Enzyme Mechanism from Isotope Effects

Enzyme Mechanism from Isotope Effects PDF Author: Paul F. Cook
Publisher: CRC Press
ISBN: 9780849353123
Category : Medical
Languages : en
Pages : 656

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Book Description
Isotope effects have become one of the most powerful tools available to the enzymologist for probing enzymic mechanisms. Enzyme Mechanism from Isotope Effects presents the basic theory underlying isotope effects, including the latest findings on proton tunneling and coupled atomic notions. Specific theoretical applications are emphasized in regard to the types of information that can be obtained using isotope effects. The book also examines recent theoretical treatments of the product dependence of deuterium isotope effects, multiple isotope effects and isotope effects on intermediate partitioning. Other topics include a complete discussion of methods for measuring isotope effects, including a detailed description of the use of the isotope ratio mass spectrometer to obtain isotope effects, and a review of the literature regarding mechanistic information obtained from isotope effects for individual classes of enzyme-catalyzed reactions. Enzyme Mechanism from Isotope Effects is an excellent reference source for investigators using isotope effects in their research. The book is also valuable for reference libraries and instructors teaching courses in enzyme mechanism.

Enzyme Mechanism from Isotope Effects

Enzyme Mechanism from Isotope Effects PDF Author: Paul F. Cook
Publisher: CRC Press
ISBN: 9780849353123
Category : Medical
Languages : en
Pages : 656

Get Book Here

Book Description
Isotope effects have become one of the most powerful tools available to the enzymologist for probing enzymic mechanisms. Enzyme Mechanism from Isotope Effects presents the basic theory underlying isotope effects, including the latest findings on proton tunneling and coupled atomic notions. Specific theoretical applications are emphasized in regard to the types of information that can be obtained using isotope effects. The book also examines recent theoretical treatments of the product dependence of deuterium isotope effects, multiple isotope effects and isotope effects on intermediate partitioning. Other topics include a complete discussion of methods for measuring isotope effects, including a detailed description of the use of the isotope ratio mass spectrometer to obtain isotope effects, and a review of the literature regarding mechanistic information obtained from isotope effects for individual classes of enzyme-catalyzed reactions. Enzyme Mechanism from Isotope Effects is an excellent reference source for investigators using isotope effects in their research. The book is also valuable for reference libraries and instructors teaching courses in enzyme mechanism.

Isotope Effects In Chemistry and Biology

Isotope Effects In Chemistry and Biology PDF Author: Amnon Kohen
Publisher: CRC Press
ISBN: 1420028022
Category : Medical
Languages : en
Pages : 1092

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Book Description
The field of isotope effects has expanded exponentially in the last decade, and researchers are finding isotopes increasingly useful in their studies. Bringing literature on the subject up to date, Isotope Effects in Chemistry and Biology covers current principles, methods, and a broad range of applications of isotope effects in the physical, biolo

Advances in Enzymology and Related Areas of Molecular Biology

Advances in Enzymology and Related Areas of Molecular Biology PDF Author: Alton Meister
Publisher: John Wiley & Sons
ISBN: 0470123834
Category : Science
Languages : en
Pages : 494

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Book Description
Advances in Enzymology and Related Areas of Molecular Biology is a seminal series in the field of biochemistry, offering researchers access to authoritative reviews of the latest discoveries in all areas of enzymology and molecular biology. These landmark volumes date back to 1941, providing an unrivaled view of the historical development of enzymology. The series offers researchers the latest understanding of enzymes, their mechanisms, reactions and evolution, roles in complex biological process, and their application in both the laboratory and industry. Each volume in the series features contributions by leading pioneers and investigators in the field from around the world. All articles are carefully edited to ensure thoroughness, quality, and readability. With its wide range of topics and long historical pedigree, Advances in Enzymology and Related Areas of Molecular Biology can be used not only by students and researchers in molecular biology, biochemistry, and enzymology, but also by any scientist interested in the discovery of an enzyme, its properties, and its applications.

