Introductory Review on Sirtuins in Biology, Aging, and Disease PDF Download
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Author: Leonard Guarente
Publisher: Academic Press
ISBN: 012813500X
Category : Science
Languages : en
Pages : 222
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Book Description
Introductory Review on Sirtuins in Biology and Disease provides key insights for scientists and advanced students who need to understand sirtuins and the current research in this field. This book is ideal for pharmaceutical companies as they develop novel targets using sirtuins for metabolic diseases, cancer and neurodegenerative illnesses. Sirtuins are a diverse family of proteins, with several members in mammals. The functional diversity of sirtuins is rather broad, and they have been implicated in various central biological processes. Thus, they are also highly relevant in the context of various human diseases, from cancer to neurodegeneration. Covers both the general and specific aspects of sirtuin proteins and their role in biology, aging and disease Presents a top quality collection of leading experts who contribute on a wide range of sirtuin-related topics Ideal resource for pharmaceutical companies as they develop novel targets using sirtuins for metabolic diseases, cancer and neurodegenerative illnesses
Author: Leonard Guarente
Publisher: Academic Press
ISBN: 012813500X
Category : Science
Languages : en
Pages : 222
Get Book Here
Book Description
Introductory Review on Sirtuins in Biology and Disease provides key insights for scientists and advanced students who need to understand sirtuins and the current research in this field. This book is ideal for pharmaceutical companies as they develop novel targets using sirtuins for metabolic diseases, cancer and neurodegenerative illnesses. Sirtuins are a diverse family of proteins, with several members in mammals. The functional diversity of sirtuins is rather broad, and they have been implicated in various central biological processes. Thus, they are also highly relevant in the context of various human diseases, from cancer to neurodegeneration. Covers both the general and specific aspects of sirtuin proteins and their role in biology, aging and disease Presents a top quality collection of leading experts who contribute on a wide range of sirtuin-related topics Ideal resource for pharmaceutical companies as they develop novel targets using sirtuins for metabolic diseases, cancer and neurodegenerative illnesses
Author: Miguel Morales
Publisher: Manning Publications
ISBN: 1617295450
Category : Computers
Languages : en
Pages : 470
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Book Description
Grokking Deep Reinforcement Learning uses engaging exercises to teach you how to build deep learning systems. This book combines annotated Python code with intuitive explanations to explore DRL techniques. You’ll see how algorithms function and learn to develop your own DRL agents using evaluative feedback. Summary We all learn through trial and error. We avoid the things that cause us to experience pain and failure. We embrace and build on the things that give us reward and success. This common pattern is the foundation of deep reinforcement learning: building machine learning systems that explore and learn based on the responses of the environment. Grokking Deep Reinforcement Learning introduces this powerful machine learning approach, using examples, illustrations, exercises, and crystal-clear teaching. You'll love the perfectly paced teaching and the clever, engaging writing style as you dig into this awesome exploration of reinforcement learning fundamentals, effective deep learning techniques, and practical applications in this emerging field. Purchase of the print book includes a free eBook in PDF, Kindle, and ePub formats from Manning Publications. About the technology We learn by interacting with our environment, and the rewards or punishments we experience guide our future behavior. Deep reinforcement learning brings that same natural process to artificial intelligence, analyzing results to uncover the most efficient ways forward. DRL agents can improve marketing campaigns, predict stock performance, and beat grand masters in Go and chess. About the book Grokking Deep Reinforcement Learning uses engaging exercises to teach you how to build deep learning systems. This book combines annotated Python code with intuitive explanations to explore DRL techniques. You’ll see how algorithms function and learn to develop your own DRL agents using evaluative feedback. What's inside An introduction to reinforcement learning DRL agents with human-like behaviors Applying DRL to complex situations About the reader For developers with basic deep learning experience. About the author Miguel Morales works on reinforcement learning at Lockheed Martin and is an instructor for the Georgia Institute of Technology’s Reinforcement Learning and Decision Making course. Table of Contents 1 Introduction to deep reinforcement learning 2 Mathematical foundations of reinforcement learning 3 Balancing immediate and long-term goals 4 Balancing the gathering and use of information 5 Evaluating agents’ behaviors 6 Improving agents’ behaviors 7 Achieving goals more effectively and efficiently 8 Introduction to value-based deep reinforcement learning 9 More stable value-based methods 10 Sample-efficient value-based methods 11 Policy-gradient and actor-critic methods 12 Advanced actor-critic methods 13 Toward artificial general intelligence
Author: David Gough
Publisher: SAGE
ISBN: 1446289362
Category : Literary Criticism
Languages : en
Pages : 382
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Book Description
This timely, engaging book provides an overview of the nature, logic, diversity and process of undertaking systematic reviews as part of evidence informed decision making. A focused, accessible and technically up-to-date book, it covers the full breadth of approaches to reviews from statistical meta analysis to meta ethnography. It is ideal for anyone undertaking their own systematic review - providing all the necessary conceptual and technical background needed to make a good start on the process. The content is divided into five clear sections: • Approaches to reviewing • Getting started • Gathering and describing research • Appraising and synthesising data • Making use of reviews/models of research use. Easy to read and logically structured, this book is essential reading for anyone doing systematic reviews. David Gough is Professor of Evidence Informed Policy and Practice and Director of SSRU and its EPPI-Centre and Co-Editor of the journal Evidence & Policy. Sandy Oliver is Professor of Public Policy and Deputy Director of SSRU and its EPPI-Centre. James Thomas is Reader in Social Policy, Assistant Director of SSRU and Associate Direcctor of the EPPI-Centre.
