Laughing Gas, Viagra, and Lipitor

Laughing Gas, Viagra, and Lipitor PDF Author: Jie Jack Li
Publisher: Oxford University Press
ISBN: 0199885281
Category : Science
Languages : en
Pages : 467

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Book Description
The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections. Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true. The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful.

Laughing Gas, Viagra, and Lipitor

Laughing Gas, Viagra, and Lipitor PDF Author: Jie Jack Li
Publisher: Oxford University Press
ISBN: 0199885281
Category : Science
Languages : en
Pages : 467

Get Book Here

Book Description
The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections. Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true. The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful.

Laughing Gas, Viagra, and Lipitor

Laughing Gas, Viagra, and Lipitor PDF Author: Jie Jack Li
Publisher: Oxford University Press
ISBN: 0195345762
Category : Science
Languages : en
Pages : 329

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Book Description
The stories behind drug discovery are fascinating, full of human and scientific interest. This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated them. History is replete with examples of breakthrough medicines that have saved millions of lives. Ether as an anesthetic by Morton; penicillin as an antibiotic by Fleming; and insulin as an anti-diabetic by Banting are just a few examples. The discoverers of these medicines are doubtlessly benefactors to mankind--for instance, without penicillin, 75% of us probably would not be alive because some of our parents or grandparents would have succumbed to infections. Dr. Jack Li, a medicinal chemist who is intimately involved with drug discovery, has assembled an astounding amount of facts and information behind important drugs through extensive literature research and interviews with many inventors of the drugs including Viagra and Lipitor. There have been many myths and inaccuracies associated with those legendary drugs. The inventors perspectives afforded this book an invaluable accuracy and insight because history is not history unless it is true. The text is supplemented by many anecdotes, pictures and postage stamps. Both specialist and layman will find Laughing Gas, Viagra, and Lipitor informative and entertaining. Students in chemistry, pharmacy, and medicine, workers in healthcare and high school science teachers will find this book most useful.

Top Drugs

Top Drugs PDF Author: Jie Jack Li
Publisher: Oxford University Press
ISBN: 0199362602
Category : Medical
Languages : en
Pages : 219

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Book Description
Drugs like Lipitor, Plavix, Taxol, and Zoloft are integral in today's medicinal world. These widely used products save lives and improve the quality of lives, playing a crucial role in everything from cholesterol management to cancer treatment. These advances in medicine were brought into existence after nuanced process of creation, featuring a wide range of chemical and pharmacological experimentation and discovery. Top Drugs: Their History, Pharmacology, and Synthesis provides an in-depth study on ten prominent drugs, outlining the chemistry behind each one's creation. Jie Jack Li, a medicinal chemist and an expert on drug discovery, offers a thorough analysis of the landscape of current drug development. The comprehensive text is divided by health issues, including cardiovascular, cancer, metabolic diseases, and infectious diseases. Each section features individual chapters on significant drugs, outlining the chemistry and history of the drug's discovery. Li begins each chapter with the product's history, providing necessary context. Li then proceeds to describe the mechanism of action, structure-activity relationship (SAR), bioavailability, metabolism, toxicology, the discovery route, and the process route. Top Drugs: Their History, Pharmacology, and Synthesis will acclimate students, scientists, and interested laypersons to the world of chemistry and drug discovery.

Triumph of the Heart

Triumph of the Heart PDF Author: Jie Jack Li
Publisher: OUP USA
ISBN: 0195323572
Category : Medical
Languages : en
Pages : 220

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Book Description
Prologue. 1. Cholesterol. 2. Genesis of Statins. 3. Merck's Triumph. 4. Discovery of Lipitor. 5. Development of Lipitor. 6. To Market, To Market. 7. Baycol, Crestor, and Drugs beyond Statins. 8. Reflections. Appendix. Trademarks of the Drugs. Bibliography and Notes. Index.

Blockbuster Drugs

Blockbuster Drugs PDF Author: Jie Jack Li
Publisher: Oxford University Press
ISBN: 0199737681
Category : Business & Economics
Languages : en
Pages : 238

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Book Description
"This book uses the cases of several landmark drugs to discuss the history of the pharmaceutical industry, and discusses what could be next"--Provided by publisher.

