Immune response to SARS-CoV-2 and implications for clinical outcome

Immune response to SARS-CoV-2 and implications for clinical outcome PDF Author: Edwin Bölke
Publisher: Frontiers Media SA
ISBN: 2832530737
Category : Medical
Languages : en
Pages : 412

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Book Description

Immune response to SARS-CoV-2 and implications for clinical outcome

Immune response to SARS-CoV-2 and implications for clinical outcome PDF Author: Edwin Bölke
Publisher: Frontiers Media SA
ISBN: 2832530737
Category : Medical
Languages : en
Pages : 412

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Book Description


Naturally Occurring Antibodies (NAbs)

Naturally Occurring Antibodies (NAbs) PDF Author: Hans U. Lutz
Publisher: Springer Science & Business Media
ISBN: 1461434610
Category : Medical
Languages : en
Pages : 285

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Book Description
This volume illustrates the functional properties of NAbs. Authors from pioneering groups report in their chapters on the tissue homeostatic, tissue regenerating and regulatory properties of NAbs and NAbs in pooled human IgG. Scientists interested in the regulation and modulation of components of the immune system found a whole variety of NAbs to cytokines with regulatory and protective functions and NAbs that modulate, e.g., dendritic cells, regulatory T cells, B cells and granulocytes. Considering the large plasma pools and initial difficulties in preparing IVIG that does not induce adverse effects upon infusion into recipients, this volume ends with a historical chapter on how pooled human plasma was fractionated and the IgG component pretreated for a safe intravenous application.

National Institute of Allergy and Infectious Diseases, NIH

National Institute of Allergy and Infectious Diseases, NIH PDF Author: Vassil St. Georgiev
Publisher: Springer Science & Business Media
ISBN: 1597455695
Category : Medical
Languages : en
Pages : 537

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Book Description
For over 50 years, the mission of the National Institute of Allergy and Infectious Diseases (NIAID) has been to conduct and support basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases with the ultimate goal of improving the health of individuals in the United States and around the world. As part of its mission to foster biomedical discovery and to reduce the burden of human disease, NIAID is committed to encouraging the accelerated translation of biomedical discoveries into effective clinical care and public health practice throughout the world. In pursuit of this goal and its disease-specific scientific objectives, NIAID seeks to broaden research opportunities and collaborations involving scientists and institutions outside the United States. National Institute of Allergy and Infectious Diseases, NIH: Volume 1, Frontiers in Research contains presentations given at the 2006 NIAID Research Conference held in Opatija, Croatia which brought internationally known researchers from the United States and Central and Eastern Europe to focus together on shared interests in microbiology, infectious disease, HIV/AIDS, and basic and clinical immunology. Some of the topics covered include emerging and re-emerging infections, the development of infectious disease prophylactics and therapeutics, drug resistance, and various topics in immunomodulation, autoimmunity, infections and immunity, and the development of vaccines. Extensive and in-depth, National Institute of Allergy and Infectious Diseases, NIH: Volume 1, Frontiers in Research is a valuable, comprehensive guide to the state of research today.

Structural Immunology

Structural Immunology PDF Author: Tengchuan Jin
Publisher: Springer Nature
ISBN: 9811393672
Category : Medical
Languages : en
Pages : 234

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Book Description
This book presents a comprehensive overview of important immune molecules and their structure-function relationships. The immune system is highly complex, consisting of a network of molecules, cells, tissues and organs, and the immune reaction is involved in various physiological as well as pathological processes, including development, self-tolerance, infection, immunity, and cancer. Numerous molecules participate in immune recognition, inhibition and activation, and these important immune molecules can be roughly divided into cell surface receptors, intracellular receptors and intracellular signaling molecules. The study of how these immune molecules function at molecular level has laid the foundation for understanding the immune system. The book provides researchers and students with the latest research advances concerning the structural biology of key immune molecules/pathways, and offers immunologists essential insights into how these immune molecules function.

