Large Scale Methods to Enumerate Extreme Rays and Elementary Modes (color Print) PDF Download
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Author: Marco Terzer
Publisher: Lulu.com
ISBN: 1445248794
Category :
Languages : en
Pages : 170
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Book Description
A major challenge in systems biology is to improve the understanding of complex metabolic networks. Here, we focus on structural analysis since it requires mainly reaction stoichiometries, in contrary to detailed dynamic methods that are often limited by insufficient knowledge on mechanisms and parameters. Thermodynamic reaction constraints and the steady state assumption reduce the solution space for valid reaction fluxes to a convex polyhedral cone. Pathway analysis methods aim at finding a unique generating set for the flux cone---called extreme rays or elementary modes. We describe critical aspects for an efficient implementation of the double description method for large scale application. The efficiency of introduced techniques is demonstrated with large application examples from combinatorics and systems biology.
Author: Marco Terzer
Publisher: Lulu.com
ISBN: 1445248794
Category :
Languages : en
Pages : 170
Get Book Here
Book Description
A major challenge in systems biology is to improve the understanding of complex metabolic networks. Here, we focus on structural analysis since it requires mainly reaction stoichiometries, in contrary to detailed dynamic methods that are often limited by insufficient knowledge on mechanisms and parameters. Thermodynamic reaction constraints and the steady state assumption reduce the solution space for valid reaction fluxes to a convex polyhedral cone. Pathway analysis methods aim at finding a unique generating set for the flux cone---called extreme rays or elementary modes. We describe critical aspects for an efficient implementation of the double description method for large scale application. The efficiency of introduced techniques is demonstrated with large application examples from combinatorics and systems biology.
Author: American Public Health Association
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 1254
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Book Description
Author: Alexander Altland
Publisher: Cambridge University Press
ISBN: 0521769752
Category : Science
Languages : en
Pages : 785
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Book Description
This primer is aimed at elevating graduate students of condensed matter theory to a level where they can engage in independent research. Topics covered include second quantisation, path and functional field integration, mean-field theory and collective phenomena.
Author: Laura F. Salazar
Publisher: John Wiley & Sons
ISBN: 111840906X
Category : Medical
Languages : en
Pages : 610
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Book Description
The bestselling textbook to understanding health research, updated and expanded Research Methods in Health Promotion provides students and practitioners with essential knowledge and skills regarding the design, implementation, analysis, and interpretation of research in the field of health promotion. Now in its second edition, this bestselling textbook has been updated with more recent research methodologies and additional information on sampling, participatory and survey research, and qualitative data analysis. The entire research process is covered, with specific points relating to both qualitative and quantitative research. By breaking the daunting process of research into simple and well-defined steps, this user-friendly text encourages students to think about research as a sequential process and provides explanations that facilitate better understanding of each step in the research process. A separate set of chapters cover the more quantitative methodological areas including designs, measurement, sampling, and data analysis in depth, giving readers the understanding they need to apply in practice. This book also provides applied chapters that illustrate the practical aspects of the research process, along with other critical information including grant writing and scientific writing. Evaluate the ethics, design, analysis, and interpretation of research Identify and understand the key components of research studies Analyze and interpret the results of experimental and survey research designs Understand the process of publishing a research report and constructing a grant proposal Research Methods in Health Promotion is ideal for both undergrad and graduate methods courses in health promotion and public health.
