Kernicterus

Kernicterus PDF Author: David W. McCandless
Publisher: Springer Science & Business Media
ISBN: 1441965556
Category : Medical
Languages : en
Pages : 283

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Book Description
Kernicterus (bilirubin encephalopathy) is a highly interesting example of metabolic encephalopathy. It fills all the characteristics of a metabolic encephalopathy in that it can develop rapidly, produces signature signs and symptoms, and is amenable to successful treatment. In the absence of treatment kernicterus can produce devastating sequelae and death. The present volume will examine the biochemistry and physiology of bilirubin as well as its hepatic metabolism and renal excretion. Chapters will elaborate bodily disposition of bilirubin and its neuropathology. Both early treatments and current therapy will be discussed in detail. Phototherapy will be presented, and its efficacy and influence on incidence thoroughly examined.

Perinatal Neuropathology

Perinatal Neuropathology PDF Author: Mirna Lechpammer
Publisher:
ISBN: 9781316671863
Category : Nervous system
Languages : en
Pages :

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Book Description
"1 Clinical history, clinical correlations with placental pathology and prematurity The initial steps in the process of perinatal nervous system evaluation, namely the planning of the optimal approach and choice of samples to be obtained, are driven by the clinical context. Of key importance are the following data: a. Gestational age at time of demise (if stillborn); or gestational age and postnatal age (if liveborn), for comparison with normative standards of development (see Appendix); b. State of maternal health (age, parity, pre-existing medical conditions or ones appearing during gestation or around the time of delivery, exposure to medications/toxins/infections), and of health of siblings or other family members: - Concerns for inherited (i.e., genetic) conditions, metabolic disorders, congenital infections, etc., may indicate the need for special testing; c. Details of prenatal course, including any imaging, amniocentesis, or monitoring: - Prenatal imaging modalities most commonly consist of transabdominal ultrasonography, generally done at the time of the first prenatal visit (to confirm pregnancy) or more usually in the mid-second-trimester for detection of fetal or placental anomalies"--

Care of the Jaundiced Neonate

Care of the Jaundiced Neonate PDF Author: David K. Stevenson
Publisher: McGraw Hill Professional
ISBN: 0071766758
Category : Medical
Languages : en
Pages : 300

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Book Description
A complete, authoritative guide to the management and treatment of neonatal jaundice Care of the Jaundiced Neonate focuses exclusively on the scientific underpinnings of jaundice, as well as the care of the jaundiced neonate. Edited by three of the field’s most respected neonatal care experts, the book uniquely explains how the imbalance between bilirubin production and elimination leads to jaundice—and that hazardous levels of unconjugated bilirubin can cause kernicterus, or brain damage. In addition, you’ll find the most current and clinically relevant perspectives on the physiology, genetics, and treatment of neonatal jaundice and related hemolytic conditions. FEATURES Covers all aspects of neonatal jaundice—from the biochemistry of bilirubin production to kernicterus Begins with an in-depth examination of the complex gene-environment interactions of bilirubin-induced neurotoxicity and its role in neonatal jaundice Surveys bilirubin production and measurement, its various fractions, and the metabolism and transport of bilirubin Selected chapters highlight the physiology and epidemiology of neonatal unconjugated hyperbilirubinemia; bilirubin toxicity; prevention, screening, and postnatal management; phototherapy and other treatments; and prevention-related public policy. Concluding chapter provides an overview of the key issues surrounding the incidence of neonatal jaundice in low-middle income countries Includes informative review of risk assessment and treatment with phototherapy and other modalities provide key approaches to the effective clinical management of neonatal hyperbilirubinemia

Symptom-Based Diagnosis in Pediatrics (CHOP Morning Report)

Symptom-Based Diagnosis in Pediatrics (CHOP Morning Report) PDF Author: Samir S. Shah
Publisher: McGraw Hill Professional
ISBN: 0071601759
Category : Medical
Languages : en
Pages : 544

