Author: Walter K.H. Krause
Publisher: Springer
ISBN: 3319407880
Category : Health & Fitness
Languages : en
Pages : 297

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Book Description
This book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.

Author: John A.H. Wass
Publisher: Oxford University Press, USA
ISBN: 0199235295
Category : Medical
Languages : en
Pages : 2158

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Book Description
Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.

Author: Walter K.H. Krause
Publisher: Springer Science & Business Media
ISBN: 3642013791
Category : Health & Fitness
Languages : en
Pages : 233

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Book Description
Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the female partner. Immune reactions to sperm can contribute up to 2–30% of infertility. The sperm has both autoantigenic as well as isoantigenic potential, and is thus capable of p- ducing antisperm antibodies (ASAs) and sperm-reactive T cells in both infertile men and women. Also, over 75% vasectomized men produce autoantibodies to sperm that can cause a problem in regaining fertility even after successful re-anastomosis in vasovasostomy. Early claims regarding the incidence and involvement of ASAs in involuntary human infertility were probably overemphasized because of unreliable techniques and naivety concerning the complexity of the immune response and antigenic nature of the sperm cell. These factors, the lack of well-designed and controlled experimental studies, and the dearth of effective therapeutic modalities resulted in the confusion of the occurrence and importance of ASAs in human infertility. Consequently, evaluation of infertile couples for ASAs and their possible role in infertility was not considered a signifcant proposition. The development of more accurate assays and the discovery of mucosal immunity capable of responses independent of systemic immunity have caused inclusion of sperm cells and genital tract secretions in the analysis of ASAs.

Author: Larry I. Lipshultz
Publisher: Cambridge University Press
ISBN: 1139483242
Category : Medical
Languages : en
Pages : 691

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Book Description
The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.

Author: R.F. Harrison
Publisher: Springer Science & Business Media
ISBN: 9401176213
Category : Medical
Languages : en
Pages : 230

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Book Description
This is the second compilation of papers given during the Related Communica tions Sessions of the XIth International Federation of Fertility Societies World Congress held on June 26th-July 1st 1983 at the Royal Dublin Society, Dublin, Ireland. Except for Part I, where results of animal experimentations are gathered together, the volume is concerned solely with studies in the human. The role of infection and endometriosis in the aetiology and treatment of the tubo uteroperitoneal factor in infertility are the concern of Parts II and III. Diagnostic and therapeutic aspects of tubal disease are covered in Parts IV and V and the book ends with Part VI, chapters on the uterus and vagina. Laparoscopy and microsurgical techniques have undoubtedly transformed the diagnostic and therapeutic outlook in this area of infertility. This book shows you how far such techniques have progressed and how much there is yet to do. Dublin, 1983 Robert F. Harrison lohnBonnar William Thompson xi List of Contributors 5. A.Z. BADAWY J. ABE Department of Obstetrics and Gynecology Department of Obstetrics and Gynecology Kyoto Prefectural University of Medicine Upstate Medical Center Kawarmachi-Hirokogi, Kamikyoku, Kyoto 750 E. Adams Street JAPAN 602 Syracuse, NY 13210 USA M. ALACHMAR "Marika Eliadi" Maternity Hospital 2 Helena Venizelos Square M. BERG Athens 115 21 Department of Clinical Sciences GREECE University of Tampere Teiskontie 35 W. ALBRICH SF-33520 Tampere Department of Obstetrics and Gynecology FINLAND University of Munich Marchioninistrasse D-8000 Munich 70 G.

Author: Jane Lyttleton
Publisher: Elsevier Health Sciences
ISBN: 0702054321
Category : Medical
Languages : en
Pages : 517

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Book Description
The second edition of this popular text systematically addresses all aspects of treatment of infertility using Chinese medicine. Clinically focused and with a new easy-to-navigate design, the book begins by covering all the essential fundamentals you will need to understand and treat infertility, before going on to look at what Chinese medicine offers in the way of treatment for functional infertility in men and women, gynecological disorders which contribute to infertility and relevant lifestyle factors. Jane Lyttleton importantly devotes a large part of the book to discussing ways in which Chinese medicine and Western medicine might work together to overcome infertility, and details the increased experience over the past decade in working with IVF patients and their specialists. Leaps forward have also been made in the understanding of conditions such as Polycystic ovarian syndrome and immune infertility. New Features · Greatly expanded section on the place of Chinese medicine and IVF in treatment of infertility · New information on Polycystic ovarian disease and immune infertility and how Chinese medicine approaches their treatment · Updated and balanced advice on pre-conception care · Clinically focused, with easy-to-navigate design

Author: Glenn L. Schattman
Publisher: Springer
ISBN: 1493921401
Category : Health & Fitness
Languages : en
Pages : 348

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Book Description
Written and edited by leading, internationally recognized clinicians and scientists in reproductive medicine and related fields, this unique text is a practical and comprehensive review of the clinical and scientific significance of unexplained male and female infertility and its management. The book is divided into thematic sections to ensure the most useful presentation of topics, opening with definitions and epidemiology of unexplained infertility, including discussion of the WHO’s cutoff values for human semen characteristics and its ramifications. Sections covering male and female reproductive pathophysiology follow respectively, covering biological, genetic and environmental causative factors, with a subsequent section on evaluative techniques for male and female patients. Expectant, medical and surgical treatment strategies comprise the fifth section of the book, where active interventions and outcomes of each treatment modality are carefully considered. The final section discusses assisted reproductive techniques to manage unexplained infertility, such as intrauterine insemination and in vitro fertilization, as well as future perspectives. Thoughtful and enlightening, Unexplained Infertility: Pathophysiology, Evaluation and Treatment will be an invaluable resource for all clinicians and scientists working in the fields of reproductive medicine and infertility.

Author: Ernst Rainer Weissenbacher
Publisher: Springer Science & Business Media
ISBN: 3642149065
Category : Medical
Languages : en
Pages : 268

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Book Description
This book systematically reviews and discusses recent studies and articles on the immunology of female genital tract tissue. The scope is broad, encompassing innate immune responses, adaptive (humoral and cell-mediated) immunity, the immunology of menstruation, the immunology of viral and bacterial infections, the immunology of normal and abnormal pregnancy, and immunological infertility. Throughout, tables and illustrations are judiciously used to facilitate understanding. Immunology of the Female Genital Tract will serve as an invaluable source of up-to-date information for all with an interest in this subject.

Author: Alan E. Beer
Publisher: AJR Publishing
ISBN: 9780978507800
Category : Fertility, Human
Languages : en
Pages : 0

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Book Description
According to this reference from a leading authority who has worked with more than 7,000 couples, women who have experienced difficulty conceiving or multiple miscarriages may be suffering from treatable dysfunctions of their immune systems.

Author: P.H. Vogt
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318060984
Category : Medical
Languages : en
Pages : 190

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Book Description
Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.