Landmark Papers in Internal Medicine

Landmark Papers in Internal Medicine PDF Author: Harold C. Sox
Publisher: ACP Press
ISBN: 9781934465073
Category : Internal medicine
Languages : en
Pages : 550

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Book Description
ACPs journal, Annals of Internal Medicine, is one of the most prestigious journals in medicine. This new book looks at the landmark papers published in Annals, as selected by leading experts from each subspecialty of internal medicine, and how they impacted (and continue to influence) medical science.

Landmark Papers in Internal Medicine

Landmark Papers in Internal Medicine PDF Author: Harold C. Sox
Publisher: ACP Press
ISBN: 9781934465073
Category : Internal medicine
Languages : en
Pages : 550

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Book Description
ACPs journal, Annals of Internal Medicine, is one of the most prestigious journals in medicine. This new book looks at the landmark papers published in Annals, as selected by leading experts from each subspecialty of internal medicine, and how they impacted (and continue to influence) medical science.

Landmark Papers in General Surgery

Landmark Papers in General Surgery PDF Author: Graham MacKay
Publisher: OUP Oxford
ISBN: 0191654272
Category : Medical
Languages : en
Pages : 416

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Book Description
Landmark Papers in General Surgery will give surgeons, surgical trainees and other healthcare professionals an expert appraisal of key papers, and fast access to the evidence base behind current clinical practice in General Surgery. Each chapter draws together a fascinating selection of the most important clinical trials across every subspecialty within General Surgery, as selected and appraised by a panel of experts. Organized according to a common format, each discussion offers a clear structure by which to appraise the medical literature. Following a background summary of each trial, experts discuss the impact of the research and critique the methods used, giving the reader rapid understanding of the paper's place within the wider field of research. This emphasis on the tools of critical appraisal is enhanced by an introductory chapter equipping the reader with the skills required to knowledgeably appraise a research paper. For clinicians needing to keep abreast of the vast scope of medical research, this book will prove an interesting and timesaving resource, but it will also appeal to allied health professionals keen to improve the depth of their understanding of surgery. By bringing together the evidence base with expert guidance on critical appraisal, higher surgical trainees preparing for the academic and specialty sections of the FRCS exit examination will also find the text invaluable as a means of consolidating and nuancing their knowledge.

50 Studies Every Internist Should Know

50 Studies Every Internist Should Know PDF Author: Kristopher J. Swiger
Publisher: Oxford University Press
ISBN: 0199349959
Category : Medical
Languages : en
Pages : 353

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Book Description
50 Studies Every Internist Should Know presents key studies that shape today's practice of internal medicine. Selected using a rigorous methodology, the studies cover topics including: preventative medicine, endocrinology, hematology and oncology, musculoskeletal diseases, nephrology, gastroenterology, infectious diseases, cardiology, pulmonology, geriatrics and palliative care, and mental health. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice.

50 Landmark Papers every Intensivist Should Know

50 Landmark Papers every Intensivist Should Know PDF Author: Stephen M. Cohn
Publisher: CRC Press
ISBN: 1000432475
Category : Medical
Languages : en
Pages : 339

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Book Description
This book identifies the key scientific articles in the field of Intensive Care and explains why these papers are important in contemporary clinical management. Identifying those influential contributors who have shaped the practice of modern Intensive care practice, the book includes commentaries on 50 seminal papers in a wide range of areas. enal This an invaluable reference for trainees, fellows, and surgeons studying for exams, as well as for seasoned surgeons and physicians who want to stay current in their field.

Landmark Trials in Oncology

Landmark Trials in Oncology PDF Author: Santosh Yajnik
Publisher: Springer
ISBN: 3030144054
Category : Medical
Languages : en
Pages : 325

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Book Description
This book describes the evolution of treatment in oncology through the lens of approximately 250 landmark clinical trials. The well-designed clinical trial is essential to the practice of medicine. There is no field that has embraced or been transformed more by the clinical trial than oncology. Each primary cancer site has a remarkable story that can be told through clinical trials. For example, patients who presented decades ago with soft tissue sarcoma of the extremities would invariably undergo limb amputation. The landmark National Cancer Institute study by Rosenberg et al. randomized patients to limb sparing surgery followed by adjuvant radiation therapy compared with limb amputation. This study helped change the standard of care by allowing most patients to retain their functioning limbs with an improvement in quality of life and no compromise in overall survival. Such major clinical trials for common malignancies including breast, prostate, lung, gastrointestinal, genitourinary, and gynecologic cancers are discussed. Because oncology is multidisciplinary, this book should be of interest for radiation oncologists, surgeons, medical oncologists, and other physicians interested in learning more about the landmark trials that have shaped oncology.

Landmark Papers in Cardiovascular Medicine

Landmark Papers in Cardiovascular Medicine PDF Author: Tony Gershlick
Publisher: Oxford University Press
ISBN: 0199594767
Category : Medical
Languages : en
Pages : 520

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Book Description
Landmark Papers in Cardiovascular Medicine provides a thorough and wide-ranging analysis of core examples of novel research, clinical trials and seminal papers that have paved the way for breakthroughs in the management of the entire spectrum of cardiovascular disease.

2 Minute Medicine's the Classics in Medicine

2 Minute Medicine's the Classics in Medicine PDF Author: Marc Succi
Publisher:
ISBN: 9780996304238
Category :
Languages : en
Pages : 0

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Book Description


Small Clinical Trials

Small Clinical Trials PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309171148
Category : Medical
Languages : en
Pages : 221

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Book Description
Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

50 Landmark Papers Every Acute Care Surgeon Should Know

50 Landmark Papers Every Acute Care Surgeon Should Know PDF Author: Stephen M Cohn
Publisher: CRC Press
ISBN: 1000084817
Category : Medical
Languages : en
Pages : 483

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Book Description
In 50 Landmark Papers every Acute Care Surgeon Should Know, editors Stephen Cohn and Peter Rhee have compiled a selection of the most influential recent contributions to the specialty of acute care surgery/emergency surgery. This book comprises 50 thought-provoking and relevant topics, reviewing carefully selected papers to update the readers on what has been published in the last decade. 50 key papers cover the most relevant studies from a wide range of topics from Acute Cholecystitis to Ventilator-Associated Pneumonia. This book is of interest to surgical residents and trainees, Trauma and Surgical Critical Care fellows and all members of the Acute Care team. This is both an informative and personal look at evidence-based topics, and is relevant to all general and acute care surgeons. About the Editors Stephen M. Cohn, MD FACS Hackensack Meridian School of Medicine at Seton Hall University Nutley, New Jersey, USA Peter Rhee New York Medical College Westchester Medical Center Valhalla, New York, USA

50 Landmark Papers Every Trauma Surgeon Should Know

50 Landmark Papers Every Trauma Surgeon Should Know PDF Author: Stephen M. Cohn
Publisher:
ISBN: 9781138506299
Category : Traumatology
Languages : en
Pages : 0

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Book Description
In 50 Landmark papers authors Stephen Cohn and Ara Feinstein have compiled a selection of the most influential contributions to the specialty of trauma surgery.This book comprises 50 thought provoking reviews of each carefully selected paper, and explains how trauma surgery practice changed as a result of this research .