Imaging Biomarkers in Epilepsy PDF Download
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Author: Andrea Bernasconi
Publisher: Cambridge University Press
ISBN: 1107108357
Category : Medical
Languages : en
Pages : 263
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Book Description
Assembles world-class expertise on clinical and molecular imaging-derived biomarkers, presenting neuroimaging in epilepsy in a broad neuroscientific context.
Author: Andrea Bernasconi
Publisher: Cambridge University Press
ISBN: 1107108357
Category : Medical
Languages : en
Pages : 263
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Book Description
Assembles world-class expertise on clinical and molecular imaging-derived biomarkers, presenting neuroimaging in epilepsy in a broad neuroscientific context.
Author: Harry Chugani, MD
Publisher: Oxford University Press
ISBN: 0199711526
Category : Medical
Languages : en
Pages :
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Book Description
Perhaps the most important achievements in the field of epileptology in the past two decades have been in the neuroimaging and genetic breakthroughs as applied to patients with epilepsy. Indeed, neuroimaging has become a vital part in the study of epilepsy, affecting broad aspects of the disorder ranging from diagnosis and classification to treatment and prognosis. Neuroimaging in epilepsy encompasses many different approaches that have reached various levels of expertise across epilepsy centers worldwide. This book discusses every imaging modality used to gather information on epilepsy. Each technique is described by world experts and epilepsy centers worldwide.
Author: Jerome Engel Jr
Publisher: Oxford University Press
ISBN: 019532854X
Category : Medical
Languages : en
Pages : 737
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Book Description
This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.
Author: Andrea Bernasconi
Publisher: Cambridge University Press
ISBN: 1108577415
Category : Medical
Languages : en
Pages : 263
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Book Description
Epilepsy is a prevalent and serious neurological disorder. This vital textbook addresses the role of neuroimaging as a unique tool to provide in vivo biomarkers aimed at furthering our understanding of causes and consequences of epilepsy in a day-to-day clinical context. Unique in its approach, this translational book presents a critical appraisal of advanced pre-clinical biomarkers that allows capturing epileptogenesis at molecular, cellular, and neuronal system levels. The book is divided into four sections. Part I includes a series of chapters focused on imaging of early disease stages. Part II discusses lesion detection and network analysis methods. Part III focuses on imaging methods used to predict response to antiepileptic drugs and surgery. Finally, Part IV presents imaging techniques used to evaluate disease consequence.
Author: Issam A. Awad
Publisher: Thieme
ISBN: 9781879284074
Category : Medical
Languages : en
Pages : 250
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Book Description
The massive convergence of information about cavernous malformations has been synthesized in this volume by experts in the field of pathology, neuroradiology and neurosurgery. Cavernous Malformations represents state-of-the-art knowledge about this lesion and the spectrum of opinion about its nature, clinical behavior and management strategies. Highlights of Cavernous Malformations: Definition and pathologic features Epidemiology Diagnostic imaging Epilepsy Hemorrhage Conservative management Surgical intervention Microsurgical treatments Spinal cavernous malformations Pediatrics Radiotherapy (Distributed by Thieme for the American Association of Neurological Surgeons)
Author: Horst Urbach
Publisher: Springer Science & Business Media
ISBN: 3642251382
Category : Medical
Languages : en
Pages : 270
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Book Description
MRI can play an important role in identifying and localizing epileptogenic foci. This book aims to provide the clinical and imaging information required in order to decide whether an MRI scan is appropriate and whether it is likely to be sufficient to detect a lesion. The first part of the book presents background information on epilepsy patients and explains how to perform an MRI examination. Detailed attention is paid to functional MRI and post-processing, and the examination of subcategories of patients is also discussed. The second part of the book then documents the MRI findings obtained in the full range of epileptogenic lesions with the aid of high-quality images. Throughout, emphasis is placed on guiding the reader in the correct interpretation of the imaging findings. Both radiologists and referring physicians will find this book to be an indispensable guide to the optimal use of MRI in epilepsy.
Author: Jan Trøst Jørgensen
Publisher: Academic Press
ISBN: 0128135409
Category : Medical
Languages : en
Pages : 509
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Book Description
Companion and Complementary Diagnostics: From Biomarker Discovery to Clinical Implementation provides readers with in-depth insights into the individual steps in the development of companion diagnostic assays, from the early biomarker discovery phase straight through to final regulatory approval. Further, the clinical implementation of companion diagnostic testing in the clinic is also discussed. As the development of predictive or selective biomarker assays linked to specific drugs is substantially increasing, this book offers comprehensive information on this quickly-evolving area of biomedicine. It is an essential resource for those in academic institutions, hospitals and pharma, and biotech and diagnostic commercial companies. - Covers all aspects, from biomarker discovery, to development and regulatory approval - Explains the "how to" aspects of companion diagnostics - Incorporates information on the entire process, allowing for easier and deeper understanding of the topic
Author: Jeffrey Noebels
Publisher: OUP USA
ISBN: 0199746540
Category : Medical
Languages : en
Pages : 1258
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Book Description
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Author: Donald L. Schomer
Publisher: Lippincott Williams & Wilkins
ISBN: 1451153155
Category : Medical
Languages : en
Pages : 1308
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Book Description
The leading reference on electroencephalography since 1982, Niedermeyer's Electroencephalography is now in its thoroughly updated Sixth Edition. An international group of experts provides comprehensive coverage of the neurophysiologic and technical aspects of EEG, evoked potentials, and magnetoencephalography, as well as the clinical applications of these studies in neonates, infants, children, adults, and older adults. This edition's new lead editor, Donald Schomer, MD, has updated the technical information and added a major new chapter on artifacts. Other highlights include complete coverage of EEG in the intensive care unit and new chapters on integrating other recording devices with EEG; transcranial electrical and magnetic stimulation; EEG/TMS in evaluation of cognitive and mood disorders; and sleep in premature infants, children and adolescents, and the elderly. A companion website includes fully searchable text and image bank.
Author: Nicole Seiberlich
Publisher: Academic Press
ISBN: 0128170581
Category : Computers
Languages : en
Pages : 1094
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Book Description
Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: - The basic physics behind tissue property mapping - How to implement basic pulse sequences for the quantitative measurement of tissue properties - The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* - The pros and cons for different approaches to mapping perfusion - The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor - maps and more complex representations of diffusion - How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed - How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance - Fingerprinting can be used to accelerate or improve tissue property mapping schemes - How tissue property mapping is used clinically in different organs - Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds - Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements - Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges - Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