The SAGE Encyclopedia of Economics and Society

The SAGE Encyclopedia of Economics and Society PDF Author: Frederick F. Wherry
Publisher: SAGE Publications
ISBN: 150630088X
Category : Social Science
Languages : en
Pages : 1969

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Book Description
Economics is the nexus and engine that runs society, affecting societal well-being, raising standards of living when economies prosper or lowering citizens through class structures when economies perform poorly. Our society only has to witness the booms and busts of the past decade to see how economics profoundly affects the cores of societies around the world. From a household budget to international trade, economics ranges from the micro- to the macro-level. It relates to a breadth of social science disciplines that help describe the content of the proposed encyclopedia, which will explicitly approach economics through varied disciplinary lenses. Although there are encyclopedias of covering economics (especially classic economic theory and history), the SAGE Encyclopedia of Economics and Society emphasizes the contemporary world, contemporary issues, and society. Features: 4 volumes with approximately 800 signed articles ranging from 1,000 to 5,000 words each are presented in a choice of print or electronic editions Organized A-to-Z with a thematic Reader′s Guide in the front matter groups related entries Articles conclude with References & Future Readings to guide students to the next step on their research journeys Cross-references between and among articles combine with a thorough Index and the Reader′s Guide to enhance search-and-browse in the electronic version Pedagogical elements include a Chronology of Economics and Society, Resource Guide, and Glossary This academic, multi-author reference work will serve as a general, non-technical resource for students and researchers within social science programs who seek to better understand economics through a contemporary lens.

Every Molecule Tells a Story

Every Molecule Tells a Story PDF Author: Simon Cotton
Publisher: CRC Press
ISBN: 1439807744
Category : Medical
Languages : en
Pages : 261

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Book Description
Written by a seasoned teacher, speaker, and writer in the field of chemistry, this text serves to provide a guide to the chemicals that make life possible and enrich the senses, as well as those that endanger it. This text combines the science and history of certain molecules and deals with the chemistry of each substance in an interesting and easily understandable manner. Topics covered include substances found in air and water, food, hydrocarbons, acids and alkalis, natural killers, unnatural killers, destructive molecules, pleasure molecules, natural healers, man-made healers, giant molecules, and vitamins.

Ten Drugs

Ten Drugs PDF Author: Thomas Hager
Publisher: Abrams
ISBN: 1683355318
Category : Medical
Languages : en
Pages : 342

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Book Description
“The stories are skillfully told and entirely entertaining . . . An expert, mostly feel-good book about modern medicine” from the award-winning author (Kirkus Reviews, starred review). Behind every landmark drug is a story. It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine. Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book. “[An] absorbing new book.” —The New York Times Book Review “[A] well-written and engaging chronicle.” —The Wall Street Journal “Lucidly informative and compulsively readable.” —Publishers Weekly “Entertaining [and] insightful.” —Booklist “Well-written, well-researched and fascinating to read Ten Drugs provides an insightful look at how drugs have shaped modern medical practices. Towards the end of the book Hager writes that he ‘came away surprised by some of the things he had learned.’ I had the very same reaction.” —Penny Le Couteur, coauthor of Napoleon’s Buttons: How 17 Molecules Changed History

The Story of Pharmaceuticals

The Story of Pharmaceuticals PDF Author: Natalie M. Rosinsky
Publisher: Capstone
ISBN: 0756543150
Category : Drugs
Languages : en
Pages : 34

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Book Description
Discusses the history of pharmaceuticals, and how vaccines, antibiotics, and pain relievers are just a few of the discoveries that changed our world by helping us live longer, healthier lives.

The Click Moment

The Click Moment PDF Author: Frans Johansson
Publisher: Penguin UK
ISBN: 0241963516
Category : Business & Economics
Languages : en
Pages : 243

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Book Description
In The Click Moment, Frans Johansson, author of The Medici Effect, shows how to stay ahead when you can't predict the future Success is random. But we can capture this randomness and turn it in our favour. According to bestselling author Frans Johansson, planning and careful analysis no longer guarantee success. But dig deep into the actions of successful people and organizations and you find one common theme. A turning point occurs and they take advantage of that 'click moment' to change their fate. Diane von Furstenberg saw a matching skirt and top on TV and the wrap-dress was born. Microsoft Windows was on the brink of being shut down until two people met at a party. Starbucks sold brewing equipment until Howard Schultz experienced his first latte. These people capitalized on their luck and altered the course of their lives. The Click Moment shows how we can follow them by opening ourselves up to chance encounters and harnessing the forces of success that follow.