and regenerative medicine; it creates new tools and methods that impact significantly upon existing conservative practices. This volume is a collection of authoritative reviews. In the introductory section we define the field (intracellular delivery). Then, the fundamental routes of nanodelivery devices, cellular uptake, types of delivery devices, particularly in terms of localized cellular delivery, both for small drug molecules, macromolecular drugs and genes; at the academic and applied levels, are covered. The following section is dedicated to enhancing delivery via special targeting motifs followed by the introduction of different types of intracellular nanodelivery devices (e.g. a brief description of their chemistry) and ways of producing these different devices. Finally, we put special emphasis on particular disease states and on other biomedical applications, whilst diagnostic and sensing issues are also included. Intracellular delivery / therapy is a highly topical which will stir great interest. Intracellular delivery enables much more efficient drug delivery since the impact (on different organelles and sites) is intracellular as the drug is not supplied externally within the blood stream. There is great potential for targeted delivery with improved localized delivery and efficacy.

Bio-Applications of Nanoparticles

Bio-Applications of Nanoparticles PDF Author: Warren C.W. Chan
Publisher: Springer
ISBN: 9780387767123
Category : Medical
Languages : en
Pages : 207

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Book Description
This edited book highlights the central players in the Bionanotechnology field - which are the nanostructures and biomolecules. It provides broad examples of current developments in Bionanotechnology research and is an excellent introduction to the field. The book describes how nanostructures are synthesized and details the wide variety of nanostructures available for biological research and applications. Examples of the unique properties of nanostructures are provided along with the current applications of these nanostructures in biology and medicine. The final chapters of the book describe the toxicity of nanostructures.

Advanced Bacterial Genetics: Use of Transposons and Phage for Genomic Engineering

Advanced Bacterial Genetics: Use of Transposons and Phage for Genomic Engineering PDF Author:
Publisher: Elsevier
ISBN: 0080475108
Category : Science
Languages : en
Pages : 319

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Book Description
The critically acclaimed laboratory standard for more than fifty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. This new volume presents methods related to the use of bacterial genetics for genomic engineering. The book includes sections on strain collections and genetic nomenclature; transposons; and phage.

RNA Interference

RNA Interference PDF Author: David R. Engelke
Publisher: Elsevier
ISBN: 0080455395
Category : Science
Languages : en
Pages : 487

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Book Description
The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.RNA Interference will cover RNAi in non-vertebrates (plants, C. elegans, drosophila, and S. pombe), and Mammalian systems (human and non-human cells). This volume discusses extensive methodology related to delivery methods high throughput strategies and prospects as a human therapy agent.* One of the most highly respected publications in the field of biochemistry since 1955 * Frequently consulted, and praised by researchers and reviewers alike * Truly an essential publication for anyone in any field of the life sciences

Non-Natural Amino Acids

Non-Natural Amino Acids PDF Author:
Publisher: Academic Press
ISBN: 0080921639
Category : Science
Languages : en
Pages : 334

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Book Description
By combining the tools of organic chemistry with those of physical biochemistry and cell biology, Non-Natural Amino Acids aims to provide fundamental insights into how proteins work within the context of complex biological systems of biomedical interest. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. With more than 400 volumes published, each Methods in Enzymology volume presents material that is relevant in today's labs -- truly an essential publication for researchers in all fields of life sciences. - Demonstrates how the tools and principles of chemistry combined with the molecules and processes of living cells can be combined to create molecules with new properties and functions found neither in nature nor in the test tube - Presents new insights into the molecular mechanisms of complex biological and chemical systems that can be gained by studying the structure and function of non-natural molecules - Provides a "one-stop shop" for tried and tested essential techniques, eliminating the need to wade through untested or unreliable methods