Inflammation and Stroke PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Inflammation and Stroke PDF full book. Access full book title Inflammation and Stroke by Giora Z. Feuerstein. Download full books in PDF and EPUB format.
Author: Giora Z. Feuerstein
Publisher: Springer
ISBN: 3034882971
Category : Medical
Languages : en
Pages : 351
Get Book
Book Description
Stroke is a leading cause of death in developed countries. However, current therapeutic strategies for stroke have been largely unsuccessful. One possible explanation is that research and pharmacological management have focused on very early events in brain ischemia. New research has shown that brain ischemia and trauma elicit strong inflammatory reactions driven by both external and brain cells. The recognition of inflammation as a fundamental response to brain ischemia provides novel opportunities for new anti-inflammatory therapies. For the first time, an international body of researchers presents the latest findings about the cellular and humoral aspects of immune and inflammatory reactions in the brain. The work may have an impact on the treatment of neuroinjuries and ancillary brain diseases, and increase the understanding of the roles infections and immune reactions play in the brain milieu.
Author: Giora Z. Feuerstein
Publisher: Springer
ISBN: 3034882971
Category : Medical
Languages : en
Pages : 351
Get Book
Book Description
Stroke is a leading cause of death in developed countries. However, current therapeutic strategies for stroke have been largely unsuccessful. One possible explanation is that research and pharmacological management have focused on very early events in brain ischemia. New research has shown that brain ischemia and trauma elicit strong inflammatory reactions driven by both external and brain cells. The recognition of inflammation as a fundamental response to brain ischemia provides novel opportunities for new anti-inflammatory therapies. For the first time, an international body of researchers presents the latest findings about the cellular and humoral aspects of immune and inflammatory reactions in the brain. The work may have an impact on the treatment of neuroinjuries and ancillary brain diseases, and increase the understanding of the roles infections and immune reactions play in the brain milieu.
Author: Ulrich Dirnagl
Publisher: Springer Science & Business Media
ISBN: 3662054264
Category : Medical
Languages : en
Pages : 248
Get Book
Book Description
The successful treatment of acute stroke remains one of the major challenges in clinical medicine. Over the last decades, the understanding of stroke pathophysiology has greatly improved, while the therapeutic options in stroke therapy remain very limited. Today, hyperacute mechanisms of damage, such as excitotoxicity, can be discriminated from delayed ones, such as inflammation and apoptosis. Targeting of inflammation has already been successfully applied in various stroke models, but translation into a clinically efficacious strategy has not been achieved so far. In this book, leading experts in basic cerebrovascular research as well as stroke treatment review the current evidence for and against an important role for inflammation in stroke, and explore the potential of treating or modulating inflammation in stroke therapy.
Author: Giora Z. Feuerstein
Publisher: Birkhauser Basel
ISBN: 9783764365110
Category : Medical
Languages : en
Pages : 356
Get Book
Book Description
Stroke is a leading cause of death in developed countries. However, current therapeutic strategies for stroke have been largely unsuccessful. One possible explanation is that research and pharmacological management have focused on very early events in brain ischemia. New research has shown that brain ischemia and trauma elicit strong inflammatory reactions driven by both external and brain cells. The recognition of inflammation as a fundamental response to brain ischemia provides novel opportunities for new anti-inflammatory therapies. For the first time, an international body of researchers presents the latest findings about the cellular and humoral aspects of immune and inflammatory reactions in the brain. The work may have an impact on the treatment of neuroinjuries and ancillary brain diseases, and increase the understanding of the roles infections and immune reactions play in the brain milieu.
Author: Michael Brainin
Publisher: Cambridge University Press
ISBN: 1107047498
Category : Medical
Languages : en
Pages : 425
Get Book
Book Description
Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.
Author: E. Steve Roach
Publisher: Cambridge University Press
ISBN: 1139855581
Category : Medical
Languages : en
Pages : 445
Get Book
Book Description
Toole's Cerebrovascular Disorders was the first modern book devoted to care of the stroke, originally published more than 40 years ago. This is a completely revised and updated sixth edition of the highly respected standard for stroke diagnosis and treatment. Dr James Toole has stayed on as a consultant for the text, and Drs E. Steve Roach, Kerstin Bettermann, and Jose Biller have reworked Dr Toole's book to include chapters on genetics, pregnancy-related stroke, and acute treatments. The practical focus of the book has not changed, retaining its emphasis on bedside diagnosis and treatment. Easily accessible both for stroke specialists and residents, the sixth edition has been modernized to keep pace with the rapid expansion of knowledge in stroke care and includes evidence-based recommendations, the latest technology and imaging, and risk factors. The text is supplemented with more than 200 images, many in color.
