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Author: William R. Cullen
Publisher: Royal Society of Chemistry
ISBN: 0854043632
Category : Medical
Languages : en
Pages : 429
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Book Description
Sex, drugs, rocks, gold, murder, war, mass poisonings, the deaths of Napoleon, Tchaikovsky, Mozart, and others are all linked by one element - arsenic! Arsenic has been around since the beginning of time and the word has become a metaphor for poison with associated shock value. The general public are fearful of any possible exposure to it and yet it holds a certain dark and eerie fascination! The average person has only one idea about arsenic - it is poison - and this reputation has a sound base. Some arsenic compounds are very toxic and have been used with criminal intent from the time of the.
Author: William R. Cullen
Publisher: Royal Society of Chemistry
ISBN: 0854043632
Category : Medical
Languages : en
Pages : 429
Get Book Here
Book Description
Sex, drugs, rocks, gold, murder, war, mass poisonings, the deaths of Napoleon, Tchaikovsky, Mozart, and others are all linked by one element - arsenic! Arsenic has been around since the beginning of time and the word has become a metaphor for poison with associated shock value. The general public are fearful of any possible exposure to it and yet it holds a certain dark and eerie fascination! The average person has only one idea about arsenic - it is poison - and this reputation has a sound base. Some arsenic compounds are very toxic and have been used with criminal intent from the time of the.
Author: William R Cullen
Publisher: Royal Society of Chemistry
ISBN: 1847558607
Category : Science
Languages : en
Pages : 429
Get Book Here
Book Description
Sex, drugs, rocks, gold, murder, war, mass poisonings, the deaths of Napoleon, Tchaikovsky, Mozart, and others are all linked by one element - arsenic! Arsenic has been around since the beginning of time and the word has become a metaphor for poison with associated shock value. The general public are fearful of any possible exposure to it and yet it holds a certain dark and eerie fascination! The average person has only one idea about arsenic - it is poison - and this reputation has a sound base. Some arsenic compounds are very toxic and have been used with criminal intent from the time of the ancient Romans to the present day. Up until now, there has been no book that covers arsenic with such breadth. This book is a general appreciation of how much the element, arsenic, has become part of our lives in an entertaining style covering the years 1000 BC to the present day. The coverage of the chemistry, toxicology, and medicinal aspects is deliberately kept at a level for the general reader to understand. It covers the way in which this ubiquitous element and its compounds have influenced the lives of the people of the world. The author's objective in writing this book was not to elaborate on the vast chemistry of the element, but to try to reveal to the general reader how the element and its compounds have become embedded in our social fabric, for good and for ill. No other element comes close in this regard and he uses the word sociochemistry to describe this interface between society and chemistry. The book covers a broad range of topics including the use of arsenic in human medicine in many cultures from Chinese medicine to the beginning of chemotherapy. This peaked in the western world in the early 20th century, with Ehrlich's discovery of salvarsan, an arsenic-based cure for syphilis that gave rise to the field of chemotherapy. Salvarsan and related compounds were eventually displaced by antibiotics such as penicillin. Arsenic trioxide has staged a comeback, however, and is being used as a successful treatment for a form of leukemia. Other chapters cover arsenic compounds which were widely used in agriculture and wood preservation during the 20th century and their associated myths as well as arsenic compounds as chemical warfare agents and the resulting stockpile. The topic of arsenic in the environment is discussed in depth - arsenic is all around us - in our soil, our water, and our food, and our bodies have adapted to its presence and it does not usually pose a problem. However, the natural presence of high concentrations of arsenic in drinking water currently threatens the lives of millions of people in India, Bangladesh, Mexico and elsewhere. It also covers mining and pesticide manufacturing which can lead to high local arsenic concentrations in soils, slag heaps and mine tailings which, when located close to human activities, can produce human health risks. Other chapters cover a variety of topics including: " A proposed connection between arsenic and Cot Death (SIDS) which caused panic " The high concentration of arsenic in kelp products-is this harmful? " What about the 237,000 tonnes of arsenic trioxide stored in a mine in Canada? " How toxic is arsenic anyway, and how do you assess the risks of exposure? " How did Napoleon die? These and many other topics are addressed at a level that will result in understanding without delving into too much technical detail or requiring a degree in chemistry. Essential reading for everyone with a general interest in science, this illuminating text covers a broad range of topics.
