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Author: Peter Benner
Publisher: Springer
ISBN: 3319084372
Category : Mathematics
Languages : en
Pages : 401
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Book Description
This edited volume provides insights into and tools for the modeling, analysis, optimization, and control of large-scale networks in the life sciences and in engineering. Large-scale systems are often the result of networked interactions between a large number of subsystems, and their analysis and control are becoming increasingly important. The chapters of this book present the basic concepts and theoretical foundations of network theory and discuss its applications in different scientific areas such as biochemical reactions, chemical production processes, systems biology, electrical circuits, and mobile agents. The aim is to identify common concepts, to understand the underlying mathematical ideas, and to inspire discussions across the borders of the various disciplines. The book originates from the interdisciplinary summer school “Large Scale Networks in Engineering and Life Sciences” hosted by the International Max Planck Research School Magdeburg, September 26-30, 2011, and will therefore be of interest to mathematicians, engineers, physicists, biologists, chemists, and anyone involved in the network sciences. In particular, due to their introductory nature the chapters can serve individually or as a whole as the basis of graduate courses and seminars, future summer schools, or as reference material for practitioners in the network sciences.
Author: Peter Benner
Publisher: Springer
ISBN: 3319084372
Category : Mathematics
Languages : en
Pages : 401
Get Book Here
Book Description
This edited volume provides insights into and tools for the modeling, analysis, optimization, and control of large-scale networks in the life sciences and in engineering. Large-scale systems are often the result of networked interactions between a large number of subsystems, and their analysis and control are becoming increasingly important. The chapters of this book present the basic concepts and theoretical foundations of network theory and discuss its applications in different scientific areas such as biochemical reactions, chemical production processes, systems biology, electrical circuits, and mobile agents. The aim is to identify common concepts, to understand the underlying mathematical ideas, and to inspire discussions across the borders of the various disciplines. The book originates from the interdisciplinary summer school “Large Scale Networks in Engineering and Life Sciences” hosted by the International Max Planck Research School Magdeburg, September 26-30, 2011, and will therefore be of interest to mathematicians, engineers, physicists, biologists, chemists, and anyone involved in the network sciences. In particular, due to their introductory nature the chapters can serve individually or as a whole as the basis of graduate courses and seminars, future summer schools, or as reference material for practitioners in the network sciences.
Author: Alessandro Vespignani
Publisher: World Scientific
ISBN: 9814475416
Category : Computers
Languages : en
Pages : 264
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Book Description
This book is the culmination of three years of research effort on a multidisciplinary project in which physicists, mathematicians, computer scientists and social scientists worked together to arrive at a unifying picture of complex networks. The contributed chapters form a reference for the various problems in data analysis visualization and modeling of complex networks.
Author: Matthias Voigt
Publisher: Logos Verlag Berlin GmbH
ISBN: 3832541187
Category : Mathematics
Languages : en
Pages : 314
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Book Description
This thesis considers the linear-quadratic optimal control problem for differential-algebraic systems. In this first part, a complete theoretical analysis of this problem is presented. The basis is a new differential-algebraic version of the Kalman-Yakubovich-Popov (KYP) lemma. One focus is the analysis of the solution structure of the associated descriptor KYP inequality. In particular, rank-minimizing, stabilizing, and extremal solutions are characterized which gives a deep insight into the structure of the problem. Further contributions include new relations of the descriptor KYP inequality to structured matrix pencils, conditions for the existence of nonpositive solutions, and the application of the new theory to the characterization of dissipative systems and the factorization of rational matrix-valued functions. The second part of this thesis focuses on robustness questions, i.e., the influence of perturbations on system properties like dissipativity and stability is discussed. Characterizations for the distance of a dissipative systems to the set of non-dissipative systems are given which lead to a numerical method for computing this distance. Furthermore, the problem of computing the H-infinity-norm of a large-scale differential-algebraic system is considered. Two approaches for this computation are introduced and compared to each other.
Author: Marco Pellegrini
Publisher: Frontiers Media SA
ISBN: 2832532039
Category : Science
Languages : en
Pages : 168
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Book Description
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309089123
Category : Medical
Languages : en
Pages : 297
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Book Description
The nature of biomedical research has been evolving in recent years. Technological advances that make it easier to study the vast complexity of biological systems have led to the initiation of projects with a larger scale and scope. In many cases, these large-scale analyses may be the most efficient and effective way to extract functional information from complex biological systems. Large-Scale Biomedical Science: Exploring Strategies for Research looks at the role of these new large-scale projects in the biomedical sciences. Though written by the National Academies' Cancer Policy Board, this book addresses implications of large-scale science extending far beyond cancer research. It also identifies obstacles to the implementation of these projects, and makes recommendations to improve the process. The ultimate goal of biomedical research is to advance knowledge and provide useful innovations to society. Determining the best and most efficient method for accomplishing that goal, however, is a continuing and evolving challenge. The recommendations presented in Large-Scale Biomedical Science are intended to facilitate a more open, inclusive, and accountable approach to large-scale biomedical research, which in turn will maximize progress in understanding and controlling human disease.
