Identification and Characterization of a Novel Protein that Interacts with the 50-kDa Subunit of Human DNA Polymerase [delta] and PCNA PDF Download
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![Identification and Characterization of a Novel Protein that Interacts with the 50-kDa Subunit of Human DNA Polymerase [delta] and PCNA PDF](https://books.google.com/books/content/images/frontcover/lkr1tgAACAAJ?fife=w150-h200)
Author: Hua He
Publisher:
ISBN:
Category : DNA polymerases
Languages : en
Pages : 214
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Book Description
![Identification and Characterization of a Novel Protein that Interacts with the 50-kDa Subunit of Human DNA Polymerase [delta] and PCNA PDF](https://books.google.com/books/content/images/frontcover/lkr1tgAACAAJ?fife=w80-h100)
Author: Hua He
Publisher:
ISBN:
Category : DNA polymerases
Languages : en
Pages : 214
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Book Description
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 820
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Author: Alexander Rodney Abbas
Publisher:
ISBN:
Category :
Languages : en
Pages : 316
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Author:
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 1074
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Author: Nayef Ali Mazloum
Publisher:
ISBN:
Category :
Languages : en
Pages : 162
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Book Description
![Human DNA Polymerase [epsilon] Associated Proteins PDF](https://books.google.com/books/content/images/frontcover/k_1OJgAACAAJ?fife=w80-h100)
Author: Minna Mäkiniemi
Publisher:
ISBN: 9789514259685
Category :
Languages : en
Pages : 68
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Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1476
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Author:
Publisher:
ISBN:
Category : Genetics
Languages : en
Pages : 634
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Author: Giovanni Maga
Publisher: World Scientific
ISBN: 9813226420
Category : Science
Languages : en
Pages : 398
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Book Description
Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, next generation sequencing, nucleic acids based diagnostics and in techniques to analyze ancient and otherwise damaged DNA (e.g. for forensic applications). Moreover, some diseases are related to DNA polymerase defects and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. This book focuses on (i) biology of DNA polymerases, (ii) medical aspects of DNA polymerases and (iii) biotechnological applications of DNA polymerases. It is intended for a wide audience from basic scientists, to diagnostic laboratories, to companies and to clinicians, who seek a better understanding and the practical use of these fascinating enzymes.
Author: Christopher W. Lawrence
Publisher: Springer Science & Business Media
ISBN: 1468443828
Category : Medical
Languages : en
Pages : 433
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Book Description
Concern is often expressed that our environment may include an increasingly large variety of mutagens, but the extent of the potential hazard they pose has yet to be fully evaluated. A variety of empirical procedures has been devised with which to estimate the mutagenic potency of suspect agents, and the relative merits of different tests are currently under debate. Although such tests are of great value, and are indeed indispensable, they are not, nevertheless, sufficient. In the long term, accurate estimation of hazard will also require a better understanding of the various mechanisms of mutagenesis, and in many instances these remain remarkably elusive. Our knowledge and appreciation of the problem has increased substantially over the last few years, but the precise way in which many mutagens cause mutations is not yet known. The aims of this conference were therefore two-fold. The first was to survey present information about mutagenic mechanisms, drawing together data from work with various experimental approaches and organisms, in order to discern the principles governing the action of different mutagens. The second was to examine the implications of such principles for the execution and evaluation of test procedures, and critically assess the research areas that need further attention in order to improve the interpretation of test results. Chris Lawrence v ACKNOWLEDGEMENT We gratefully acknowledge the support provided for this Conference by the U.,S. Department of Energy, The Foundation for Microbiology, Exxon Corporation and the University of Rochester.