Diagnostic Procedures for Viral, Rickettsial, and Chlamydial Infections

Diagnostic Procedures for Viral, Rickettsial, and Chlamydial Infections PDF Author: Edwin H. Lennette
Publisher:
ISBN: 9780875532202
Category : Chlamydia infections
Languages : en
Pages : 0

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Book Description


Immunoepidemiology

Immunoepidemiology PDF Author: Peter J. Krause
Publisher: Springer Nature
ISBN: 3030255530
Category : Medical
Languages : en
Pages : 306

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Book Description
This textbook focuses on the nascent field of Immunoepidemiology that addresses how differences in immune responses among individuals affect the epidemiology of infectious diseases, cancer, hypersensitivity, and autoimmunity. The idea for the book originated from a course entitled “Immunology for Epidemiologists“ at the Yale School of Public Health. While many fine textbooks are available that address the immunological responses of individuals to pathogens, these provided very little information regarding how immunological variation among populations affects the epidemiology of disease. And yet, it has long been recognized that there is great immunologic diversity among people, which can have a profound effect on the epidemiology of disease. Careful review of the immunologic and epidemiologic literature revealed that there have been relatively few publications concerning immunoepidemiology and that no textbook is available on the subject. This textbook therefore aims to fill this void by providing a much-needed tool to comprehensively and efficiently teach immunoepidemiology. The book includes a section on the basic principles of immunology, and then applies them to particular examples of disease in human populations. The target audience for this text book are Masters of Public Health students. Others who should also find it of interest include PhD students in epidemiology, immunology, medical students, generalists, and specialists in immunology, infectious diseases, cancer, and rheumatology.

The Inflammasome

The Inflammasome PDF Author: Christine M. De Nardo
Publisher: Humana
ISBN: 9781627035224
Category : Medical
Languages : en
Pages : 0

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Book Description
This Methods in Molecular Biology book offers methods for studying inflammasome function, including generation of inflammasome stimuli, monitoring of caspase-1 activity and processing, activation of IL-1β cytokines, plus lab protocols, material lists and tips.

Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2

Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2 PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309680948
Category : Medical
Languages : en
Pages : 111

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Book Description
In December 2019, new cases of severe pneumonia were first detected in Wuhan, China, and the cause was determined to be a novel beta coronavirus related to the severe acute respiratory syndrome (SARS) coronavirus that emerged from a bat reservoir in 2002. Within six months, this new virusâ€"SARS coronavirus 2 (SARS-CoV-2)â€"has spread worldwide, infecting at least 10 million people with an estimated 500,000 deaths. COVID-19, the disease caused by SARS-CoV-2, was declared a public health emergency of international concern on January 30, 2020 by the World Health Organization (WHO) and a pandemic on March 11, 2020. To date, there is no approved effective treatment or vaccine for COVID-19, and it continues to spread in many countries. Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2: Modernizing Pandemic Response Strategies lays out a framework to define and describe the data needs for a system to track and correlate viral genome sequences with clinical and epidemiological data. Such a system would help ensure the integration of data on viral evolution with detection, diagnostic, and countermeasure efforts. This report also explores data collection mechanisms to ensure a representative global sample set of all relevant extant sequences and considers challenges and opportunities for coordination across existing domestic, global, and regional data sources.

World Health Statistics 2009

World Health Statistics 2009 PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241563818
Category : Communicable diseases
Languages : en
Pages : 150

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Book Description
World Health Statistics 2009 contains WHO's annual compilation of data from its 193 member states, and includes a summary of progress towards the health-related millennium development goals and targets. This edition also contains a new section on reported cases of selected infectious diseases. It provides a comprehensive summary of the current status of national health and health systems including; mortality and burden of disease, causes of death, reported infectious diseases, health service coverage, risk factors, health systems resources, health expenditures, inequities and demographic and socioeconomic statistics. The section on inequities presents statistics on the distribution of selected health outcomes and interventions within countries, disaggregated by sex, age, urban and rural settings, wealth, and educational level. WHO presents World Health Statistics 2009 as an integral part of its ongoing effort to inform better measures of population health and national health systems.

Pediatric Critical Care Study Guide

Pediatric Critical Care Study Guide PDF Author: Steven E. Lucking
Publisher: Springer Science & Business Media
ISBN: 0857299239
Category : Medical
Languages : en
Pages : 971

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Book Description
This is the first comprehensive study guide covering all aspects of pediatric critical care medicine. It fills a void that exists in learning resources currently available to pediatric critical care practitioners. The major textbooks are excellent references, but do not allow concise reading on specific topics and are not intended to act as both text and study guide. There are also several handbooks available, but these are usually written for general pediatric residents and lack the advanced physiology and pathophysiology required for the higher level pediatric critical care practitioner