Author: Hongzhe Sun
Publisher: John Wiley & Sons
ISBN: 0470976225
Category : Science
Languages : en
Pages : 379
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Book Description
Arsenic, antimony and bismuth, three related elements of group 15, are all found in trace quantities in nature and have interesting biological properties and uses. While arsenic is most well known as a poison - and indeed the contamination of groundwater by arsenic is becoming a major health problem in Asia - it also has uses for the treatment of blood cancer and has long been used in traditional chinese medicine. Antimony and bismuth compounds are used in the clinic for the treatment of parasitic and bacterial infections. Biological Chemistry of Arsenic, Antimony and Bismuth is an essential overview of the biological chemistry of these three elements, with contributions from an international panel of experts. Topics covered include: chemistry of As, Sb and Bi biological chemistry of arsenic biological chemistry of Sb and Bi arsenic and antimony speciation in environmental and biological samples arsenic in traditional chinese medicine arsenic in aquifers biomethylation of As, Sb and Bi uptake of metalloids by cells bismuth complexes of porphyrins and their potential in medical applications Helicobacter pylori and bismuth metabolism of arsenic trioxide in blood of the acute promyelocytic leukemia patients anticancer properties of As, Sb and Bi radio-Bi in cancer therapy genotoxicity of As, Sb and Bi metallomics as a new technique for As, Sb and Bi metalloproteomics for As, Sb and Bi Biological Chemistry of Arsenic, Antimony and Bismuth conveys the essential aspects of the bioinorganic chemistry of these three elements, making this book a valuable complement to more general bioinorganic chemistry texts and more specialized topical reviews. It will find a place on the bookshelves of practitioners, researchers and students working in bioinorganic chemistry and medicinal chemistry.
Author: Narayan Chakrabarty
Publisher: CRC Press
ISBN: 1040073522
Category : Medical
Languages : en
Pages : 499
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Book Description
The most talked about metalloid in the modern world, arsenic affects the liver, kidney, and lungs; leads to cardiovascular diseases, cancer, and diabetes; and may cause blindness with long-time exposure. With naturally occurring arsenic boosted by mining and other industrial processes contaminating soil and drinking water, arsenic toxicity is a maj
Author: David Arnold
Publisher: Cambridge University Press
ISBN: 1107126975
Category : History
Languages : en
Pages : 253
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Book Description
An analysis of the challenge that India's poison culture posed for colonial rule and toxicology's creation of a public role for science.
Author: Joanne M. Santini
Publisher: CRC Press
ISBN: 1136319549
Category : Science
Languages : en
Pages : 207
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Book Description
Up to 200 million people in 70 countries are at risk from drinking water contaminated with arsenic, which is a major cause of chronic debilitating illnesses and fatal cancers. Until recently little was known about the mobility of arsenic, and how redox transformations determined its movement into or out of water supplies. Although human activities contribute to the release of arsenic from minerals, it is now clear that bacteria are responsible for most of the redox transformation of arsenic in the environment. Bacterial oxidation of arsenite (to the less mobile arsenate) has been known since 1918, but it was not until 2000 that a bacterium was shown to gain energy from this process. Since then a wide range of arsenite-oxidizing bacteria have been isolated, including aerobes and anaerobes; heterotrophs and autotrophs; thermophiles, mesophiles and psychrophiles. This book reviews recent advances in the study of such bacteria. After a section on background—geology and health issues—the main body of the book concerns the cellular machinery of arsenite oxidation. It concludes by examining possible applications. Topics treated are: The geology and cycling of arsenic Arsenic and disease Arsenite oxidation: physiology, enzymes, genes, and gene regulation. Community genomics and functioning, and the evolution of arsenite oxidation Microbial arsenite oxidation in bioremediation Biosensors for arsenic in drinking water and industrial effluents
Author: Raymond Poon
Publisher: World Scientific Publishing Company
ISBN: 9814412953
Category : Medical
Languages : en
Pages : 275
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Book Description
This unique volume provides in layman's terms, without sacrificing scientific facts, the health hazards and potential dangers of naturally occurring substances that are around us everyday. The comprehensive coverage includes compounds (e.g. arsenic, lead), gases (e.g. hydrogen sulphide, ozone) and all forms of natural radiations (e.g. heat, radon). Readers will find this book both informative and entertaining because facts and important data are introduced and interpreted in the form of history, stories and scientific summaries. Each chapter concludes with a practical guide that readers will find useful.Harmful Naturally Occurring Substance and Radiation, which is fully referenced with up-to-date articles, may be used as a textbook for undergraduates and as an introductory textbook for post-graduates in biochemistry, environmental science, toxicology, medical science, and health care. People interested in personal and public health and earth issues will find this book a thought-provoking and revealing read. The book may also be a source of information for policy makers, public health officials, city planners and environmental engineers.
