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Author: K. E. Herold
Publisher: Caister Academic Press Limited
ISBN: 9781904455479
Category : Science
Languages : en
Pages : 0
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Book Description
Lab-on-a-Chip (LOC) technology is a rapidly expanding area of science. It has applications in biotechnology, medicine, clinical diagnostics, chemical engineering, and pharmaceutics. As the lab-on-a-chip systems increase in importance and complexity it is important for scientists to become familiar not only with the technology but also with the potential applications. The editors of this book have brought together expert authors from many countries to produce a comprehensive volume focusing on the applications of LOC technology in the biomedical and life sciences. The first section includes chapters on LOC biomolecule separation. Separation of biomolecules is an important element of various clinical laboratories and is required for many down stream analytical applications. Various electrophoresis and liquid chromatography applications for proteins and DNA are described as well as methods for cell separation, with an emphasis on blood cell separation, which have many important clinical applications. The second part includes chapters on analysis and manipulation technologies. Authors describe protein, genetic (mainly PCR) and transcriptome analysis with examples from research and clinical applications, as well as cell manipulation and analysis including cell viability analysis and microorganism capturing. A skillful selection of topics of exceptional importance to current science ensures that this book will be of major value to a wide range of molecular biologists, clinical scientists, microbiologists, biochemists and anyone interested in LOC technology or developing applications for LOC devices.
Author: K. E. Herold
Publisher: Caister Academic Press Limited
ISBN: 9781904455479
Category : Science
Languages : en
Pages : 0
Get Book Here
Book Description
Lab-on-a-Chip (LOC) technology is a rapidly expanding area of science. It has applications in biotechnology, medicine, clinical diagnostics, chemical engineering, and pharmaceutics. As the lab-on-a-chip systems increase in importance and complexity it is important for scientists to become familiar not only with the technology but also with the potential applications. The editors of this book have brought together expert authors from many countries to produce a comprehensive volume focusing on the applications of LOC technology in the biomedical and life sciences. The first section includes chapters on LOC biomolecule separation. Separation of biomolecules is an important element of various clinical laboratories and is required for many down stream analytical applications. Various electrophoresis and liquid chromatography applications for proteins and DNA are described as well as methods for cell separation, with an emphasis on blood cell separation, which have many important clinical applications. The second part includes chapters on analysis and manipulation technologies. Authors describe protein, genetic (mainly PCR) and transcriptome analysis with examples from research and clinical applications, as well as cell manipulation and analysis including cell viability analysis and microorganism capturing. A skillful selection of topics of exceptional importance to current science ensures that this book will be of major value to a wide range of molecular biologists, clinical scientists, microbiologists, biochemists and anyone interested in LOC technology or developing applications for LOC devices.
Author: Keith E. Herold
Publisher:
ISBN: 9781912530939
Category :
Languages : en
Pages : 316
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Book Description
The editors of this book have brought together expert authors from many countries to produce a comprehensive volume focusing on the applications of LOC technology in the biomedical and life sciences. The first section includes chapters on LOC biomolecule separation. Separation of biomolecules is an important element of various clinical laboratories and is required for many down stream analytical applications. Various electrophoresis and liquid chromatography applications for proteins and DNA are described as well as methods for cell separation, with an emphasis on blood cell separation, which.
