Physiological and Clinical Aspects of Short-Chain Fatty Acids

Physiological and Clinical Aspects of Short-Chain Fatty Acids PDF Author: John H. Cummings
Publisher: Cambridge University Press
ISBN: 9780521616133
Category : Medical
Languages : en
Pages : 602

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Book Description
This is the first comprehensive volume to look at the importance of short-chain fatty acids in digestion, the function of the large intestine and their role in human health. Short-chain fatty acids are the major product of bacterial fermentation of dietary carbohydrates in the human and animal large intestine. They represent the major end products of digestive processes occurring in the caecum and large intestine. As such, they form an important dietary component and it is increasingly recognised that they may have a significant role in protecting against large bowel cancer and in metabolism. Prepared by an international team of contributors who are at the forefront of this area of research, this volume will be an essential source of reference for gastroenterologists, nutritionists and others active in this area.

Physiological and Clinical Aspects of Short-Chain Fatty Acids

Physiological and Clinical Aspects of Short-Chain Fatty Acids PDF Author: John H. Cummings
Publisher: Cambridge University Press
ISBN: 9780521616133
Category : Medical
Languages : en
Pages : 602

Get Book Here

Book Description
This is the first comprehensive volume to look at the importance of short-chain fatty acids in digestion, the function of the large intestine and their role in human health. Short-chain fatty acids are the major product of bacterial fermentation of dietary carbohydrates in the human and animal large intestine. They represent the major end products of digestive processes occurring in the caecum and large intestine. As such, they form an important dietary component and it is increasingly recognised that they may have a significant role in protecting against large bowel cancer and in metabolism. Prepared by an international team of contributors who are at the forefront of this area of research, this volume will be an essential source of reference for gastroenterologists, nutritionists and others active in this area.

The Gut Microbiome in Health and Disease

The Gut Microbiome in Health and Disease PDF Author: Dirk Haller
Publisher: Springer
ISBN: 3319905457
Category : Medical
Languages : en
Pages : 355

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Book Description
The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

Immune-deficient Animals in Biomedical Research

Immune-deficient Animals in Biomedical Research PDF Author: Jørgen Rygaard
Publisher: S. Karger AG (Switzerland)
ISBN:
Category : Medical
Languages : en
Pages : 444

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Book Description


Interaction between the Gut Flora and Immunity in Intestinal Diseases

Interaction between the Gut Flora and Immunity in Intestinal Diseases PDF Author: Yating Li
Publisher: Frontiers Media SA
ISBN: 2832551580
Category : Medical
Languages : en
Pages : 160

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Book Description
The composition of gut microbiota plays a critical role in maintaining the host's health, particularly in regulating immune homeostasis and the intestinal immune response. A massive effort has pointed to the importance of these interactions in various intestinal diseases like colorectal cancer (CRC), irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD). Microbiome influences the formation of key components of both the innate and adaptive immune systems, while the immune system is responsible for regulating and maintaining the symbiotic relationship between the host and microbes. Currently, the crosstalk between gut flora and host immunity is not fully revealed in both homeostasis maintenance and disease development. Hence detailed mechanistic studies are needed to further explore the microbial manipulation on host immunity as well as the immune response to microbiome dysbiosis in intestinal diseases. Current evidence indicates a strong bidirectional interaction between microbiome perturbation and immune dysregulation. The aim of this Research Topic is to create a platform for the advancement of research on the causal relationship between the microbiome and immunity. Besides, we would like to define the core microbiota responsible for the initiation and progression of intestinal diseases, the molecular mechanisms of host immune-microbiome interactions, and novel gut-targeted pharmacological interventions to achieve a positive impact on intestinal disease.

The Human Microbiome, Diet, and Health

The Human Microbiome, Diet, and Health PDF Author: Food Forum
Publisher: National Academies Press
ISBN: 030926586X
Category : Medical
Languages : en
Pages : 197

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Book Description
The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.

