Interpreting Epidemiologic Evidence

Interpreting Epidemiologic Evidence PDF Author: David A. Savitz
Publisher: Oxford University Press
ISBN: 0199747695
Category : Medical
Languages : en
Pages : 336

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Book Description
Evaluating the strength or persuasiveness of epidemiologic evidence is inherently challenging, both for those new to the field and for experienced researchers. There are a myriad of potential biases to consider, but little guidance about how to asses the likely impact on study results. This book offers a strategy for assessing epidemiologic research findings, explicitly describing the goals and products of epidemiologic research in order to better evaluate it successes and limitations. The focus throughout is on practical tools for making optimal use of available data to assess whether hypothesized biases are operative and to anticipate concerns at the point of study design in order to ensure that needed information is generated. Specific tools for assessing the presence and impact of selection bias in both cohort and case-control studies, bias from non-response, confounding, exposure measurement error, disease measurement error, and random error are identified and evaluated. The potential value of each approach as well as its limitations are discussed, using examples from the published literature. Such information should help those who generate and interpret epidemiologic research to apply methodological principles more effectively to substantive issues, leading to a more accurate appraisal of the current evidence and greater clarity about research needs.

Interpreting Epidemiologic Evidence

Interpreting Epidemiologic Evidence PDF Author: David A. Savitz
Publisher: Oxford University Press
ISBN: 0199747695
Category : Medical
Languages : en
Pages : 336

Get Book Here

Book Description
Evaluating the strength or persuasiveness of epidemiologic evidence is inherently challenging, both for those new to the field and for experienced researchers. There are a myriad of potential biases to consider, but little guidance about how to asses the likely impact on study results. This book offers a strategy for assessing epidemiologic research findings, explicitly describing the goals and products of epidemiologic research in order to better evaluate it successes and limitations. The focus throughout is on practical tools for making optimal use of available data to assess whether hypothesized biases are operative and to anticipate concerns at the point of study design in order to ensure that needed information is generated. Specific tools for assessing the presence and impact of selection bias in both cohort and case-control studies, bias from non-response, confounding, exposure measurement error, disease measurement error, and random error are identified and evaluated. The potential value of each approach as well as its limitations are discussed, using examples from the published literature. Such information should help those who generate and interpret epidemiologic research to apply methodological principles more effectively to substantive issues, leading to a more accurate appraisal of the current evidence and greater clarity about research needs.

Interpreting Epidemiologic Evidence

Interpreting Epidemiologic Evidence PDF Author: David A. Savitz
Publisher: Oxford University Press
ISBN: 0190243775
Category : Medical
Languages : en
Pages : 241

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Book Description
Evaluating the strength of epidemiologic evidence is inherently challenging, both for those new to the field and for experienced researchers. This book offers a strategy for assessing epidemiologic research findings, explicitly describing the goals and products of research

Interpreting Epidemiologic Evidence

Interpreting Epidemiologic Evidence PDF Author: David A. Savitz
Publisher: Oxford University Press, USA
ISBN: 019510840X
Category : Medical
Languages : en
Pages : 336

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Book Description
This book focuses on practical tools for making optimal use of available data to assess epidemiologic study findings. Includes: selection bias, confounding, measurement and classification of disease and exposure, random error and integration of evidence across studies.

Concepts of Epidemiology

Concepts of Epidemiology PDF Author: Raj S. Bhopal
Publisher: Oxford University Press
ISBN: 0198739680
Category : Medical
Languages : en
Pages : 481

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Book Description
First edition published in 2002. Second edition published in 2008.

Interpreting Epidemiologic Evidence

Interpreting Epidemiologic Evidence PDF Author: David A. Savitz
Publisher: Oxford University Press
ISBN: 0190243783
Category : Medical
Languages : en
Pages : 241

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Book Description
Epidemiology, the so-called "science of public health," has undergone a boom in the last decade as public interest and engagement in population health has skyrocketed. While this boom has done much to spark advances in the technology of epidemiology, it has also made it harder for those who want to use epidemiology to guide policy and clinical practice to fully appreciate the meaning of the research findings. Interpreting Epidemiologic Evidence offers those who have had an introductory course in epidemiology the knowledge they need to make clear connections from research findings to practical applications. Written in clear and lively prose, it empowers students at all levels to evaluate a study's design, implementation, and ultimate findings, giving the guidance needed to apply the information appropriately. Liberal use of practical examples serves both to illustrate core concepts and to motivate readers to think critically about the causal connections that population health studies aim to explore. Completely revised and updated, this new edition of Interpreting Epidemiologic Evidence is an invaluable core text for both epidemiologists in training and practitioners across other disciplines with even an introductory knowledge of epidemiology.

Analysis of Cancer Risks in Populations Near Nuclear Facilities

Analysis of Cancer Risks in Populations Near Nuclear Facilities PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309255716
Category : Medical
Languages : en
Pages : 424

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Book Description
In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.

Interpreting Epidemiologic Evidence

Interpreting Epidemiologic Evidence PDF Author: David A. Savitz
Publisher:
ISBN:
Category : Electronic book
Languages : en
Pages : 321

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Book Description
"Evaluating the strength of epidemiologic evidence is inherently challenging, both for those new to the field and for experienced researchers. This book offers a strategy for assessing epidemiologic research findings, explicitly describing the goals and products of research."--[Source inconnue].

Health Risks from Exposure to Low Levels of Ionizing Radiation

Health Risks from Exposure to Low Levels of Ionizing Radiation PDF Author: Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Publisher: National Academies Press
ISBN: 0309133343
Category : Science
Languages : en
Pages : 422

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Book Description
This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.

Epidemiology by Design

Epidemiology by Design PDF Author: Daniel Westreich
Publisher:
ISBN: 0190665769
Category : Medical
Languages : en
Pages : 241

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Book Description
A (LONG OVERDUE) CAUSAL APPROACH TO INTRODUCTORY EPIDEMIOLOGY Epidemiology is recognized as the science of public health, evidence-based medicine, and comparative effectiveness research. Causal inference is the theoretical foundation underlying all of the above. No introduction to epidemiology is complete without extensive discussion of causal inference; what's missing is a textbook that takes such an approach. Epidemiology by Design takes a causal approach to the foundations of traditional introductory epidemiology. Through an organizing principle of study designs, it teaches epidemiology through modern causal inference approaches, including potential outcomes, counterfactuals, and causal identification conditions. Coverage in this textbook includes: � Introduction to measures of prevalence and incidence (survival curves, risks, rates, odds) and measures of contrast (differences, ratios); the fundamentals of causal inference; and principles of diagnostic testing, screening, and surveillance � Description of three key study designs through the lens of causal inference: randomized trials, prospective observational cohort studies, and case-control studies � Discussion of internal validity (within a sample), external validity, and population impact: the foundations of an epidemiologic approach to implementation science For first-year graduate students and advanced undergraduates in epidemiology and public health fields more broadly, Epidemiology by Design offers a rigorous foundation in epidemiologic methods and an introduction to methods and thinking in causal inference. This new textbook will serve as a foundation not just for further study of the field, but as a head start on where the field is going.

Reference Manual on Scientific Evidence

Reference Manual on Scientific Evidence PDF Author:
Publisher:
ISBN:
Category : Evidence, Expert
Languages : en
Pages : 652

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Book Description