IPCS Risk Assessment Terminology

IPCS Risk Assessment Terminology PDF Author: International Program on Chemical Safety
Publisher: World Health Organization
ISBN: 9241562676
Category : Medical
Languages : en
Pages : 126

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Book Description
A joint project of IPCS/OECD. In two parts: Part 1: IPCS/OECD Key Generic Terms used in Chemical Hazard/Risk Assessment. Part 2: IPCS Glossary of Key Exposure Assessment Terminology. IPCS project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals

IPCS Risk Assessment Terminology

IPCS Risk Assessment Terminology PDF Author: International Program on Chemical Safety
Publisher: World Health Organization
ISBN: 9241562676
Category : Medical
Languages : en
Pages : 126

Get Book Here

Book Description
A joint project of IPCS/OECD. In two parts: Part 1: IPCS/OECD Key Generic Terms used in Chemical Hazard/Risk Assessment. Part 2: IPCS Glossary of Key Exposure Assessment Terminology. IPCS project on the Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals

Science and Decisions

Science and Decisions PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309120462
Category : Political Science
Languages : en
Pages : 422

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Book Description
Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Regulatory Toxicology

Regulatory Toxicology PDF Author: Franz-Xaver Reichl
Publisher: Springer
ISBN: 9783642353734
Category : Medical
Languages : en
Pages : 0

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Book Description
This book will be written by experts for professionals, scientists and all those involved in toxicological data generation and decision-making. It is the updated and expanded version of a monograph published in German in 2004. Chemical safety is regulated on various levels including production, storage, transport, handling, disposal or labelling. This book deals comprehensively with the safety-ensuring methods and concepts employed by regulatory agencies, industry and academics. Toxicologists use experimental and scientific approaches for data collection, e.g. about chemical hazards, physicochemical features or toxicokinetics. The respective experimental methods are described in the book. Toxicologists also deal with much insecurity in the exposure and effect scenarios during risk assessment. To overcome these, they have different extrapolation methods and estimation procedures at their disposal. The book describes these methods in an accessible manner. Differing concepts from one regulation area to another are also covered. Reasons and consequences become evident when reading the book. Altogether, the book Regulatory Toxicology will serve as an excellent reference.

Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals

Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030907553X
Category : Political Science
Languages : en
Pages : 225

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Book Description
Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals contains a detailed and comprehensive methodology for developing acute exposure guideline levels (AEGLs) for toxic substances from inhalation exposures. The book provides guidance on what documents and databases to use, toxicity endpoints that need to be evaluated, dosimetry corrections from animal to human exposures, selection of appropriate uncertainty factors to address the variability between animals and humans and within the human population, selection of modifying factors to address data deficiencies, time scaling, and quantitative cancer risk assessment. It also contains an example of a summary of a technical support document and an example of AEGL derivation. This book will be useful to persons in the derivation of levels from other exposure routesâ€"both oral and dermalâ€"as well as risk assessors in the government, academe, and private industry.

Toxicological Risk Assessment of Chemicals

Toxicological Risk Assessment of Chemicals PDF Author: Elsa Nielsen
Publisher: CRC Press
ISBN: 1420006940
Category : Medical
Languages : en
Pages : 450

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Book Description
Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk

Nanomaterials in Waste Streams Current Knowledge on Risks and Impacts

Nanomaterials in Waste Streams Current Knowledge on Risks and Impacts PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264249753
Category :
Languages : en
Pages : 98

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Book Description
This report provides a literature review on four specific waste treatment processes (recycling, incineration, landfilling and wastewater treatment).

Urban Water Security: Managing Risks

Urban Water Security: Managing Risks PDF Author: Blanca Jimenez Cisneros
Publisher: CRC Press
ISBN: 0203881621
Category : Science
Languages : en
Pages : 348

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Book Description
Understanding the impacts of urbanization on the urban water cycle and managing the associated health risks demand adequate strategies and measures. Health risks associated with urban water systems and services include the microbiological and chemical contamination of urban waters and outbreak of water-borne diseases, mainly due to poor water and s

Reducing, Refining and Replacing the Use of Animals in Toxicity Testing

Reducing, Refining and Replacing the Use of Animals in Toxicity Testing PDF Author: Dave Allen
Publisher: Royal Society of Chemistry
ISBN: 1849737924
Category : Science
Languages : en
Pages : 385

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Book Description
Toxicity testing is used to assess the safety or hazards presented by substances such as industrial chemicals, consumer products, and pharmaceuticals. At present, many methods involve laboratory animals. Alternative procedures, some involving human cell-based technologies, are now being developed which reduce, refine, or replace animal usage and minimize the pain and distress caused. These new tests must protect public health and the environment at least as well as currently accepted methods. This book describes the ever-expanding "toolbox" of methods available to assess toxicity. Such techniques often result from our growing understanding of the biochemical and cellular pathways that mediate toxicity mechanisms. This permits evaluations of information generated from several sources to generate a "weight of evidence". By combining in silico, in vitro, and ex vivo methods with technologies that rely on biochemical- and cell-based in vitro assays, toxicologists are developing mechanistically based alternatives to live animal experimentation. This text also explores the complexities associated with adequate validation, and the assessment of test reliability and relevance. It provides an essential reference source for postgraduates, academics and industrialists working in this rapidly changing area.

Engineering Tools for Environmental Risk Management

Engineering Tools for Environmental Risk Management PDF Author: Katalin Gruiz
Publisher: CRC Press
ISBN: 1315778777
Category : Science
Languages : en
Pages : 579

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Book Description
Chemical substances, physical agents and built structures exhibit various types of hazard due to their inherent toxic, mutagenic, carcinogenic, reprotoxic and sensitizing character or damaging to the immune and hormone system. The first steps in managing an environment contaminated by chemical substances are characterization of hazards and quantifi

Introduction to Sustainability Analytics

Introduction to Sustainability Analytics PDF Author: Raghavan (Ram) Ramanan
Publisher: CRC Press
ISBN: 1351650939
Category : Business & Economics
Languages : en
Pages : 293

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Book Description
The roles of corporate and public stewards and the nature of their social contract with society have been changing over the past two centuries, and those changes have accelerated in recent decades. Moreover, with increasing focus on sustainability factors from the marketplace (regulators, investors, financiers, and consumers), corporate sustainability disclosure is shifting from voluntary to vital. Corporate and public stewards are now responsible for their performance and services from cradle-to-grave: they must properly manage corporate social responsibility and integrate it into their global strategies, rather than consider it as merely a moral obligation or a risk/reputation management exercise. Sustainability analytics, the critical link between sustainability and business strategy, helps professionals track, trend, and transform sustainability information into actionable insights across the value chain and life cycle, to enhance their sustainability performance and its disclosure. This book, Introduction to Sustainability Analytics, provides corporate and public stewards with a comprehensive understanding of how to determine which sustainability metrics are material to them and relevant to their business, and how to incorporate them into corporate strategy, resource allocation, and prioritization. Focusing on practical decision-making needs, it explains how to value and prioritize initiatives, and how to best allocate necessary resources through several real case studies and practical examples. Features: Examines pressing issues such as climate change, water scarcity, and environmental justice Explains how to develop a business case and global strategy for social responsibility Includes both corporate and public policy perspectives on sustainability economics Covers emerging regulations on sustainability disclosure and responsible investing