Author: Ming Chen
Publisher: Springer Science & Business Media
ISBN: 3642412815
Category : Computers
Languages : en
Pages : 385
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Book Description
Approaches in Integrative Bioinformatics provides a basic introduction to biological information systems, as well as guidance for the computational analysis of systems biology. This book also covers a range of issues and methods that reveal the multitude of omics data integration types and the relevance that integrative bioinformatics has today. Topics include biological data integration and manipulation, modeling and simulation of metabolic networks, transcriptomics and phenomics, and virtual cell approaches, as well as a number of applications of network biology. It helps to illustrate the value of integrative bioinformatics approaches to the life sciences. This book is intended for researchers and graduate students in the field of Bioinformatics. Professor Ming Chen is the Director of the Bioinformatics Laboratory at the College of Life Sciences, Zhejiang University, Hangzhou, China. Professor Ralf Hofestädt is the Chair of the Department of Bioinformatics and Medical Informatics, Bielefeld University, Germany.
Author: John Fitzgerald
Publisher: Springer
ISBN: 3319489895
Category : Computers
Languages : en
Pages : 807
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Book Description
This book constitutes the refereed proceedings of the 21st International Symposium on Formal Methods, FM 2016, held in Limassol, Cyprus, in November 2016. The 38 full papers and 11 short papers presented together with one abstract of an invited talk and one invited presentation were carefully reviewed and selected from 162 submissions. The broad topics of interest for FM include: interdisciplinary formal methods; formal methods in practice; tools for formal methods; role of formal methods in software and systems engineering; theoretical foundations.
Author: Paul Janmey
Publisher: Springer
ISBN: 3319179306
Category : Science
Languages : en
Pages : 435
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Book Description
This book presents an Assessment of Physical Sciences and Engineering Advances in Life Sciences and Oncology (APHELION) by a panel of experts. It covers the status and trends of applying physical sciences and engineering principles to oncology research in leading laboratories and organizations in Europe and Asia. The book elaborates on the six topics identified by the panel that have the greatest potential to advance understanding and treatment of cancer, each covered by a chapter in the book. The study was sponsored by the National Cancer Institute (NCI) at the National Institute of Health (NIH), the National Science Foundation (NSF) and the National Institute of Biomedical Imaging and Bioengineering at the NIH in the US under a cooperative agreement with the World Technology Evaluation Center (WTEC).
Author: Marcelo S. Reis
Publisher: Springer Nature
ISBN: 3031427157
Category : Science
Languages : en
Pages : 174
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Book Description
This book constitutes the proceedings of the 16th Brazilian Symposium on Bioinformatics on Advances in Bioinformatics and Computational Biology, BSB 2023, which took place in Curitiba, Brazil, in June 2023. The 11 full papers and 3 short papers presented in this volume were carefully reviewed and selected from 24 submissions. The papers focus on bioinformatics, computational biology, Biological Databases, Biological Networks, Cheminformatics, Evolutionary Genomics, Computational Proteomics, Systems Biology, Drug Design, Genomics, Machine Learning applications in Bioinformatics, Metagenomics, Molecular Docking and Modeling, Molecular Evolution and Phylogenetics, Protein Structure and Modeling, Proteomics, Transcriptomics, Single-Cell Analysis, Workflows in Bioinformatics.
Author: John N. Parker
Publisher: Routledge
ISBN: 1317164466
Category : Social Science
Languages : en
Pages : 301
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Book Description
In recent years the organisation and practice of collaboration in the life sciences has undergone radical transformations, owing to the advent of big science enterprises, newly developed data gathering and storage technologies, increasing levels of interdisciplinarity, and changing societal expectations for science. Collaboration in the New Life Sciences examines the causes and consequences of changing patterns of scientific collaboration in the life sciences. This book presents an understanding of how and why collaboration in the life sciences is changing and the effects of these changes on scientific knowledge, the work lives and experiences of scientists, social policy and society. Through a series of thematically arranged chapters, it considers the social, technical, and organizational facets of collaboration, addressing not only the rise of new forms of collaboration in the life sciences, but also examining recent developments in two broad research areas: ecology and environment, and the molecular life sciences. With an international team of experts presenting case studies and analyses drawn from the US, UK, Asia and Europe, Collaboration in the New Life Sciences will appeal not only to scholars and students of science and technology studies, but also to those interested in science and social policy, and the sociology of work and organisations.