Author: Ines Weizman
Publisher: Routledge
ISBN: 1317700988
Category : Architecture
Languages : en
Pages : 322
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Book Description
Architecture and the Paradox of Dissidence maps out and expands upon the methodologies of architectural action and reinvigorates the concept of dissent within the architectural field. It expands the notion of dissidence to other similar practices and strategies of resistance, in a variety of historical and geographical contexts.The book also discusses how the gestures and techniques of past struggles, as well as ‘dilemmas’ of working in politically suppressive regimes, can help to inform those of today. This collection of essays from expert scholars demonstrates the multiple responses to this subject, the potential and dangers of dissidence, and thus constructs a robust lexicon of concepts that will point to possible ways forward for politically and theoretically committed architects and practitioners.
Author: John Parascandola
Publisher: Potomac Books, Inc.
ISBN: 1597977039
Category : Medical
Languages : en
Pages : 209
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Book Description
For centuries, arsenic's image as a poison has been inextricably tied to images of foul play. In King of Poisons, John Parascandola examines the surprising history of this deadly element. From Gustave Flaubert to Dorothy Sayers, arsenic has long held a place in the literary realm as an instrument of murder and suicide. It was delightfully used as a source of comedy in the famous play Arsenic and Old Lace. But as Parascandola shows, arsenic has had a number of surprising real-world applications. It was frequently found in such common items as wallpaper, paint, cosmetics, and even candy, and its use in medical treatments was widespread. American ambassador Clare Boothe Luce suffered from exposure to arsenical paint in her study, and Napoleon's death has long been speculated to be the result of accidental or intentional poisoning. But arsenic poisoning is still a public menace. In the neighborhood surrounding American University in Washington, D.C., the army has undertaken a massive cleanup of artillery shells and bottles containing chemical warfare agents such as arsenical lewisite after a number of workmen and residents became ill. Arsenic contamination of the water supply in Bangladesh and in West Bengal, India, is a major public health problem today as well. From murder to crime fiction, from industrial toxin to chemical warfare, arsenic remains a powerful force in modern life.
Author: Dharmendra Kumar Gupta
Publisher: Springer
ISBN: 3319543563
Category : Science
Languages : en
Pages : 225
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Book Description
This book provides an overview to researchers, graduate, and undergraduate students, as well as academicians who are interested in arsenic. It covers human health risks and established cases of human ailments and sheds light on prospective control measures, both biological and physico-chemical. Arsenic (As) is a widely distributed element in the environment having no known useful physiological function in plants or animals. Historically, this metalloid has been known to be used widely as a poison. Effects of arsenic have come to light in the past few decades due to its increasing contamination in several parts of world, with the worst situation being in Bangladesh and West Bengal, India. The worrying issue is the ingestion of arsenic through water and food and associated health risks due to its carcinogenic and neurotoxic nature. The impact of the problem is widespread, and it has led to extensive research on finding both the causes and solutions. These attempts have allowed us to understand the various probable causes of arsenic contamination in the environment, and at the same time, have provided a number of possible solutions. It is reported that more than 200 mineral species contain As. Generally, As binds with iron and sulfur to form arsenopyrite. According to one estimate from the World Health Organization (WHO), contextual levels of As in soil ranges from 1 to 40 mg kg-1. Arsenic toxicity is related to its oxidation state which is present in the medium. As is a protoplastic toxin, due to its consequence on sulphydryl group it interferes in cell enzymes, cell respiration and in mitosis. Exposure of As may occur to humans via several industries, such as refining or smelting of metal ores, microelectronics, wood preservation, battery manufacturing, and also to those who work in power plants that burn arsenic-rich coal.