Author: Paul Miller
Publisher: MIT Press
ISBN: 0262347563
Category : Science
Languages : en
Pages : 405
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Book Description
A textbook for students with limited background in mathematics and computer coding, emphasizing computer tutorials that guide readers in producing models of neural behavior. This introductory text teaches students to understand, simulate, and analyze the complex behaviors of individual neurons and brain circuits. It is built around computer tutorials that guide students in producing models of neural behavior, with the associated Matlab code freely available online. From these models students learn how individual neurons function and how, when connected, neurons cooperate in a circuit. The book demonstrates through simulated models how oscillations, multistability, post-stimulus rebounds, and chaos can arise within either single neurons or circuits, and it explores their roles in the brain. The book first presents essential background in neuroscience, physics, mathematics, and Matlab, with explanations illustrated by many example problems. Subsequent chapters cover the neuron and spike production; single spike trains and the underlying cognitive processes; conductance-based models; the simulation of synaptic connections; firing-rate models of large-scale circuit operation; dynamical systems and their components; synaptic plasticity; and techniques for analysis of neuron population datasets, including principal components analysis, hidden Markov modeling, and Bayesian decoding. Accessible to undergraduates in life sciences with limited background in mathematics and computer coding, the book can be used in a “flipped” or “inverted” teaching approach, with class time devoted to hands-on work on the computer tutorials. It can also be a resource for graduate students in the life sciences who wish to gain computing skills and a deeper knowledge of neural function and neural circuits.
Author: United States. Bureau of Foreign Commerce
Publisher:
ISBN:
Category :
Languages : en
Pages : 258
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Book Description
Author: Erwin Kreyszig
Publisher: John Wiley & Sons
ISBN: 0471504599
Category : Mathematics
Languages : en
Pages : 706
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Book Description
KREYSZIG The Wiley Classics Library consists of selected books originally published by John Wiley & Sons that have become recognized classics in their respective fields. With these new unabridged and inexpensive editions, Wiley hopes to extend the life of these important works by making them available to future generations of mathematicians and scientists. Currently available in the Series: Emil Artin Geometnc Algebra R. W. Carter Simple Groups Of Lie Type Richard Courant Differential and Integrai Calculus. Volume I Richard Courant Differential and Integral Calculus. Volume II Richard Courant & D. Hilbert Methods of Mathematical Physics, Volume I Richard Courant & D. Hilbert Methods of Mathematical Physics. Volume II Harold M. S. Coxeter Introduction to Modern Geometry. Second Edition Charles W. Curtis, Irving Reiner Representation Theory of Finite Groups and Associative Algebras Nelson Dunford, Jacob T. Schwartz unear Operators. Part One. General Theory Nelson Dunford. Jacob T. Schwartz Linear Operators, Part Two. Spectral Theory—Self Adjant Operators in Hilbert Space Nelson Dunford, Jacob T. Schwartz Linear Operators. Part Three. Spectral Operators Peter Henrici Applied and Computational Complex Analysis. Volume I—Power Senes-lntegrauon-Contormal Mapping-Locatvon of Zeros Peter Hilton, Yet-Chiang Wu A Course in Modern Algebra Harry Hochstadt Integral Equations Erwin Kreyszig Introductory Functional Analysis with Applications P. M. Prenter Splines and Variational Methods C. L. Siegel Topics in Complex Function Theory. Volume I —Elliptic Functions and Uniformizatton Theory C. L. Siegel Topics in Complex Function Theory. Volume II —Automorphic and Abelian Integrals C. L. Siegel Topics In Complex Function Theory. Volume III —Abelian Functions & Modular Functions of Several Variables J. J. Stoker Differential Geometry
Author: Marcel Danesi
Publisher: Rowman & Littlefield
ISBN: 1442217839
Category : Language Arts & Disciplines
Languages : en
Pages : 287
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Book Description
Popular Culture: Introductory Perspectives seeks to define pop culture by exploring the ways that it fulfills our human desire for meaning.The second edition investigates current contexts for popular culture, including the rise of the digital global village through new technology and offers up-to-date examples that connect with today's students."
Author: Desmond Michael Allison
Publisher: World Scientific Publishing Company
ISBN: 9813102845
Category : Language Arts & Disciplines
Languages : en
Pages : 267
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Book Description
The book brings together two related fields — language testing and language programme evaluation — in a way that no single introductory text has done, and seeks to encourage closer relations between the two in both academic curricula and professional practice. It introduces readers not just to basic concepts, but to some of the major social, educational and research concerns and activities that characterise language testing and evaluation.The book can serve either as a basic text for a taught course, or as independent reading in self-study mode. All chapters include suggestions for further reading, and discussions frequently point towards possible explorations in classroom research and practice. A glossary of key concepts and a select annotated bibliography are provided.
Author: Various
Publisher: Good Press
ISBN:
Category : History
Languages : en
Pages : 492
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Book Description
"Famous Reviews, Selected and Edited with Introductory Notes by R. Brimley Johnson" by Various. Published by Good Press. Good Press publishes a wide range of titles that encompasses every genre. From well-known classics & literary fiction and non-fiction to forgotten−or yet undiscovered gems−of world literature, we issue the books that need to be read. Each Good Press edition has been meticulously edited and formatted to boost readability for all e-readers and devices. Our goal is to produce eBooks that are user-friendly and accessible to everyone in a high-quality digital format.
Author: Richard A. Silverman
Publisher: Courier Corporation
ISBN: 0486318524
Category : Mathematics
Languages : en
Pages : 402
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Book Description
Shorter version of Markushevich's Theory of Functions of a Complex Variable, appropriate for advanced undergraduate and graduate courses in complex analysis. More than 300 problems, some with hints and answers. 1967 edition.