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Book Description
A CASE-BASED GUIDE TO PEDIATRIC DIAGNOSIS, CONVENIENTLY ORGANIZED BY PRESENTING SYMPTOMS Symptom-Based Diagnosis in Pediatrics features 19 chapters, each devoted to a common pediatric complaint. Within each chapter, five to eight case presentations teach the diagnostic approach to the symptom. The case presentations follow a consistent outline of History, Physical Examination, and Course of Illness, and are followed by discussion of the Differential Diagnosis, Diagnosis Incidence and Epidemiology, Clinical Manifestations, Diagnostic Approach, and Treatment. Cases are illustrated with vibrant full-color photographs and include numerous tables comparing potential diagnoses. Organized by symptoms--the way patients actually present More than 100 cases teach the diagnostic approach to a symptom Cases illustrate how the same complaint can have a variety of causes Full-color clinical photos and illustrations sharpen your visual diagnosis skills Valuable tables detail the most frequent causes of common symptoms CASE-BASED COVERAGE OF THE SYMPTOMS YOU'RE MOST LIKELY TO ENCOUNTER IN PEDIATRIC PRACTICE Wheezing * Decreased Activity Level * Vomiting * Coughing * Back, Joint, and Extremity Pain * Poor Weight Gain * Abdominal Pain * Altered Mental Status * Rash * Pallor * Fever * Constipation * Neck Swelling * Chest Pain * Jaundice * Abnormal Gait * Diarrhea * Syncope * Seizures Editors Samir S. Shah, MD, MSCE is Director, Division of Hospital Medicine, James M. Ewell Endowed Chair, and Attending Physician in Hospital Medicine & Infectious Diseases at Cincinnati Children’s Hospital Medical Center; and Professor in the Department of Pediatrics at the University of Cincinnati College of Medicine. Stephen Ludwig, MD is Chairman of the Graduate Medical Education Committee and Continuing Medical Education Committee and an attending physician in general pediatrics at The Children's Hospital of Philadelphia; and Emeritus Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania.

Neurosurgical Diseases

Neurosurgical Diseases PDF Author: Leon T. Lai
Publisher: Thieme
ISBN: 1638536392
Category : Medical
Languages : en
Pages : 641

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Book Description
A structured, evidence-based approach to neurosurgical decision-making for brain pathologies Evidence-based neurosurgery is one of the most important pillars upon which to build decision management pathways. Effective delivery of care involves understanding the natural history of the disease and the evidence behind available treatment options. Neurosurgical Diseases: An Evidence-Based Approach to Guide Practice by esteemed neurosurgeons Leon T. Lai, Cristian Gragnaniello, and expert contributors covers cranial pathologies neurosurgeons commonly encounter in everyday practice. The book combines a structured approach to evidence-based neurosurgery with expert opinions, analysis of up-to-date clinical data, understanding of patient preferences and values, and firsthand experiences to facilitate translation of evidence into clinical practice. Twenty-seven consistently formatted chapters are each dedicated to a different disease state, including brain tumors, cerebrovascular disease, Cushing's disease, traumatic brain injury, trigeminal neuralgia, and normal pressure hydrocephalus. All chapters include an introduction, current statistics and data, natural history of the pathology, selected papers for further reading, procedural options and outcomes, and recommended treatment protocols from the authors. Key Features Key content summarized in reader-friendly bullets, diagrams, tables, and illustrative figures enhances acquisition of knowledge Discussion of new developments including treatment recommendations for primary and metastatic brain tumors Statistical data on cerebral aneurysm treatment outcomes and recommendations for treatment New protocols for treating head trauma, closed head injuries, and spontaneous intracranial hemorrhage This essential resource will help neurosurgical residents and junior neurosurgeons make challenging surgical treatment decisions for complex conditions, clearly and concisely and based on the best evidence.

Avery's Neonatology

Avery's Neonatology PDF Author: Mhairi G. MacDonald
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781746434
Category : Medical
Languages : en
Pages : 1866

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Book Description
Revised and updated by a new editorial team, the Sixth Edition of this text will remain the leading reference on the clinical care of the newborn. It provides complete, authoritative information on the biology of the newborn and the pathophysiology and management of diseases during the neonatal period. This edition has five new chapters on the role of telemedicine in neonatology, the impact of labor and delivery on the fetus, fetal determinants of adult disease, breast feeding, and control of breathing and apnea. Also included is a full-color insert illustrating key signs and symptoms, selected imaging techniques, and dermatologic conditions.