Author: Paul C.H. Li
Publisher: CRC Press
ISBN: 142002745X
Category : Medical
Languages : en
Pages : 529
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Book Description
The microfluidic lab-on-a-chip allows scientists to conduct chemical and biochemical analysis in a miniaturized format so small that properties and effects are successfully enhanced, and processes seamlessly integrated. This microscale advantage translates into greater sensitivity, more accurate results, and better information. Microfluidic
Author: Fouad Sabry
Publisher: One Billion Knowledgeable
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 367
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Book Description
What Is Lab on a Chip A lab-on-a-chip (LOC) is a device that integrates one or several laboratory functions on a single integrated circuit of only millimeters to a few square centimeters to achieve automation and high-throughput screening. LOCs can handle extremely small fluid volumes down to less than pico-liters. Lab-on-a-chip devices are a subset of microelectromechanical systems (MEMS) devices and sometimes called "micro total analysis systems" (mTAS). LOCs may use microfluidics, the physics, manipulation and study of minute amounts of fluids. However, strictly regarded "lab-on-a-chip" indicates generally the scaling of single or multiple lab processes down to chip-format, whereas "mTAS" is dedicated to the integration of the total sequence of lab processes to perform chemical analysis. The term "lab-on-a-chip" was introduced when it turned out that mTAS technologies were applicable for more than only analysis purposes. How You Will Benefit (I) Insights, and validations about the following topics: Chapter 1: Lab-on-a-chip Chapter 2: Assay Chapter 3: Dielectrophoresis Chapter 4: Immunoassay Chapter 5: Electrophysiology Chapter 6: Microfluidics Chapter 7: Materials science (II) Answering the public top questions about lab on a chip. (III) Real world examples for the usage of lab on a chip in many fields. (IV) 17 appendices to explain, briefly, 266 emerging technologies in each industry to have 360-degree full understanding of lab on a chip' technologies. Who This Book Is For Professionals, undergraduate and graduate students, enthusiasts, hobbyists, and those who want to go beyond basic knowledge or information for any kind of lab on a chip.
Author: Dimitrios P. Nikolelis
Publisher: CRC Press
ISBN: 1466576324
Category : Science
Languages : en
Pages : 832
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Book Description
Biosensors are poised to make a large impact in environmental, food, and biomedical applications, as they clearly offer advantages over standard analytical methods, including minimal sample preparation and handling, real-time detection, rapid detection of analytes, and the ability to be used by non-skilled personnel. Covering numerous applications of biosensors used in food and the environment, Portable Biosensing of Food Toxicants and Environmental Pollutants presents basic knowledge on biosensor technology at a postgraduate level and explores the latest advances in chemical sensor technology for researchers. By providing useful, state-of-the-art information on recent developments in biosensing devices, the book offers both newcomers and experts a roadmap to this technology. In the book, distinguished researchers from around the world show how portable and handheld nanosensors, such as dynamic DNA and protein arrays, enable rapid and accurate detection of environmental pollutants and pathogens. The book first introduces the basic principles of biosensing for newcomers to the technology. It then explains how the integration of a "receptor" can provide analytically useful information. It also describes trends in biosensing and examines how a small-sized device can have portability for the in situ determination of toxicants. The book concludes with several examples illustrating how to determine toxicants in food and environmental samples.
Author: John G. Webster
Publisher: CRC Press
ISBN: 1439808473
Category : Medical
Languages : en
Pages : 620
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Book Description
The Physiological Measurement Handbook presents an extensive range of topics that encompass the subject of measurement in all departments of medicine. The handbook describes the use of instruments and techniques for practical measurements required in medicine. It covers sensors, techniques, hardware, and software as well as information on processing systems, automatic data acquisition, reduction and analysis, and their incorporation for diagnosis. Suitable for both instrumentation designers and users, the handbook enables biomedical engineers, scientists, researchers, students, health care personnel, and those in the medical device industry to explore the different methods available for measuring a particular physiological variable. It helps readers select the most suitable method by comparing alternative methods and their advantages and disadvantages. In addition, the book provides equations for readers focused on discovering applications and solving diagnostic problems arising in medical fields not necessarily in their specialty. It also includes specialized information needed by readers who want to learn advanced applications of the subject, evaluative opinions, and possible areas for future study.
