Inflammatory Bowel Diseases: New Insights Into Mechanisms of Inflammation and Challenges in Diagnosis and Treatment

Inflammatory Bowel Diseases: New Insights Into Mechanisms of Inflammation and Challenges in Diagnosis and Treatment PDF Author: E. Monteiro
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 376

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Book Description
This volume contains the proceedings of Falk Symposium No. 76, held in Estoril, Portugal, May 5--7, 1994, and presents a modern aetiopathogenesis-based approach to clinical, diagnostic and therapeutic developments in inflammatory bowel disease. The first section deals with the first results of a prospective epidemiological study in the EEC countries, while subsequent sections cover the most important factors responsible for IBD, diagnosis, controversies in clinical management, new insights into therapy, and difficult clinical problems. The book closes with a state-of-the-art overview of the new knowledge as well as future perspectives regarding diagnosis and treatment. It will be of interest to all clinicians and researchers in this important area of gastroenterology.

Inflammatory Bowel Diseases: New Insights Into Mechanisms of Inflammation and Challenges in Diagnosis and Treatment

Inflammatory Bowel Diseases: New Insights Into Mechanisms of Inflammation and Challenges in Diagnosis and Treatment PDF Author: E. Monteiro
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 376

Get Book Here

Book Description
This volume contains the proceedings of Falk Symposium No. 76, held in Estoril, Portugal, May 5--7, 1994, and presents a modern aetiopathogenesis-based approach to clinical, diagnostic and therapeutic developments in inflammatory bowel disease. The first section deals with the first results of a prospective epidemiological study in the EEC countries, while subsequent sections cover the most important factors responsible for IBD, diagnosis, controversies in clinical management, new insights into therapy, and difficult clinical problems. The book closes with a state-of-the-art overview of the new knowledge as well as future perspectives regarding diagnosis and treatment. It will be of interest to all clinicians and researchers in this important area of gastroenterology.

Pediatric Inflammatory Bowel Disease

Pediatric Inflammatory Bowel Disease PDF Author: Petar Mamula
Publisher: Springer Science & Business Media
ISBN: 1461450616
Category : Medical
Languages : en
Pages : 573

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Book Description
Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figures to improve readability and make for an efficient reference for clinicians to use. Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists.

Enteric Glia

Enteric Glia PDF Author: Brian D. Gulbransen
Publisher: Biota Publishing
ISBN: 1615046615
Category : Medical
Languages : en
Pages : 72

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Book Description
The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography

VI International Symposium on Inflammatory Bowel Diseases

VI International Symposium on Inflammatory Bowel Diseases PDF Author: D. Rachmilewitz
Publisher: Springer Science & Business Media
ISBN: 9780792387732
Category : Medical
Languages : en
Pages : 266

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Book Description
This book, the proceedings of Falk Symposium No. 123, VI International Symposium on Inflammatory Bowel Diseases, held in Istanbul, Turkey, on September 3-5, 2001, focuses on the issues and controversies pertinent to IBD in the 21st century. The achievements in medical, surgical, and in the basic sciences in the last twenty years since the first Jerusalem IBD Symposium are summarized in detail. Controversies with respect to the medical treatment of inflammatory bowel diseases are discussed. One section deals with surgical issues such as laparoscopic surgery in inflammatory bowel diseases, ileo-anal pouches and the surgical treatment of Crohn's disease. The last section is devoted to the biological treatment of IBD and to the needs both in medical science and in the clinic.

Mechanisms of Intestinal Inflammation

Mechanisms of Intestinal Inflammation PDF Author: R. Duchmann
Publisher: Springer Science & Business Media
ISBN: 9780792387879
Category : Medical
Languages : en
Pages : 246

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Book Description
In recent years considerable progress has been achieved in regard to our understanding of the induction and modulation of the immune response in the intestinal mucosa. It is clear that this mucosal immune reaction is predominantly steered by certain T-cell populations, which are characterized by their cytokine secretion profile. Less well known are the conditions under which the uptake and processing of a specific antigen leads to a certain immune response, whether it be protective, tolerant or inflammatory. However, here again distinct progress has been made in our understanding. Equally significant for immune regulation in the gut appears to be so-called innate immunity. Every shift of equilibrium in the highly regulated mucosal immune reaction is accompanied by an inflammatory reaction and destruction of the mucosa. In nearly all cases, this inflammatory response is dependent on the presence of bacterial intestinal flora. This book, the proceedings of Falk Symposium 133 on Mechanisms of Intestinal Inflammation: Implications for Therapeutic Intervention in IBD', held in Berlin, Germany, on 10-11 June 2003, summarizes present knowledge in the area of unspecific and specific immune reactions in the gut, recording the gaps in our knowledge and, in particular, presenting the possibilities of targeted intervention. The link to inflammatory bowel diseases - Crohn's disease and ulcerative colitis - is always in focus. Chapters by an international panel of basic scientists, clinical researchers and clinicians also record the problems which can originate through today's possible modulation of the immune reaction, setting the basis for review of clinical problems. This book is valuable readings for all scientists and physicians, who, from different perspectives, have an interest in research on IBD and in the clinical management of these diseases.