Family Medicine Obstetrics E-Book

Family Medicine Obstetrics E-Book PDF Author: Stephen D. Ratcliffe
Publisher: Elsevier Health Sciences
ISBN: 0323070825
Category : Medical
Languages : en
Pages : 734

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Book Description
Whether you offer comprehensive pregnancy care in your primary care facility, or provide prenatal and postpartum care, this book delivers the guidance you need to optimize health for both mothers and their babies. It covers all aspects of birth care, from preconception counseling and prenatal care, through labor and delivery (both low-risk and complicated), to postpartum care and the first month of life. The completely revised third edition includes the most up-to- date, evidence-based standards of care. It offers information that is patient centered, prevention oriented, educational, and sensitive to the care of the whole woman and her family. Features a reader-friendly outline/narrative format for ease of use in daily clinical practice. Describes how to care for patients with a wide range of medical conditions during pregnancy as well as pregnancy-related conditions. Takes a whole-family approach to maternity care, with discussions of maternal and paternal adjustment, marital adjustment, sibling adjustment, single-parent families, and return-to-work issues. Provides patient and family education materials on a full range of topics, from nutrition in pregnancy to breastfeeding. Features a section on alternative medicine in maternity care. Provides detailed instruction for a wide array of procedures, including cesarean delivery, perineal repair of simple and complex lacerations, circumcision, assisted deliveries, and amnioinfusion. A continued strong emphasis on evidence-based medicine includes an ongoing summary of Level A recommendations throughout the text. A new chapter summarizes practical applications of how to incorporate continuous quality improvement and enhanced medical safety into the maternity care setting. A new section details which immunizations can be used safely during pregnancy. A section on "Centering Pregnancy" discusses this new model of care and how it incorporates longitudinal group.

Neonatology: Clinical Practice and Procedures

Neonatology: Clinical Practice and Procedures PDF Author: Philip Sunshine
Publisher: McGraw-Hill Education / Medical
ISBN: 9780071763769
Category : Medical
Languages : en
Pages : 0

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Book Description
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Understand the fundamental principles of neonatology and learn evidence-based care strategies With coverage that strikes the perfect balance between proven management approaches and fundamental principles, this unique resource combines the benefits of a comprehensive neonatology textbook with a practical procedural guide. You will get a detailed step-by-step instruction on diagnosis, management, and treatment of acute problems of the newborn as organized by organ system, based on the highest level of evidence available, along with a thorough review of topics such as epidemiology, ethics, legal issues in the NICU, monitoring devices, fluid requirements, and enteral nutrition. Features A full-color presentation that includes hundreds of figures and tables An emphasis on proven care strategies for improved outcomes Detailed procedural instruction An organ-system approach when discussing neonatal disorders A practical approach to all topics with detailed management approaches and procedures Neonatology: Clinical Practice and Procedures will prove to be an outstanding refresher for any clinician involved in the diagnosis and management of newborn infants and a valuable instructional guide for junior staff and residents.

Fetal and Neonatal Neurology and Neurosurgery

Fetal and Neonatal Neurology and Neurosurgery PDF Author: Malcolm I. Levene
Publisher: Elsevier Health Sciences
ISBN: 0443104077
Category : Medical
Languages : en
Pages : 940

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Book Description
The definitive reference work on the developing brain from conception through the first year of life, this book provides specialists involved in the management of the fetus and the neonate with the latest information on the developmental neurology and pathology of the developing central nervous system.

Neonatal and Pediatric Liver and Metabolic Diseases

Neonatal and Pediatric Liver and Metabolic Diseases PDF Author: Manoj K. Ghoda
Publisher: Springer Nature
ISBN: 9811592314
Category : Medical
Languages : en
Pages : 254

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Book Description
This book is written to simplify complex topics of neonatal and pediatric liver and metabolic diseases which are encountered by clinicians on a day to day basis. Neonatal and early pediatric liver diseases are very much different from adult liver diseases. Most of them are either structural diseases or genetically modulated metabolic disorders affecting liver. They all look same; however the underlying etiology could be quite different. This book thoroughly covers various neonatal and pediatric liver and metabolic diseases through a unique clinical case based approach via a vast clinical experience of the author. The book presents more than 50 unique cases and presents real life learning scenario with various examples facilitating better understanding of the disease and the ways to analyze it. The book uses a simple language and presents line diagrams and algorithms facilitating learning. This book shall be a valuable resource for practicing general pediatricians, pediatric residents and gastroenterologists with involvement in pediatric liver and liver related metabolic diseases.