Lead Compounds from Medicinal Plants for the Treatment of Cancer

Lead Compounds from Medicinal Plants for the Treatment of Cancer PDF Author: Christophe Wiart
Publisher: Academic Press
ISBN: 0123983711
Category : Health & Fitness
Languages : en
Pages : 430

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Book Description
Kelley/DNA Repair in Cancer Therapy, 2012, 978-0-12-384999-1.

Lead Compounds from Medicinal Plants for the Treatment of Cancer

Lead Compounds from Medicinal Plants for the Treatment of Cancer PDF Author: Christophe Wiart
Publisher: Academic Press
ISBN: 0123983711
Category : Health & Fitness
Languages : en
Pages : 430

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Book Description
Kelley/DNA Repair in Cancer Therapy, 2012, 978-0-12-384999-1.

Lead Molecules from Natural Products

Lead Molecules from Natural Products PDF Author:
Publisher: Elsevier
ISBN: 0080459331
Category : Science
Languages : en
Pages : 449

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Book Description
Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered.The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations.* Explains the effects of plant extracts on gene expression profiling. * Details medicinal plant research from around the world* Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents.

Plant Bioactives and Drug Discovery

Plant Bioactives and Drug Discovery PDF Author: Valdir Cechinel-Filho
Publisher: John Wiley & Sons
ISBN: 1118259920
Category : Science
Languages : en
Pages : 600

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Book Description
An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today. With coverage of strategic methods of natural compound isolation, structural manipulation, natural products in clinical trials, quality control, and more, and featuring case studies on medicinal plants, the book serves as a definitive guide to the field of plant biodiversity as it relates to medicine. In addition, chapters on using natural products as drugs that target specific disease areas, including neurological disorders, inflammation, infectious diseases, and cancer, illustrate the myriad possibilities for therapeutic applications. Wide ranging and comprehensive, Plant Bioactives and Drug Discovery also includes important information on marketing, regulations, intellectual property rights, and academic-industry collaboration as they relate to plant-based drug research, making it an essential resource for advanced students and academic and industry professionals working in biochemical, pharmaceutical, and related fields.

The Role of Natural Products in Drug Discovery

The Role of Natural Products in Drug Discovery PDF Author: J. Mulzer
Publisher: Springer Science & Business Media
ISBN: 3662040425
Category : Medical
Languages : en
Pages : 363

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Book Description
Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products. Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.

Anticancer Plants: Mechanisms and Molecular Interactions

Anticancer Plants: Mechanisms and Molecular Interactions PDF Author: Mohd Sayeed Akhtar
Publisher: Springer
ISBN: 9811084173
Category : Science
Languages : en
Pages : 365

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Book Description
This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. The book provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research.

Bioactive Compounds of Medicinal Plants

Bioactive Compounds of Medicinal Plants PDF Author: Megh R. Goyal
Publisher: CRC Press
ISBN: 1351376411
Category : Science
Languages : en
Pages : 234

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Book Description
This volume sheds new light on the immense potential of medicinal plants for human health from different technological aspects. It presents new research on bioactive compounds in medicinal plants that provide health benefits, including those that have proven especially effective in treating and managing diabetes mellitus and hypertension. It looks at the medicinal properties, antioxidant capacity, and antimicrobial activity of plants and provides scientific evidence on the use of medicinal plants in the treatment of certain diseases. Many of the plants described in the chapters are easily accessible and are believed to be effective with fewer side effects in comparison to modern drugs in the treatment of different diseases.

Natural Compounds in Cancer Therapy

Natural Compounds in Cancer Therapy PDF Author: John Boik
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 548

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Book Description
Natural Compounds in Cancer Therapy is a classic reference work for patients and medical professionals interested in use of nontoxic botanical compounds in the treatment of cancer. It offers a snapshot of the field circa 2001, and its insights are still pertinent today. Natural Compounds in Cancer Therapy is among the first books to discuss the use of natural products against cancer from a systems biology perspective.

Bioactive Compounds from Natural Sources, Second Edition

Bioactive Compounds from Natural Sources, Second Edition PDF Author: Corrado Tringali
Publisher: CRC Press
ISBN: 1439822298
Category : Science
Languages : en
Pages : 650

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Book Description
The first edition of Bioactive Compounds from Natural Sources was published in a period of renewed attention to biologically active compounds of natural origin. This trend has continued and intensified—natural products are again under the spotlight, in particular for their possible pharmacological applications. Largely focusing on natural products as lead compounds in drug discovery, Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug Discovery is actually a completely new volume containing surveys of selected recent advances in an interdisciplinary area covering chemistry of natural products, medicinal chemistry, biochemistry, and other related topics. Written by some of the most reputed scientists in the field, this second edition includes new chapters from authors who contributed to the first edition as well as many chapters compiled by new authors. Introducing the reader to strategies and methods in the search for bioactive natural products, this book covers topics including: Natural sources of bioactive compounds such as aquatic cyanobacteria, filamentous fungi, and tropical plants, The tremendous potentiality of metabolic engineering of natural products biosynthesis The contribution of emerging or developing technologies to the study of bioactive natural compounds, namely computational methods and circular dichroism The potential of natural or natural-derived compounds for specific therapeutic applications: treatment of viral diseases, regulation of hypoxia-inducible factor, antimalarials, modulation of angiogenesis, and antitumor and wound-healing activity Selected examples of natural product families and related synthetic analogues, namely polyphenols and campthotecins Compiled for researchers and Ph.D. students working in interdisciplinary fields, this book will also be appreciated by readers without a background in chemistry interested in bioactive natural products, their biological and pharmacological properties, and their possible use as chemopreventive or chemotherapeutic agents. Conversely, the biological and pharmacological data and methods are accessible by chemists.

Herbal Medicine

Herbal Medicine PDF Author: Iris F. F. Benzie
Publisher: CRC Press
ISBN: 1439807167
Category : Health & Fitness
Languages : en
Pages : 488

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Book Description
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Lead Compounds from Medicinal Plants for the Treatment of Cancer

Lead Compounds from Medicinal Plants for the Treatment of Cancer PDF Author: Christophe Wiart
Publisher: Academic Press
ISBN: 0123983827
Category : Medical
Languages : en
Pages : 429

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Book Description
Lead Compounds from Medicinal Plants for the Treatment of Cancer is the first volume in the series, Pharmaceutical Leads from Medicinal Plants. The plant species described in this reference have been carefully selected based on pharmacological evidence and represent today's most promising sources of natural products for the discovery of anti-cancer drugs. Containing references to primary source material, over a hundred botanical illustrations, a table of chemical structures and much more, this book is an essential starting point for cancer researchers and those involved in anti-cancer drug discovery helping you identify the best novel lead molecules for further anti-cancer drug development. - Provides a compilation of hundreds of medicinal plants from Europe, Asia, North and South America and Africa that contain prominent lead candidates for anti-cancer drug discovery - Contains primary source references and hundreds of the most relevant citations from the current literature for additional research - Offers cancer researchers and pharmaceutical scientists valuable tools such as chemical structures and promising pharmacological data to help them select the novel lead compounds that will best aid drug discovery.