Janeway's Immunobiology

Janeway's Immunobiology PDF Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :

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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Immunobiotics: Interactions of Beneficial Microbes with the Immune System

Immunobiotics: Interactions of Beneficial Microbes with the Immune System PDF Author: Julio Villena
Publisher: Frontiers Media SA
ISBN: 2889453820
Category :
Languages : en
Pages : 309

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Book Description
The term “immunobiotics” has been proposed to define microbial strains able to beneficially regulate the mucosal immune system. Research in immunobiotics has significantly evolved as researchers employed cutting-edge technologies to investigate the complex interactions of these beneficial microorganisms with the immune system. During the last decade, our understanding of immunobiotics-host interaction was profoundly transformed by the discovery of microbial molecules and host receptors involved in the modulation of gut associated immune system, as well as the systemic and distant mucosal immune systems. In recent years, there has been a substantial increase in the number of reports describing the beneficial effects of immunobiotics in diseases such as intestinal and respiratory infections, allergy, inflammatory bowel disease, obesity, immunosuppression, and several other immune-mediated conditions. Evidence is also emerging of immunobiotics related molecules with immunomodulatory functions leading to the production of pharmabiotics, which may positively influence human or animal health. Therefore, research in immunobiotics continue to contribute not only to food but also medical and pharmaceutical fields. The compilation of research articles included in this ebook should help reader to have an overview of the recent advances in immunobiotics.

The Chemistry of Microbiomes

The Chemistry of Microbiomes PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309458390
Category : Science
Languages : en
Pages : 133

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Book Description
The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.

Adult Short Bowel Syndrome

Adult Short Bowel Syndrome PDF Author: Mandy L. Corrigan
Publisher: Academic Press
ISBN: 0128143312
Category : Technology & Engineering
Languages : en
Pages : 255

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Book Description
Adult Short Bowel Syndrome: Nutritional, Medical, and Surgical Management serves as a practical guide to the medical, surgical and nutritional care of complex patients with Short Bowel Syndrome (SBS), providing information on SBS with the most up-to-date, evidence-based data available. Additionally, the book presents global perspectives and highlights emerging areas of research that are influencing the care of patients with SBS. Intended for nutritionists, dieticians, physicians (specifically, general practitioners, gastroenterologists, and surgeons), nurse practitioners, pharmacists, students and researchers, this book serves as a quick reference on the medical, surgical and nutritional care of complex patients with short bowel syndrome. - Presents emerging areas of research related to Short Bowel Syndrome (gut microbiome, pre/probiotics), as well as current applications in clinical practice - Compiles an overview, classification and complications of the Short Bowel Syndrome disease state - Contains effective dietary concepts (including rationale and use of oral rehydration solutions) for managing malabsorption caused by Short Bowel Syndrome - Includes medical and pharmaceutical management techniques to compliment nutrition interventions - Discusses surgical options for consideration in patients with Short Bowel Syndrome - Highlights international perspectives on treatment and care

Probiotics and Prebiotics

Probiotics and Prebiotics PDF Author: Koen Venema
Publisher: Caister Academic Press Limited
ISBN: 9781910190098
Category : Medical
Languages : en
Pages : 0

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Book Description
Composed of nearly a thousand different types of microorganisms - some beneficial, others not - the human gut microbiota plays an important role in health and disease. This is due to the presence of probiotic or beneficial microbes, or due to the feeding of prebiotics that stimulate the endogenous beneficial microbes (these promote health by stimulating the immune system, improving the digestion and absorption of nutrients, and inhibiting the growth of pathogens). The notable health benefits of probiotic organisms have prompted much commercial interest, which in turn has led to a plethora of research initiatives in this area. These range from studies to elucidate the efficacy of the various health benefits to analyses of the diet-microbe interaction as a means of modulating the gut microbiota composition. Research in this area is at a very exciting stage. With state-of-the-art commentaries on all aspects of probiotics and prebiotics research, this book provides an authoritative and timely overview of the field. Written by leading international researchers, each chapter affords critical insight to a particular topic, reviews current research, discusses future direction, and stimulates discussion. Topics range from the different microorganisms used as probiotics (lactobacilli, bifidobacteria, yeast, etc.), and the techniques and approaches used (metagenomics, etc.), to the reviews of the clinical and medical aspects. The provision of extensive reference sections positively encourages readers to pursue each subject in greater detail. *** Librarians: ebook available on ProQuest and EBSCO [Subject: Microbiology, Life Science]