Author:
Publisher:
ISBN:
Category : Engineering
Languages : en
Pages : 514

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Author:
Publisher:
ISBN:
Category : Engineering
Languages : en
Pages : 718

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Author: Wei-Shu Hu
Publisher: Springer
ISBN: 3540340076
Category : Science
Languages : en
Pages : 179

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Book Description
Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the ?rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the ?rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi?cations on proteins could only be ef?ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie?y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade.

Author: IEEE Staff
Publisher:
ISBN: 9781728187518
Category :
Languages : en
Pages :

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The tenth International Conference on Image Processing Theory, Tools and Applications IPTA 2020 aims at gathering international researchers, innovators, educators, and practitioners in image processing for attending extensive educational high level materials, sharing their achievements, exchanging their experiences and discussing future orientations The conference aims to provide an excellent forum to meet and discuss various important issues on image processing and applications

Author: A.H.C. Ng
Publisher: IOS Press
ISBN: 1643682695
Category : Technology & Engineering
Languages : en
Pages : 874

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Book Description
The realization of a successful product requires collaboration between developers and producers, taking account of stakeholder value, reinforcing the contribution of industry to society and enhancing the wellbeing of workers while respecting planetary boundaries. Founded in 2006, the Swedish Production Academy (SPA) aims to drive and develop production research and education and to increase cooperation within the production area. This book presents the proceedings of the 10th Swedish Production Symposium (SPS2022), held in Skövde, Sweden, from 26-29 April 2022. The overall theme of the symposium was ‘Industry 5.0 Transformation – Towards a Sustainable, Human-Centric, and Resilient Production’. Since its inception in 2007, the purpose of SPS has been to facilitate an event at which members and interested participants from industry and academia can meet to exchange ideas. The 69 papers accepted for presentation here are grouped into ten sections: resource-efficient production; flexible production; humans in the production system; circular production systems and maintenance; integrated product and production development; industrial optimization and decision-making; cyber-physical production systems and digital twins; innovative production processes and additive manufacturing; smart and resilient supply chains; and linking research and education. Also included are three sections covering the Special Sessions at SPS2022: artificial intelligence and industrial analytics in industry 4.0; development of resilient and sustainable production systems; and boundary crossing and boundary objects in product and production development. The book will be of interest to all those involved in the development and production of future products.

Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 474

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Author: K. Säfsten
Publisher: IOS Press
ISBN: 1643681478
Category : Technology & Engineering
Languages : en
Pages : 706

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Book Description
Knowledge-intensive product realization implies embedded intelligence; meaning that if both theoretical and practical knowledge and understanding of a subject is integrated into the design and production processes of products, this will significantly increase added value. This book presents papers accepted for the 9th Swedish Production Symposium (SPS2020), hosted by the School of Engineering, Jönköping University, Sweden, and held online on 7 & 8 October 2020 because of restrictions due to the Corona virus pandemic. The subtitle of the conference was Knowledge Intensive Product Realization in Co-Operation for Future Sustainable Competitiveness. The book contains the 57 papers accepted for presentation at the conference, and these are divided into nine sections which reflect the topics covered: resource efficient production; flexible production; virtual production development; humans in production systems; circular production systems and maintenance; integrated product and production development; advanced and optimized components, materials and manufacturing; digitalization for smart products and services; and responsive and efficient operations and supply chains. In addition, the book presents five special sessions from the symposium: development of changeable and reconfigurable production systems; smart production system design and development; supply chain relocation; management of manufacturing digitalization; and additive manufacturing in the production system. The book will be of interest to all those working in the field of knowledge-intensive product realization.

Author:
Publisher:
ISBN:
Category : Econometric models
Languages : en
Pages :

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Author: Van Nam Huynh
Publisher: Springer Science & Business Media
ISBN: 3319027417
Category : Technology & Engineering
Languages : en
Pages : 422

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Book Description
The field of Knowledge and Systems Engineering (KSE) has experienced rapid development and inspired many applications in the world of information technology during the last decade. The KSE conference aims at providing an open international forum for presentation, discussion and exchange of the latest advances and challenges in research of the field. These proceedings contain papers presented at the Fifth International Conference on Knowledge and Systems Engineering (KSE 2013), which was held in Hanoi, Vietnam, during 17–19 October, 2013. Besides the main track of contributed papers, which are compiled into the first volume, the conference also featured several special sessions focusing on specific topics of interest as well as included one workshop, of which the papers form the second volume of these proceedings. The book gathers a total of 68 papers describing recent advances and development on various topics including knowledge discovery and data mining, natural language processing, expert systems, intelligent decision making, computational biology, computational modeling, optimization algorithms, and industrial applications.

Author: Odhiambo, Marcel Ohanga
Publisher: IGI Global
ISBN: 1799893138
Category : Computers
Languages : en
Pages : 263

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Book Description
As the internet of things market is booming, several issues are delaying the full realization of the technology. Currently, business competitors are jockeying for a piece of the market, meaning solutions from researchers that address these issues is crucial for internet of things technology developers. Overpromising followed by underdelivering has been the current approach by many innovators, and the mismatch results in losses in production, orphaned technologies, and frequent system failures. Solutions that address internet of things performance issues must be studied in order to take full advantage of this emerging market. Achieving Full Realization and Mitigating the Challenges of the Internet of Things addresses the challenges faced in rolling out internet of things technologies as well as the various performance issues. Covering a range of topics such as cybersecurity and connectivity issues, this reference work is ideal for industry professionals, academicians, researchers, practitioners, technology developers, instructors, and students.