Author: Keith D. Harries
Publisher:
ISBN:
Category : Cartography
Languages : en
Pages : 220
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Book Description
Author: Marguerite G. Lodico
Publisher: John Wiley & Sons
ISBN: 0470588691
Category : Psychology
Languages : en
Pages : 560
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Book Description
Methods in Educational Research Methods in Educational Research is designed to prepare students for the real world of educational research. It focuses on scientifically-based methods, school accountability, and the professional demands of the twenty-first century, empowering researchers to take an active role in conducting research in their classrooms, districts, and the greater educational community. Like the first edition, this edition helps students, educators, and researchers develop a broad and deep understanding of research methodologies. It includes substantial new content on the impact of No Child Left Behind legislation, school reform, quantitative and qualitative methodologies, logic modeling, action research, and other areas. Special features to assist the teaching and learning processes include vignettes illustrating research tied to practice, suggested readings at the end of each chapter, and discussion questions to reinforce chapter content. Praise for the Previous Edition "A new attempt to make this subject more relevant and appealing to students. Most striking is how useful this book is because it is really grounded in educational research. It is very well written and quite relevant for educational researchers or for the student hoping to become one." -PsycCRITIQUES/American Psychological Association "I applaud the authors for their attempt to cover a wide range of material. The straightforward language of the book helps make the material understandable for readers." -Journal of MultiDisciplinary Evaluation
Author: Wiebe E. Bijker
Publisher: MIT Press
ISBN: 9780262521376
Category : Science
Languages : en
Pages : 428
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Book Description
"The impact of technology on society is clear and unmistakeable. The influence of society on technology is more subtle. The 13 essays in this book have been written by a diverse group of scholars united by a common interest in creating a new field - the sociology of technology. They draw on a wide array of case studies - from cooking stoves to missile systems, from 15th-century Portugal to today's Al labs - to outline an original research program based on a synthesis of ideas from the social studies of science and the history of technology. Together they affirm the need for a study of technology that gives equal weight to technical, social, economic, and political questions"--Back cover.
Author: American Society of Heating, Refrigerating and Air-Conditioning Engineers
Publisher:
ISBN: 9781939200426
Category : Air conditioning
Languages : en
Pages : 0
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Book Description
Moisture control is fundamental to the proper functioning of any building. Controlling moisture is important to protect occupants from adverse health effects and to protect the building, its mechanical systems and its contents from physical or chemical damage. Yet, moisture problems are so common in buildings, many people consider them inevitable. Excessive moisture accumulation plagues buildings throughout the United States, from tropical Hawaii to arctic Alaska and from the hot, humid Gulf Coast to the hot, dry Sonoran Desert. Between 1994 and 1998, the U.S. Environmental Protection Agency (EPA) Building Assessment Survey and Evaluation (BASE) study collected information about the indoor air quality of 100 randomly selected public and private office buildings in the 10 U.S. climatic regions.
Author: Peter YU
Publisher: Springer Science & Business Media
ISBN: 3540264752
Category : Technology & Engineering
Languages : en
Pages : 651
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Book Description
Excellent bridge between general solid-state physics textbook and research articles packed with providing detailed explanations of the electronic, vibrational, transport, and optical properties of semiconductors "The most striking feature of the book is its modern outlook ... provides a wonderful foundation. The most wonderful feature is its efficient style of exposition ... an excellent book." Physics Today "Presents the theoretical derivations carefully and in detail and gives thorough discussions of the experimental results it presents. This makes it an excellent textbook both for learners and for more experienced researchers wishing to check facts. I have enjoyed reading it and strongly recommend it as a text for anyone working with semiconductors ... I know of no better text ... I am sure most semiconductor physicists will find this book useful and I recommend it to them." Contemporary Physics Offers much new material: an extensive appendix about the important and by now well-established, deep center known as the DX center, additional problems and the solutions to over fifty of the problems at the end of the various chapters.
Author: K. Gerald van den Boogaart
Publisher: Springer Science & Business Media
ISBN: 3642368093
Category : Mathematics
Languages : en
Pages : 269
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Book Description
This book presents the statistical analysis of compositional data sets, i.e., data in percentages, proportions, concentrations, etc. The subject is covered from its grounding principles to the practical use in descriptive exploratory analysis, robust linear models and advanced multivariate statistical methods, including zeros and missing values, and paying special attention to data visualization and model display issues. Many illustrated examples and code chunks guide the reader into their modeling and interpretation. And, though the book primarily serves as a reference guide for the R package “compositions,” it is also a general introductory text on Compositional Data Analysis. Awareness of their special characteristics spread in the Geosciences in the early sixties, but a strategy for properly dealing with them was not available until the works of Aitchison in the eighties. Since then, research has expanded our understanding of their theoretical principles and the potentials and limitations of their interpretation. This is the first comprehensive textbook addressing these issues, as well as their practical implications with regard to software. The book is intended for scientists interested in statistically analyzing their compositional data. The subject enjoys relatively broad awareness in the geosciences and environmental sciences, but the spectrum of recent applications also covers areas like medicine, official statistics, and economics. Readers should be familiar with basic univariate and multivariate statistics. Knowledge of R is recommended but not required, as the book is self-contained.