Organometallics and Related Molecules for Energy Conversion

Organometallics and Related Molecules for Energy Conversion PDF Author: Wai-Yeung Wong
Publisher: Springer
ISBN: 3662460548
Category : Technology & Engineering
Languages : en
Pages : 541

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Book Description
This book presents a critical perspective of the applications of organometallic compounds (including those with metal or metalloid elements) and other related metal complexes as versatile functional materials in the transformation of light into electricity (solar energy conversion) and electricity into light (light generation in light emitting diode), in the reduction of carbon dioxide to useful chemicals, as well as in the safe and efficient production and utilization of hydrogen, which serves as an energy storage medium (i.e. energy carrier). This book focuses on recent research developments in these emerging areas, with an emphasis on fundamental concepts and current applications of functional organometallic complexes and related metal-based molecules for energy research. With contributions from front-line researchers in the field from academia and industry, this timely book provides a valuable contribution to the scientific community in the field of energy science related to metal-based molecular materials. Wai-Yeung Wong, PhD, is Chair Professor and Head of the Department of Chemistry at Hong Kong Baptist University, Hong Kong, P. R. China.

Nuclear Science Abstracts

Nuclear Science Abstracts PDF Author:
Publisher:
ISBN:
Category : Nuclear energy
Languages : en
Pages :

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Book Description


Heavy-atom Kinetic Isotope Effects

Heavy-atom Kinetic Isotope Effects PDF Author: Marvin J. Stern
Publisher:
ISBN:
Category : Chemical kinetics
Languages : en
Pages : 44

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Book Description


NBS Special Publication

NBS Special Publication PDF Author:
Publisher:
ISBN:
Category : Weights and measures
Languages : en
Pages : 44

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Book Description


Reaction Rates of Isotopic Molecules

Reaction Rates of Isotopic Molecules PDF Author: Lars C. S. Melander
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 360

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Book Description


Concerted Organic and Bio-Organic Mechanisms

Concerted Organic and Bio-Organic Mechanisms PDF Author: Andrew Williams
Publisher: CRC Press
ISBN: 1000151697
Category : Science
Languages : en
Pages : 304

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Book Description
The concept of concerted mechanisms was formulated nearly 90 years ago and virtually all general organic chemistry texts mention it. Until now, however, no monograph has addressed the concept explicitly. Over the last two decades, substantial advancements made in the development of precise methods for elucidating concerted mechanisms have heightened the need for a comprehensive text on the subject. Concerted Organic and Bio-organic Mechanisms gathers the salient materials related to this emerging field into a single text. It sets forth the precise definition of concertedness-along with working sub-definitions-and describes rigorous experimental tools chemists can use to diagnose the existence or absence of concerted mechanisms. Advances in our understanding of concerted mechanisms lead to further questions. Concerted Organic and Bio-organic Mechanisms provides the background and the tools researchers need to consider these important questions and further advance the frontiers of reactions, synthesis, and catalysis.

New Approaches for Flavin Catalysis

New Approaches for Flavin Catalysis PDF Author:
Publisher: Academic Press
ISBN: 0128168307
Category : Science
Languages : en
Pages : 566

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Book Description
New Approaches for Flavin Catalysis, Volume 620, a new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this update include Anaerobiosis and Methods for Reduction, Reduction Potentials, Anaerobic Stopped-Flow, No Glove-Box, Anaerobic Stopped-Flow, in a Glove-Box, Chemical Quenching, Oxygen Reactions, Double-mixing Stopped-Flow, Kinetic Isotope Effects and Viscosity Effects, Heavy Enzymes Synthetic Flavins & Linear Free Energy Relationships, Vibrational Spectroscopy, Stark Spectroscopy, EPR and Related Methods, Molecular Dynamics, Phylogenetic Relationships/Superfamilies, O2 and Superoxide Analogs, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Updated release includes the latest information on New Approaches for Flavin Catalysis