Author: Management Association, Information Resources
Publisher: IGI Global
ISBN: 1609605624
Category : Medical
Languages : en
Pages : 2366
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Book Description
"This multi-volume book delves into the many applications of information technology ranging from digitizing patient records to high-performance computing, to medical imaging and diagnostic technologies, and much more"--
Author: Mohamed Ibrahim
Publisher: CRC Press
ISBN: 1000082660
Category : Technology & Engineering
Languages : en
Pages : 349
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Book Description
A microfluidic biochip is an engineered fluidic device that controls the flow of analytes, thereby enabling a variety of useful applications. According to recent studies, the fields that are best set to benefit from the microfluidics technology, also known as lab-on-chip technology, include forensic identification, clinical chemistry, point-of-care (PoC) diagnostics, and drug discovery. The growth in such fields has significantly amplified the impact of microfluidics technology, whose market value is forecast to grow from $4 billion in 2017 to $13.2 billion by 2023. The rapid evolution of lab-on-chip technologies opens up opportunities for new biological or chemical science areas that can be directly facilitated by sensor-based microfluidics control. For example, the digital microfluidics-based ePlex system from GenMarkDx enables automated disease diagnosis and can bring syndromic testing near patients everywhere. However, as the applications of molecular biology grow, the adoption of microfluidics in many applications has not grown at the same pace, despite the concerted effort of microfluidic systems engineers. Recent studies suggest that state-of-the-art design techniques for microfluidics have two major drawbacks that need to be addressed appropriately: (1) current lab-on-chip systems were only optimized as auxiliary components and are only suitable for sample-limited analyses; therefore, their capabilities may not cope with the requirements of contemporary molecular biology applications; (2) the integrity of these automated lab-on-chip systems and their biochemical operations are still an open question since no protection schemes were developed against adversarial contamination or result-manipulation attacks. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms provides solutions to these challenges by introducing a new design flow based on the realistic modeling of contemporary molecular biology protocols. It also presents a microfluidic security flow that provides a high-level of confidence in the integrity of such protocols. In summary, this book creates a new research field as it bridges the technical skills gap between microfluidic systems and molecular biology protocols but it is viewed from the perspective of an electronic/systems engineer.
Author: Fouad Sabry
Publisher: One Billion Knowledgeable
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 477
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Book Description
What Is Microfluidics Microfluidics refers to the behavior, precise control, and manipulation of fluids that are geometrically constrained to a small scale at which surface forces dominate volumetric forces. It is a multidisciplinary field that involves engineering, physics, chemistry, biochemistry, nanotechnology, and biotechnology. It has practical applications in the design of systems that process low volumes of fluids to achieve multiplexing, automation, and high-throughput screening. Microfluidics emerged in the beginning of the 1980s and is used in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. How You Will Benefit (I) Insights, and validations about the following topics: Chapter 1: Microfluidics Chapter 2: Droplet-based microfluidics Chapter 3: Digital microfluidics Chapter 4: Paper-based microfluidics Chapter 5: Microfluidic cell culture Chapter 6: Electroosmotic pump Chapter 7: Materials science (II) Answering the public top questions about microfluidics. (III) Real world examples for the usage of microfluidics in many fields. (IV) 17 appendices to explain, briefly, 266 emerging technologies in each industry to have 360-degree full understanding of microfluidics' technologies. Who This Book Is For Professionals, undergraduate and graduate students, enthusiasts, hobbyists, and those who want to go beyond basic knowledge or information for any kind of microfluidics.
Author: Vijai Singh
Publisher: Academic Press
ISBN: 0323859860
Category : Science
Languages : en
Pages : 487
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Book Description
New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas. - Offers basic understanding and knowledge in several aspects of synthetic biology - Covers state-of-the-art tools and technologies of synthetic biology, including promoter design, DNA synthesis, DNA sequencing, genome design, directed evolution, protein engineering, computational tools, phage design, CRISPR-Cas systems, and more - Discusses the applications of synthetic biology for smart drugs, vaccines, therapeutics, drug discovery, self-assembled materials, cell free systems, microfluidics, and more