Advances in Inflammatory Bowel Diseases

Advances in Inflammatory Bowel Diseases PDF Author: P. Rutgeerts
Publisher: Springer Science & Business Media
ISBN: 9780792387503
Category : Medical
Languages : en
Pages : 340

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Book Description
Ulcerative colitis and Crohn's disease remain a great therapeutic challenge to the medical community. In recent years knowledge about the pathogenesis of these diseases has progressed rapidly but the cause of the diseases remains completely unknown. It has become clear that dysregulation of the mucosal immune system is the basis for the chronic evolution of the diseases in a genetically susceptible population. Exciting new therapeutic approaches have been attempted in the last couple of years and cytokine and anti-cytokine treatments in particular seem very promising, especially in intractable disease. The format of the Falk Symposium 106 on `Advances in Inflammatory Bowel Diseases', held in Brussels, Belgium, June 18-20, 1998, was somewhat innovative as each session attempted to link the new insights into pathogenetic mechanisms with new therapeutic approaches, resulting in optimal information transfer. The classic therapeutic schemes were updated with a special focus on step-wise build-up of therapy.

Inflammatory Bowel Diseases

Inflammatory Bowel Diseases PDF Author: G.N. Tytgat
Publisher: Springer Science & Business Media
ISBN: 9780792388944
Category : Medical
Languages : en
Pages : 746

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Book Description
There is currently an explosive growth of basic and clinical research in inflammatory bowel diseases. The extensive interest of the medical community in these diseases is largely explained by the devastating impact the illnesses have on the quality of life, their high prevalence in the community, and the fact that so many medical disciplines are involved in tackling the immensely complex studies on pathogenesis, clinical expression and treatment possibilities. The Falk Symposium No. 85 held in The Hague, the Netherlands, 29 June-1 July 1995 brought together over 80 speakers and 1000 participants from all over the world. Plenary sessions and workshops allowed the discussion of basic and clinical research, enabling appropriate choices to be made. Topics reflected areas of high current basic research interest, clinical importance, and actual or future treatment potential. Audience: An important work for all disciplines involved in research and therapy of inflammatory bowel diseases.

Intestinal Mucosa and Its Diseases - Pathophysiology and Clinics

Intestinal Mucosa and Its Diseases - Pathophysiology and Clinics PDF Author: W. Domschke
Publisher: Springer Science & Business Media
ISBN: 9780792387541
Category : Medical
Languages : en
Pages : 542

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Book Description
These proceedings of Falk Symposium 110 on `Intestinal Mucosa and its Diseases - Pathophysiology and Clinics' held at Titisee/Black Forest, Germany, 16-17 October 1998, comprehensively review salient clinical as well as scientific aspects - pending or settled - of the main intestinal diseases. In particular, chapters deal with infectious and neuroendocrine diarrhoeas, coeliac sprue, allergic enteropathy, intestinal lymphomas, colorectal carcinomas, and chronic inflammatory bowel diseases, in terms of clinical presentation as well as underlying mechanisms. This book therefore aims to bridge the gaps between basic science and clinics for the eventual treatment of patients afflicted with these diseases.

Inflammatory Bowel Disease: Translation from Basic Research to Clinical Practice

Inflammatory Bowel Disease: Translation from Basic Research to Clinical Practice PDF Author: B. Vucelic
Publisher: Springer Science & Business Media
ISBN: 9781402028472
Category : Medical
Languages : en
Pages : 314

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Book Description
The amount of information on the pathogenesis of inflammatory bowel disease is growing rapidly. This is reflected by a continuous increase in the number of papers presented at international GI meetings. To make things more difficult for practicing physicians, there is also a large number of new clinical trials being published which require periodical critical reviews and recommendations. Faced with these issues, the scientific commitee of the Falk Symposium No. 140 decided to take a different approach and to apply a novel format that is reflected in the title of the Symposium: "Translation from basic research to clinical practice". This book contains the proceedings of that Symposium, held in Dubrovnik, Croatia, on May 7–8, 2004. The sections are designed so that they start with the information from basic sciences on different aspects of these complex diseases and further lead to their clinical implications. Special attention is paid to the mechanisms of actions of established drugs. The last two sections are clinically oriented and focus on the most difficult aspects of both Crohn's disease and ulcerative colitis. This format provides state-of-the-art chapters by leading experts in the field and at the same time up-to-date information on the clinical application of the new knowledge.

Induction and Modulation of Gastrointestinal Inflammation

Induction and Modulation of Gastrointestinal Inflammation PDF Author: A. Stallmach
Publisher: Springer Science & Business Media
ISBN: 9780792387473
Category : Medical
Languages : en
Pages : 350

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Book Description
This book, the proceedings of Falk Symposium No. 104, organized in collaboration with the Society of Mucosal Immunology, and held in Saarbrucken, Germany, March 5-7 1998, is centered around the immunological mechanisms of mucosal protection and their disturbances leading to intestinal inflammation and destruction. This is a rapidly expanding field involving recent knowledge of basic immunology and cell biology as well as clinical observations. The conference and this book summarize very recent data in this field and suggest strategies for future research and clinical applications, and will be of interest to both basic scientists and clinicians.