Author: Ranjana Patnaik
Publisher: Springer
ISBN: 9789811314520
Category : Medical
Languages : en
Pages : 0
Get Book
Book Description
This book provides detailed and comprehensive mechanistic insights of the various risk factors that lead to the ischemic stroke and the novel therapeutic interventions against it. The first section discusses the different ischemic cerebral stroke-induced inflammatory pathways and dysfunctionality of blood-brain barrier. The later sections of the book deals with the role of endoplasmic reticulum stress and mitophagy in cerebral stroke and introduces the different neuroimaging techniques such as Computed tomography (CT), Magnetic resonance imaging (MRI), Positron emission tomography (PET) and Single-Photon emission computed tomography (SPECT) that are used to identify the arterial blockages. The final section comprises of chapters that focus on various neuroprotective strategies and emerging therapeutic interventions for combating stroke pathophysiology. The chapters cover the role of stem cell therapy, the therapeutic effect of low-frequency electromagnetic radiations (LF-EMR), and implications of non-coding RNAs such as micro-RNAs as the biomarkers for diagnosis, prognosis, and therapy in ischemic stroke.
Author: Julien Bogousslavsky
Publisher: Cambridge University Press
ISBN: 9780521771450
Category : Medical
Languages : en
Pages : 418
Get Book
Book Description
An essential resource for diagnosis and treatment of stroke patients outside the usual clinical categories.
Author: Christian Wilde
Publisher:
ISBN: 9780972495905
Category : Health & Fitness
Languages : en
Pages : 0
Get Book
Book Description
Written to empower you to interface intelligently with your doctors in protecting yourself and your family from America's number one killer. Written in everyday language, this book prepares you to discuss the cutting edge blood tests for C-reactive protein, inherited and acquired hidden risk factors and how to neutralize them by natural means. Rarely has a book drawn such enthusiastic endorsements from leaders in cardiology, even recommended for doctors. HEA000000
Author: Mario Di Napoli
Publisher:
ISBN: 9781606920305
Category : Cerebral ischemia
Languages : en
Pages : 0
Get Book
Book Description
Ischemic stroke is a devastating clinical event. Increasing evidence suggests that inflammatory mechanisms are involved in the progression of post ischemic-induced brain injury. Cerebral ischemia is accompanied by a marked inflammatory reaction that is initiated by ischemia-induced expression of cytokines, adhesion molecules, and other inflammatory mediators, including prostanoids, extracellular proteases, reactive oxygen species and nitric oxide, leading to the accumulation of inflammatory cells, such as leukocytes and microglia. The inflammatory reaction, which has a rapid onset and continues after the stroke, is thought to acutely contribute to the evolution of tissue injury. Many compounds have been identified in cerebral ischemia, which are known to promote and sustain inflammatory responses. Better understanding of the role of the post ischemic-induced inflammatory response and its potential for modulation might have profound implications for patient treatment. Pre-clinical studies suggest that interventions that are aimed at attenuating such inflammation reduce the progression of brain damage that occurs during the late stages of cerebral ischemia. In particular, strategies that block the activity of inflammation-related enzymes reduce ischemic damage with an extended therapeutic window. In this review, a summary of the available literature on the inflammatory responses after cerebral ischemia and ischemic stroke is presented along with discussion of some of the emerging opportunities for potential therapeutic strategies. Although at the moment, clinical trials using anti-inflammatory strategies did not show benefit in patients with ischemic stroke, there is a strong rationale for continuing to explore the efficacy of anti-inflammatory therapies in the treatment of the late stages of cerebral ischemia. It is plausible that in the near future, additional strategies using neuroprotective drug cocktails that target inflammation could offer exciting new promise in the therapeutic approach to ischemic stroke.
Author: Michel T. Torbey
Publisher: Cambridge University Press
ISBN: 1107634725
Category : Medical
Languages : en
Pages : 395
Get Book
Book Description
An essential companion for busy professionals seeking to navigate stroke-related clinical situations successfully and make quick informed treatment decisions.
